Original articleAn H-phosphonate strategy for the synthesis of 2′,3′-dideoxynucleoside triphosphates and homodinucleotides-Science-Chemical Encyclopedia-lookchem

Original articleAn H-phosphonate strategy for the synthesis of 2′,3′-dideoxynucleoside triphosphates and homodinucleotides
Add time:08/24/2019 Source:sciencedirect.com

The triphosphates and homodinucleotides of AZT and d4T have been efficiently synthesized from the corresponding nucleoside 5′-H-phosphonate monoesters via the reactive pyridinium phosphoramidate intermediates.

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