Add time:08/25/2019         Source:sciencedirect.com

Chiral separation of 3,4-dihydro-2H-1-benzopyran derivatives by capillary zone electrophoresis was achieved by employing β-cyclodextrin (β-CD) as chiral selector. The effects of electrolyte composition (β-cyclodextrin concentration, ionic strength and pH of the buffer) on the migration time, enantioselectivity, peak efficiency and resolution were investigated. As expected, there was an optimum β-CD concentration (Copt) which gave maximum enantioselectivity. The stability constant for the β-CD inclusion complex was determined for each enantiomer of two 3,4-dihydro-2H-1-benzopyran derivatives. For each solute, the experimental value of Copt agreed well with the value calculated from the equation [C]opt = 1/(KRKS)12, where we used experimental values for the inclusion complex constants (KR, KS). The enantiomeric separation of three 3,4-dihydro-2H-1-benzopyran derivatives was achieved using this optimization method, and baseline separation was obtained in less than 15 min with an efficiency of between 300 000 and 600 000 theoretical plates.

We also recommend Trading Suppliers and Manufacturers of 2H-1-Benzopyran-8-aMine, 3,4-dihydro- (cas 113722-25-1). Pls Click Website Link as below: cas 113722-25-1 suppliers