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Keywords
GLP-1 tirzepatide mounjaro
Quick Details
- Appearance:off white powder
- Application:for research use only
- PackAge:carton
- ProductionCapacity:1000|bottle|Week
- Storage:-20degree to room temperature
- Transportation:room temperature
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Details:
Tirzepatideis a medication approved for the treatment of type 2 diabetes mellitus and chronic weight management. Below is a structured overview of its key aspects:
Mechanism of Action
Dual Agonist: Activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)receptors. This dual action enhances:
- Insulin secretion (in a glucose-dependent manner).
- Suppression of glucagon(reduces liver glucose production).
- Gastric emptying delay(lowers post-meal blood sugar spikes).
- Appetite reduction (promotes satiety and weight loss).
**Approved Uses**
1. **Type 2 Diabetes**: Lowers blood sugar and HbA1c levels.
2. **Weight Management**:
- For adults with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related conditions (e.g., hypertension, dyslipidemia).
- Clinical trials (e.g., SURPASS, SURMOUNT) demonstrated significant weight loss (up to 15–22% of body weight in some studies).
**Administration**
- **Dosage**: Once-weekly subcutaneous injection.
- **Diabetes**: Initial dose of 2.5 mg, titrated up to 15 mg.
- **Weight Management**: Doses range from 5 mg to 15 mg weekly.
- **Storage**: Refrigerated (unused pens); can be stored at room temperature for up to 21 days.
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