Add time:09/04/2019         Source:sciencedirect.com

5-(2-Thienyl)valeric acid (TVA), a biotin analogue which can be easily prepared through chemical process, inhibited the growth of a biotin synthesizing Rhodotorula glutinis. The growth inhibition was reversed by the addition of biotin. Among biotin intermediates, dethiobiotin and 7,8-diaminopelargonic acid reversed the inhibition by TVA, while 7-keto-8-amino-pelargonic acid and pimelic acid did not. From these results, it was concluded that TVA is a biotin antagonist which probably acts as an inhibitor of biotin biosynthesis.

We also recommend Trading Suppliers and Manufacturers of DL-3-(2-thienyl)-beta-alanine (cas 18389-46-3). Pls Click Website Link as below: cas 18389-46-3 suppliers