Amiodarone hydrochl...

Amiodarone hydrochloride
Amiodarone hydrochloride
Amiodarone hydrochloride
Amiodarone hydrochloride

Amiodarone hydrochloride

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: USP/EP/BP
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Keywords

Ketone,2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl,hydrochloride (7CI,8CI) Methanone,(2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-,hydrochloride (9CI) 19774-82-4

Quick Details

  • Appearance:White crystallization
  • Application:Cardiovascular APIs,Sartan antihypertensive drugs
  • PackAge:25kg/drum
  • ProductionCapacity:10|Metric Ton|Day
  • Storage:room temperature
  • Transportation:AIR SEA TRAIN

Superiority:

Product Name: Amiodarone hydrochloride
Synonyms: 2-BUTYL-3-BENZOFURANYL 4-[2-(DIETHYLAMINO)ETHOXY]-3,5-DIIODOPHENYL KETONE HYDROCHLORIDE;(2-BUTYL-3-BENZOFURANYL)-[4-[2-(DIETHYLAMINO)ETHOXY]-3,5-DIIODO-PHENYL]-METHANONE HYDROCHLORIDE;AMIODARONE-D4 HCL;AMIODARONE HCL;AMIODARONE HYDROCHLORIDE;AMIODARONUM HYDROCHLORIDE;2-butyl-3-benzofuryl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride;AMIODARONEHCL(2-BUTYL-3-BENZOFURANYL-4-[2-(DIETHYLAMINO)ETHOXY]-3,5-DIIODOPHENYLKETONE)
CAS: 19774-82-4
MF: C25H29I2NO3.ClH
MW: 681.77
EINECS: 243-293-2
Product Categories: API;API's;Ion transporter and other ion channel;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Active Pharmaceutical Ingredients;19774-82-4
Mol File: 19774-82-4.mol
Amiodarone hydrochloride Structure
 
Amiodarone hydrochloride Chemical Properties
Melting point  154-158°C
Fp  9℃
storage temp.  2-8°C
solubility  Soluble in chloroform, methanol.
pka pKa (25°C) 6.56 ±0.06
form  Solid
color  White
λmax 242nm(MeOH)(lit.)
Merck  14,482
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Details:

Amiodarone hydrochloride Usage And Synthesis
Description Amiodarone HCl (19774-82-4) is a nonselective ion channel blocker. Class III antiarrhythmic.1 Induces cytochrome c release and induces apoptosis.2 An alkalizing agent which stimulates progranulin (GRN) production and prevents GRN-dependent neurodegeneration.3 Induces autophagy and suppresses hepatocellular carcinoma tumorigenesis via autophagy-mediated MIR224 degradation in vitro and in vivo.4
Chemical Properties White Solid
Originator Cordarone,Labaz,France,1971
Uses Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.
Uses Antiarrhythmic;Na+ channel blocker
Uses A non-selective ion channel blocker. Antiarrhythmic (class III)
Uses Amiodarone hydrochloride is a non-selective ion channel blocker with broad fungicidal activity. Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death. Amiodarone hydrochloride has also been used in a study to determine concentrations of thyroid disrupting substances in effluents from wastewater treatment plants.

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