Add time:09/30/2019         Source:infona.pl

The purpose of this study is to evaluate the efficacy and reliability of pharmacologic provocative testing with Methohexital (cas 151-83-7) (PPTM) using intraoperative neurophysiologic monitoring (IONM) in endovascular embolization procedures (EEPs).111 EEPs cases were retrospectively reviewed between 2014 and 2015. PPTM and IONM was performed in 70 cases. The data, including cerebrovascular territory tested, PPTM dose, IONM modalities, PPTM results, and postoperative neurologic outcomes were obtained via chart review.Mean age was 28.2years. 85.7% of the cases were cerebral arteriovenous malformations. Mean PPTM dose was 10.8mg. Two positive tests were detected; one causing widespread loss of SSEPs and TcMEPs, embolization was deferred; and other with burst-suppression EEG immediately after PPTM administration, with embolization done at a different site. There were no false negative cases. Thus, the negative predictive value was 1.0.Our results regarding PPTM and IONM indicate the following: it is safe: can aid in intraoperative management; is accurate in predicting postoperative neurologic outcome; and that it is a useful adjunct for EEPs.Use of PPTM combined with IONM has not been previously described in the literature. Our study provides evidence of the utility and safety of PPTM in EPPs.

We also recommend Trading Suppliers and Manufacturers of Methohexital (cas 151-83-7). Pls Click Website Link as below: cas 151-83-7 suppliers