The direct polarographic determination of dibutyl phthalate in propellant compositions containing nitroglycerine is not readily practicable by normal polarography because of the marked interference of the nitroglycerine which gives polarographic steps preceding those of the dibutyl phthalate, ma...

Solubility and acid–base properties of S-carboxymethyl-l-cysteine (carbocysteine, ccys) in NaClaq and tetramethylammonium chloride, (CH3)4NClaq, at t = 25 °C and at different ionic strengths were investigated. Solubility was studied at 1.0 ≤ I (mol L−1) ≤ 5.0 for NaClaq and 1.0 ≤ I (mol L−1...

We have reported that the conversion ratio of tryptophan to niacin increased with increasing dietary concentration of di(2-ethylhexyl)phthalate (DEHP); the conversion ratio was about 2.0% in the control rat, which increased by about 30% in the rat fed with 3.0% DEHP diet. In this study, we inves...

Pyrograms of three fulvic acids (FAs) of different origins and the corresponding pyrograms obtained by reactive pyrolysis with tetramethylammonium hydroxide (TMAH) are compared. This procedure introduces both striking qualitative and quantitative changes in the pyrolytic patterns of the FAs, whi...

The structures of two acid tetraalkylammonium phthalates were determined with X-rays. Tetraethylammonium hydrogen phthalate (C16H25NO4) (1) has space group P21/c with a= 10.456(8) Å, b=9.984 (6) Å c=15.630 (5) Å,β /1=97.13 (3)°, Z=4. Tetrabutylammonium hydrogen phthalate (C24H41N04) (2) has sp...

Thermally assisted hydrolysis and methylation (THM) in the presence of tetramethylammonium hydroxide (TMAH) was applied to the analysis of red dyes based on the 9,10-anthracenedione skeleton (anthraquinone), namely alizarin, quinizarin, purpurin, carminic acid, and the blue pigment indigo. Aliza...

Tetramethylammonium acetate (TMAAc) was found to be a selective reagent for the methylation of free acids. It was shown that free fatty acids and their salts could be fully derivatised by TMAAc in the presence of esterified fatty acids. This was performed on extracts containing mixtures of wood ...

The fluorodenitration of several nitroaromatics with tetramethylammonium salts has been found to be dependent on the basicity of the fluorinating species. Tetramethylammonium fluoride is highly basic and is capable of inducing H-D exchange in 1,3-dinitrobenzene, as well as deprotonating N,N-dime...

A series of amine-alkyl derivatives of 5-arylidenehydantoin 3–21 was evaluated for their ability to improve antibiotic effectiveness in two strains of Gram-negative Enterobacter aerogenes: the reference strain (ATCC-13048) and the chloramphenicol-resistant derivative over-producing the AcrAB-To...

A series of 5-(4-substituted piperazin-1-yl)quinolin-2(1H)-one derivatives (4a-4w) has been designed as chitin synthase inhibitors and antifungal agents. The designed compounds were obtained by an environmentally benign route in four steps starting from 5-amino-3,4-dihydroquinolin-2(1H)-one whic...

The enantioselective electrophilic fluorination of α-aryl-tetralones is promoted by cinchonine/selectfluor combinations. This strategy allows a facile synthesis of the corresponding 2-fluoro-2-aryl-1-tetralones with excellent yields (up to >98%) and moderate to good enantioselectivity (up to74%).

The design and synthesis of a series of thirty-two halogenated 1-tetralone or 6-amino-1-tetralone chalcone derivatives was achieved by the Claisen-Schmidt condensation reaction and were evaluated for their inhibitory effects against ROS production in LPS-stimulated RAW 264.7 macrophages. It was ...

The reaction of N-unprotected methylesters of phenylglycine derivatives (1a–1f) with electron-rich internal alkynes (2a–2e), catalyzed by [Ru(cymene)Cl2]2 (10%), gives the corresponding 3,4-disubstituted isoquinoline-1-carboxylates 3 through CH/NH oxidative coupling. The CH bond activation ste...

ABSTRACTThree novel thiophene based monomers, 2,5-di-2,3-dihydrothieno[3,4-b][1,4]dioxin-5-ylthienyl derivatives, 1-{4-[(2,5-Di-2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl-3-thienyl) methoxy] phenyl}-2-phenyldiazene) (ETEAz), 4-[(2,5-Di-2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl-3-thienyl) methoxy]-2...

Dipeptidyl (acyloxy)methyl ketones (AOMKs) have been identified as mechanism-based inhibitors of certain cysteine proteases. These compounds are also inhibitors of the integral membrane proteins Rce1p and Ste24p, which are proteases that independently mediate a cleavage step associated with the ...

Recently we synthesized new drugs, diazenecarboxamides (shortly diazenes), that were cytotoxic for several tumour cell lines. Because the solubility and biological activity of these drugs was relatively low, new compounds have been synthesized. In the present study we examined the cytotoxic effe...

Several fillers containing various percentages of talc were incorporated at 40% loading, and at 20% in combination with 20% of a brominated flame retardant system in a PP-PE copolymer. Fire resistance and mechanical properties were studied. Ignition time at dripping test, UL 94 behaviour, and te...

Highly selective, practical, and efficient protocols for the preparation of 4(5)-aryl-1H-imidazoles 2, 2,4(5)-diaryl-1H-imidazoles 3, and 4,5-diaryl-1H-imidazoles 1 are described. A key step of these protocols is the regioselective synthesis of 5-aryl-1-benzyl-1H-imidazoles 9 by Pd-catalyzed dir...

Hydroxy-4-methoxytricyclo[7.3.1.02,7]trideca-2,4,6-trien-8-one was synthesized from 1-benzyloxy-4-bromo-2-methoxybenzene in six steps comprising Corey–Chaykovsky epoxidation and Friedel–Crafts intramolecular cyclization. The crystal structure of the benzyl-protected derivative of the target co...

N-Benzyl substitution of phenethylamine 5-HT2A receptor agonists has dramatic effects on binding affinity, receptor selectivity and agonist activity. In this paper we examine how affinity for the 5-HT2A/2C receptors are influenced by N-benzyl substitution of 4-bromo-2,5-dimethoxyphenethylamine d...