Add time:10/01/2019 Source:sciencedirect.com
2-Chloropurine is the first purine, for which simultaneous enzymic oxidation along two different pathways has been established. Attack at either carbon atom 6 or 8 proceeds at the same rate. This phenomenon is ascribed to the mesomeric (+M) effect of the halogen in position 2, which exhibits pronounced aromatic properties.
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