Add time:08/10/2019         Source:sciencedirect.com

In this study, the synthesis of some new 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H)-pyrimidinones has been reported. The compounds were prepared by the Biginelli reaction of acetylacetone with aromatic aldehydes and urea. The structures of the compounds were characterized by UV, IR, 1H NMR, 13C NMR, mass spectra and elementary analysis. The calcium antagonistic activity of these compounds was tested in vitro on rat ileum precontracted with 4×10−3 M barium chloride.

We also recommend Trading Suppliers and Manufacturers of 6-METHYL-2-PHENYL-4(1H)PYRIMIDINONE (cas 13514-79-9). Pls Click Website Link as below: cas 13514-79-9 suppliers