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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (S)-Tert-Leucinol supplier in China

Cas:112245-13-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product specifica

(S)-tert-Leucinol

Cas:112245-13-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

L-tert-Leucinol

Cas:112245-13-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

(S)-TERT-LEUCINOL Basic information Product Name: (S)-TERT-LEUCINOL Synonyms: 2-AMINO-3,3-DIMETHYL-1-BUTANOL;H-TLE-OL;H-(TBU)GLY-OL;L-T-LEUCINOL;L-(+)-TERT-LEUCINOL

(S)-TERT-LEUCINOL

Cas:112245-13-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product Name: L-Tert-Leucinol Cas:112245-13-3 MF:C6H15NO MW:117.189 Appearance:White Crystalline Powder Storage:Store in cool and dry place, away from sun light. Package:25kg Application:APIs Transportation:By sea or by air Port:Qingdao Port

L-Tert-Leucinol

Cas:112245-13-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 112245-13-3 with best quality

Cas:112245-13-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality L-Tert-Leucinol CAS 112245-13-3

Cas:112245-13-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

(S)-TERT-LEUCINOL

Cas:112245-13-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

(S)-TERT-LEUCINOL CAS: 112245-13-3

Cas:112245-13-3

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Butanol,2-amino-3,3-dimethyl-, (2S)- 112245-13-3

Cas:112245-13-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

L-tert-Leucinol 99%

Cas:112245-13-3

Min.Order:1 Gram

FOB Price: $76.0 / 99.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

(S)-TERT-LEUCINOL CAS:112245-13-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

(S)-TERT-LEUCINOL CAS:112245-13-3

Cas:112245-13-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Butanol,2-amino-3,3-dimethyl-, (2S)-

Cas:112245-13-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Butanol,2-amino-3,3-dimethyl-, (2S)-

Cas:112245-13-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

(S)-Tert-Leucinol

Cas:112245-13-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:white powder/crystal Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/A

(S)-tert-Leucinol

Cas:112245-13-3

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(S)-TERT-LEUCINOL

Cas:112245-13-3

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

Lower Price (S)-tert-Leucinol

Cas:112245-13-3

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-benzylpyrrolidin-3-amine

Cas:112245-13-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(S)-TERT-LEUCINOL

Cas:112245-13-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality (S)-Tert-Leucinol

Cas:112245-13-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

L-tert-Leucinol

Cas:112245-13-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: (S)-TERT-LEUCINOL CAS: 112245-13-3 MF: C6H15NO MW: 117.19 EINECS: Mol File: 112245-13-3.mol (S)-TERT-LEUCINOL Structure (S)-TERT-LEUCINOL Chemical Properties Melting point 30-34 °C(lit.) Boiling point 11

(S)-TERT-LEUCINOL

Cas:112245-13-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

(S)-TERT-LEUCINOL

Cas:112245-13-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(S)-TERT-LEUCINOL

Cas:112245-13-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(L)-tert-Leucinol

Cas:112245-13-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

(s)-tert-leucinol

Cas:112245-13-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

L-tert-Leucinol

Cas:112245-13-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD. founded in 1984, engages in pharmaceutical research, development, production, process design and technical consultation of synthetic and fermentation pharmaceutical products. The organizational s

(S)-tert-Leucinol 112245-13-3 manufacturer/high quality/in stock

Cas:112245-13-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Research Peptide Biotechnology Co., Ltd.

High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research

1-Butanol,2-amino-3,3-dimethyl-, (2S)-

Cas:112245-13-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

L-tert-Leucine
20859-02-3

L-tert-Leucine

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
With sodium tetrahydroborate; iodine In tetrahydrofuran for 24h; Heating;100%
Stage #1: L-tert-Leucine With iodine In tetrahydrofuran for 24h; Reflux;
Stage #2: With methanol
Stage #3: With potassium hydroxide In water
100%
With sodium tetrahydroborate; iodine In tetrahydrofuran at 0 - 80℃; for 22h; Inert atmosphere;100%
[2-[(4S)-4-(tert-butyl-1,3-oxazolin-2-yl)]phenyl]diphenylphosphino-1-one
297746-06-6

[2-[(4S)-4-(tert-butyl-1,3-oxazolin-2-yl)]phenyl]diphenylphosphino-1-one

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
With hydrogenchloride for 6h; Hydrolysis; Heating;85%
(-)-(3R,5S)-5-(1,1-dimethylethyl)-3-phenylmorpholin-2-one
157985-17-6

(-)-(3R,5S)-5-(1,1-dimethylethyl)-3-phenylmorpholin-2-one

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol under 112509 Torr; for 72h;82%
With hydrogen; palladium on activated charcoal In methanol under 114000 Torr; for 72h; Hydrogenolysis; ring cleavage; methanolysis;82%
L-tert-leucine methyl ester hydrochloride
63038-27-7

L-tert-leucine methyl ester hydrochloride

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol; water for 5.5h; Heating;
sodium 3,3-dimethyl-2-oxobutyrate
43165-46-4

sodium 3,3-dimethyl-2-oxobutyrate

A

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

B

(2R)-2-amino-3,3-dimethylbutan-1-ol
3907-02-6, 93684-72-1, 112245-13-3, 112245-09-7

(2R)-2-amino-3,3-dimethylbutan-1-ol

Conditions
ConditionsYield
With sodium tetrahydroborate; sulfuric acid In 1,2-dimethoxyethane for 48h; Ambient temperature; resolution with (S)-mandelic acid; Yield given. Yields of byproduct given;
With sodium tetrahydroborate; sulfuric acid In 1,2-dimethoxyethane for 48h; Ambient temperature; resolution with N-(2-naphthoyl)-(S)-tert-leucine; Yield given. Yields of byproduct given;
(S)-3,3-Dimethyl-2-((S)-1-phenyl-ethylamino)-butan-1-ol
207398-94-5

(S)-3,3-Dimethyl-2-((S)-1-phenyl-ethylamino)-butan-1-ol

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
With hydrogen S, Ram, L. D. Spicer Synth. Commun. 1987, 17, 415.;
1-Bromopinacolon
5469-26-1

1-Bromopinacolon

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 90 percent / dimethylformamide / 15 h / 20 °C
2: hydrobromic acid; acetic acid
3: potassium carbonate
4: hydrogen / platinum oxide hydrate / methanol / 20 °C / 760 Torr
5: 82 percent / hydrogen / Pd/C / methanol / 72 h / 114000 Torr
View Scheme
5-(1,1-dimethylethyl)-3R-phenyl-3,6-dihydro-[1,4]oxazin-2-one
157985-06-3

5-(1,1-dimethylethyl)-3R-phenyl-3,6-dihydro-[1,4]oxazin-2-one

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen / platinum oxide hydrate / methanol / 20 °C / 760 Torr
2: 82 percent / hydrogen / Pd/C / methanol / 72 h / 114000 Torr
View Scheme
Multi-step reaction with 2 steps
1: 89 percent / H2 / PtO2 / methanol / 5 h / 760 Torr
2: 82 percent / H2 / 10percent Pd/C / methanol / 72 h / 112509 Torr
View Scheme
(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3,3-dimethyl-2-oxo-butyl ester
261963-27-3

(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3,3-dimethyl-2-oxo-butyl ester

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrobromic acid; acetic acid
2: potassium carbonate
3: hydrogen / platinum oxide hydrate / methanol / 20 °C / 760 Torr
4: 82 percent / hydrogen / Pd/C / methanol / 72 h / 114000 Torr
View Scheme
Multi-step reaction with 3 steps
1: aq. HBr / acetic acid
2: 89 percent / H2 / PtO2 / methanol / 5 h / 760 Torr
3: 82 percent / H2 / 10percent Pd/C / methanol / 72 h / 112509 Torr
View Scheme
(R)-Amino-phenyl-acetic acid 3,3-dimethyl-2-oxo-butyl ester; hydrobromide

(R)-Amino-phenyl-acetic acid 3,3-dimethyl-2-oxo-butyl ester; hydrobromide

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate
2: hydrogen / platinum oxide hydrate / methanol / 20 °C / 760 Torr
3: 82 percent / hydrogen / Pd/C / methanol / 72 h / 114000 Torr
View Scheme
pivalaldehyde
630-19-3

pivalaldehyde

H2N-Val-Phe-PAL-TM support

H2N-Val-Phe-PAL-TM support

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 4 Angstroem mol. sieves / CH2Cl2
2: TiCl4 / 15 °C / Irradiation
3: H2 / S, Ram, L. D. Spicer Synth. Commun. 1987, 17, 415.
View Scheme
[2,2-Dimethyl-prop-(E)-ylidene]-((S)-1-phenyl-ethyl)-amine
207398-91-2

[2,2-Dimethyl-prop-(E)-ylidene]-((S)-1-phenyl-ethyl)-amine

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: TiCl4 / 15 °C / Irradiation
2: H2 / S, Ram, L. D. Spicer Synth. Commun. 1987, 17, 415.
View Scheme
1-hydroxy-3,3-dimethylbutan-2-one
38895-88-4

1-hydroxy-3,3-dimethylbutan-2-one

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
With ammonium hydroxide; formate dehydrogenase; amine dehydrogenase-M0; H3N*CH2O2*H(1+); nicotinamide adenine dinucleotide In dimethyl sulfoxide at 30℃; for 24h; pH=8.9; Reagent/catalyst; enantioselective reaction;
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-2-tert-Butyl-1-trifluoromethanesulfonyl-aziridine
200351-78-6

(S)-2-tert-Butyl-1-trifluoromethanesulfonyl-aziridine

Conditions
ConditionsYield
With triethylamine In dichloromethane at -78 - -30℃;100%
With triethylamine In dichloromethane at -78 - -50℃; for 15h;
3,5-di-tert-butyl-2-hydroxybenzaldehyde
37942-07-7

3,5-di-tert-butyl-2-hydroxybenzaldehyde

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

2,4-di-tert-butyl-6-[(E)-{[(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]imino}methyl]phenol

2,4-di-tert-butyl-6-[(E)-{[(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]imino}methyl]phenol

Conditions
ConditionsYield
In ethanol for 3h; Heating;100%
With magnesium sulfate In methanol for 16h;93%
In ethanol Heating;
3,5-diodosalicylaldehyde
2631-77-8

3,5-diodosalicylaldehyde

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S,E)-2-(((1-hydroxy-3,3-dimethylbutan-2-yl)imino)methyl)-4,6-diiodophenol

(S,E)-2-(((1-hydroxy-3,3-dimethylbutan-2-yl)imino)methyl)-4,6-diiodophenol

Conditions
ConditionsYield
With sodium sulfate In methanol for 12h; Heating;100%
In ethanol for 16h;75%
In dichloromethane at 20℃; for 16h;
2-methyl-benzyl alcohol
89-95-2

2-methyl-benzyl alcohol

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-2-(N-salicylidene)amino-3,3-dimethyl-1-butanol
946411-09-2

(S)-2-(N-salicylidene)amino-3,3-dimethyl-1-butanol

Conditions
ConditionsYield
With sodium sulfate In methanol for 12h; Heating;100%
In ethanol at 20℃;
3-tert-butyl-4-hydroxy-5-oxomethylphenyl vinyl carbonate

3-tert-butyl-4-hydroxy-5-oxomethylphenyl vinyl carbonate

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-3-tert-butyl-4-hydroxy-5-[(1-tert-butyl-2-hydroxy-ethylimino)-methyl]-phenyl vinyl carbonate

(S)-3-tert-butyl-4-hydroxy-5-[(1-tert-butyl-2-hydroxy-ethylimino)-methyl]-phenyl vinyl carbonate

Conditions
ConditionsYield
In ethanol at 20℃; for 6h;100%
3-tert-butyl-4-hydroxy-5-oxomethylphenyl methacrylate

3-tert-butyl-4-hydroxy-5-oxomethylphenyl methacrylate

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-3-tert-butyl-4-hydroxy-5-[(1-tert-butyl-2-hydroxy-ethylimino)-methyl]-phenyl methacrylate

(S)-3-tert-butyl-4-hydroxy-5-[(1-tert-butyl-2-hydroxy-ethylimino)-methyl]-phenyl methacrylate

Conditions
ConditionsYield
In ethanol at 20℃; for 6h;100%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

N1,N3-bis[(S)-1-hydroxy-3,3-dimethylbutan-2-yl]malonamide
909713-82-2

N1,N3-bis[(S)-1-hydroxy-3,3-dimethylbutan-2-yl]malonamide

Conditions
ConditionsYield
at 110℃; for 72h;100%
In toluene at 120℃;82%
at 120℃; for 72h; Schlenk technique; Inert atmosphere;
at 120℃; for 72h; Schlenk technique; Inert atmosphere;
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

benzyl chloroformate
501-53-1

benzyl chloroformate

((S)-1-Hydroxymethyl-2,2-dimethyl-propyl)-carbamic acid benzyl ester
848777-16-2

((S)-1-Hydroxymethyl-2,2-dimethyl-propyl)-carbamic acid benzyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃;100%
With sodium hydrogencarbonate In methanol; water for 16h;52%
With sodium hydrogencarbonate In water; ethyl acetate at 0℃; for 2h;
m-bromobenzoic aldehyde
3132-99-8

m-bromobenzoic aldehyde

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

C13H18BrNO

C13H18BrNO

Conditions
ConditionsYield
In methanol at 20℃; for 1h;100%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

C13H18N2O3

C13H18N2O3

Conditions
ConditionsYield
In methanol at 20℃; for 1h;100%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

C14H21NO2

C14H21NO2

Conditions
ConditionsYield
In methanol at 20℃; for 1h;100%
3-phenylpropanoic acid methyl ester
103-25-3

3-phenylpropanoic acid methyl ester

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-2-phenethyl-4-tert-butyloxazoline
475571-08-5

(S)-2-phenethyl-4-tert-butyloxazoline

Conditions
ConditionsYield
Zn4(OCOCF3)6O In chlorobenzene for 18h; Product distribution / selectivity; Heating / reflux;100%
With Zn4(OCOCF3)6O In chlorobenzene for 18h; Heating;99%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

3-Phenylpropionic acid
501-52-0

3-Phenylpropionic acid

(S)-2-phenethyl-4-tert-butyloxazoline
475571-08-5

(S)-2-phenethyl-4-tert-butyloxazoline

Conditions
ConditionsYield
Zn4(OCOCF3)6O In chlorobenzene for 12h; Product distribution / selectivity; Heating / reflux;100%
With Zn4(OCOCF3)6O In chlorobenzene for 12h; Heating;99%
dimethyl 4-chloro-2,6-pyridinedicarboxylate
5371-70-0

dimethyl 4-chloro-2,6-pyridinedicarboxylate

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

4-chloro-N,N'-bis[(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]pyridine-2,6-dicarboxamide
1009339-34-7

4-chloro-N,N'-bis[(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]pyridine-2,6-dicarboxamide

Conditions
ConditionsYield
at 120℃; for 2h; Inert atmosphere;100%
at 120℃; for 3.5h;
1,3-dihydro-1-iminoisobenzofuran hydrochloride
1195988-94-3

1,3-dihydro-1-iminoisobenzofuran hydrochloride

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-2-(2'-hydroxymethylphenyl)-4-tertbutyloxazoline
1196988-63-2

(S)-2-(2'-hydroxymethylphenyl)-4-tertbutyloxazoline

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 48h; Inert atmosphere;100%
(1aS,5aS)-2-(pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid
1268882-99-0

(1aS,5aS)-2-(pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(4aS,5aS)-N-((S)-1-hydroxy-3,3-dimethylbutan-2-yl)-1-(pyrazin-2-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxamide
1268881-17-9

(4aS,5aS)-N-((S)-1-hydroxy-3,3-dimethylbutan-2-yl)-1-(pyrazin-2-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxamide

Conditions
ConditionsYield
Stage #1: (1aS,5aS)-2-(pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid With triethylamine; HATU In N,N-dimethyl-formamide at 23℃; for 0.0833333h;
Stage #2: (S)-tert-leucinol In N,N-dimethyl-formamide at 23℃; for 0.25h;
100%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

trifluoroacetic acid
76-05-1

trifluoroacetic acid

(S)-1-hydroxy-3,3-dimethylbutan-2-aminium trifluoroacetate

(S)-1-hydroxy-3,3-dimethylbutan-2-aminium trifluoroacetate

Conditions
ConditionsYield
In dichloromethane at 0℃; for 0.0833333h; Inert atmosphere;100%
C14H19NO3
1207620-43-6

C14H19NO3

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

C18H28N2O3

C18H28N2O3

Conditions
ConditionsYield
In dichloromethane for 16h; Reflux;100%
3-tert-butyl-2-hydroxybenzaldehyde
24623-65-2

3-tert-butyl-2-hydroxybenzaldehyde

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-2-[N-(3'-tert-butylsalicylidene)amino]-3,3-dimethyl-1-butanol

(S)-2-[N-(3'-tert-butylsalicylidene)amino]-3,3-dimethyl-1-butanol

Conditions
ConditionsYield
99%
With sodium sulfate In methanol for 18h; Heating;70%
With sodium sulfate In methanol Heating;70%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

2-Fluorobenzoyl chloride
393-52-2

2-Fluorobenzoyl chloride

(+)-(S)-2-fluoro-N-(2-hydroxymethyl-2,2-dimethylpropyl)-benzamide
179116-92-8

(+)-(S)-2-fluoro-N-(2-hydroxymethyl-2,2-dimethylpropyl)-benzamide

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane for 1.5h;99%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

anthranilic acid nitrile
1885-29-6

anthranilic acid nitrile

2-[(4S)-4-(tert-butyl)-4,5-dihydro-1,3-oxazol-2-yl]aniline
194350-71-5

2-[(4S)-4-(tert-butyl)-4,5-dihydro-1,3-oxazol-2-yl]aniline

Conditions
ConditionsYield
With zinc(II) chloride In chlorobenzene for 24h; Inert atmosphere; Reflux;99%
With zinc(II) chloride In dichloromethane at 140℃; for 24h;85%
With zinc(II) chloride In chlorobenzene at 130℃; for 36h;82%
(E)-3-phenylpropenal
14371-10-9

(E)-3-phenylpropenal

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(S)-3,3-Dimethyl-2-[(E)-3-phenyl-prop-2-en-(E)-ylideneamino]-butan-1-ol

(S)-3,3-Dimethyl-2-[(E)-3-phenyl-prop-2-en-(E)-ylideneamino]-butan-1-ol

Conditions
ConditionsYield
In diethyl ether for 1.33333h; Ambient temperature;99%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

N-Boc-L-tert-leucinol
153645-26-2

N-Boc-L-tert-leucinol

Conditions
ConditionsYield
Stage #1: di-tert-butyl dicarbonate With molybdenium(VI) dioxodichloride In dichloromethane at 20℃; for 0.5h;
Stage #2: (S)-tert-leucinol In dichloromethane at 20℃; for 12h;
99%
With triethylamine In dichloromethane at 0 - 20℃; Acylation;93%
With iodine at 20℃; for 3h;92%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

2,2-dimethylpropanoic anhydride
1538-75-6

2,2-dimethylpropanoic anhydride

N-(1-hydroxymethyl-2,2-dimethyl-propyl)-2,2-dimethyl-propanamide
383149-98-2

N-(1-hydroxymethyl-2,2-dimethyl-propyl)-2,2-dimethyl-propanamide

Conditions
ConditionsYield
Stage #1: 2,2-dimethylpropanoic anhydride With molybdenium(VI) dioxodichloride In dichloromethane at 20℃; for 0.5h;
Stage #2: (S)-tert-leucinol In dichloromethane at 20℃; for 6h;
99%
With vanadyl triflate In dichloromethane at 20℃; for 15h;97%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

formic acid ethyl ester
109-94-4

formic acid ethyl ester

(+)-(2S)-(formylamino)-3,3-dimethyl-1-butanol
534601-53-1

(+)-(2S)-(formylamino)-3,3-dimethyl-1-butanol

Conditions
ConditionsYield
Reflux;99%
for 3h; Heating;89%
for 2h; Heating;
2-mesitylenesulphonyl chloride
773-64-8

2-mesitylenesulphonyl chloride

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

(2S)-N-(2,4,6-trimethylbenzenesulfonyl)-2-amino-3,3-dimethyl-butanol
678166-23-9

(2S)-N-(2,4,6-trimethylbenzenesulfonyl)-2-amino-3,3-dimethyl-butanol

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 18h;99%
With triethylamine In chloroform; N,N-dimethyl-formamide at 0℃; for 16h;94%
2,6-Pyridinedicarbonyl dichloride
3739-94-4

2,6-Pyridinedicarbonyl dichloride

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

N2,N6-bis((S)-1-hydroxy-3,3-dimethylbutan-2-yl)pyridine-2,6-dicarboxamide

N2,N6-bis((S)-1-hydroxy-3,3-dimethylbutan-2-yl)pyridine-2,6-dicarboxamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 16h;99%
With triethylamine In dichloromethane for 12h; Reflux;66%
In chloroform at 0℃;
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

acetic anhydride
108-24-7

acetic anhydride

N-(1-hydroxymethyl-2,2-dimethyl-propyl) acetamide

N-(1-hydroxymethyl-2,2-dimethyl-propyl) acetamide

Conditions
ConditionsYield
Stage #1: acetic anhydride With molybdenium(VI) dioxodichloride In dichloromethane at 20℃; for 0.5h;
Stage #2: (S)-tert-leucinol In dichloromethane at 20℃; for 2h;
99%
(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(S)-(+)-N-(1-hydroxymethyl-2,2-dimethylpropyl)-4-methylbenzenesulfonamide
887255-41-6

(S)-(+)-N-(1-hydroxymethyl-2,2-dimethylpropyl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0 - 25℃;99%
With triethylamine In dichloromethane at 0 - 20℃; for 18h;99%
With triethylamine In dichloromethane at 20℃; for 16h;

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