1-[ethyl(hydroxymethyl)amino]ethane-1,2-diol

Details:

Common name: Tris(hydroxymethyl)aminomethane

Category:Pharmaceutical Intermediates

Other name: /

CAS No.: 77-86-1

EINECS No.: 201-064-4

Appearance: Crystal

Molecular formula: C4H11NO3

 

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

 

Product Specification:

Molecular Weight	121.14
Boiling point	219-220 °C10 mm Hg(lit.)
Melting point	167-172 °C(lit.)
Density	1.353 g/cm3
Purity	≥99.0%
PH	10.5-12.0(4 m in water, 25 °C)
Acidity coefficient (pKa)	8.1(at 25℃)
Soluble	/
Water solubility	550 g/L (25 °C)
Color	White

 

 

Product Description:
Tris(hydroxymethyl)aminomethane, commonly abbreviated as Tris, is a highly versatile and widely used organic compound. It typically presents as a white crystalline powder, which is highly soluble in water, making it convenient for use in aqueous - based solutions. Structurally, it contains an amino group and three hydroxymethyl groups. This unique structure endows it with excellent buffering properties.

In the field of biochemistry and molecular biology, Tris is an essential component in buffer systems. It is used to maintain a stable pH in various biological reactions, such as DNA and RNA isolation, protein purification, and enzyme assays. Its buffering capacity is effective in the pH range of approximately 7.0 - 9.0, which is suitable for many biological processes. In the pharmaceutical industry, it can be used as an excipient in drug formulations, helping to adjust the pH and enhance the stability of drugs. Additionally, in the field of electrophoresis, Tris - based buffers are commonly used to ensure proper separation of biomolecules. Our Tris (hydroxymethyl) aminomethane product is produced through a carefully optimized manufacturing process. Stringent quality control measures are implemented to guarantee high purity, consistent quality, and reliable performance, making it a reliable choice for laboratories, pharmaceutical companies, and other industries with related needs.

 

 

Application: 

Tris(hydroxymethyl)aminomethane, or Tris, has diverse applications. In biochemistry and molecular biology, it's crucial for buffer systems. It maintains stable pH in DNA/RNA isolation, protein purification, and enzyme assays, functioning well in the pH range of about 7.0 - 9.0. In the pharmaceutical industry, it serves as an excipient to adjust drug pH and enhance stability. Also, in electrophoresis, Tris - based buffers help separate biomolecules effectively.

Package: 25kg/drum or bag

Storage: Sealed in dry, room temperature

Executive Standards: International Standard.