Min.Order / FOB Price:Get Latest Price
1 Kilogram |
FOB Price:USD 48.0000 -58.0000 |
1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,[3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)]- FORSKOLIN FROM COLEUS FORSKOHLII (-)-Forskolin
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Molecular Formula | C22H34O7 |
Molar Mass | 410.5 |
Density | 1.23 |
Melting Point | 282-232 °C |
Boling Point | 520℃ |
Specific Rotation(α) | D25 -26.19° (c = 1.68 in CHCl3) |
Flash Point | 172℃ |
Water Solubility | Soluble in ethanol, dimethylsulfoxide and chloroform. Insolule in water. |
Solubility | Soluble in methanol, DMSO |
Appearance | White powder |
Color | off-white |
Maximum wavelength(λmax) | ['305nm(lit.)'] |
Merck | 14,2476 |
BRN | 1692716 |
pKa | 11.00±0.70(Predicted) |
Storage Condition | room temp |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months. |
Refractive Index | 1.5300 (estimate) |
MDL | MFCD00082317 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Coleus forskohlii. |
In vitro study | Forskolin can make the content of cAMP in membrane, cell or tissue preparation liquid rise. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters and ion channels. Forskolin can promote the activation of 9 different independent AC forms, although the efficiency of AC9 is a bit low, which can be used to provide an identification and quantification of G protein (G s) methods for high affinity binding sites for the-AC complex. G protein-coupled receptor activation G protein contributes to Forskolin-stimulated cAMP production in cells because G protein-Forskolin has a potentiating effect on AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. In adipocytes, Forskolin's promotes the production of cAMP, which in turn can inhibit the degranulation of basophils and mast cells and the release of histamine, reduce blood pressure and intraocular pressure, inhibit platelet aggregation, and promote vasodilation, bronchiectasis and thyroid hormone secretion, stimulate lipolysis. Forskolin inhibits the binding of platelet activating factor (PAF), which is independent of cAMP formation. This inhibition may be achieved by Forskolin's acting directly on PAF or by interfering with the binding of PAF to its receptor. Forskolin also appears to have an effect on a variety of membrane transport proteins and can inhibit glucose transport in adipocytes, erythrocytes, platelets, and other cells. Forskolin is also used to treat glaucoma. |
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
6. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
7. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
8. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
9. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
10. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.
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