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HANWAYS CHEMPHARM CO.,LIMITED

Hanways focus on: -Pharmaceutical raw materials -Chemical raw materials -Food additives -Flavors and fragrances -Feed additives -Plant extracts -Veterinary raw materials We could supply you: -Best quality -Competitive price

Tenofovir Disoproxil Fumarate 202138-50-9

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

Best Price for Tenofovir disoproxil fumarate/TDF powder CAS 202138-50-9

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $250.0

Type:Trading Company

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Afine Chemicals Limited

1. "Top 100 innovation-oriented export enterprises Of Hangzhou" honored by Hangzhou government 2. Specialized in the fine chemicals and pharmaceuticals 3. A leading manufacturer and trader of

Supply Tenofovir disoproxil fumarate high quality Hot sale 99.0% Tenofovir disoproxil fumarate price market

Cas:202138-50-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Tenofovir disoproxil fumarate Manufacturer/High quality/Best price/In stock

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Tenofovir disoproxil fumarate CAS NO.202138-50-9

Cas:202138-50-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White to off-white crystalline powder Storage:Refrigerato

Factory supply Tenofovir disoproxil fumarate CAS 202138-50-9 with good quality

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $210.0 / 350.0

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

Tenofovir disoproxil fumarate manufacture factory

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Tenofovir disoproxil fumarate 202138-50-9 ISO Producer

Cas:202138-50-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

Tenofovir disoproxil fumarate

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

Tenofovir disoproxil fumarate

Cas:202138-50-9

Min.Order:0

Negotiable

Type:Trading Company

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Chemwill Asia Co., Ltd.

Tenofovir disoproxil fumarate -- CHemwill

Cas:202138-50-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:Tenofovir disoproxil fumarate CAS NO: 202138-50-9 Grade:Medical scientific research and export Molecular formula:C19H30N5O10P Molecular weight:635.51 Product Quality 12 years of chemical raw materials Mature operation of the industry

Tenofovir disoproxil fumarate/cas:202138-50-9/Raw material spot

Cas:202138-50-9

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Tenofovir disoproxil fumarate

Cas:202138-50-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Tenofovir Disoproxil CAS 202138-50-9

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 202138-50-9 with best quality

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

hot sale Tenofovir disoproxil fumarate for sale

Cas:202138-50-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Tenofovir disoproxil fumarate/ LIDE PHARMA- Factory supply / Best price

Cas:202138-50-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Name: Tenofovir disoproxil fumarate Synonyms:bis({[(1-methylethoxy)carbonyl]oxy}methyl) {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonate (2E)-but-2-enedioate CAS:202138-50-9 MF: C23H34N5O14P Appearance: white powder Storage:Store

Tenofovir disoproxil fumarate CAS:202138-50-9

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Light –brown powder Storage:Store in sealed containers at co

CAS 202138-50-9 Tenofovir disoproxil fumarate

Cas:202138-50-9

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Tenofovir disoproxil fumarate 202138-50-9

Cas:202138-50-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

High Quality 99% Tenofovir disoproxil fumarate raw powder Tenofovir disoproxil fumarate

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $155.0

Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac

Tenofovir disoproxil fumarate

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Hangzhou Maytime Bio-Tech Co.,Ltd.

Specifications: Name: Tenofovir disoproxil fumarate CAS: 202138-50-9 Specification: EP/USP Top quality,best price Appearance:White Powder Storage:Protected from light,stored hermetically and in a dry place Package:1Kg/bag;25Kg/drum or as

High-Purity USP37 Tenofovir Disoproxil Fumarate/TDF Cas no.202138-50-9

Cas:202138-50-9

Min.Order:1 Milligram

FOB Price: $0.1

Type:Other

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Reverse transcriptase inhibitor, Tenofovir disoproxil fumarate CAS:202138-50-9

Cas:202138-50-9

Min.Order:1 Kilogram

FOB Price: $354.0 / 368.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Tenofovir disoproxil fumarate CAS:202138-50-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

Tenofovir disoproxil fumarate CAS:202138-50-9

Cas:202138-50-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful

Factory stock, favorable price CAS 202138-50-9

Cas:202138-50-9

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Tenofovir disoproxil fumarate

Cas:202138-50-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Tenofovir disoproxil fumarate manufacturer with low price

Cas:202138-50-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi

Tenofovir disoproxil fumarate 98%

Cas:202138-50-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Synthetic route

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

tenofovir disoproxil

tenofovir disoproxil

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
In isopropyl alcohol at 50 - 55℃;94.4%
In isopropyl alcohol at 50 - 55℃; for 1h;92.2%
In methanol; water at 0 - 75℃; for 0.5h; Solvent; Temperature;90%
chloromethyl isopropyl carbonate
35180-01-9

chloromethyl isopropyl carbonate

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

tenofovir
147127-20-6

tenofovir

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
Stage #1: tenofovir With triethylamine In 1-methyl-pyrrolidin-2-one at 63℃; for 0.5h;
Stage #2: chloromethyl isopropyl carbonate In 1-methyl-pyrrolidin-2-one at 63℃; for 4h;
Stage #3: (2E)-but-2-enedioic acid In isopropyl alcohol at 50℃; for 0.5h; Concentration;
90%
Stage #1: chloromethyl isopropyl carbonate; tenofovir With tetrabutylammomium bromide; triethylamine at 50℃; for 3h; Inert atmosphere;
Stage #2: (2E)-but-2-enedioic acid In isopropyl alcohol Reagent/catalyst; Temperature; Reflux;
78.8%
Stage #1: chloromethyl isopropyl carbonate; tenofovir With tetrabutylammomium bromide; triethylamine In 1-methyl-pyrrolidin-2-one; toluene at 45 - 55℃; for 5h;
Stage #2: (2E)-but-2-enedioic acid In isopropyl alcohol at 50 - 55℃; for 2h;
63.6%
9-[2-[(R)[[bis[[isopropoxycarbonyl]oxy]methoxy]phosphinyl]methoxy]propyl]adenine orotate

9-[2-[(R)[[bis[[isopropoxycarbonyl]oxy]methoxy]phosphinyl]methoxy]propyl]adenine orotate

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
Stage #1: 9-[2-[(R)[[bis[[isopropoxycarbonyl]oxy]methoxy]phosphinyl]methoxy]propyl]adenine orotate With triethylamine In dichloromethane; water at 25℃;
Stage #2: (2E)-but-2-enedioic acid In isopropyl alcohol at 0 - 50℃;
83%
Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sodium hydroxide / N,N-dimethyl-formamide / 120 °C
2.1: magnesium 2-methylpropan-2-olate / 1-methyl-pyrrolidin-2-one / 70 - 74 °C
3.1: chloro-trimethyl-silane; sodium bromide / 1-methyl-pyrrolidin-2-one / 0 - 75 °C
4.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C
4.2: 5.5 h / 45 - 50 °C
5.1: isopropyl alcohol / 2 h / 50 °C
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 100 - 120 °C / Inert atmosphere
1.2: 8 h / 120 °C
2.1: magnesium 2-methylpropan-2-olate / N,N-dimethyl-formamide; water / 44 h / -15 - 20 °C / Inert atmosphere
3.1: hydrogenchloride / water / 0.5 h / 140 °C / Microwave irradiation
4.1: triethylamine / 1-methyl-pyrrolidin-2-one / 1 h / 45 °C / Inert atmosphere
4.2: 5 h / 60 °C
5.1: cyclohexane / 0.17 h / 60 °C
View Scheme
Multi-step reaction with 5 steps
1.1: sodium carbonate / N,N-dimethyl-formamide / 6 h / 95 °C
2.1: lithium tert-butoxide / N,N-dimethyl-formamide / 2 h / 0 - 20 °C
2.2: 0 °C
3.1: hydrogen bromide / 8 h / 80 °C
4.1: triethylamine; benzyltriethylammonium bromide / N,N-dimethyl-formamide / 4 h / 60 °C
5.1: isopropyl alcohol / 2.5 h / 60 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydroxide / N,N-dimethyl-formamide / 0.33 h / 20 °C
1.2: 24.5 h / 120 °C
2.1: lithium tert-butoxide / N,N-dimethyl-formamide / 30 - 35 °C
3.1: trimethylsilyl bromide / acetonitrile / 5 h / Reflux
4.1: triethylamine; tetrabutylammomium bromide / 1-methyl-pyrrolidin-2-one; toluene / 5 h / 45 - 55 °C
4.2: 2 h / 50 - 55 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydroxide / N,N-dimethyl-formamide / 0.33 h / 20 °C
1.2: 24.5 h / 120 °C
2.1: magnesium 2-methylpropan-2-olate; calcium hydride / N,N-dimethyl-formamide / 30 - 35 °C
3.1: trimethylsilyl bromide / acetonitrile / 5 h / Reflux
4.1: toluene; 1-methyl-pyrrolidin-2-one / 60 °C
4.2: 5 h / 45 - 55 °C
4.3: 2 h / 50 - 55 °C
View Scheme
(R)-9-(2-hydroxypropyl)adenine
14047-28-0

(R)-9-(2-hydroxypropyl)adenine

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: magnesium 2-methylpropan-2-olate / 1-methyl-pyrrolidin-2-one / 70 - 74 °C
2.1: chloro-trimethyl-silane; sodium bromide / 1-methyl-pyrrolidin-2-one / 0 - 75 °C
3.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C
3.2: 5.5 h / 45 - 50 °C
4.1: isopropyl alcohol / 2 h / 50 °C
View Scheme
Multi-step reaction with 4 steps
1.1: magnesium 2-methylpropan-2-olate / toluene; 1-methyl-pyrrolidin-2-one / 6 h / 25 - 75 °C
1.2: 1 h
1.3: 90 - 95 °C
2.1: toluene / 20 - 110 °C
3.1: chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide / 1-Methylpyrrolidine / 50 - 55 °C
3.2: 5 h / 50 - 55 °C
4.1: isopropyl alcohol / 50 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 35 °C
1.2: 2 h / 25 - 30 °C
1.3: 5 h / 25 - 75 °C
2.1: hydrogen bromide / water / 5 h / 90 - 95 °C
2.2: 4 h / 0 - 30 °C / pH 2.5 - 3
3.1: triethylamine / cyclohexane / 2 h / 80 - 85 °C
3.2: 4 h / 50 - 55 °C
4.1: isopropyl alcohol / 0.33 h / 50 - 55 °C
4.2: 5.5 h / 0 - 55 °C
View Scheme
tenofovir
147127-20-6

tenofovir

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C
1.2: 5.5 h / 45 - 50 °C
2.1: isopropyl alcohol / 2 h / 50 °C
View Scheme
Multi-step reaction with 3 steps
1.1: toluene / 20 - 110 °C
2.1: chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide / 1-Methylpyrrolidine / 50 - 55 °C
2.2: 5 h / 50 - 55 °C
3.1: isopropyl alcohol / 50 °C
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine / 1-methyl-pyrrolidin-2-one / 1 h / 45 °C / Inert atmosphere
1.2: 5 h / 60 °C
2.1: cyclohexane / 0.17 h / 60 °C
View Scheme
(R)-diethyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
180587-75-1

(R)-diethyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: chloro-trimethyl-silane; sodium bromide / 1-methyl-pyrrolidin-2-one / 0 - 75 °C
2.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C
2.2: 5.5 h / 45 - 50 °C
3.1: isopropyl alcohol / 2 h / 50 °C
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogen bromide / water / 5 h / 90 - 95 °C
1.2: 4 h / 0 - 30 °C / pH 2.5 - 3
2.1: triethylamine / cyclohexane / 2 h / 80 - 85 °C
2.2: 4 h / 50 - 55 °C
3.1: isopropyl alcohol / 0.33 h / 50 - 55 °C
3.2: 5.5 h / 0 - 55 °C
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogen bromide / water / 2 h / 90 - 95 °C
1.2: 5 h / 0 - 30 °C / pH 2.5
2.1: triethylamine / cyclohexane / 2 h / 20 - 85 °C
2.2: 4 h / 25 - 55 °C
2.3: pH 6.5 - 7.5
3.1: isopropyl alcohol / 0.33 h / 50 - 55 °C
3.2: 5.5 h / 0 - 55 °C
View Scheme
tenofovir disoproxil chloromethyl-isopropyl carbonate
1215085-38-3

tenofovir disoproxil chloromethyl-isopropyl carbonate

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
In isopropyl alcohol at 50℃;
chloromethyl isopropyl carbonate
35180-01-9

chloromethyl isopropyl carbonate

(x)C6H15N*C9H14N5O4P

(x)C6H15N*C9H14N5O4P

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide / 1-Methylpyrrolidine / 50 - 55 °C
1.2: 5 h / 50 - 55 °C
2.1: isopropyl alcohol / 50 °C
View Scheme
bis(2-propyl) (R)-9-(2-phosphonomethoxypropyl)adenine
160616-04-6

bis(2-propyl) (R)-9-(2-phosphonomethoxypropyl)adenine

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: hydrogenchloride / water / 0.5 h / 140 °C / Microwave irradiation
2.1: triethylamine / 1-methyl-pyrrolidin-2-one / 1 h / 45 °C / Inert atmosphere
2.2: 5 h / 60 °C
3.1: cyclohexane / 0.17 h / 60 °C
View Scheme
tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid

({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid

Conditions
ConditionsYield
With phosphoric acid In water; isopropyl alcohol at 60℃; for 0.5h;90%
With phosphoric acid In water; isopropyl alcohol at 60℃; for 0.5h;90%
formaldehyd
50-00-0

formaldehyd

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

C59H90N15O30P3

C59H90N15O30P3

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 6h;11.24%
formaldehyd
50-00-0

formaldehyd

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

C39H60N10O20P2

C39H60N10O20P2

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 1h;8.1%
formaldehyd
50-00-0

formaldehyd

Tenofovir mono-POC

Tenofovir mono-POC

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

C34H52N10O17P2

C34H52N10O17P2

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 13h;5.67%
tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

9-[(R)-2-[[bis[[ (isopropoxycarbonyl)oxy]methoxy]phosphinyl]-methoxy]propyl]adenine fumarate Tenofovir disoproxil fumarate

9-[(R)-2-[[bis[[ (isopropoxycarbonyl)oxy]methoxy]phosphinyl]-methoxy]propyl]adenine fumarate Tenofovir disoproxil fumarate

Conditions
ConditionsYield
In Methyl isobutyl carbinol at 22 - 60℃; for 48h; Product distribution / selectivity;
In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 5 - 60℃; under 150.015 Torr; Product distribution / selectivity;
In tetrahydrofuran; nitrobenzene at 5 - 60℃; under 150.015 Torr; Product distribution / selectivity;
tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

tenofovir disoproxil

tenofovir disoproxil

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; ethyl acetate at 20℃; for 0.666667h; pH=7;35 g
With sodium hydrogencarbonate In Isopropyl acetate; water at 22℃; for 0.5h; Reagent/catalyst;
25,26,27,28-terahydroxycalix[4]arene-5,11,7,23-tetrasulfonic acid
386768-13-4, 189397-70-4, 112269-92-8

25,26,27,28-terahydroxycalix[4]arene-5,11,7,23-tetrasulfonic acid

tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

C19H30N5O10P*C28H24O16S4

C19H30N5O10P*C28H24O16S4

Conditions
ConditionsYield
In dimethylsulfoxide-d6
tenofovir disoproxyl fumarate
202138-50-9

tenofovir disoproxyl fumarate

para-sulphonato-thiacalix[4]arene

para-sulphonato-thiacalix[4]arene

C19H30N5O10P*C24H16O16S8

C19H30N5O10P*C24H16O16S8

Conditions
ConditionsYield
In dimethylsulfoxide-d6
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