Add time:07/30/2019         Source:sciencedirect.com

Michael addition of dibenzylamine to (−)- and (+)-tert-butyl myrtenate, (−)-2 and (+)-2, derived from (−)- and (+)-myrtenal, furnished monoterpene-based β-amino acid derivatives in highly stereospecific reactions. The resultant amino esters (−)-3 and (+)-3 were transformed to unsubstituted, mono- and disubstituted and Fmoc-protected amino acids (−)-6-11 and (+)-6-11, which are promising building blocks for the synthesis of β-peptides and 1,3-heterocycles. The microwave-assisted conjugate addition of nitromethane to α,β-unsaturated esters (−)-12 and (+)-12 likewise resulted in nitro esters (−)-13 and (+)-13 in highly stereospecific reactions. Compounds (−)-13 and (+)-13 were successfully transformed into γ-amino acids (−)-16 and (+)-16 in two steps.

We also recommend Trading Suppliers and Manufacturers of 6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-carboxylic acid (cas 19250-17-0). Pls Click Website Link as below: cas 19250-17-0 suppliers