I2O5/DBU mediated direct α-phosphoryloxylation of ketones with H-phosphonates leading to α-hydroxyketone phosphates-Science-Chemical Encyclopedia-lookchem

I2O5/DBU mediated direct α-phosphoryloxylation of ketones with H-phosphonates leading to α-hydroxyketone phosphates
Add time:08/25/2019 Source:sciencedirect.com

A simple and convenient procedure has been developed for the construction of α-hydroxyketone phosphates via I2O5/DBU mediated direct α-phosphoryloxylation of ketones with H-phosphonates. This new reaction proceeds through three steps involving α-iodination of ketones, oxidation of H-phosphonates, and nucleophilic substitution of α-iodo ketones to access a series of α-hydroxyketone phosphates of biological importance.

We also recommend Trading Suppliers and Manufacturers of D-A H-PHOSPHONATE) (cas 104684-74-4). Pls Click Website Link as below: cas 104684-74-4 suppliers

Prev:Original articleAn H-phosphonate strategy for the synthesis of 2′,3′-dideoxynucleoside triphosphates and homodinucleotides
Next: Preparation, characterization and antioxidant activities of polymannuronic acid phosphate, H-phosphonate and sulfate)

Click to view details

Encyclopedia