Budesonide

Budesonide is a local application does not contain halogen adrenal cortical hormone drugs, has significant anti-inflammatory, anti allergic, antipruritic and anti exudation of the role. The local action and dipropionate beclomethasone dipropionate are the same. It is mainly used in the past used bronchodilator or anti allergy medicine failed to very good control of bronchial asthma. This product can relieve bronchial spasm, aerosol inhalation of the lung has anti-inflammatory effect, long-term use of good tolerance, can reduce the dosage of oral adrenal cortex hormone, and without the systemic effect of corticosteroids. Similar to the effect of bronchial asthma in children and adults with dipropionate times beclomethasone, curative effect is better, and can tolerate long-term, on glucocorticoid dependent or non dependent asthma aerosol inhalation can control of asthma and can effectively prevent recurrence, inhalation in the treatment of 3 to 6 months, visible improvement in lung function, frequency of acute attack reduced and plasma corticosterone concentration can be recovery and increased gradually, while the daily dosage of oral corticosteroids can reduce 40% ~ 50%. Therefore, the patients with glucocorticoid dependent asthma, especially with large dosage, were the ideal drugs for oral administration.. Effect of glucocorticoid budesonide is strong, while the mineralocorticoid effect is weak. Animal experiments show that the drug on glucocorticoid receptor affinity for cortisol 200 times, when applied topically anti-inflammatory effect of 1000 times as cortisone, and anti-inflammatory effects of subcutaneous and oral only than cortisone were 40 and 25 times.