Since brain ischemia is one of the leading causes of adult disability and death, neuroprotection of the ischemic brain is of particular importance. Acute neuroprotective strategies usually have the aim of suppressing glutamate excitotoxicity and an excessive N-methyl-d-aspartate (NMDA) receptor ...

The kynurenine pathway is a cascade of enzymatic steps generating biologically active compounds. l-kynurenine (l-KYN) is a central metabolite of tryptophan degradation. In the mammalian brain, l-KYN is partly converted to kynurenic acid (KYNA), which exerts multiple effects on neurotransmission....

Substitution of chlorine in 5-chloro-N-phenylpyrazine-2-carboxamide (1) with simple n-alkylamines yielded a series of 5-alkylamino-N-phenylpyrazine-2-carboxamides (propylamino to octylamino derivatives), which possessed similar or increased activity against Mycobacterium tuberculosis H37Rv compa...

2-Amino-3-phenylpyrazine is found to be a sensitive fluorescence labeling reagent for saccharides with a reducing end. The labeled monosaccharides show strong fluorescence under various pH conditions, and could be analyzed by both HPLC and HPCE techniques. Laser induced fluorescence detection is...

The lithium salts of the conjugated bases of 4-methoxy- and 4-acetylamino-2(1H)-pyrimidinones 1–3 undergo highly chemoselective N1-methylation or ethylation when treated with methyl- or ethylsulfate (hard electrophiles) in dry dioxane, while the use of DMF as solvent results in competitive O2-a...

Mammalian aminoacylase-1 (Acy1) participates in the breakdown of N-acetylated amino acids during intracellular protein catabolism. Acy1 is most abundantly expressed in the kidney tubular epithelium. Lately, Acy1 deficiency was identified in children with increased urinary excretion of several N-...

Zinc(II) chloride complex with 2-(N-acetylamino)-6-methylpyridine (L) [ZnLCl2] has been obtained by the reaction between ethanol solutions of L and ZnCl2. The complex has been characterized by a set of methods including elemental analysis, IR-spectroscopy, single-crystal X-ray diffraction analys...

In this work, experimental and theoretical study on the molecular structure and the vibrational spectra of 3-amino-2-bromopyridine (Compound I) and 4-amino-2-bromopyridine (Compound II) are presented. The vibrational frequencies of these compounds were obtained theoretically by DFT/B3LYP employi...

To improve the stability of the collagen, here we studied the interaction of chromium(III) polyphenolic complex, [Cr(GA)2] (GA: Gallic acid) with collagen using various spectroscopic techniques. Circular dichroism studies show that the [Cr(GA)2] and gallic acid did not induce any structural pert...

A chromium oxide green pigment was prepared by thermal decomposition of chromium hydroxide via hydrothermal reduction of a high concentration mixture of Na2CrO4 (300 g/L) using NaHCO3 as a mineralizer. The mineralizer effects on the hydrothermal process, conversion of chromate, properties of amo...

Chromium is a common contaminant of soils and aquifers and constitutes a major environmental problem. In nature, chromium usually exists in the form of two oxidation states, trivalent, Cr(III), which is relatively innocuous for biota and for the aquatic environment, and hexavalent, Cr(VI) which ...

The physicochemical properties of several chromium(III) complexes with ligands, such as picolinate, dipicolinate, oxalate, 2,2′-bipyridine, and 4,4′-dimethoxy-2,2′-bipyridine were investigated. First, the stability and formation constants of the synthesised chromium(III) complexes in aqueous ...

Chromic oxide was synthesized through the dehydration and thermal decomposition of nanocrystalline and amorphous chromium hydroxide. The dehydration of amorphous chromium hydroxide had been researched clearly over the past few decades. Here, we mainly explored the different dehydration process b...

Reduction of hexavalent Cr(VI) to the trivalent state is the common strategy for remediation of Cr(VI) contaminated waters and soils. In the presence of Fe the resulting compounds are usually mixed Fe(III)–Cr(III) phases, while, under iron-free conditions, reduction leads to formation of plain ...

In this study, a new and efficient analytical method was developed to determine hexavalent chromium, Cr (VI), in water by flame atomic absorption spectrometry (FAAS). This method consists on the simultaneous selective extraction and preconcentration of Cr (VI) in water by dispersive solid phase ...

Microporous tricobalt tetraoxide, Co3O4, nanoparticles (NPs) clusters have been successfully fabricated using a simple but efficient controlled solution combustion route. Such a synthesis involves combustion reaction of cobalt nitrate with cetyl trimethylammonium bromide (CTAB). The combustion p...

Transition metal selenides are becoming increasingly prominent as promising catalytic materials in energy conversion and storage fields. However, the effect of ternary cobalt nickel selenides (Co-Ni-Ses) on the photovoltaic performance of dye-sensitized solar cells needs to be further explored. ...

The efficiency of oxygen evolution reaction (OER) depends critically on the steric and electronic structures of electrocatalysts. Moreover, a high conductivity of electrocatalysts ensures a fast electron transfer and thus plays a significant role in OER. Therefore, the development of efficient e...

Searching for high-performance and earth-abundant electrocatalysts for oxygen evolution reaction (OER) is of paramount significance for overall water splitting to produce hydrogen. Herein, an advanced class of CoNi selenides containing rich oxygen vacancies, with a hierarchical bundle-like and h...

The Caron process involves the roasting of nickel laterite ore at 750 °C with fuel oil to produce a calcine containing Fe-Ni-Co alloy and other reacted or unreacted host minerals. The leaching of the calcine in the form of a quenched slurry in ammonia/ammonium carbonate solutions at pH ~10 and ...