Add time:09/24/2019         Source:sciencedirect.com

Poly(N-acryloyl glycinamide) (PNAGA) with a protein-like thermoresponsive gelation behavior in water has been developed as a high strength self-healable supramolecular polymer(SP) hydrogels recently. However, harsh conditions, such as high temperature treatment and long waiting time, were required for achieving the complete healing due to strong dual amide hydrogen bonding interactions. In this study, to create an autonomic rapid self-healing SP hydrogel, we deliberately introduced a methyl into the opposite side to dual amide to synthesize N-methacryloyl glycinamide (MNAGA) monomer. Rheological analysis, dynamic light scattering(DLS), Fourier transform infrared (FTIR) spectroscopy, and Gaussian calculation revealed that one substitution methyl caused a considerable perturbation to the hydrogen bonding interaction, thus leading to the increased starting gelling concentration and pronounced decrease in mechanical properties of PMNAGA hydrogel compared to PNAGA hydrogel. The PMNAGA hydrogel was shown to exhibit rapid autonomic reparability without any external intervention, and dynamic swelling measurement indicated this PMNAGA hydrogel could evolve from permanent to transient network due to the metastable hydrogen bonding crosslinkage, depending on its environmental temperature. This intriguing robust, autonomous healing and autolytic PMNAGA hydrogel holds great potential as a short-term embolic agent for blocking blood vessel and artificial tears for moistening eyes.

We also recommend Trading Suppliers and Manufacturers of Glycinamide hydrochloride (cas 1668-10-6). Pls Click Website Link as below: cas 1668-10-6 suppliers