Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

1-(6-Methylpyridin-3-yl)-2-[4-(methylthio)phenyl]ethanone

Cas:221615-72-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Purity: 98% up Storage:room temprature Package:25kg/drum Application:Etoricoxib intermediate Port:Beijing/Shanghai/Shenzhen/Hangzhou

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone, Etoricoxib Intermediate

Cas:221615-72-1

Min.Order:1 Kilogram

FOB Price: $320.0 / 400.0

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-(6-Methylpyridin-3-yl)-2-[4-(methylthio)-phenyl]-ethanone

Cas:221615-72-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Storage:Inert atmosphere,Room Temperature Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:shanghai

Cas no.221615-72-1 98% 1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM 1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 221615-72-1 with best quality

Cas:221615-72-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone CAS NO221615-72-1

Cas:221615-72-1

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Ethanone,1-(6-methyl-3-pyridinyl)-2-[4-(methylthio)phenyl]-

Cas:221615-72-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Ethanone,1-(6-methyl-3-pyridinyl)-2-[4-(methylthio)phenyl]-

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

high purity 1-(6-Methylpyridin-3-yl)-2-[4-(methylthio)phenyl]ethanone

Cas:221615-72-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Melting Point:111-113℃ Boiling Point:426.7±40.0 °C(Predicted) PKA:3.84±0.10(Predicted) PSA:55.26000 Density:1.17±0.1 g/cm3(Predicted) LogP:3.53730 Storage Temp.:Inert atmosphere,Room Temperature XLogP3:3 Hydr

221615-72-1 1-(6-Methylpyridin-3-yl)-2-(4-(methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:1 Gram

FOB Price: $6.0

Type:Trading Company

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

1-(6-Methylpyridin-3-yl)-2-(4-(methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/1-(6-Methylpyridin-3-yl)-2-[4-(methylthio)phenyl]ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Senova Technology Company Limited

1.High quality 2.High purity 3.Best price 4.Best service 5.Professional manufacturer 6.Loyal and honest supplier 7.Fast response to customer within 6 hours Application:Pharmaceutical Intermediate

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

1-(6-Methylpyridin-3-yl)-2-[4-(methylthio)phenyl]ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

1-(6-Methylpyridin-3-yl)-2-[4-(Methylthio)phenyl]ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Koning Pharmchem Co., Ltd.

KONING PHARMCHEM CO., LTD. has committed itself to a strategy of providing a unique service for companies involved in the manufacture of pharmaceuticals, healthcare products, food, cosmetics and other fine chemicals. Our products including but not li

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Ethanone,1-(6-methyl-3-pyridinyl)-2-[4-(methylthio)phenyl]-

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone

Cas:221615-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

Methyl 6-methylnicotinate
5470-70-2

Methyl 6-methylnicotinate

lithium 4-(methylthio)phenylacetate

lithium 4-(methylthio)phenylacetate

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
With tert-butylmagnesium chloride In tetrahydrofuran at 65 - 70℃; for 1h; Reagent/catalyst; Temperature;87.7%
N-methoxy-N-methyl-6-methylnicotinamide
221615-71-0

N-methoxy-N-methyl-6-methylnicotinamide

4-(methylthio)benzylmagnesium chloride

4-(methylthio)benzylmagnesium chloride

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
In tetrahydrofuran; toluene at -10℃; for 1h;80%
Methyl 6-methylnicotinate
5470-70-2

Methyl 6-methylnicotinate

sodium 4-(methylthio)phenylacetate

sodium 4-(methylthio)phenylacetate

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
With tert-butylmagnesium chloride In tetrahydrofuran at 65 - 70℃; for 1h;78.5%
1-(chloromethyl)-4-methylthiobenzene
874-87-3

1-(chloromethyl)-4-methylthiobenzene

N-methoxy-N-methyl-6-methylnicotinamide
221615-71-0

N-methoxy-N-methyl-6-methylnicotinamide

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
Stage #1: 1-(chloromethyl)-4-methylthiobenzene With magnesium In tetrahydrofuran; toluene for 3 - 4h;
Stage #2: N-methoxy-N-methyl-6-methylnicotinamide In toluene at -20℃; for 1.5h;
76%
With magnesium; ethylene dibromide In tetrahydrofuran; toluene at 36℃;62%
Methyl 6-methylnicotinate
5470-70-2

Methyl 6-methylnicotinate

2-(4-(methylthio)phenyl)acetic acid
16188-55-9

2-(4-(methylthio)phenyl)acetic acid

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
With tert-butylmagnesium chloride In tetrahydrofuran at 65 - 70℃; for 1h;72%
Stage #1: 2-(4-(methylthio)phenyl)acetic acid With tert-butylmagnesium chloride In tetrahydrofuran at 60℃; for 1h; Flow reactor;
Stage #2: Methyl 6-methylnicotinate In tetrahydrofuran at 60℃; for 1h; Flow reactor;
Stage #3: With hydrogenchloride In water; toluene Temperature; Flow reactor;
isoxazolidine-2-yl-(6-methylpyridin-3-yl)methanone

isoxazolidine-2-yl-(6-methylpyridin-3-yl)methanone

4-(methylthio)benzylmagnesium chloride

4-(methylthio)benzylmagnesium chloride

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
In tetrahydrofuran; toluene at -20 - -10℃; for 1h; Temperature; Inert atmosphere;60%
Methyl 6-methylnicotinate
5470-70-2

Methyl 6-methylnicotinate

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: i-PrMgCl / toluene; tetrahydrofuran / 0.5 h / -10 °C
2: 80 percent / tetrahydrofuran; toluene / 1 h / -10 °C
View Scheme
Multi-step reaction with 2 steps
1.1: toluene / 0.67 h / Reflux
1.2: Reflux
2.1: hydrogenchloride; water; acetic acid / 40 °C / Reflux
2.2: 0.17 h / 0 - 5 °C / pH 7 - 7.2
View Scheme
Multi-step reaction with 2 steps
1: sodium methylate / toluene / 0.67 h / 25 - 30 °C / pH 5.2-6.2 / Reflux
2: hydrogenchloride / toluene; water; acetic acid / 20 °C / pH 6.9-7.1
View Scheme
Multi-step reaction with 2 steps
1: isopropylmagnesium chloride / toluene; tetrahydrofuran / 0.5 h / -20 - -10 °C / Inert atmosphere
2: toluene; tetrahydrofuran / 1 h / -20 - -10 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: isopropylmagnesium chloride / toluene; tetrahydrofuran / 0.5 h / -20 - -10 °C / Inert atmosphere
2: diethyl ether / -10 - 0 °C
View Scheme
2-[4-(methylsulfanyl)phenyl]acetonitrile
38746-92-8

2-[4-(methylsulfanyl)phenyl]acetonitrile

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: toluene / 0.67 h / Reflux
1.2: Reflux
2.1: hydrogenchloride; water; acetic acid / 40 °C / Reflux
2.2: 0.17 h / 0 - 5 °C / pH 7 - 7.2
View Scheme
Multi-step reaction with 2 steps
1: sodium methylate / toluene / 0.67 h / 25 - 30 °C / pH 5.2-6.2 / Reflux
2: hydrogenchloride / toluene; water; acetic acid / 20 °C / pH 6.9-7.1
View Scheme
1-(6-methyl-3-pyridinyl)-2-cyano-2-[(4-methylthio)phenyl]ethanone
321913-54-6

1-(6-methyl-3-pyridinyl)-2-cyano-2-[(4-methylthio)phenyl]ethanone

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
Stage #1: 1-(6-methyl-3-pyridinyl)-2-cyano-2-[(4-methylthio)phenyl]ethanone With hydrogenchloride; water; acetic acid at 40℃; Reflux;
Stage #2: With ammonia In water at 0 - 5℃; for 0.166667h; pH=7 - 7.2; Product distribution / selectivity;
With hydrogenchloride In water; acetic acid; toluene at 20℃; pH=6.9-7.1; Concentration; Reagent/catalyst; Solvent; Time; Temperature;5.2 g
Methyl 6-methylnicotinate
5470-70-2

Methyl 6-methylnicotinate

2-[4-(methylsulfanyl)phenyl]acetonitrile
38746-92-8

2-[4-(methylsulfanyl)phenyl]acetonitrile

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
Stage #1: Methyl 6-methylnicotinate; 2-[4-(methylsulfanyl)phenyl]acetonitrile With hydrogenchloride; sodium methylate In water; toluene at 25 - 30℃; pH=5.2-6.2; Reflux;
Stage #2: With hydrogenchloride In water; acetic acid; toluene at 40 - 50℃; Reflux;
6-methyl-nicotinoyl chloride
51598-76-6

6-methyl-nicotinoyl chloride

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium hexamethyldisilazane / diethyl ether
2: toluene; tetrahydrofuran / 1 h / -20 - -10 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: sodium carbonate / water; dichloromethane / 0.5 h / 15 - 25 °C
2: diethyl ether / -10 - 0 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium carbonate / water; dichloromethane / 0.5 h / 15 - 25 °C
2: toluene; tetrahydrofuran / 1 h / -20 - -10 °C / Inert atmosphere
View Scheme
C8H9BrMgS

C8H9BrMgS

isoxazolidine-2-yl-(6-methylpyridin-3-yl)methanone

isoxazolidine-2-yl-(6-methylpyridin-3-yl)methanone

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

Conditions
ConditionsYield
In diethyl ether at -10 - 0℃; Temperature;
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone
221615-75-4

1-(6-methyl-3-pyridinyl)-2-[4-(methylsulfonyl)phenyl]ethanone

Conditions
ConditionsYield
Stage #1: 1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone With methanesulfonic acid; acetic acid at 5 - 10℃;
Stage #2: With dihydrogen peroxide at 5 - 25℃; for 6h;
97.5%
With sodium tungstate; dihydrogen peroxide In methanol at 40 - 50℃; for 2h; Temperature; Concentration;92%
With sodium tungstate; dihydrogen peroxide In methanol; sulfuric acid at 55℃;89%
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

(Z)-N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate

(Z)-N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate

5-chloro-6'-methyl-3-(4-methylsulfanyl-phenyl)-[2,3']bipyridinyl 1-oxide

5-chloro-6'-methyl-3-(4-methylsulfanyl-phenyl)-[2,3']bipyridinyl 1-oxide

Conditions
ConditionsYield
Stage #1: 1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone; (Z)-N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.75h;
Stage #2: With hydroxylamine hydrochloride; acetic acid; trifluoroacetic acid In tetrahydrofuran; water for 5h; Heating; Further stages.;
82%
vinamidinium hexafluorophosphate

vinamidinium hexafluorophosphate

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine
292067-97-1

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine

Conditions
ConditionsYield
Stage #1: 1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone With potassium tert-butylate In tetrahydrofuran at 20℃;
Stage #2: vinamidinium hexafluorophosphate With acetic acid; trifluoroacetic acid at 20℃;
Stage #3: With ammonium hydroxide for 6h; Heating;
74%
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

2-chloromalonaldehyde
50704-42-2

2-chloromalonaldehyde

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine
292067-97-1

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine

Conditions
ConditionsYield
With ammonium acetate; propionic acid at 130℃; for 16h; Temperature; Reagent/catalyst;68%
2-chloro-3-acetoxyacrolein
1447814-85-8

2-chloro-3-acetoxyacrolein

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine
292067-97-1

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine

Conditions
ConditionsYield
With ammonium acetate; propionic acid at 130℃; for 16h; Reagent/catalyst;45%
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

(Z)-N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate

(Z)-N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate

(Z)-4-Chloro-3,5-bis-dimethylamino-1-(6-methyl-pyridin-3-yl)-2-(4-methylsulfanyl-phenyl)-pent-4-en-1-one

(Z)-4-Chloro-3,5-bis-dimethylamino-1-(6-methyl-pyridin-3-yl)-2-(4-methylsulfanyl-phenyl)-pent-4-en-1-one

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 25℃; for 0.75h; Alkylation;
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

4-(5-chloro-6'-methyl-[2,3']bipyridinyl-3-yl)-benzenethiol

4-(5-chloro-6'-methyl-[2,3']bipyridinyl-3-yl)-benzenethiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: tBuOK / tetrahydrofuran / 20 °C
1.2: AcOH; TFA / 20 °C
1.3: 74 percent / aq. NH3 / 6 h / Heating
2.1: 84 percent / m-CPBA / CH2Cl2; H2O / 0.67 h / -20 °C
3.1: (CF3CO)2O; 2,6-lutidine / acetonitrile / 1 h / -10 °C
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

5-chloro-6'-methyl-3-(4-(methylsulfinyl)phenyl)-2,3'-bipyridine
316149-01-6, 745050-26-4, 745050-27-5

5-chloro-6'-methyl-3-(4-(methylsulfinyl)phenyl)-2,3'-bipyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tBuOK / tetrahydrofuran / 20 °C
1.2: AcOH; TFA / 20 °C
1.3: 74 percent / aq. NH3 / 6 h / Heating
2.1: 84 percent / m-CPBA / CH2Cl2; H2O / 0.67 h / -20 °C
View Scheme
Multi-step reaction with 4 steps
1: potassium tert-butylate / tetrahydrofuran / 20 °C
2: acetic acid; trifluoroacetic acid
3: ammonium hydroxide / water
4: uranyl(VI) acetate dihydrate; phosphoric acid; oxygen / water; acetonitrile / 12 h / 20 °C / 760.05 Torr / Schlenk technique; Irradiation
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

thiobutyric acid S-[4-(5-chloro-6'-methyl-[2,3']bipyridinyl-3-yl)phenyl] ester
866336-08-5

thiobutyric acid S-[4-(5-chloro-6'-methyl-[2,3']bipyridinyl-3-yl)phenyl] ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: tBuOK / tetrahydrofuran / 20 °C
1.2: AcOH; TFA / 20 °C
1.3: 74 percent / aq. NH3 / 6 h / Heating
2.1: 84 percent / m-CPBA / CH2Cl2; H2O / 0.67 h / -20 °C
3.1: (CF3CO)2O; 2,6-lutidine / acetonitrile / 1 h / -10 °C
4.1: 32 mg / pyridine / CH2Cl2 / 0.5 h / 0 - 20 °C
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

etoricoxib
202409-33-4

etoricoxib

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C
2: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C
3: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C
4: 8.42 g / aq. NH4OH / tetrahydrofuran / 3 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C
2: 62 percent / NH4OAc / propionic acid / 125 °C
View Scheme
Multi-step reaction with 2 steps
1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C
2: 47 percent / NH4OAc / propionic acid / Heating
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

(2Z,4Z)-4-Chloro-5-dimethylamino-2-(4-methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-penta-2,4-dien-1-one

(2Z,4Z)-4-Chloro-5-dimethylamino-2-(4-methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-penta-2,4-dien-1-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C
2: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C
3: AcOH; TFA / tetrahydrofuran / 0.75 h / 25 - 30 °C
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

(Z)-4-Chloro-3,5-bis-dimethylamino-2-(4-methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-pent-4-en-1-one

(Z)-4-Chloro-3,5-bis-dimethylamino-2-(4-methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-pent-4-en-1-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 89 percent / sodium tungstate; aq. H2O2 / aq. H2SO4; methanol / 55 °C
2: t-BuOK / tetrahydrofuran / 0.75 h / 20 °C
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine
292067-97-1

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: t-BuOK / tetrahydrofuran / 0.75 h / 25 °C
2: TFA; AcOH / tetrahydrofuran / 0.75 h / 25 - 30 °C
3: aq. NH3 / tetrahydrofuran / 5 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: potassium tert-butylate / tetrahydrofuran / 20 °C
2: acetic acid; trifluoroacetic acid
3: ammonium hydroxide / water
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

(2Z,4Z)-4-Chloro-5-dimethylamino-1-(6-methyl-pyridin-3-yl)-2-(4-methylsulfanyl-phenyl)-penta-2,4-dien-1-one

(2Z,4Z)-4-Chloro-5-dimethylamino-1-(6-methyl-pyridin-3-yl)-2-(4-methylsulfanyl-phenyl)-penta-2,4-dien-1-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: t-BuOK / tetrahydrofuran / 0.75 h / 25 °C
2: TFA; AcOH / tetrahydrofuran / 0.75 h / 25 - 30 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium tert-butylate / tetrahydrofuran / 20 °C
2: acetic acid; trifluoroacetic acid
View Scheme
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate(V)

N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate(V)

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine
292067-97-1

5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine

Conditions
ConditionsYield
Stage #1: 1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone With potassium tert-butylate In isopropyl alcohol at 5 - 8℃; for 4.5h;
Stage #2: N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate(V) In isopropyl alcohol at 5 - 8℃; Product distribution / selectivity;
Stage #1: 1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone With potassium tert-butylate In isopropyl alcohol at 5 - 8℃;
Stage #2: N-(2-chloro-3-(dimethylamino)allylidene)-N-methylmethanaminium hexafluorophosphate(V) In isopropyl alcohol
7.3 g
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone
221615-72-1

1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

5-chloro-3-(4-methylthiophenyl)-6'-methyl-[2,3']bipyridine hydrochloride
1447814-82-5

5-chloro-3-(4-methylthiophenyl)-6'-methyl-[2,3']bipyridine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: propionic acid; ammonium acetate / 16 h / 130 °C
2: hydrogenchloride / tert-butyl methyl ether
View Scheme
Multi-step reaction with 2 steps
1: propionic acid; ammonium acetate / 16 h / 130 °C
2: hydrogenchloride / tert-butyl methyl ether
View Scheme
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View