Add time:08/23/2019         Source:sciencedirect.com

The alkylation of alkyl phosphinates and some H-phosphonate diesters is promoted by the base DBU. Only more reactive alkyl halides react in preparatively useful yields. However, the method provides easy access to important H-phosphinate building blocks, without the need for a protecting group strategy or metal catalysts. The reaction is conveniently conducted at, or below, room temperature. The preparation of methyl-H-phosphinate esters is particularly interesting as it avoids the heretofore more common use of methyldichlorophosphine MePCl2.

We also recommend Trading Suppliers and Manufacturers of D-A H-PHOSPHONATE) (cas 104684-74-4). Pls Click Website Link as below: cas 104684-74-4 suppliers