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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (R)-Lactate supplier in China

Cas:10326-41-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

EAST CHEMSOURCES LIMITED

D(-)-lactic acid CAS RN: 10326-41-7 Molecular formula: C3H6O3 Molecular weight: 90.08 Structural formula: Properties: Colorless to yellow

D(-)-lactic acid

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (R)-lactic acid

Cas:10326-41-7

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Food Grade (R)-Lactate HACCP Manufacturer

Cas:10326-41-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

(R)-Lactate

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

D-(-)-Lactic acid

Cas:10326-41-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Leader Biochemical Group

Overview of Our Factories Our Factories production lines Our Factories R&D ability Our Factories warehouse Our Factorie

China Biggest Factory & Manufacturer supply D(-)-lactic acid

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $30.0 / 35.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

(R)-Lactate

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM - (R)-Lactate

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 10326-41-7 with competitive price

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

D-(?)-Lactic acidCAS10326-41-7

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $20.0 / 28.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Chemical Name: D-lactic acid CAS No.: 10326-41-7 Molecular Fomula:C3H6O3 Chemical Structure: Molecular weight: 90.08 Appearance: Colorless or micro - yellow clarifying viscous liquid Assay:100.0-102.0% Appearance:Clear colorless to yello

D(-)-lactic acid

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White powder Storage:Room temperature Package:25kg/drum Application:Pharmaceutical intermediates Transportation:Express/Sea/Air Port:Any port in china

High Quality D-Lactic Acid (R)-Lactate

Cas:10326-41-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Propanoic acid,2-hydroxy-, (2R)- 10326-41-7

Cas:10326-41-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Chiral drug, (R)-Lactate CAS:10326-41-7

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $30.0 / 36.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

(R)-Lactate CAS:10326-41-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate

(R)-Lactate CAS:10326-41-7

Cas:10326-41-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Propanoic acid,2-hydroxy-, (2R)-

Cas:10326-41-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Propanoic acid,2-hydroxy-, (2R)-

Cas:10326-41-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

(R)-Lactate

Cas:10326-41-7

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

D(-)-lactic acid

Cas:10326-41-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(R)-Lactate

Cas:10326-41-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(R)-Lactate

Cas:10326-41-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality D(-)-lactic acid

Cas:10326-41-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(R)-Lactate

Cas:10326-41-7

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

D-Lactic Acid

Cas:10326-41-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

C3H6O3 (R)-Lactate 10326-41-7

Cas:10326-41-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & CommercialHisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, special chemicals and OLED

(R)-Lactate

Cas:10326-41-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

D(-)-lactic acid

Cas:10326-41-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(R)-2-Hydroxypropanoic acid

Cas:10326-41-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

Enke (R)-Lactate

Cas:10326-41-7

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Lab/Research institutions

inquiry

Synthetic route

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With phosphonic Acid; lactate dehydrogenase V152R mutant; phosphorous dehydrogenase I151R mutant; NAD In aq. buffer at 30℃; for 12h; pH=7.5; Reagent/catalyst; Time; Enzymatic reaction;100%
With phosphate buffer; ADH (EC 1.1.1.2); MV2+; nicotinamide adenine dinucleotide phosphate In water; tert-butyl alcohol for 30h; electrolysis' other reaction system;8.3E-6 mol
With Leuconostoc lactis ketoacid reductase; NADH In aq. phosphate buffer at 35℃; for 10h; pH=7; Enzymatic reaction; enantioselective reaction;65.2 %Chromat.
(2R)-propane-1,2-diol
4254-14-2

(2R)-propane-1,2-diol

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
Stage #1: (2R)-propane-1,2-diol With Rh(OTf)(trop2NH)(PPh3); water; cyclohexanone; sodium hydroxide at 20℃; for 5h; Inert atmosphere;
Stage #2: With hydrogenchloride In water Inert atmosphere; chemoselective reaction;
91%
1-dodecyl L-lactate
232944-80-8

1-dodecyl L-lactate

A

D-Lactic acid
10326-41-7

D-Lactic acid

B

1-dodecyl alcohol
112-53-8

1-dodecyl alcohol

Conditions
ConditionsYield
With 2C33H37N*H2O7S2; water at 80℃; for 4h;A 80%
B 87%
methyl lactate
547-64-8

methyl lactate

A

D-Lactic acid
10326-41-7

D-Lactic acid

B

(S)-Methyl lactate
27871-49-4

(S)-Methyl lactate

Conditions
ConditionsYield
With Dactylosporangium aurantiacum esterase WDEst9 In aq. buffer at 30℃; for 3h; pH=8.5; Catalytic behavior; Concentration; pH-value; Reagent/catalyst; Solvent; Temperature; Time; Green chemistry; Enzymatic reaction; enantioselective reaction;A n/a
B 86.7%
D-Alanine
338-69-2

D-Alanine

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite82%
With trifluoroacetic acid; sodium nitrite In water at 20℃; for 6h;62%
With sulfuric acid; sodium nitrite In water at 0℃; for 2h;
Isobutyl (R)-lactate
61597-96-4

Isobutyl (R)-lactate

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 0 - 20℃; for 48h; Inert atmosphere;77%
D-Alanine
338-69-2

D-Alanine

A

D-Lactic acid
10326-41-7

D-Lactic acid

B

D-lactide
4511-42-6

D-lactide

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 0 - 20℃; stereoselective reaction;A 58%
B < 3 %Spectr.
propylene glycol
57-55-6

propylene glycol

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With phosphate buffer; Gluconobacter oxydans DSM 2003 cells at 28℃; for 20h; pH=6.0;48%
ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

A

L-Lactic acid
79-33-4

L-Lactic acid

B

D-Lactic acid
10326-41-7

D-Lactic acid

C

(R)-Ethyl lactate
7699-00-5

(R)-Ethyl lactate

Conditions
ConditionsYield
With ammonium hydroxide at 30℃; pH=6.9;A n/a
B n/a
C 34.5%
citric acid
77-92-9

citric acid

A

Oxalacetic acid
328-42-7

Oxalacetic acid

B

L-Lactic acid
79-33-4

L-Lactic acid

C

D-Lactic acid
10326-41-7

D-Lactic acid

D

3-hydroxy-2-butanon
513-86-0, 52217-02-4

3-hydroxy-2-butanon

E

acetic acid
64-19-7

acetic acid

F

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

Conditions
ConditionsYield
With Leuconostoc mesenteroides at 30℃; for 1h; potassium phosphate buffer, pH 5.0; other conditions also investigated; several substrates investigated;A 0.66%
B 0.06%
C 1.77%
D 6.86%
E 15.5%
F 0.05%
citric acid
77-92-9

citric acid

A

Oxalacetic acid
328-42-7

Oxalacetic acid

B

L-Lactic acid
79-33-4

L-Lactic acid

C

D-Lactic acid
10326-41-7

D-Lactic acid

D

acetic acid
64-19-7

acetic acid

E

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

F

dimethylglyoxal
431-03-8

dimethylglyoxal

Conditions
ConditionsYield
With Leuconostoc mesenteroides at 30℃; for 1h; potassium phosphate buffer, pH 5.0; other conditions also investigated; several substrates investigated;A 0.66%
B 0.06%
C 1.77%
D 15.5%
E 0.05%
F 1.72%
LACTIC ACID
849585-22-4

LACTIC ACID

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
mit Hilfe von Chinin;
mit Hilfe von Morphin;
With MORPHIN
mit Hilfe von Strychnin;
D-Fructose
57-48-7

D-Fructose

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
bei der Vergaerung durch Bacterium coli communis (zu mehr als 75prozent aus l-Milchsaeure besteht);
bei der Vergaerung durch Lactobacillus Leichmanni;
pyruvic acid menthyl ester
53651-68-6

pyruvic acid menthyl ester

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With aluminium amalgam und Verseifung der Produkte mit alkoholischem Kaliumhydroxyd;
(R)-2-chloropropionic acid
7474-05-7

(R)-2-chloropropionic acid

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With water; silver(l) oxide
(S)-2-bromopropanoic acid
32644-15-8

(S)-2-bromopropanoic acid

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With potassium hydroxide
R-(+)-2-bromopropionic acid
10009-70-8

R-(+)-2-bromopropionic acid

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With water; silver carbonate
(S)-2-iodo-propionic acid
18791-44-1

(S)-2-iodo-propionic acid

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
Hydrolysis;
(S)-2-iodo-propionic acid
18791-44-1

(S)-2-iodo-propionic acid

A

LACTIC ACID
849585-22-4

LACTIC ACID

B

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With sodium hydroxide Hydrolysis;
mannitol
69-65-8

mannitol

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
bei der Vergaerung durch eine auf Birnen gefundene Mikrobe;
bei der Vergaerung durch Bacterium formicicum;
durch Vergaerung mit Pneumokokkus(Friedlaender);
mannitol
69-65-8

mannitol

A

ethanol
64-17-5

ethanol

B

D-Lactic acid
10326-41-7

D-Lactic acid

C

acetic acid
64-19-7

acetic acid

D

butan-1-ol
71-36-3

butan-1-ol

Conditions
ConditionsYield
bei der Vergaerung durch Clostridium thermocellum;Produkt 5:Buttersaeure;
D-sorbitol
50-70-4

D-sorbitol

A

D-Fructose
57-48-7

D-Fructose

B

D-Lactic acid
10326-41-7

D-Lactic acid

C

D-glucose
50-99-7

D-glucose

Conditions
ConditionsYield
beim Durchleiten von sorbithaltigem Rinderblut durch isolierte Hundeleber;
L-arabinose
5328-37-0

L-arabinose

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
durch Vergaerung mit Pneumokokkus(Friedlaender);
2-amino-2-deoxyglucose
3416-24-8

2-amino-2-deoxyglucose

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
bei der Einw. von Bac. subtilis und Bac. prodigiosus;
D-glucose
50-99-7

D-glucose

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
bei der Gaerung der alkalischen Loesungen durch den Bacillus acidi laevolactici;
at 36℃; bei der Gaerung der alkalischen Loesungen durch den Bacillus acidi laevolactici;
bei der Vergaerung durch eine auf Birnen gefundene Mikrobe;
D-Galactose
59-23-4

D-Galactose

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
durch Vergaerung mit Pneumokokkus(Friedlaender);
bei der Vergaerung durch Lactobacillus Leichmanni;
Conditions
ConditionsYield
bei der Gaerung der alkalischen Loesungen durch den Typhusbazillus;
durch Vergaerung mit Pneumokokkus(Friedlaender);
durch den Pilz Rhizopus chinensis;
beim Vergaeren durch Betacoccus arabinosaceus;
Vergaerung durch Lactobacillus leichmannii sowie Reinigung ueber das Zinksalz und durch folgende Einw. eines Ionenaustausch-Harzes;
D-glucosaminic acid
3646-68-2

D-glucosaminic acid

A

D-Lactic acid
10326-41-7

D-Lactic acid

B

succinic acid
110-15-6

succinic acid

Conditions
ConditionsYield
durch Escherishia Coli;
D-glucosaminic acid
3646-68-2

D-glucosaminic acid

A

D-Lactic acid
10326-41-7

D-Lactic acid

B

oxalic acid
144-62-7

oxalic acid

C

acetic acid
64-19-7

acetic acid

Conditions
ConditionsYield
nach Verabreichung an Hunde und Kaninchen im Harn ausscheiden;
fructose-1,6-bisphosphate
488-69-7

fructose-1,6-bisphosphate

D-Lactic acid
10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With GLUTATHIONE; toluene bei der Vergaerung durch Hefe;
With GLUTATHIONE; toluene bei der Vergaerung durch Hefe; in diesen Gaerensaetzen entsteht vielleicht intermediaer Methylglyoxal durch einen nichtfermentativen Prozess;
D-Lactic acid
10326-41-7

D-Lactic acid

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

Conditions
ConditionsYield
With oxygen at 100℃; under 75.0075 Torr; for 8h; Temperature; Pressure; Autoclave;94.3%
With mutant 3-isopropylmalate dehydrogenase(Gly89-Gly-Leu90); nicotinamide adenine dinucleotide In water at 60℃; for 2h; pH=7.8; Enzyme kinetics;
With nicotinamide flucytosine dinucleotide at 25℃; pH=7.5; aq. buffer; Enzymatic reaction;
With D-lactate dehydrogenase of Planctomyces brasiliensis at 25℃; for 1h; pH=7; Concentration; pH-value; Reagent/catalyst; Temperature; Enzymatic reaction;
With D-lactate oxidase from Saccharomyces cerevisiae; oxygen; catalase In aq. buffer at 30℃; pH=7.4; Reagent/catalyst; Enzymatic reaction;
D-Lactic acid
10326-41-7

D-Lactic acid

didecyldimethylammonium chloride
7173-51-5

didecyldimethylammonium chloride

didecyldimethylammonium L-lactate
1308889-80-6

didecyldimethylammonium L-lactate

Conditions
ConditionsYield
Stage #1: D-Lactic acid With potassium hydroxide In water Reflux;
Stage #2: didecyldimethylammonium chloride In water at 20℃; for 5h;
94%
D-Lactic acid
10326-41-7

D-Lactic acid

((S)-1-Phenyl-ethyl)-{4-[6-piperidin-4-yl-3-(3-trifluoromethyl-phenyl)-pyridazin-4-yl]-pyrimidin-2-yl}-amine
271247-18-8

((S)-1-Phenyl-ethyl)-{4-[6-piperidin-4-yl-3-(3-trifluoromethyl-phenyl)-pyridazin-4-yl]-pyrimidin-2-yl}-amine

(R)-2-Hydroxy-1-{4-[5-[2-((S)-1-phenyl-ethylamino)-pyrimidin-4-yl]-6-(3-trifluoromethyl-phenyl)-pyridazin-3-yl]-piperidin-1-yl}-propan-1-one

(R)-2-Hydroxy-1-{4-[5-[2-((S)-1-phenyl-ethylamino)-pyrimidin-4-yl]-6-(3-trifluoromethyl-phenyl)-pyridazin-3-yl]-piperidin-1-yl}-propan-1-one

Conditions
ConditionsYield
With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide93%
D-Lactic acid
10326-41-7

D-Lactic acid

9-anthryldiazomethane
10401-59-9

9-anthryldiazomethane

(R)-2-Hydroxy-propionic acid anthracen-9-ylmethyl ester

(R)-2-Hydroxy-propionic acid anthracen-9-ylmethyl ester

Conditions
ConditionsYield
In diethyl ether for 0.5h; Ambient temperature;90%
In diethyl ether for 0.5h; Ambient temperature;
In methanol at 20℃; for 0.5h;
D-Lactic acid
10326-41-7

D-Lactic acid

benzyl alcohol
100-51-6

benzyl alcohol

Conditions
ConditionsYield
Stage #1: benzyl alcohol With toluene-4-sulfonic acid In benzene for 0.5h; Reflux;
Stage #2: D-Lactic acid In benzene Reflux;
88%
With salicylaldehyde In toluene at 100℃; for 18h; Inert atmosphere; chemoselective reaction;85%
With hydrogenchloride for 18h;51.3%
D-Lactic acid
10326-41-7

D-Lactic acid

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(2S)-2-<(tert-Butyldimethylsilyl)oxy>lactic acid
129919-88-6

(2S)-2-<(tert-Butyldimethylsilyl)oxy>lactic acid

Conditions
ConditionsYield
With dmap; triethylamine87%
ethanol
64-17-5

ethanol

D-Lactic acid
10326-41-7

D-Lactic acid

(R)-Ethyl lactate
7699-00-5

(R)-Ethyl lactate

Conditions
ConditionsYield
With salicylaldehyde at 80℃; for 28h; Inert atmosphere; chemoselective reaction;85%
With sulfuric acid at 120℃; for 8h; Molecular sieve;25%
With hydrogenchloride
With sulfuric acid; benzene durch azeotrope Destillation;
D-Lactic acid
10326-41-7

D-Lactic acid

9-(6-methoxypyridin-3-yl)-3-methyl-1-(piperidin-4-yl)-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one hydrochloride salt

9-(6-methoxypyridin-3-yl)-3-methyl-1-(piperidin-4-yl)-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one hydrochloride salt

(R)-1-[1-(2-hydroxypropionyl)piperidine-4-yl]-9-(6-methoxypyridin-3-yl)-3-methyl-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one

(R)-1-[1-(2-hydroxypropionyl)piperidine-4-yl]-9-(6-methoxypyridin-3-yl)-3-methyl-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 9-(6-methoxypyridin-3-yl)-3-methyl-1-(piperidin-4-yl)-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one hydrochloride salt With triethylamine In dichloromethane at 20℃; for 0.5h;
Stage #2: D-Lactic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h;
81.4%
Stage #1: 9-(6-methoxypyridin-3-yl)-3-methyl-1-(piperidin-4-yl)-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one hydrochloride salt With triethylamine In dichloromethane at 20℃; for 0.5h;
Stage #2: D-Lactic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h;
88mg
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane; water at 20℃; for 2h;88 mg
D-Lactic acid
10326-41-7

D-Lactic acid

methyl 4-({4-[3-cyano-4-(piperidin-4-yloxy)phenyl]pyrimidin-2-yl}amino)benzoate
1292317-84-0

methyl 4-({4-[3-cyano-4-(piperidin-4-yloxy)phenyl]pyrimidin-2-yl}amino)benzoate

trifluoroacetic acid
76-05-1

trifluoroacetic acid

methyl 4-({4-[3-cyano-4-({1-[(2R)-2-hydroxypropanoyl]piperidin-4-yl}oxy)phenyl]pyrimidin-2-yl}amino)benzoate trifluoroacetate

methyl 4-({4-[3-cyano-4-({1-[(2R)-2-hydroxypropanoyl]piperidin-4-yl}oxy)phenyl]pyrimidin-2-yl}amino)benzoate trifluoroacetate

Conditions
ConditionsYield
Stage #1: D-Lactic acid; methyl 4-({4-[3-cyano-4-(piperidin-4-yloxy)phenyl]pyrimidin-2-yl}amino)benzoate With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide for 16h;
Stage #2: trifluoroacetic acid In water; acetonitrile
81%
1,10-Phenanthroline
66-71-7

1,10-Phenanthroline

malachite

malachite

D-Lactic acid
10326-41-7

D-Lactic acid

[copper(II)-di(lactato)-(1,10-phenanthroline)]*4H2O

[copper(II)-di(lactato)-(1,10-phenanthroline)]*4H2O

Conditions
ConditionsYield
In ethanol suspn. of Cu compd. and lactic acid in EtOH refluxed for 4 h at 75°C, 1,10-phenanthroline added, refluxed for 2 h, then stirred for several d; filtered, washed with EtOH, dried over CaCl2; elem. anal.;80%
D-Lactic acid
10326-41-7

D-Lactic acid

vanadia

vanadia

bis(triphenylphosphine)iminium chloride
21050-13-5

bis(triphenylphosphine)iminium chloride

[VO2(lac)]2(Ph3P=NPPh3)2

[VO2(lac)]2(Ph3P=NPPh3)2

Conditions
ConditionsYield
With tetraethylammonium hydroxide In water; acetonitrile V2O5 was added to aq. soln. Et4NOH and warmed to 60°C, soln. was filtered, lactic acid was added with stirring, pH was raised from 3.0 to6.3 by Et4NOH, soln. was concd. in air stream, soln. PPNCl in MeCN was added and left overnight; product was filtered, washed with MeCN, and dried in vacuo; elem. anal.;78%
D-Lactic acid
10326-41-7

D-Lactic acid

(rac)-4-bromo-5,6,7,8-tetrahydroisoquinolin-8-amine
1428651-87-9

(rac)-4-bromo-5,6,7,8-tetrahydroisoquinolin-8-amine

(R)-N-((R,S)-4-bromo-5,6,7,8-tetrahydro-isoquinolin-8-yl)-2-hydroxy-propionamide
1469979-88-1

(R)-N-((R,S)-4-bromo-5,6,7,8-tetrahydro-isoquinolin-8-yl)-2-hydroxy-propionamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; Inert atmosphere;77%
D-Lactic acid
10326-41-7

D-Lactic acid

5-{9-(cyclopropylmethyl)-8-[(3R)-3-methylpiperazin-1-yl]-6-morpholin-4-yl-9H-purin-2-yl}pyrimidin-2-amine
1222104-79-1

5-{9-(cyclopropylmethyl)-8-[(3R)-3-methylpiperazin-1-yl]-6-morpholin-4-yl-9H-purin-2-yl}pyrimidin-2-amine

(2R)-1-{(2R)-4-[2-(2-Aminopyrimidin-5-yl)-9-(cyclopropylmethyl)-6-morpholin-4-yl-9H-purin-8-yl]-2-methylpiperazin-1-yl}-1-oxopropan-2-ol
1222104-99-5

(2R)-1-{(2R)-4-[2-(2-Aminopyrimidin-5-yl)-9-(cyclopropylmethyl)-6-morpholin-4-yl-9H-purin-8-yl]-2-methylpiperazin-1-yl}-1-oxopropan-2-ol

Conditions
ConditionsYield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide In dichloromethane; N,N-dimethyl-formamide at 20 - 40℃; for 40.5h;76%
D-Lactic acid
10326-41-7

D-Lactic acid

benzyl bromide
100-39-0

benzyl bromide

Conditions
ConditionsYield
Stage #1: D-Lactic acid With caesium carbonate In methanol; water pH=7;
Stage #2: benzyl bromide In methanol; water; N,N-dimethyl-formamide at 20℃; for 6h;
75%
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 80 - 100℃; for 1h;68%
With potassium carbonate In N,N-dimethyl-formamide for 14h; Ambient temperature;
In N,N-dimethyl-formamide at 50℃; for 6h; Inert atmosphere; Glovebox; Sealed tube;
D-Lactic acid
10326-41-7

D-Lactic acid

(rac)-6-(8-amino-5,6,7,8-tetrahydroisoquinolin-4-yl)-1-methyl-3,4-dihydroquinolin-2(1H)-one
1428651-83-5

(rac)-6-(8-amino-5,6,7,8-tetrahydroisoquinolin-4-yl)-1-methyl-3,4-dihydroquinolin-2(1H)-one

(2R)-2-hydroxy-N-[(4R,S)-4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide
1428652-31-6

(2R)-2-hydroxy-N-[(4R,S)-4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; diisopropylamine In dichloromethane at 0 - 20℃; Inert atmosphere;75%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; Inert atmosphere;75%
D-Lactic acid
10326-41-7

D-Lactic acid

3-(((1R,2R)-2-((4-(6-fluorobenzo[d]isoxazole-3-yl)piperidin-1-yl)methyl)cyclohexyl)methyl)oxazolidine-2-one

3-(((1R,2R)-2-((4-(6-fluorobenzo[d]isoxazole-3-yl)piperidin-1-yl)methyl)cyclohexyl)methyl)oxazolidine-2-one

3-(((1R,2R)-2-((4-(6-fluorobenzo[d]isoxazole-3-yl)piperidin-1-yl)methyl)cyclohexyl)methyl)oxazolidine-2-one lactic acid salt

3-(((1R,2R)-2-((4-(6-fluorobenzo[d]isoxazole-3-yl)piperidin-1-yl)methyl)cyclohexyl)methyl)oxazolidine-2-one lactic acid salt

Conditions
ConditionsYield
In ethanol Reflux;74.1%
D-Lactic acid
10326-41-7

D-Lactic acid

(R)-3-iodo-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

(R)-3-iodo-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

(R)-1-((R)-3-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-hydroxypropan-1-one

(R)-1-((R)-3-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-hydroxypropan-1-one

Conditions
ConditionsYield
Stage #1: D-Lactic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: (R)-3-iodo-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine In N,N-dimethyl-formamide at 20℃; for 5h;
73.3%
D-Lactic acid
10326-41-7

D-Lactic acid

5-(9-isobutyl-6-morpholin-4-yl-8-piperazin-1-yl-9H-purin-2-yl)pyrimidin-2-amine
1222105-31-8

5-(9-isobutyl-6-morpholin-4-yl-8-piperazin-1-yl-9H-purin-2-yl)pyrimidin-2-amine

(2R)-1-{4-[2-(2-Aminopyrimidin-5-yl)-9-isobutyl-6-morpholin-4-yl-9H-purin-8-yl]piperazin-1-yl}-1-oxopropan-2-ol
1222104-78-0

(2R)-1-{4-[2-(2-Aminopyrimidin-5-yl)-9-isobutyl-6-morpholin-4-yl-9H-purin-8-yl]piperazin-1-yl}-1-oxopropan-2-ol

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃; for 96h;73%
D-Lactic acid
10326-41-7

D-Lactic acid

5-bromo-3-fluoro-N1-(propan-2-yl)benzene-1,2-diamine

5-bromo-3-fluoro-N1-(propan-2-yl)benzene-1,2-diamine

(1R)-1-[6-bromo-4-fluoro-1-(propan-2-yl)-1H-benzimidazol-2-yl]ethan-1-ol

(1R)-1-[6-bromo-4-fluoro-1-(propan-2-yl)-1H-benzimidazol-2-yl]ethan-1-ol

Conditions
ConditionsYield
for 44h; Time; Heating;71%
D-Lactic acid
10326-41-7

D-Lactic acid

5-amino-N-(4-(azepan-4-yloxy)pyrimidin-5-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide
1422470-13-0

5-amino-N-(4-(azepan-4-yloxy)pyrimidin-5-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide

C20H20F2N6O2S*C3H6O3

C20H20F2N6O2S*C3H6O3

Conditions
ConditionsYield
In methanol; dichloromethane at 20 - 30℃; for 0.5h;67.8%
D-Lactic acid
10326-41-7

D-Lactic acid

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

L-lactic acid O-carboxyanhydride
91049-50-2

L-lactic acid O-carboxyanhydride

Conditions
ConditionsYield
With pyrographite In tetrahydrofuran at 0 - 20℃; for 8h;65%
D-Lactic acid
10326-41-7

D-Lactic acid

5-chloro-N-[3,5-dimethyl-1-(4-piperidinyl)-1H-pyrazol-4-yl]-4-(pyrazolo[1,5-a]pyridin-3-yl)-2-pyrimidinamine

5-chloro-N-[3,5-dimethyl-1-(4-piperidinyl)-1H-pyrazol-4-yl]-4-(pyrazolo[1,5-a]pyridin-3-yl)-2-pyrimidinamine

(2R)-1-[4-(4-{[5-chloro-4-(pyrazolo[1,5-a]pyridin-3-yl)-2-pyrimidinyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)-1-piperidinyl]-2-hydroxy-1-propanone

(2R)-1-[4-(4-{[5-chloro-4-(pyrazolo[1,5-a]pyridin-3-yl)-2-pyrimidinyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)-1-piperidinyl]-2-hydroxy-1-propanone

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;64%
D-Lactic acid
10326-41-7

D-Lactic acid

3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-(4-piperidin-3-yl)phenyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one hydrochloride

3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-(4-piperidin-3-yl)phenyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one hydrochloride

1-(4-(1-((R)-2-hydroxypropionyl)piperidin-3-yl)phenyl)3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-2-(3H)-one

1-(4-(1-((R)-2-hydroxypropionyl)piperidin-3-yl)phenyl)3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-2-(3H)-one

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃;63.4%
D-Lactic acid
10326-41-7

D-Lactic acid

tert-butyl 4-[(6-aminothieno[3,2-b]pyridin-7-yl)amino]-3-fluoropiperidine-1-carboxylate
1607590-13-5

tert-butyl 4-[(6-aminothieno[3,2-b]pyridin-7-yl)amino]-3-fluoropiperidine-1-carboxylate

tert-butyl 3-fluoro-4-[(6-{[(2R)-2-hydroxypropanoyl]amino}thieno[3,2-b]pyridin-7-yl)amino]piperidine-1-carboxylate
1607590-14-6

tert-butyl 3-fluoro-4-[(6-{[(2R)-2-hydroxypropanoyl]amino}thieno[3,2-b]pyridin-7-yl)amino]piperidine-1-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃;62%

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