Hanways focus on: -Pharmaceutical raw materials -Chemical raw materials -Food additives -Flavors and fragrances -Feed additives -Plant extracts -Veterinary raw materials We could supply you: -Best quality -Competitive price
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $10.0
Type:Trading Company
inquiryWhy is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $250.0
Type:Trading Company
inquiry1. "Top 100 innovation-oriented export enterprises Of Hangzhou" honored by Hangzhou government 2. Specialized in the fine chemicals and pharmaceuticals 3. A leading manufacturer and trader of
Cas:202138-50-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
Cas:202138-50-9
Min.Order:1 Metric Ton
FOB Price: $1.0 / 3.0
Type:Manufacturers
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White to off-white crystalline powder Storage:Refrigerato
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $210.0 / 350.0
Type:Trading Company
inquiryHANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $200.0 / 300.0
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:202138-50-9
Min.Order:1
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:202138-50-9
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi
Cas:202138-50-9
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FOB Price: $5.0 / 10.0
Type:Manufacturers
inquiryHigh quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce
Cas:202138-50-9
Min.Order:1 Metric Ton
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Type:Manufacturers
inquiryName:Tenofovir disoproxil fumarate CAS NO: 202138-50-9 Grade:Medical scientific research and export Molecular formula:C19H30N5O10P Molecular weight:635.51 Product Quality 12 years of chemical raw materials Mature operation of the industry
Cas:202138-50-9
Min.Order:25 Kilogram
FOB Price: $1.0 / 2.0
Type:Other
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:202138-50-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:202138-50-9
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:202138-50-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryName: Tenofovir disoproxil fumarate Synonyms:bis({[(1-methylethoxy)carbonyl]oxy}methyl) {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonate (2E)-but-2-enedioate CAS:202138-50-9 MF: C23H34N5O14P Appearance: white powder Storage:Store
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Light –brown powder Storage:Store in sealed containers at co
Cas:202138-50-9
Min.Order:100 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:202138-50-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $155.0
Type:Trading Company
inquiryHangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquirySpecifications: Name: Tenofovir disoproxil fumarate CAS: 202138-50-9 Specification: EP/USP Top quality,best price Appearance:White Powder Storage:Protected from light,stored hermetically and in a dry place Package:1Kg/bag;25Kg/drum or as
Cas:202138-50-9
Min.Order:1 Milligram
FOB Price: $0.1
Type:Other
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:202138-50-9
Min.Order:1 Kilogram
FOB Price: $354.0 / 368.0
Type:Trading Company
inquiryTenofovir disoproxil fumarate CAS:202138-50-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or
Cas:202138-50-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful
Cas:202138-50-9
Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:202138-50-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:202138-50-9
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiry1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi
Cas:202138-50-9
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
In isopropyl alcohol at 50 - 55℃; | 94.4% |
In isopropyl alcohol at 50 - 55℃; for 1h; | 92.2% |
In methanol; water at 0 - 75℃; for 0.5h; Solvent; Temperature; | 90% |
chloromethyl isopropyl carbonate
(2E)-but-2-enedioic acid
tenofovir
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Stage #1: tenofovir With triethylamine In 1-methyl-pyrrolidin-2-one at 63℃; for 0.5h; Stage #2: chloromethyl isopropyl carbonate In 1-methyl-pyrrolidin-2-one at 63℃; for 4h; Stage #3: (2E)-but-2-enedioic acid In isopropyl alcohol at 50℃; for 0.5h; Concentration; | 90% |
Stage #1: chloromethyl isopropyl carbonate; tenofovir With tetrabutylammomium bromide; triethylamine at 50℃; for 3h; Inert atmosphere; Stage #2: (2E)-but-2-enedioic acid In isopropyl alcohol Reagent/catalyst; Temperature; Reflux; | 78.8% |
Stage #1: chloromethyl isopropyl carbonate; tenofovir With tetrabutylammomium bromide; triethylamine In 1-methyl-pyrrolidin-2-one; toluene at 45 - 55℃; for 5h; Stage #2: (2E)-but-2-enedioic acid In isopropyl alcohol at 50 - 55℃; for 2h; | 63.6% |
(2E)-but-2-enedioic acid
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Stage #1: 9-[2-[(R)[[bis[[isopropoxycarbonyl]oxy]methoxy]phosphinyl]methoxy]propyl]adenine orotate With triethylamine In dichloromethane; water at 25℃; Stage #2: (2E)-but-2-enedioic acid In isopropyl alcohol at 0 - 50℃; | 83% |
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: sodium hydroxide / N,N-dimethyl-formamide / 120 °C 2.1: magnesium 2-methylpropan-2-olate / 1-methyl-pyrrolidin-2-one / 70 - 74 °C 3.1: chloro-trimethyl-silane; sodium bromide / 1-methyl-pyrrolidin-2-one / 0 - 75 °C 4.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C 4.2: 5.5 h / 45 - 50 °C 5.1: isopropyl alcohol / 2 h / 50 °C View Scheme | |
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 100 - 120 °C / Inert atmosphere 1.2: 8 h / 120 °C 2.1: magnesium 2-methylpropan-2-olate / N,N-dimethyl-formamide; water / 44 h / -15 - 20 °C / Inert atmosphere 3.1: hydrogenchloride / water / 0.5 h / 140 °C / Microwave irradiation 4.1: triethylamine / 1-methyl-pyrrolidin-2-one / 1 h / 45 °C / Inert atmosphere 4.2: 5 h / 60 °C 5.1: cyclohexane / 0.17 h / 60 °C View Scheme | |
Multi-step reaction with 5 steps 1.1: sodium carbonate / N,N-dimethyl-formamide / 6 h / 95 °C 2.1: lithium tert-butoxide / N,N-dimethyl-formamide / 2 h / 0 - 20 °C 2.2: 0 °C 3.1: hydrogen bromide / 8 h / 80 °C 4.1: triethylamine; benzyltriethylammonium bromide / N,N-dimethyl-formamide / 4 h / 60 °C 5.1: isopropyl alcohol / 2.5 h / 60 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydroxide / N,N-dimethyl-formamide / 0.33 h / 20 °C 1.2: 24.5 h / 120 °C 2.1: lithium tert-butoxide / N,N-dimethyl-formamide / 30 - 35 °C 3.1: trimethylsilyl bromide / acetonitrile / 5 h / Reflux 4.1: triethylamine; tetrabutylammomium bromide / 1-methyl-pyrrolidin-2-one; toluene / 5 h / 45 - 55 °C 4.2: 2 h / 50 - 55 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydroxide / N,N-dimethyl-formamide / 0.33 h / 20 °C 1.2: 24.5 h / 120 °C 2.1: magnesium 2-methylpropan-2-olate; calcium hydride / N,N-dimethyl-formamide / 30 - 35 °C 3.1: trimethylsilyl bromide / acetonitrile / 5 h / Reflux 4.1: toluene; 1-methyl-pyrrolidin-2-one / 60 °C 4.2: 5 h / 45 - 55 °C 4.3: 2 h / 50 - 55 °C View Scheme |
(R)-9-(2-hydroxypropyl)adenine
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: magnesium 2-methylpropan-2-olate / 1-methyl-pyrrolidin-2-one / 70 - 74 °C 2.1: chloro-trimethyl-silane; sodium bromide / 1-methyl-pyrrolidin-2-one / 0 - 75 °C 3.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C 3.2: 5.5 h / 45 - 50 °C 4.1: isopropyl alcohol / 2 h / 50 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: magnesium 2-methylpropan-2-olate / toluene; 1-methyl-pyrrolidin-2-one / 6 h / 25 - 75 °C 1.2: 1 h 1.3: 90 - 95 °C 2.1: toluene / 20 - 110 °C 3.1: chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide / 1-Methylpyrrolidine / 50 - 55 °C 3.2: 5 h / 50 - 55 °C 4.1: isopropyl alcohol / 50 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 35 °C 1.2: 2 h / 25 - 30 °C 1.3: 5 h / 25 - 75 °C 2.1: hydrogen bromide / water / 5 h / 90 - 95 °C 2.2: 4 h / 0 - 30 °C / pH 2.5 - 3 3.1: triethylamine / cyclohexane / 2 h / 80 - 85 °C 3.2: 4 h / 50 - 55 °C 4.1: isopropyl alcohol / 0.33 h / 50 - 55 °C 4.2: 5.5 h / 0 - 55 °C View Scheme |
tenofovir
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C 1.2: 5.5 h / 45 - 50 °C 2.1: isopropyl alcohol / 2 h / 50 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: toluene / 20 - 110 °C 2.1: chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide / 1-Methylpyrrolidine / 50 - 55 °C 2.2: 5 h / 50 - 55 °C 3.1: isopropyl alcohol / 50 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: triethylamine / 1-methyl-pyrrolidin-2-one / 1 h / 45 °C / Inert atmosphere 1.2: 5 h / 60 °C 2.1: cyclohexane / 0.17 h / 60 °C View Scheme |
(R)-diethyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: chloro-trimethyl-silane; sodium bromide / 1-methyl-pyrrolidin-2-one / 0 - 75 °C 2.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C 2.2: 5.5 h / 45 - 50 °C 3.1: isopropyl alcohol / 2 h / 50 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: hydrogen bromide / water / 5 h / 90 - 95 °C 1.2: 4 h / 0 - 30 °C / pH 2.5 - 3 2.1: triethylamine / cyclohexane / 2 h / 80 - 85 °C 2.2: 4 h / 50 - 55 °C 3.1: isopropyl alcohol / 0.33 h / 50 - 55 °C 3.2: 5.5 h / 0 - 55 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: hydrogen bromide / water / 2 h / 90 - 95 °C 1.2: 5 h / 0 - 30 °C / pH 2.5 2.1: triethylamine / cyclohexane / 2 h / 20 - 85 °C 2.2: 4 h / 25 - 55 °C 2.3: pH 6.5 - 7.5 3.1: isopropyl alcohol / 0.33 h / 50 - 55 °C 3.2: 5.5 h / 0 - 55 °C View Scheme |
tenofovir disoproxil chloromethyl-isopropyl carbonate
(2E)-but-2-enedioic acid
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
In isopropyl alcohol at 50℃; |
chloromethyl isopropyl carbonate
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide / 1-Methylpyrrolidine / 50 - 55 °C 1.2: 5 h / 50 - 55 °C 2.1: isopropyl alcohol / 50 °C View Scheme |
bis(2-propyl) (R)-9-(2-phosphonomethoxypropyl)adenine
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydrogenchloride / water / 0.5 h / 140 °C / Microwave irradiation 2.1: triethylamine / 1-methyl-pyrrolidin-2-one / 1 h / 45 °C / Inert atmosphere 2.2: 5 h / 60 °C 3.1: cyclohexane / 0.17 h / 60 °C View Scheme |
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
With phosphoric acid In water; isopropyl alcohol at 60℃; for 0.5h; | 90% |
With phosphoric acid In water; isopropyl alcohol at 60℃; for 0.5h; | 90% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 80℃; for 6h; | 11.24% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 80℃; for 1h; | 8.1% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 80℃; for 13h; | 5.67% |
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
In Methyl isobutyl carbinol at 22 - 60℃; for 48h; Product distribution / selectivity; | |
In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 5 - 60℃; under 150.015 Torr; Product distribution / selectivity; | |
In tetrahydrofuran; nitrobenzene at 5 - 60℃; under 150.015 Torr; Product distribution / selectivity; |
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In water; ethyl acetate at 20℃; for 0.666667h; pH=7; | 35 g |
With sodium hydrogencarbonate In Isopropyl acetate; water at 22℃; for 0.5h; Reagent/catalyst; |
25,26,27,28-terahydroxycalix[4]arene-5,11,7,23-tetrasulfonic acid
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
In dimethylsulfoxide-d6 |
tenofovir disoproxyl fumarate
Conditions | Yield |
---|---|
In dimethylsulfoxide-d6 |
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