Catalyst and solvent-free amidation of inactive esters of N-protected amino acids-Science-Chemical Encyclopedia-lookchem

Catalyst and solvent-free amidation of inactive esters of N-protected amino acids
Add time:08/28/2019 Source:sciencedirect.com

A catalyst free procedure for the preparation of amides from inactive esters of N-protected amino acids and various amines is demonstrated under mild reaction conditions. Our effort to recover excess amine and generated alcohol is an approach towards environment friendly and cost effective synthesis under easy operational conditions.

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