Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:115103-54-3
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
Cas:115103-54-3
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
CAS No: 115103-54-3 Synonyms: (R)-Tiagabine, Gabatril, HSDB 7527, NO 050328, NO 328, Tiagabina, Tiagabina [INN-Spanish], Tiagabine, Tiagabinum, Tiagabinum [INN-Latin], UNII-Z80I64HMNP ATC code
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:115103-54-3
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryStorage:under inert gas (nitrogen or Argon) at 2-8°C Package:25kg/Barrel Application:APIs Transportation:Express/Sea/Air Port:Any port in China
Cas:115103-54-3
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryTiagabine CAS:115103-54-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,
Cas:115103-54-3
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:115103-54-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Tiagabine cas 115103-54-3 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control syste
Cas:115103-54-3
Min.Order:1 Kilogram
FOB Price: $10.0 / 50.0
Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:115103-54-3
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Enterprice standard Application:Anti-cancer, anti-tumor drug
high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
best seller Application:API
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:115103-54-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryTiagabine Application:Tiagabine
Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
best seller Application:API
We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as pri
ethyl (R)-1-<4,4-bis(3-methyl-2-thienyl)-3-butenyl>-3-piperidinecarboxylate
tiagabine
Conditions | Yield |
---|---|
With hydrogenchloride In water | 90% |
With hydrogenchloride In water | 90% |
With hydrogenchloride In water | 86% |
With hydrogenchloride In water | 86% |
With sodium hydroxide In ethanol for 4h; Ambient temperature; |
tiagabine
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In water at 20℃; for 3h; Product distribution / selectivity; | |
With sodium hydroxide In water pH=6; Product distribution / selectivity; Aqueous phosphate buffer; Sonographic reaction; No light exposure; | |
Stage #1: tiagabine hydrochloride With sodium hydroxide In dichloromethane; water at 20℃; for 1 - 2.5h; Stage #2: With sodium hydrogencarbonate In dichloromethane; water at 20℃; for 1 - 2h; Product distribution / selectivity; |
2-bromo-3-methylthiophene
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 1.) Mg / 1.) Et2O, 1 h, 2.) Et2O, 1 h 2: 76 percent / MnO2 / CH2Cl2 / 16 h / Ambient temperature 3: 1.) Mg / 1.) THF, reflux, 0.5 h, 2.) THF, reflux, 1.5 h 4: 46 percent / 48percent aq. HBr / acetic acid / 1.5 h / 10 °C 5: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 6: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme | |
Multi-step reaction with 4 steps 1: 1.) n-BuLi / 1.) Et2O, 10 deg C, 15 min, 2.) Et2O, -70 deg C, 2.5 h 2: 20percent aq. H2SO4 / propan-2-ol / 3 h / Ambient temperature 3: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 4: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme | |
Multi-step reaction with 6 steps 1.1: magnesium / tetrahydrofuran / 1 h / 35 °C 1.2: 2 h / 0 °C / Reflux 2.1: hydrogenchloride / water; methanol / 1 °C / Reflux 3.1: triethylamine / diethyl ether / 1 h 4.1: potassium iodide; potassium carbonate / acetone / 120 h / 20 °C 5.1: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 6.1: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
3-methyl-2-thiophenecarboxaldehdye
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 1.) Mg / 1.) Et2O, 1 h, 2.) Et2O, 1 h 2: 76 percent / MnO2 / CH2Cl2 / 16 h / Ambient temperature 3: 1.) Mg / 1.) THF, reflux, 0.5 h, 2.) THF, reflux, 1.5 h 4: 46 percent / 48percent aq. HBr / acetic acid / 1.5 h / 10 °C 5: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 6: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme |
bis(3-methyl-2-thienyl)methanone
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 1.) Mg / 1.) THF, reflux, 0.5 h, 2.) THF, reflux, 1.5 h 2: 46 percent / 48percent aq. HBr / acetic acid / 1.5 h / 10 °C 3: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 4: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme |
bis(3-methyl-2-thienyl)methanol
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 76 percent / MnO2 / CH2Cl2 / 16 h / Ambient temperature 2: 1.) Mg / 1.) THF, reflux, 0.5 h, 2.) THF, reflux, 1.5 h 3: 46 percent / 48percent aq. HBr / acetic acid / 1.5 h / 10 °C 4: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 5: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme |
2-[4-bromo-1-(3-methylthien-2-yl)but-1-enyl]-3-methylthiophene
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 2: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme |
cyclopropylbis(3-methyl-2-thienyl)methanol
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 46 percent / 48percent aq. HBr / acetic acid / 1.5 h / 10 °C 2: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 3: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme |
4-Bromo-1,1-bis-(3-methyl-thiophen-2-yl)-butan-1-ol
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 20percent aq. H2SO4 / propan-2-ol / 3 h / Ambient temperature 2: 50 percent / KI, K2CO3 / acetone / 44 h / Ambient temperature 3: 12 M aq. NaOH / ethanol / 4 h / Ambient temperature View Scheme |
4,4-bis(3-methyl-2-thienyl)-3-buten-1-ol
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: triethylamine / diethyl ether / 1 h 2: potassium iodide; potassium carbonate / acetone / 120 h / 20 °C 3: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 4: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
tiagabine
Conditions | Yield |
---|---|
With C63H78IrNOP(2+)*C32H12BF24(1-); hydrogen In methanol at 60℃; under 4560.31 Torr; for 12h; Autoclave; enantioselective reaction; | n/a |
arecoline hydrobromide
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: potassium carbonate; water / 0.5 h / 20 °C 2: potassium iodide; potassium carbonate / acetone / 120 h / 20 °C 3: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 4: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
1-(1-chloroethyl) 3-methyl 5,6-dihydropyridine-1,3(2H)-dicarboxylate
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: methanol / 2 h / Reflux 1.2: 0.5 h 2.1: potassium iodide; potassium carbonate / acetone / 120 h / 20 °C 3.1: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 4.1: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
norarecoline
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: potassium iodide; potassium carbonate / acetone / 120 h / 20 °C 2: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 3: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
1,1-bis(3-methylthiophen-2-yl)butane-1,4-diol
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: hydrogenchloride / water; methanol / 1 °C / Reflux 2: triethylamine / diethyl ether / 1 h 3: potassium iodide; potassium carbonate / acetone / 120 h / 20 °C 4: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 5: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl methanesulfonate
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: potassium iodide; potassium carbonate / acetone / 120 h / 20 °C 2: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 3: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
tiagabine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium hydroxide / water; methanol / 2 h / 20 - 50 °C 2: hydrogen; C63H78IrNOP(2+)*C32H12BF24(1-) / methanol / 12 h / 60 °C / 4560.31 Torr / Autoclave View Scheme |
tiagabine
tiagabine hydrobromide
Conditions | Yield |
---|---|
With hydrogen bromide In di-isopropyl ether; ethyl acetate; acetonitrile at 20℃; Product distribution / selectivity; | 94% |
Conditions | Yield |
---|---|
In methanol; acetonitrile Product distribution / selectivity; | 91% |
In tetrahydrofuran; dichloromethane; isopropyl alcohol at 20℃; for 48h; Product distribution / selectivity; |
tiagabine
Conditions | Yield |
---|---|
With hydrogenchloride In dichloromethane; water at 20℃; for 1h; | 90% |
With hydrogenchloride In methanol; dichloromethane; chloroform at 3℃; for 24h; |
Conditions | Yield |
---|---|
In methanol; ethyl acetate; acetonitrile at 20℃; for 1h; Product distribution / selectivity; | 77% |
In tetrahydrofuran; dichloromethane; isopropyl alcohol at 20℃; for 48h; Product distribution / selectivity; |
Conditions | Yield |
---|---|
In methanol; acetonitrile Product distribution / selectivity; | 68% |
In methanol; dichloromethane at 20℃; for 48h; Product distribution / selectivity; |
Conditions | Yield |
---|---|
In methanol; ethyl acetate; acetonitrile at 20℃; for 1h; | 32% |
Conditions | Yield |
---|---|
In methanol; acetonitrile at 20℃; Product distribution / selectivity; | |
In dichloromethane; ethyl acetate; acetone at 20℃; for 48h; Product distribution / selectivity; |
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