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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 18Alpha-Glycyrrhetinic Acid supplier in China

Cas:1449-05-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Natural Extract 98% 18alpha-Glycyrrhetinic acid 1449-05-4 HACCP Manufacturer

Cas:1449-05-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM---18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

18alpha-Glycyrrhetinic acid CAS 1449-05-4

Cas:1449-05-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 1449-05-4 with competitive price

Cas:1449-05-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Appearance:white to off-white powder Storage:Store in dry、dark、ventilated place

High quality 18alpha-Glycyrrhetinic acid1449-05-4 (lower price)

Cas:1449-05-4

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:1 Kilogram

FOB Price: $60.0 / 65.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

18alpha-Glycyrrhetinic acid CAS:1449-05-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

18alpha-Glycyrrhetinic acid CAS:1449-05-4

Cas:1449-05-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

18alpha-Glycyrrhetinicacid

Cas:1449-05-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

18Alpha-Glycyrrhetinic Acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Luyunjia Chemistry Xiamen Limited

About us HK Luyunjia Chemical Industry Co.,Ltd is a high-tech company specializing in R&D and manufacturing of photoinitiators monomers and oligomers, UV absorbers and pharmaceutical intermediates, and pharmaceutical intermediates of generic dr

1449-05-4 18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detection

18alpha-Glycyrrhetinic acid Manufactuered in China high quality

Cas:1449-05-4

Min.Order:100 Gram

Negotiable

Type:Trading Company

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 18α-Glycyrrhetinic acid G51690 20mg

Cas:1449-05-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

18-alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

18Alpha-Glycyrrhetinic Acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE:1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day2. The products are provided with COA, HPLC, NMR, quality assurance, pac

18α-Glycyrrhetic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

18A-glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

18alpha-Glycyrrhetinic acid cas 1449-05-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

18alpha-Glycyrrhetinic acid cas 1449-05-4

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketing of chemicals. We have earned ourselves a good reputation at home an

18alpha-Glycyrrhetinic acid manufacture

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Asure Biochem CO.,LTD.

*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:1kg/tin 5kg/tin 25kg/carton Application:Pharmaceutical raw materials, making injection powder oral agent Tr

18α-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:20mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any por

Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

shanghai Tauto Biotech Co., Ltd

Appearance:powder or crystal Storage:-20degree Package:10mg,20mg,1g or on request Application:For research use only, like HPLC, Cell Culture, Animal Experiment, High Throughout Screening, etc.. Transportation:room temperature

18alpha-Glycyrrhetinic acid

Cas:1449-05-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

methyl 3-benzoyl-18α-glycyrrhetinate
650140-36-6

methyl 3-benzoyl-18α-glycyrrhetinate

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

Conditions
ConditionsYield
With sodium hydroxide In water; ethylene glycol; isopropyl alcohol for 2h; Heating;84%
18α-glycyrrhizic acid

18α-glycyrrhizic acid

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

Conditions
ConditionsYield
With hydrogenchloride In water; acetic acid at 100℃; for 1h;72%
enoxolone
471-53-4

enoxolone

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

Conditions
ConditionsYield
With potassium tert-butylate for 8h; Reagent/catalyst; Reflux;68.5%
With potassium hydroxide In diethylene glycol for 2h; Reflux;46%
With potassium hydroxide In diethylene glycol at 220℃; for 2h;45%
With potassium hydroxide In diethylene glycol at 100 - 220℃;43.7%
With hydrogenchloride; acetic acid
methyl 18α,b-glycyrrhetinate

methyl 18α,b-glycyrrhetinate

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

Conditions
ConditionsYield
With sodium hydroxide In water; ethylene glycol; isopropyl alcohol for 2h; Heating;20%
Multi-step reaction with 2 steps
1: pyridine / 14 h / 20 °C
2: 84 percent / sodium hydroxide / H2O; propan-2-ol; ethane-1,2-diol / 2 h / Heating
View Scheme
glycyrrhetinoic acid methyl ester

glycyrrhetinoic acid methyl ester

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

Conditions
ConditionsYield
With potassium hydroxide
18α-glycyrrhizic acid

18α-glycyrrhizic acid

A

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

B

glycyrrhetic acid 3-O-mono-β-D-glucuronide

glycyrrhetic acid 3-O-mono-β-D-glucuronide

Conditions
ConditionsYield
With β-glucuronidase Kinetics; Reagent/catalyst; Enzymatic reaction;
glycyrrhetic acid 3-O-mono-β-D-glucuronide

glycyrrhetic acid 3-O-mono-β-D-glucuronide

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

Conditions
ConditionsYield
With β-glucuronidase for 10h; Enzymatic reaction;
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

(3β,18α)-methyl 3-hydroxy-11-oxoolean-12-30-oate
5092-01-3

(3β,18α)-methyl 3-hydroxy-11-oxoolean-12-30-oate

Conditions
ConditionsYield
In diethyl ether100%
In diethyl ether; dichloromethane76.3%
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

methyl iodide
74-88-4

methyl iodide

(3β,18α)-methyl 3-hydroxy-11-oxoolean-12-30-oate
5092-01-3

(3β,18α)-methyl 3-hydroxy-11-oxoolean-12-30-oate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 2h;86%
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

diazodiphenylmethane
908093-98-1

diazodiphenylmethane

(3β,18α,20β)-3-hydroxy-11-oxoolean-12-en-29-oic acid diphenylmethyl ester
441759-67-7

(3β,18α,20β)-3-hydroxy-11-oxoolean-12-en-29-oic acid diphenylmethyl ester

Conditions
ConditionsYield
In methanol; diethyl ether at 45℃;84%
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

3,11-dioxo-18α-olean-12-en-30-oic acid
6184-16-3

3,11-dioxo-18α-olean-12-en-30-oic acid

Conditions
ConditionsYield
With chromium trioxide-pyridine complex In dichloromethane at 20℃; for 1h;80%
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

N-(3S-amino-2R-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitro-benzenesulfonamide hydrochloride
251105-80-3

N-(3S-amino-2R-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitro-benzenesulfonamide hydrochloride

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hydroxy-N-((2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitrophenylsulfonamido)-1-phenylbutan-2-yl)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hydroxy-N-((2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitrophenylsulfonamido)-1-phenylbutan-2-yl)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide

Conditions
ConditionsYield
Stage #1: 18-α-glycyrrhetinic acid; N-(3S-amino-2R-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitro-benzenesulfonamide hydrochloride With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 1.16667h; Inert atmosphere;
Stage #2: With dmap at 20℃; for 11h; Inert atmosphere;
69%
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide
159005-71-7

N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hydroxy-N-((2S,3R)-3-hydroxy-4-(N-isobutyl-4-methoxyphenylsulfonamido)-1-phenylbutan-2-yl)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hydroxy-N-((2S,3R)-3-hydroxy-4-(N-isobutyl-4-methoxyphenylsulfonamido)-1-phenylbutan-2-yl)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide

Conditions
ConditionsYield
Stage #1: 18-α-glycyrrhetinic acid; N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 1.16667h; Inert atmosphere;
Stage #2: With dmap at 20℃; for 11h; Inert atmosphere;
65%
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

4-amino-N-(2R,3S)(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
169280-56-2

4-amino-N-(2R,3S)(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-N-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-N-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide

Conditions
ConditionsYield
Stage #1: 18-α-glycyrrhetinic acid; 4-amino-N-(2R,3S)(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 1.16667h; Inert atmosphere;
Stage #2: With dmap at 20℃; for 11h; Inert atmosphere;
65%
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

(3β,18α)-methyl 3-hydroxy-11-oxoolean-12-30-oate
5092-01-3

(3β,18α)-methyl 3-hydroxy-11-oxoolean-12-30-oate

Conditions
ConditionsYield
With diazomethane; methanol; diethyl ether
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

acetic anhydride
108-24-7

acetic anhydride

3β-acetoxy-11-oxo-18α-oleanen-(12)-oic acid-(30)
18305-96-9

3β-acetoxy-11-oxo-18α-oleanen-(12)-oic acid-(30)

Conditions
ConditionsYield
With pyridine
succinic acid anhydride
108-30-5

succinic acid anhydride

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

Methyl 3-O-(β-carboxypropionyl)-18α-glycyrrhetat
17175-23-4

Methyl 3-O-(β-carboxypropionyl)-18α-glycyrrhetat

Conditions
ConditionsYield
(i) MeOH, Et2O, (ii) /BRN= 108441/, Py; Multistep reaction;
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

11-oxo-18α-olean-12-ene-3β,30-diol
60209-40-7

11-oxo-18α-olean-12-ene-3β,30-diol

Conditions
ConditionsYield
With manganese(IV) oxide; lithium aluminium tetrahydride 1.) THF, 60 deg C, 1 h, 2.) CHCl3, THF, 25 h; Yield given. Multistep reaction;
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

(18α)-methyl 3,11-dioxoolean-12-en-30-oate
6588-91-6

(18α)-methyl 3,11-dioxoolean-12-en-30-oate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / CrO3-Py / CH2Cl2 / 1 h / 20 °C
2: 100 percent / diethyl ether
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 25 °C
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

methyl β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-18α-glycyrrhetinate

methyl β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-18α-glycyrrhetinate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 31.1 percent / Ag2O; I2 / CHCl3 / 48 h / 20 °C
2: 405 mg / sodium methylate / CHCl3 / 1.5 h / -20 °C
3: 85 mg / H2 / 10 percent Pd/C / methanol / 20 °C / 2587.71 Torr
4: 65.5 percent / diethyl ether; methanol / 1 h
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-18α-glycyrrhetic acid
22596-24-3

β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-18α-glycyrrhetic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 31.1 percent / Ag2O; I2 / CHCl3 / 48 h / 20 °C
2: 405 mg / sodium methylate / CHCl3 / 1.5 h / -20 °C
3: 85 mg / H2 / 10 percent Pd/C / methanol / 20 °C / 2587.71 Torr
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

C55H76O14

C55H76O14

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 31.1 percent / Ag2O; I2 / CHCl3 / 48 h / 20 °C
2: 405 mg / sodium methylate / CHCl3 / 1.5 h / -20 °C
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

diphenylmethyl 2',3',6',2'',3'',4'',6''-heptaacetyl-β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-18α-glycyrrhetinate
441759-70-2

diphenylmethyl 2',3',6',2'',3'',4'',6''-heptaacetyl-β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-18α-glycyrrhetinate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 31.1 percent / Ag2O; I2 / CHCl3 / 48 h / 20 °C
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

(3β,18α)-methyl 3-acetoxy-11-oxoolean-12-en-30-oate
10301-82-3

(3β,18α)-methyl 3-acetoxy-11-oxoolean-12-en-30-oate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine
2: diazomethane; diethyl ether
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 25 °C
2: pyridine / dichloromethane / 2 h / 25 °C
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

A

(3α,18α)-methyl 3-amino-11-oxoolean-12-en-30-oate

(3α,18α)-methyl 3-amino-11-oxoolean-12-en-30-oate

B

(3β,18α)-methyl 3-amino-11-oxoolean-12-en-30-oate

(3β,18α)-methyl 3-amino-11-oxoolean-12-en-30-oate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 25 °C
3: ammonium acetate; sodium cyanoborohydride / methanol / 24 h / 25 °C
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

A

(3β)-methyl 3-acetoxy-13-carboxy-19-hydroxy-11-oxo-C-norolean-18-en-30-oate-12,19-lactone

(3β)-methyl 3-acetoxy-13-carboxy-19-hydroxy-11-oxo-C-norolean-18-en-30-oate-12,19-lactone

B

(3β,18β)-3-acetoxy-18-hydroxy-11-oxoolean-12-en-30-oic acid-30,18-lactone

(3β,18β)-3-acetoxy-18-hydroxy-11-oxoolean-12-en-30-oic acid-30,18-lactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 25 °C
2: pyridine / dichloromethane / 2 h / 25 °C
3: acetic acid; selenium(IV) oxide / 4 h / 145 °C / Microwave irradiation
View Scheme
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

3-ethoxycarbonyl-7-oxabicyclo[2.2.1]heptane-2-carbonyl chloride

3-ethoxycarbonyl-7-oxabicyclo[2.2.1]heptane-2-carbonyl chloride

3β-(2-formyl-7-oxabicyclo[2.2.1]heptane-3-carbethoxy)oxy-18α-glycyrrhetinic acid

3β-(2-formyl-7-oxabicyclo[2.2.1]heptane-3-carbethoxy)oxy-18α-glycyrrhetinic acid

Conditions
ConditionsYield
With dmap In dichloromethane for 10h; Reflux;
[2-(2,6-dichloroanilino)phenyl]acetic acid
15307-86-5

[2-(2,6-dichloroanilino)phenyl]acetic acid

18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

DC

DC

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 30℃;
18-α-glycyrrhetinic acid
1449-05-4

18-α-glycyrrhetinic acid

UDP-glucuronic acid
2616-64-0

UDP-glucuronic acid

18α-glycyrrhetinic acid 30-O-β-D-glucoside

18α-glycyrrhetinic acid 30-O-β-D-glucoside

Conditions
ConditionsYield
With recombinant Glycyrrhiza uralensis glycosyltransferase UGT73F17; magnesium(II) In aq. phosphate buffer at 45℃; for 12h; pH=7.5; regiospecific reaction;

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