Piroctone Olamine(octopirox)

Details:

Company Profile:
Company Name: AURORA CHEMICAL CO., LTD.    
Year Established: 1997
The world’s leading manufacturer and supplier of Xanthan Gum, Oil Driling Chemicals, Drilling Fluid Additives, Rubber Plastic Additives and Cosmetic Ingredients.

Piroctone Olamine(octopirox)

CAS No:68890-66-4

Molecular Formula:C14H23NO2·C2H7NO

Structural Formula:

Property:

The scalp depends itself against micro-organisms fungus infections. The defence system protects the scalp against all kinds of influences that it is expose to. Sometimes this defence system becomes weakened a certain fungus infection develops called Pityrosporum Ovale. This fungus infection causes considerable cell multiplication. The skin is no longer in a position to defend itself; the scaling becomes rapid, starts to gather on the scalp. A superfluous cell situation mixing with skin sebum causes dandruffto be formed. People with dandruff experience itchiness of the scalp. Besides this, theirproblem is very often an ongoing one.

Piroctone Olamine is an anti-dandruff active ingredient, soothes inflamed scalp reduces flaking. It has a specific action against Pityrosporum Ovale, the agent responsible fthe production of dandruff. The anti-dandruff product containing Piroctone Olamine destroys the fungus infection that is responsible fthe dandruff works against the formation of new dandruff, makes the scalp stays clean, itch free prevents the formation of new dandruff, you become free of all the inconvenience relating to dandruff.

After six weeks of treatment, the scalp dandruff decreased 81.7 % by using a shampoo containing 0.5% DF-206, 68.6% by a 0.5% Zinc pyrithione shampoo.
 

Specification:

Appearance:                    White slightly yellow crystalline powder

Identification:                   Positive

Od:                               Almost odorless

Content:                           Not less than 98%

Melting point:                   130 - 135°C

Loss on drying:              Not more than 0.3%

Ash (SO4):                      Not more than 0.2%

pH value (1% aq. solu. 20°C):      8.5 – 10.0

Heavy metals:                   Not more than 20ppm

Amino Ethanol:                 20.1 to 20.9% dried base

Solubility:      Freely soluble in 10% ethanol in water; soluble in solution containing surfactants in water in 1%-10% ethanol; slightly soluble in water in oil. The solubility in water varies by pH value, is a litter larger in neutral weak basic solution than in acid solution.

Thickening:     Piroctone Olamine increases the viscosity of many surfactant system

Stability:

a). pH: Stable in solution of pH 3 to pH 9.

b). Heat: Stable to heat, to short time of high temperature above 80°C. DF-206 in shampoo of pH 5.5-7.0 remains stable after one year of storage at a temperature over 40°C.

c). Light: Decompose under direct ultraviolet radiation. So it should be protected from light.

d). Metals: An aqueous solution of Piroctone Olamine degrades in the presence of cupric ferric ions.

Compatibility: Piroctone Olamine is compatible with many cosmetic ingredients,especially with cationic surfactants (tetramine salt) cationic active components. In some cases, this re-mixture increase the solubility of Piroctone Olamine.

Uses:

Piroctone Olamine is a broad spectrum of microbiocide/microbiostat, may be used informulating antidandruff shampoo, hair keep hair care, soap, etc.

Rate of Application

Antidandruff hair keep:       0.1-0.8% active ingredient.

Antidandruff fixing agent:       0.05-0.2% active ingredient.

Antidandruff hair emulsion:      0.1-0.3% active ingredient.

Antidandruff hair supporting :    0.05-0.1%active ingredient.

Preservative :                 0.2-0.5% active ingredient

Smell-eliminating agent:        0.2-0.5% active ingredient

Smell-eliminating scented soap:  0.2-0.5% active ingredient.