Details:

Vinpocetine (Ph.F), CAS NO. 42971-09-5

Vinpocetine (Ph.F), CAS NO. 42971-09-5

Applications


 Vasodilatory action measured by an inhibition of the phosphodiesterase 
activity increase in the levels of AmpC, with an increase of the blood flow 
by diminishing the vascular resistance.

 Antiplatelet action.

 Improvement of the hemorheological conditions in the microcirculation 
upon increasing the deformability of the erythrocytes.

Brain cells' increased tolerance to hypoxia (lack of oxygen in the brain) 
and/ischemia (permanent transitory decrease of blood flow).

 Increase in the levels of oxygen use of glucose in the neurons.

 Improvement in terms of production of neurotransmitters such as dopamine 
noradrenaline, to which its nootropic effect has been attributed.

Specifications

Name of the plant Voacanga africana
Part of the plant used Seeds
Formula C22H26N2O2
IUPAC Name Eburnamenine-14-carboxylic acid ethylester
Synonyms Ethyl-apovincaminate; (3 , 16 ) - Eburnamenine-14-carboxylic 
acid ethyl ester.
Molecular Weight 350.46 g/mol
CAS N. 42971-09-5
Structural Formula

Appearance

White to slightly yellow crystals, crystalline powder, 
odourless
Solubility Practically insoluble in water, soluble in methylene chloride, 
slightly soluble in anhydrous ethanol
Melting point Between 150° 153°C
Identification IR
Specific optical rotation Between + 127 + 134
Absorbance E1%1cm (254 nm) Between 330 343
Loss on drying NMT 0.20 %
Sulphated ash NMT 0.10 %
Heavy Metals NMT 10 ppm
Sulphates NMT 0.03 %
Assay Between 99.0 % 101.0 %
Microbiology Complies with EP
Storage Sealed container protected from light