Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
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inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
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inquiryUnique advantages of Etoricoxib Cas 202409-33-4 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Cool dry place Package:1kg/foill bag;25kg
Cas:202409-33-4
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inquiryEtoricoxib CAS No.:202409-33-4 Name: Etoricoxib Synonyms: 5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine Molecular Structure Molecular Formula: C18H15ClN2O2S Molecular Weight: 358.84 CA
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inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:202409-33-4
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:202409-33-4
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inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:202409-33-4
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:202409-33-4
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inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:202409-33-4
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inquiryItem Name Etoricoxib CAS NO. 202409-33-4 Apparence White Powder
Cas:202409-33-4
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inquiryAppearance:White to light yellow crystalline powder Storage:R.T Package:25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in China
Cas:202409-33-4
Min.Order:1 Kilogram
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inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryEtoricoxib CAS:202409-33-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates
Cas:202409-33-4
Min.Order:1 Gram
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,
Cas:202409-33-4
Min.Order:20 Metric Ton
Negotiable
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Our Advantage 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good qual
Cas:202409-33-4
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inquiryHangzhou Fandachem Co.,Ltd is China-based top1 exporter and supplier of Etoricoxib, Algix, Arcoxia, Etobrix, Etocox, CAS: 202409-33-4,please contact for price of Etoricoxib, Algix, Arcoxia, Etobrix, Etocox, CAS: 202409-33-4 and also you can sen
Cas:202409-33-4
Min.Order:25 Gram
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inquiryAppearance:white or yellowish white flaky crystal Storage:Keep the sun from direct sunlight ;prevention against high temperature Package:As customer request Application:Used for research and industrial manufacture. Transportatio
Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:202409-33-4
Min.Order:1 Gram
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:202409-33-4
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inquiryEtoricoxib cas 202409-33-4 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control syst
Cas:202409-33-4
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Etoricoxib CAS 202409-33-4 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 P
Cas:202409-33-4
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inquiryetoricoxib hydrochloride
etoricoxib
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In dichloromethane; water at 10 - 20℃; for 0.5h; Reagent/catalyst; Large scale; | 96.5% |
methyl iodide
etoricoxib
Conditions | Yield |
---|---|
Stage #1: 4-(5-chloro-6'-methyl-[2,3'-bipyridin]-3-yl)benzenesulfinic acid With tetra-(n-butyl)ammonium iodide In tetrahydrofuran at 65℃; for 0.333333h; Stage #2: methyl iodide In tetrahydrofuran at 65℃; for 2h; Cooling with liquid nitrogen; | 95% |
5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine
etoricoxib
Conditions | Yield |
---|---|
With sodium molybdate; sulfuric acid; dihydrogen peroxide In methanol at 55℃; for 0.25h; | 94% |
With oxygen; uranyl(VI) acetate dihydrate In o-xylene; water; acetonitrile at 20℃; under 760.051 Torr; Schlenk technique; Irradiation; | 91% |
With diethylene glycol dibutyl ether; oxygen at 110℃; for 20h; Green chemistry; | 78% |
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
With potassium hydroxide In acetonitrile at 80℃; for 8h; Concentration; Inert atmosphere; | 89% |
With caesium carbonate In tetrahydrofuran at 20℃; for 3h; | 82% |
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
Stage #1: 1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone With potassium tert-butylate In tetrahydrofuran at 0 - 20℃; for 0.25h; Inert atmosphere; Stage #2: N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate(V) With acetic acid In tetrahydrofuran at 20 - 25℃; for 2.5h; Inert atmosphere; Stage #3: With ammonium hydroxide In tetrahydrofuran at 60 - 65℃; for 1.5h; Inert atmosphere; | 84.4% |
With methanesulfonic acid; ammonium acetate; propionic acid In toluene at 25 - 75℃; for 14 - 16h; Reflux; |
2,5-dichloro-3-[4-(methylsulfonyl)phenyl]pyridine
etoricoxib
Conditions | Yield |
---|---|
palladium | 79% |
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
Stage #1: 1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone With potassium tert-butylate In tetrahydrofuran at 25 - 30℃; for 1h; Stage #2: 2-chloro-1,3-(bis-piperidinyl)trimethinium hexafluorophosphate In tetrahydrofuran at 30 - 55℃; Product distribution / selectivity; | 75.9% |
formamide
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
With methanesulfonic acid In 1,2-dichloro-ethane at 80 - 100℃; for 24h; | 73% |
etoricoxib
Conditions | Yield |
---|---|
With ammonium hydroxide In tetrahydrofuran at 60 - 65℃; Inert atmosphere; | 72.1% |
With ammonium hydroxide In tetrahydrofuran for 5h; cyclocondensation; Heating; |
(6-methylpyridin-3-yl)boronic acid
etoricoxib
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate In 1,4-dioxane; water at 80℃; for 8h; Suzuki Coupling; chemoselective reaction; | 71% |
5-bromo-2-methylpyridine
etoricoxib
Conditions | Yield |
---|---|
With di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate In 1,4-dioxane at 120℃; for 18h; Inert atmosphere; | 69% |
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
With methanesulfonic acid; propionic acid In toluene at 114℃; for 12h; Heating / reflux; | 65% |
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
A
3,5-dichloropyridine
B
etoricoxib
Conditions | Yield |
---|---|
With ammonium acetate In propionic acid at 125℃; | A n/a B 62% C 15% |
(6-methylpyridin-3-yl)boronic acid
etoricoxib
Conditions | Yield |
---|---|
With palladium diacetate; sodium hydrogencarbonate; tricyclohexylphosphine In 1,4-dioxane; water at 80℃; for 1.5h; Suzuki-Miyaura Coupling; Sealed tube; Inert atmosphere; Schlenk technique; | 60% |
With tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate In 1,4-dioxane; water at 80℃; for 3h; Inert atmosphere; Schlenk technique; Sealed tube; | 52% |
2,3-dichloroacrolein
etoricoxib
Conditions | Yield |
---|---|
Stage #1: 2,3-dichloroacrolein; Lithium; (Z)-2-(4-methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-ethenolate In tetrahydrofuran Stage #2: With ammonia In tetrahydrofuran Heating; Further stages.; | 58% |
2-bromo-5-chloro-3-(4-(methylsulfonyl)phenyl)pyridine
(6-methylpyridin-3-yl)boronic acid
etoricoxib
Conditions | Yield |
---|---|
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); cesium fluoride In 1,4-dioxane for 20h; Concentration; Suzuki Coupling; Inert atmosphere; Reflux; | 55% |
4-methanesulphonylphenylboronic acid
etoricoxib
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In 1,4-dioxane at 100℃; | 54% |
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
With ammonium acetate In propionic acid Heating; | 47% |
etoricoxib
Conditions | Yield |
---|---|
With ammonium hydroxide In tetrahydrofuran for 3h; Heating; | 8.42 g |
2-methyl-5-formylpyridine
etoricoxib
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 46.5 g / isopropyl acetate / 60 °C 2: 46.5 g / isopropyl acetate / 60 - 65 °C 3: t-BuOK / propan-2-ol; tetrahydrofuran / 0.5 h / 25 °C 4: 24.91 g / aq. HCl / 25 - 45 °C 5: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C 6: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C 7: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating View Scheme | |
Multi-step reaction with 5 steps 1: 46.5 g / isopropyl acetate / 60 °C 2: 46.5 g / isopropyl acetate / 60 - 65 °C 3: t-BuOK / propan-2-ol; tetrahydrofuran / 0.5 h / 25 °C 4: 24.91 g / aq. HCl / 25 - 45 °C 5: 62 percent / NH4OAc / propionic acid / 125 °C View Scheme | |
Multi-step reaction with 5 steps 1: 46.5 g / isopropyl acetate / 60 °C 2: 46.5 g / isopropyl acetate / 60 - 65 °C 3: t-BuOK / propan-2-ol; tetrahydrofuran / 0.5 h / 25 °C 4: 24.91 g / aq. HCl / 25 - 45 °C 5: 47 percent / NH4OAc / propionic acid / Heating View Scheme |
Methyl 6-methylnicotinate
etoricoxib
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 58 percent / t-BuMgCl / tetrahydrofuran / 50 °C 2: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C 3: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C 4: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: 58 percent / t-BuMgCl / tetrahydrofuran / 50 °C 2: 62 percent / NH4OAc / propionic acid / 125 °C View Scheme | |
Multi-step reaction with 2 steps 1: 58 percent / t-BuMgCl / tetrahydrofuran / 50 °C 2: 47 percent / NH4OAc / propionic acid / Heating View Scheme |
4-(methylsulfonyl)phenylacetic acid
etoricoxib
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 58 percent / t-BuMgCl / tetrahydrofuran / 50 °C 2: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C 3: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C 4: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: 58 percent / t-BuMgCl / tetrahydrofuran / 50 °C 2: 62 percent / NH4OAc / propionic acid / 125 °C View Scheme | |
Multi-step reaction with 2 steps 1: 58 percent / t-BuMgCl / tetrahydrofuran / 50 °C 2: 47 percent / NH4OAc / propionic acid / Heating View Scheme |
N-methoxy-N-methyl-6-methylnicotinamide
etoricoxib
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 80 percent / tetrahydrofuran; toluene / 1 h / -10 °C 2: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C 3: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C 4: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C 5: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating View Scheme | |
Multi-step reaction with 3 steps 1: 80 percent / tetrahydrofuran; toluene / 1 h / -10 °C 2: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C 3: 62 percent / NH4OAc / propionic acid / 125 °C View Scheme | |
Multi-step reaction with 3 steps 1: 80 percent / tetrahydrofuran; toluene / 1 h / -10 °C 2: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C 3: 47 percent / NH4OAc / propionic acid / Heating View Scheme |
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C 2: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C 3: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C 4: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C 2: 62 percent / NH4OAc / propionic acid / 125 °C View Scheme | |
Multi-step reaction with 2 steps 1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C 2: 47 percent / NH4OAc / propionic acid / Heating View Scheme |
1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
etoricoxib
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C 2: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C 3: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating View Scheme | |
Multi-step reaction with 3 steps 1: t-BuOK / tetrahydrofuran / 0.75 h / 25 °C 2: TFA; AcOH / tetrahydrofuran / 0.75 h / 25 - 30 °C 3: aq. NH3 / tetrahydrofuran / 5 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1.1: potassium tert-butylate / tetrahydrofuran / 30 - 55 °C / Large scale 1.2: Large scale 2.1: sodium hydroxide; water / 25 - 35 °C View Scheme |
etoricoxib
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 46.5 g / isopropyl acetate / 60 - 65 °C 2: t-BuOK / propan-2-ol; tetrahydrofuran / 0.5 h / 25 °C 3: 24.91 g / aq. HCl / 25 - 45 °C 4: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C 5: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C 6: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating View Scheme | |
Multi-step reaction with 4 steps 1: 46.5 g / isopropyl acetate / 60 - 65 °C 2: t-BuOK / propan-2-ol; tetrahydrofuran / 0.5 h / 25 °C 3: 24.91 g / aq. HCl / 25 - 45 °C 4: 62 percent / NH4OAc / propionic acid / 125 °C View Scheme | |
Multi-step reaction with 4 steps 1: 46.5 g / isopropyl acetate / 60 - 65 °C 2: t-BuOK / propan-2-ol; tetrahydrofuran / 0.5 h / 25 °C 3: 24.91 g / aq. HCl / 25 - 45 °C 4: 47 percent / NH4OAc / propionic acid / Heating View Scheme |
2-(1-cyclohexenyl)ethylamine
etoricoxib
Conditions | Yield |
---|---|
With C47H70BrO4PPdSi; sodium t-butanolate In tetrahydrofuran at 20℃; for 1h; Schlenk technique; Inert atmosphere; Sealed tube; | 97% |
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