Add time:09/07/2019 Source:sciencedirect.com
Asymmetric CC bond formation was effected by the oxidative coupling of two different ester enolates using (R)-(+)-1,1′-bi(2-naphthol) as a common tether which served to link together both ester moieties in an asymmetric environment. Reduction of the corresponding succinates afforded diastereomerically pure 2,3-disubstituted-1,4-butanediols.
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