(2-Hydroxypropyl)tr...

(2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI)
(2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI)
(2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI)
(2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI)

(2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI)

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: USP/EP/BP
  • Payment Terms : L/C,T/T,Other

Keywords

Bethanechol 1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (9CI) 590-63-6

Quick Details

  • Appearance:White crystallization
  • Application:Cardiovascular APIs,Sartan antihypertensive drugs
  • PackAge:25kg/drum
  • ProductionCapacity:10|Metric Ton|Day
  • Storage:room temperature
  • Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on Bethanechol.Our mfr is GMP certified for this item with DMF document. 

 

Product Name: Bethanechol
Synonyms: (2-hydroxypropyl)trimethylammoniumchloridecarbamate;2-((aminocarbonyl)oxy)-n,n,n-trimethyl-1-propanaminiuchloride;2-[(aminocarbonyl)oxy]-n,n,n-trimethyl-1-propanaminiuchloride;ammonium,(2-hydroxypropyl)trimethyl-,chloride,carbamate;beta-methylcholinechlorideurethan;bethainecholinechloride;carbaminoyl,beta-methylcholinechloride;carbamyl-b-methylcholinechloride*crystalline
CAS: 590-63-6
MF: C7H17ClN2O2
MW: 196.68
EINECS: 209-686-8
Product Categories: Coumarins ,Pyrans;Inhibitors;DUVOID;Acetylcholine receptor;Aliphatics;Amines;Intermediates & Fine Chemicals;Pharmaceuticals;590-63-6
Mol File: 590-63-6.mol
Bethanechol Structure
 
Bethanechol Chemical Properties
Melting point  187-190°C
storage temp.  Inert atmosphere,2-8°C
solubility  H2O: 1.7 g/mL stable for several days at 4°C.
form  crystalline
color  white
Water Solubility  H2O: 1.7g/mL (stable for several days at 4°C.)
ethanol: 80mg/mL (stable for several days at 4°C.)

Details:

Bethanechol Usage And Synthesis
Description Bethanechol is an agonist of muscarinic acetylcholine receptors with IC50 values of 1,837, 25, 631, 317, and 393 μM for M1-5, respectively, in a radioligand binding assay using CHO cells expressing the human receptors. It inhibits M2-mediated increases in cyclic AMP induced by isoproterenol in isolated guinea pig small intestine (IC50 = 127 μM). Bethanechol increases basal tone of isolated porcine intravesical ureter (EC50 = 4.27 μM). It also induces fluid secretion in the ileum, duodenum, and jejunum of anesthetized rats when administered at a dose of 60 μg/kg. Formulations containing bethanechol have been used to increase urination and improve smooth muscle tone in the gastrointestinal tract.
Chemical Properties White Solid
Originator Urecholine CI,MSD,US,1949
Uses cholinergic
Uses A selective muscarinic receptor stimulant, used to treat cerebral palsy.
Uses Therapeutic action of Betanechol is based on this action, and it is used for treating postoperational non-obstructive retention of urine and neurogenic bladder atony. Earlier, it was used for treating gastrointestinal illnesses and Alzheimer’s disease.

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