Add time:08/31/2019         Source:sciencedirect.com

The tandem enantioselective Michael addition/cyclisation reaction of malononitrile and nitrovinylphenols was catalysed by a recoverable C3-symmetric cinchonine-squaramide organocatalyst 1a to afford the 2-amino-4H-chromene-3-carbonitrile derivatives in excellent yields (up to 95%) and with excellent enantioselectivities (up to 98% ee) under mild reaction conditions. Furthermore, this catalyst can be easily recovered four times without loss in activity or enantioselectivity.

We also recommend Trading Suppliers and Manufacturers of Cinchonine (cas 118-10-5). Pls Click Website Link as below: cas 118-10-5 suppliers