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6-bromo-1-methyl-1H-Imidazo[4,5-b]pyridine heterocyclic building block imidazopyridine compound
Versatile Brominated Heterocycle for Medicinal Chemistry
High synthetic value – bromine at position 6 enables easy functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
Fused heterocyclic scaffold – imidazo[4,5-b]pyridine core is common in biologically active molecules, especially kinase inhibitors and CNS-targeting compounds.
Methyl substitution at N1 – enhances lipophilicity and modifies pharmacokinetic profiles in drug development.
Pharma-grade purity – suitable for use in research and preclinical pharmaceutical synthesis.
Stable and easy to handle – solid form with good shelf life and compatibility in standard reaction conditions.
6-Bromo-1-methyl-1H-imidazo[4,5-b]pyridine is a brominated heterocyclic compound featuring a fused imidazopyridine core. Substituted with a methyl group at the nitrogen atom (N1) and a bromine atom at position 6, it offers excellent reactivity and selectivity in cross-coupling and heterocycle modification reactions.
This compound is widely recognized as a key intermediate in the synthesis of biologically active molecules, including kinase inhibitors, anti-inflammatory agents, and CNS-active drugs. Its fused aromatic structure mimics purine-like systems, making it particularly valuable in medicinal chemistry and drug discovery.
With high purity and good chemical stability, 6-bromo-1-methyl-1H-imidazo[4,5-b]pyridine is ideal for pharmaceutical R&D, custom synthesis, and production of advanced intermediates.
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