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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Chloronicotinic acid Manufacturer/High quality/Best price/In stock

Cas:10177-29-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Chloronicotinic Acid supplier in China

Cas:10177-29-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ---------------------------------------------------------------------------------------------

High purity Various Specifications 4-chloronicotinic acid CAS:10177-29-4

Cas:10177-29-4

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-Chloronicotinic Acid

Cas:10177-29-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:1 Gram

FOB Price: $11.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

4-Chloronicotinic acid Basic information Product Name: 4-Chloronicotinic acid Synonyms: 4-CHLOROPYRIDINE-3-CARBOXYLIC ACID;4-CHLORO-3-PYRIDINECARBOXYLIC ACID;4-CHLORONICOTINIC ACID;IFLAB

high purity of 4-chloronicotinic acid

Cas:10177-29-4

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 10177-29-4 with fast shipping

Cas:10177-29-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White powder Storage:Inert atmosphere,2-8°C Package:25kg/drum Application:4-Chloronicotinic Acid is a building block used in a synthesis of benzocanthinones via tributyltin hydride radical induced cyclization. It is also used in a synthe

4-chloronicotinic acid factory price

Cas:10177-29-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry plac

CAS NO. 10177-29-4 4-Chloronicotinic acid with best price

Cas:10177-29-4

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-Chloronicotinic acid 10177-29-4

Cas:10177-29-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

4-Chloronicotinic acid,99%

Cas:10177-29-4

Min.Order:1 Kilogram

FOB Price: $68.0 / 75.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

4-Chloronicotinic acid CAS:10177-29-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

4-Chloronicotinic acid CAS:10177-29-4

Cas:10177-29-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

4-Chloronicotinic acid/ LIDE PHARMA- Factory supply / Best price

Cas:10177-29-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS

China Largest Factory Manufacturer sales 4-Chloronicotinic acid CAS 10177-29-4

Cas:10177-29-4

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Chloronicotinic Acid

Cas:10177-29-4

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Se

4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

4-Chloronicotinic acid /High quality/Best price

Cas:10177-29-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-chloronicotinic acid

Cas:10177-29-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Chloropyridine-3-carboxylic acid

Cas:10177-29-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4-chloropyridine-3-carboxylic acid

Cas:10177-29-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:1 Gram

Negotiable

Type:Other

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

4-Chloronicotinic acid /High quality/Best price

Cas:10177-29-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 4-Chloronicotinic Acid

Cas:10177-29-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-Chloronicotinic acid

Cas:10177-29-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Name: 4-chloronicotinic acid Synonyms: 4-CHLOROPYRIDINE-3-CARBOXYLIC ACID;4-CHLORO-3-PYRIDINECARBOXYLIC ACID;4-CHLORONICOTINIC ACID;IFLAB-BB F1926-0029;4-Chloro-3-pyridinecarboxylic; Cas No.:

4-chloronicotinic acid

Cas:10177-29-4

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...)

4-Chloronicotinic acid CAS NO.: 10177-29-4

Cas:10177-29-4

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

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Synthetic route

4-Chloropyridine
626-61-9

4-Chloropyridine

carbon dioxide
124-38-9

carbon dioxide

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran 1.) -78 deg C, 20 min, 2.) 18 h;96%
Stage #1: 4-Chloropyridine With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; Inert atmosphere;
Stage #2: carbon dioxide In tetrahydrofuran; hexane
80%
Stage #1: 4-Chloropyridine With lithium diisopropyl amide In tetrahydrofuran; hexanes at -78℃; Inert atmosphere;
Stage #2: carbon dioxide In tetrahydrofuran; hexanes
Stage #1: 4-Chloropyridine With lithium diisopropyl amide In tetrahydrofuran at -78℃;
Stage #2: carbon dioxide In tetrahydrofuran at -78 - 20℃; Product distribution / selectivity;
Stage #1: 4-Chloropyridine With lithium diisopropyl amide In tetrahydrofuran at -78℃;
Stage #2: carbon dioxide In tetrahydrofuran at -78℃;
lithium; 4-chloro-nicotinate

lithium; 4-chloro-nicotinate

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
With Amberlyst(R) IR-200 In methanol at 20℃; for 0.25h;75%
4-chloro-3-methylpyridine
1681-36-3

4-chloro-3-methylpyridine

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
With potassium permanganate In water at 80 - 90℃; for 4h;65%
carbon dioxide
124-38-9

carbon dioxide

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
Stage #1: 4-Chloropyridine With lithium diisopropyl amide In tetrahydrofuran; hexanes at -78℃; for 1h;
Stage #2: carbon dioxide In tetrahydrofuran; hexanes at -78 - 20℃;
61%
Stage #1: 4-Chloropyridine With lithium diisopropyl amide In tetrahydrofuran; hexanes at -78℃; for 1h;
Stage #2: carbon dioxide In tetrahydrofuran; hexanes
61%
carbon dioxide
124-38-9

carbon dioxide

4-chlorpyridine hydrochloride
7379-35-3

4-chlorpyridine hydrochloride

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
Stage #1: 4-chlorpyridine hydrochloride With sodium carbonate In water
Stage #2: With n-butyllithium; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #3: carbon dioxide In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
57%
4-chloronicotinaldehyde
114077-82-6

4-chloronicotinaldehyde

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
With potassium permanganate In water for 3h; Heating / reflux;56%
With potassium permanganate In water; acetonitrile
4-hydroxynicotinic acid
609-70-1

4-hydroxynicotinic acid

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
With thionyl chloride anschliessende Hydrolyse;
Nicotinic acid N-oxide
2398-81-4

Nicotinic acid N-oxide

phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

A

2-chloronicotinic acid
2942-59-8

2-chloronicotinic acid

B

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

nicotinic acid-1-oxide

nicotinic acid-1-oxide

A

2-chloronicotinic acid
2942-59-8

2-chloronicotinic acid

B

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
With phosphorus pentachloride; trichlorophosphate
nicotinic acid
59-67-6

nicotinic acid

potassium

potassium

A

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

B

Nα-Fmoc-Nim-tert-butyloxycarbonyl-L-tryptophan 4-hydroxymethylphenoxy resin

Nα-Fmoc-Nim-tert-butyloxycarbonyl-L-tryptophan 4-hydroxymethylphenoxy resin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: BuLi; 2,2,6,6-tetramethylpiperidine / tetrahydrofuran; hexane / 0.67 h / -75 - -55 °C
1.2: 79 percent / hexachloroethane / tetrahydrofuran; hexane / -55 - 20 °C
2.1: 75 percent / Amberlyst(R) IR-200 / methanol / 0.25 h / 20 °C
View Scheme
3-picoline-N-oxide
1003-73-2

3-picoline-N-oxide

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 51 percent / HNO3, H2SO4 / 2 h
2: 97 percent / HCl, PCl3 / CHCl3 / 0.33 h / Heating
3: 65 percent / KMnO4 / H2O / 4 h / 80 - 90 °C
View Scheme
3-methyl-4-nitropyridine N-oxide
1074-98-2

3-methyl-4-nitropyridine N-oxide

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 97 percent / HCl, PCl3 / CHCl3 / 0.33 h / Heating
2: 65 percent / KMnO4 / H2O / 4 h / 80 - 90 °C
View Scheme
nicotinic acid
59-67-6

nicotinic acid

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
Stage #1: nicotinic acid With n-butyllithium; 2,2,6,6-tetramethylpiperidinyl-lithium In tetrahydrofuran at -78℃;
Stage #2: With hexachloroethane In tetrahydrofuran at -78 - 20℃; Product distribution / selectivity;
4-chlorpyridine hydrochloride
7379-35-3

4-chlorpyridine hydrochloride

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide
2: lithium diisopropyl amide / hexane; tetrahydrofuran / -78 °C / Inert atmosphere
View Scheme
2,5-dichlorbenzenethiol
5858-18-4

2,5-dichlorbenzenethiol

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

C12H7Cl2NO2S*ClH

C12H7Cl2NO2S*ClH

Conditions
ConditionsYield
In acetone for 3h; Heating / reflux;100%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

methyl 4-chloronicotinate
63592-85-8

methyl 4-chloronicotinate

Conditions
ConditionsYield
With oxalyl dichloride In dichloromethane at 20℃; for 3h; Inert atmosphere;99.16%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-chloronicotinoyl chloride
100791-00-2

4-chloronicotinoyl chloride

Conditions
ConditionsYield
With thionyl chloride at 80℃; for 1.5h;98.5%
With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 20℃; for 3h;
With thionyl chloride for 1.5h; Reflux;
methanol
67-56-1

methanol

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

methyl 4-chloronicotinate
63592-85-8

methyl 4-chloronicotinate

Conditions
ConditionsYield
Stage #1: 4-chloronicotinic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 0.75h;
Stage #2: methanol In dichloromethane at 0℃;
98%
Stage #1: 4-chloronicotinic acid With thionyl chloride Reflux;
Stage #2: methanol In dichloromethane at 0℃; Alkaline conditions;
83%
Stage #1: 4-chloronicotinic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 20℃; for 3h;
Stage #2: methanol In dichloromethane; N,N-dimethyl-formamide for 0.5h;
50%
Stage #1: 4-chloronicotinic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; for 2h;
Stage #2: methanol In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;
Stage #1: 4-chloronicotinic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 0 - 20℃; for 2h;
Stage #2: methanol In dichloromethane at 0 - 20℃; for 0.5h;
5-chloro-2-methylthiophenol
18858-06-5

5-chloro-2-methylthiophenol

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-[(2-methyl-5-chlorophenyl)thio]pyridine-3-carboxylic acid hydrochloride

4-[(2-methyl-5-chlorophenyl)thio]pyridine-3-carboxylic acid hydrochloride

Conditions
ConditionsYield
In acetone for 3h; Substitution; Heating;95%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

benzyl alcohol
100-51-6

benzyl alcohol

benzyl-4-chloropyridin-3-yl carbamate
1033418-69-7

benzyl-4-chloropyridin-3-yl carbamate

Conditions
ConditionsYield
With diphenyl phosphoryl azide; triethylamine In acetonitrile at 120℃;95%
ethanol
64-17-5

ethanol

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

ethyl 4-chloronicotinate
37831-62-2

ethyl 4-chloronicotinate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0℃; for 4h;94%
Stage #1: 4-chloronicotinic acid With thionyl chloride for 1.5h; Heating / reflux;
Stage #2: ethanol With N-ethyl-N,N-diisopropylamine In ethanol at 0 - 20℃; for 4h;
94%
Stage #1: 4-chloronicotinic acid With thionyl chloride at 80℃; for 1.5h;
Stage #2: ethanol With N-ethyl-N,N-diisopropylamine at 0 - 20℃; for 4h;
74.7%
2-nitro-5-chlorothiophenol
14371-79-0

2-nitro-5-chlorothiophenol

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-(2-nitro-5-chlorothiophenoxy)pyridine-3-carboxylic acid hydrochloride

4-(2-nitro-5-chlorothiophenoxy)pyridine-3-carboxylic acid hydrochloride

Conditions
ConditionsYield
In acetone for 1h; Heating;92%
3-chlorophenylthiol
2037-31-2

3-chlorophenylthiol

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

C12H8ClNO2S*ClH

C12H8ClNO2S*ClH

Conditions
ConditionsYield
In acetone for 3h; Heating / reflux; Under N2;91%
N-(3,4,5-trimethoxybenzyl)cyclopropanamine
14471-17-1

N-(3,4,5-trimethoxybenzyl)cyclopropanamine

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-chloro-N-cyclopropyl-N-(3,4,5-trimethoxybenzyl)nicotinamide

4-chloro-N-cyclopropyl-N-(3,4,5-trimethoxybenzyl)nicotinamide

Conditions
ConditionsYield
Stage #1: 4-chloronicotinic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; for 1.5h;
Stage #2: N-(3,4,5-trimethoxybenzyl)cyclopropanamine With triethylamine In dichloromethane at 0℃; for 1h;
91%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

methyl 2,3-deoxy-3-(azido)-4,6-O-isopropylidene-β-D-glucosamine
334002-51-6

methyl 2,3-deoxy-3-(azido)-4,6-O-isopropylidene-β-D-glucosamine

N-((4aR,6R,7R,8R,8aS)-8-Azido-6-methoxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-4-chloro-nicotinamide
334002-76-5

N-((4aR,6R,7R,8R,8aS)-8-Azido-6-methoxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-4-chloro-nicotinamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃;89%
With dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃;33%
2-bromo-5-fluorobenzene-1-thiol
55389-14-5

2-bromo-5-fluorobenzene-1-thiol

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

C12H7BrFNO2S*ClH

C12H7BrFNO2S*ClH

Conditions
ConditionsYield
In acetone for 3h; Heating / reflux; Under N2;87%
2-isopropyliodobenzene
19099-54-8

2-isopropyliodobenzene

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

bicyclo[2.2.1]hepta-2,5-diene
121-46-0

bicyclo[2.2.1]hepta-2,5-diene

7-isopropylbenzo[f]isoquinoline

7-isopropylbenzo[f]isoquinoline

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; tricyclohexylphosphine In 1,4-dioxane at 130℃; for 18h; Schlenk technique; Sealed tube; Inert atmosphere;86%
4-((2-methyl-6-(trifluoromethyl)pyrimidin-4-yl)oxy)aniline

4-((2-methyl-6-(trifluoromethyl)pyrimidin-4-yl)oxy)aniline

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-chloro-N-(4-((2-methyl-6-(trifluoromethyl)pyrimidin-4yl)oxy)phenyl)nicotinamide

4-chloro-N-(4-((2-methyl-6-(trifluoromethyl)pyrimidin-4yl)oxy)phenyl)nicotinamide

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;85.2%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

methyl 4-chloronicotinate
63592-85-8

methyl 4-chloronicotinate

Conditions
ConditionsYield
85%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

phenylacetonitrile
140-29-4

phenylacetonitrile

4-[α-cyano(phenyl)methyl]nicotinic acid
1345044-42-9

4-[α-cyano(phenyl)methyl]nicotinic acid

Conditions
ConditionsYield
Stage #1: 4-chloronicotinic acid; phenylacetonitrile With potassium tert-butylate In 1-methyl-pyrrolidin-2-one at 110℃; for 0.0666667h; Sealed vessel; Microwave irradiation; Inert atmosphere;
Stage #2: With hydrogenchloride In water at 0℃; pH=3;
85%
With potassium tert-butylate In 1-methyl-pyrrolidin-2-one at 130℃; for 0.5h;
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

phenylboronic acid
98-80-6

phenylboronic acid

4-phenyl-3-pyridinecarboxylic acid
103863-14-5

4-phenyl-3-pyridinecarboxylic acid

Conditions
ConditionsYield
With sodium carbonate In ethanol; water at 70℃; for 8h; Catalytic behavior; Suzuki-Miyaura Coupling;85%
With palladium diacetate; potassium carbonate; triphenylphosphine In 1,4-dioxane; water Reflux; Inert atmosphere;
4-(2-AMINOETHYL)MORPHOLINE
2038-03-1

4-(2-AMINOETHYL)MORPHOLINE

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-chloro-N-(2-morpholinoethyl)nicotinamide
1221489-82-2

4-chloro-N-(2-morpholinoethyl)nicotinamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane Reflux;84%
4-(3-Aminopropyl)morpholine
123-00-2

4-(3-Aminopropyl)morpholine

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-chloro-N-(3-morpholinopropyl)nicotinamide
1202770-39-5

4-chloro-N-(3-morpholinopropyl)nicotinamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane Reflux;84%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

methylamine
74-89-5

methylamine

4-(methylamino)nicotinic acid
1075-09-8

4-(methylamino)nicotinic acid

Conditions
ConditionsYield
In water at 165℃; for 4h; Microwave irradiation; Biotage Initiator;83%
In 1,4-dioxane; water at 100℃; for 0.833333h; Microwave irradiation;74%
In 1,4-dioxane; water at 100℃; for 0.833333h; Microwave irradiation;74%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

p-Chlorothiophenol
106-54-7

p-Chlorothiophenol

4-(4-chlorophenylthio)nicotinic acid
32896-67-6

4-(4-chlorophenylthio)nicotinic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 140 - 145℃; for 4.5h;81%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-hydroxynicotinic acid
609-70-1

4-hydroxynicotinic acid

Conditions
ConditionsYield
With water Heating;80%
With water80%
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

4-hydrazino-nicotinic acid
3323-91-9

4-hydrazino-nicotinic acid

Conditions
ConditionsYield
Stage #1: 4-chloronicotinic acid With hydrazine hydrate at 100℃; for 4h;
Stage #2: With hydrogenchloride In water pH=5;
78%
With hydrazine hydrate at 100℃; for 4h;
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

1,4-dihydro-4-oxopyridine-3-carboxylic acid
72676-96-1

1,4-dihydro-4-oxopyridine-3-carboxylic acid

Conditions
ConditionsYield
With water for 2h; Reflux;75%
With water for 2h; Reflux;
4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

carbostyril 124
19840-99-4

carbostyril 124

4-((4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)amino)nicotinic acid

4-((4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)amino)nicotinic acid

Conditions
ConditionsYield
With tin; copper; potassium carbonate Reflux;73%
morpholine
110-91-8

morpholine

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

potassium 4-morpholinonicotinate

potassium 4-morpholinonicotinate

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 120℃; for 12h;71%
With potassium carbonate In dimethyl sulfoxide at 120℃; for 12h;71%
2-isopropyliodobenzene
19099-54-8

2-isopropyliodobenzene

4-chloronicotinic acid
10177-29-4

4-chloronicotinic acid

diphenyl acetylene
501-65-5

diphenyl acetylene

7-isopropyl-5,6-diphenylbenzo[f]isoquinoline

7-isopropyl-5,6-diphenylbenzo[f]isoquinoline

Conditions
ConditionsYield
With norborn-2-ene; palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide at 130℃; for 20h; Schlenk technique; Inert atmosphere; Sealed tube; regioselective reaction;69%

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