Sorafenib Nexavar;Bay 43-9006 284461-73-0
Sorafenib
SorafenibSorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro. IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1] Target: Raf-1 Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).Sorafenib
SorafenibSorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro. IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1] Target: Raf-1 Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
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