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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

4-Amino-2-chlorobenzoic acid Manufacturer/High quality/Best price/In stock

Cas:2457-76-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product description: Product name 4-Amino-2-chlorobenzoic acid CAS number 2457-76-3 Assay ≥99% Appearance Light yellow powder Capacity 200mt/year Application Pharmaceutical i

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Amino-2-Chlorobenzoic Acid

Cas:2457-76-3

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 4-Amino-2-Chlorobenzoic Acid 2457-76-3 GMP manufacturer

Cas:2457-76-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 2457-76-3 with best quality

Cas:2457-76-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White or almost white powder Storage:R.T Package:25kg/drum Application:Pharmaceutical intermediates Transportation:Express/Sea/Air Port:Any port in China

4-Amino-2-chlorobenzoicacid cas 2457-76-3

Cas:2457-76-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

Custom synthesis of high quality 4-amino-2-chlorobenzoic acid CAS 2457-76-3

Cas:2457-76-3

Min.Order:100 Gram

Negotiable

Type:Other

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Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

4-Amino-2-chlorobenzoic acid CAS:2457-76-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

4-Amino-2-chlorobenzoic acid CAS:2457-76-3

Cas:2457-76-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

4-Amino-2-chlorobenzoic acid CAS NO.2457-76-3

Cas:2457-76-3

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2457-76-3

Cas:2457-76-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Company information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in carbomer,carbopol,lead acetate,meglumine diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterpr

Factory Price 4-Amino-2-Chlorobenzoic Acid CAS 2457-76-3

Cas:2457-76-3

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Trading Company

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Amino-2-Chlorobenzoic Acid

Cas:2457-76-3

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Amino-2-Chlorobenzoic Acid

Cas:2457-76-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-amino-2-chlorobenzoicacid CAS NO.2457-76-3

Cas:2457-76-3

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and

TIANFU-CHEM CAS NO.2457-76-3 4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 2-Chloro-4-Amino Benzoic Acid CAS No.: 2457-76-3 Molecule Formula:C7H5ClNO2 Molecule Weight:170.57 Purity: 99.0% Package: 25kg/drum Description:White to off-white powder Manufacture Standards:Enterprise Standard TES

Lower Price 2-Chloro-4-Amino Benzoic Acid on stock

Cas:2457-76-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: 4-Amino-2-chlorobenzoic acid Synonyms: 2-Chloro-4-Aminobenzoic Acid CAS: 2457-76-3 MF: C7H5ClNO2 Appearance: White powder Storage:Store in cool and dry place, away from sun light. Package:25KG/Drum Application:Pharmaceutical Intermediate

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4-Amino-2-chlorobenzoicacid

Cas:2457-76-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2457-76-3 CAS NO.2457-76-3

Cas:2457-76-3

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Amino-2-Chlorobenzoic Acid cas no. 2457-76-3 98%

Cas:2457-76-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Amino-2-chlorobenzoic acid

Cas:2457-76-3

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

2-chloro-4-nitrobenzoic acid
99-60-5

2-chloro-4-nitrobenzoic acid

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate at 20℃; under 760 Torr;98%
With isopropyl alcohol; potassium hydroxide at 20℃; for 2.5h; Catalytic behavior;88%
With iron; ammonium chloride In ethanol; water for 2h; Reflux;24%
4-[bis((trimethylsilyl)ethoxymethyl)amino]-2-chlorobenzaldehyde

4-[bis((trimethylsilyl)ethoxymethyl)amino]-2-chlorobenzaldehyde

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
With Wilkinson's catalyst; hydrogen; dihydrogen peroxide at 20 - 70℃; under 3800.26 - 7600.51 Torr; for 13h; Temperature;93.6%
4-Acetylamino-2-chlorobenzoic acid
38667-55-9

4-Acetylamino-2-chlorobenzoic acid

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
With hydrogenchloride
2-chloro-4-nitrobenzoic acid
99-60-5

2-chloro-4-nitrobenzoic acid

ethyl acetate
141-78-6

ethyl acetate

palladium/barium sulfate

palladium/barium sulfate

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
Hydrogenation;
2-chloro-4-nitrotoluene
121-86-8

2-chloro-4-nitrotoluene

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous nitric acid / 120 - 180 °C
2: tin (II)-chloride; aqueous hydrochloric acid
View Scheme
Multi-step reaction with 4 steps
1: bromine / 130 - 135 °C
2: Pb(NO3)2; water
3: KMnO4
4: aqueous ammonia; iron sulfate(II) hydrate
View Scheme
Multi-step reaction with 2 steps
1: aqueous nitric acid / 120 - 180 °C
2: palladium; ethyl acetate / Hydrogenation
View Scheme
3-Chloroacetanilide
588-07-8

3-Chloroacetanilide

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: carbon disulfide; aluminium chloride
2: potassium permanganate; diluted sulfuric acid; magnesium sulfate
3: hydrochloric acid
View Scheme
acetic acid-(3-chloro-4-chloroacetyl-anilide)
90798-26-8

acetic acid-(3-chloro-4-chloroacetyl-anilide)

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium permanganate; diluted sulfuric acid; magnesium sulfate
2: hydrochloric acid
View Scheme
2-chloro-4-nitrobenzaldehyde
5568-33-2

2-chloro-4-nitrobenzaldehyde

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: KMnO4
2: aqueous ammonia; iron sulfate(II) hydrate
View Scheme
2-chloro-4-nitrobenzoyl chloride
7073-36-1

2-chloro-4-nitrobenzoyl chloride

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: KMnO4
2: aqueous ammonia; iron sulfate(II) hydrate
View Scheme
1-(bromomethyl)-2-chloro-4-nitrobenzene
42533-63-1

1-(bromomethyl)-2-chloro-4-nitrobenzene

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Pb(NO3)2; water
2: KMnO4
3: aqueous ammonia; iron sulfate(II) hydrate
View Scheme
6-chloro-2-fluoro-9-isopropyl-9H-purine
220696-58-2

6-chloro-2-fluoro-9-isopropyl-9H-purine

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-chloro-4-(2-fluoro-9-isopropyl-9H-purin-6-ylamino)benzoic acid
231951-16-9

2-chloro-4-(2-fluoro-9-isopropyl-9H-purin-6-ylamino)benzoic acid

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 80℃; for 12h;100%
methanol
67-56-1

methanol

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

methyl 4-amino-2-chlorobenzoate
46004-37-9

methyl 4-amino-2-chlorobenzoate

Conditions
ConditionsYield
With thionyl chloride at 0 - 20℃; for 32h;98%
With thionyl chloride at 0℃; Heating / reflux;97.4%
With acetyl chloride for 18h; Heating / reflux;97%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-choro-4-fluorobenzoic acid
2252-51-9

2-choro-4-fluorobenzoic acid

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With dihydrogen peroxide In water at 40 - 50℃; for 3h; Ionic liquid;
Stage #2: With potassium fluoride In water at 40 - 50℃; for 3h; Temperature;
97.5%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

acetyl chloride
75-36-5

acetyl chloride

methyl 4-amino-2-chlorobenzoate
46004-37-9

methyl 4-amino-2-chlorobenzoate

Conditions
ConditionsYield
In methanol for 18h; Heating / reflux;97%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

1,1'-Thiocarbonyldiimidazole
6160-65-2

1,1'-Thiocarbonyldiimidazole

4-isothiocyanato-2-chlorobenzoic acid
486415-44-5

4-isothiocyanato-2-chlorobenzoic acid

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid; 1,1'-Thiocarbonyldiimidazole With triethylamine In dichloromethane at 10℃; for 1h; Cooling with ice;
Stage #2: With hydrogenchloride In dichloromethane; water at 10℃; for 1h; Cooling with ice;
91%
thiocarbonyldiimidazole

thiocarbonyldiimidazole

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-isothiocyanato-2-chlorobenzoic acid
486415-44-5

4-isothiocyanato-2-chlorobenzoic acid

Conditions
ConditionsYield
Stage #1: thiocarbonyldiimidazole; 4-amino-2-chlorobenzoic acid With triethylamine In dichloromethane at 0 - 10℃; for 1h; Cooling with ice;
Stage #2: With hydrogenchloride In dichloromethane; water at 10℃; for 1h;
91%
chloral hydrate
302-17-0

chloral hydrate

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-chloro-4-[(-2-(hydroxyimino)ethanoyl)amino]benzoic acid

2-chloro-4-[(-2-(hydroxyimino)ethanoyl)amino]benzoic acid

Conditions
ConditionsYield
With hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate In water for 0.333333h; Heating / reflux;90%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

C12H7F3N4O2S

C12H7F3N4O2S

2-chloro-4-(3-(6-(trifluoromethoxy)benzo[d]thiazol-2-yl)ureido)benzoic acid

2-chloro-4-(3-(6-(trifluoromethoxy)benzo[d]thiazol-2-yl)ureido)benzoic acid

Conditions
ConditionsYield
In acetonitrile for 20h; Reflux;90%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

methylamine
74-89-5

methylamine

2-chloro-4-amino-N-methyl benzamide

2-chloro-4-amino-N-methyl benzamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In tetrahydrofuran; N,N-dimethyl-formamide at 20℃; for 48h;84%
C11H7ClN4OS
1353531-00-6

C11H7ClN4OS

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-chloro-4-(3-(6-chlorobenzo[d]thiazol-2-yl)ureido)benzoic acid

2-chloro-4-(3-(6-chlorobenzo[d]thiazol-2-yl)ureido)benzoic acid

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 20℃;83%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

Allyl chloroformate
2937-50-0

Allyl chloroformate

4-(((allyloxy)carbonyl)amino)-2-chlorobenzoic acid

4-(((allyloxy)carbonyl)amino)-2-chlorobenzoic acid

Conditions
ConditionsYield
With sodium carbonate; N-ethyl-N,N-diisopropylamine In 1,4-dioxane; water at 0℃; for 16h;83%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-amino-2-chloro-benzamide
211374-81-1

4-amino-2-chloro-benzamide

Conditions
ConditionsYield
With ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In DMF (N,N-dimethyl-formamide) at 20℃;79%
Octanal
124-13-0

Octanal

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-(octylamino)-2-chlorobenzoic acid
1344028-88-1

4-(octylamino)-2-chlorobenzoic acid

Conditions
ConditionsYield
With α-picoline-borane In methanol at 20℃;78%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-(4-(8-chloroimidazo[1,2-a]pyrazin-3-yl)-2,3-difluorophenoxyl)propanenitrile

2-(4-(8-chloroimidazo[1,2-a]pyrazin-3-yl)-2,3-difluorophenoxyl)propanenitrile

2-chloro-4-((3-(4-(1-cyanoethoxyl)-2,3-difluorophenyl)imidazo[1,2-a]pyrazin-8-yl)amino)benzoic acid

2-chloro-4-((3-(4-(1-cyanoethoxyl)-2,3-difluorophenyl)imidazo[1,2-a]pyrazin-8-yl)amino)benzoic acid

Conditions
ConditionsYield
With acetic acid In acetonitrile at 90℃; for 15h;75.5%
With acetic acid In acetonitrile at 90℃; for 15h; Inert atmosphere;75.5%
With acetic acid In acetonitrile at 90℃; for 15h;75.5%
With acetic acid In acetonitrile at 90℃; for 15h;530 mg
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(4-Amino-2-chlorophenyl)benzothiazole
43088-00-2

2-(4-Amino-2-chlorophenyl)benzothiazole

Conditions
ConditionsYield
With polyphosphoric acid for 0.5h; Microwave irradiation;75%
With PPA at 140℃; for 24h;
With PPA at 185℃;
C7H4ClN2O2(1+)
63468-61-1

C7H4ClN2O2(1+)

BrH*C7H6ClNO2

BrH*C7H6ClNO2

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-Bromo-2-chloro-benzoic Acid
59748-90-2

4-Bromo-2-chloro-benzoic Acid

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With hydrogen bromide In water at 120℃; for 1h;
Stage #2: BrH*C7H6ClNO2 With sodium nitrite In water at 5℃;
Stage #3: C7H4ClN2O2(1+) With hydrogen bromide; copper(I) bromide In water at 0℃; Heating / reflux;
73%
o-phenylbenzoyl chloride
14002-52-9

o-phenylbenzoyl chloride

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-[([1,1'-Biphenyl]-2-carbonyl)amino]-2-chlorobenzoic Acid

4-[([1,1'-Biphenyl]-2-carbonyl)amino]-2-chlorobenzoic Acid

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With pyridine; chloro-trimethyl-silane In toluene at 5℃; for 0.5h;
Stage #2: o-phenylbenzoyl chloride In toluene at 5℃; for 2.5h;
Stage #3: With hydrogenchloride; water In ethanol at 35 - 85℃;
69%
Stage #1: 4-amino-2-chlorobenzoic acid With pyridine In toluene at 20℃; for 0.25h;
Stage #2: With chloro-trimethyl-silane In toluene at 5℃; for 0.5h;
Stage #3: o-phenylbenzoyl chloride With hydrogenchloride; ethanol; water more than 3 stages;
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-(carbomethoxy)thiophene-3-sulfonyl chloride
59337-92-7

2-(carbomethoxy)thiophene-3-sulfonyl chloride

3-(4-carboxy-3-chlorophenylsulfamoyl)thiophene-2-carboxylic acid methyl ester

3-(4-carboxy-3-chlorophenylsulfamoyl)thiophene-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With pyridine at 50℃; for 24h;68%
(Z)-3-chloro-N'-hydroxy-4-isopropoxybenzimidamide
1035216-81-9, 1035218-35-9

(Z)-3-chloro-N'-hydroxy-4-isopropoxybenzimidamide

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

3-chloro-4-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)aniline
1035214-68-6

3-chloro-4-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)aniline

Conditions
ConditionsYield
With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide In acetonitrile at 120℃; for 0.5h; microwave irradiation;67.1%
With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide In acetonitrile at 120℃; for 0.5h; Microwave irradiation;
N,N'-bis(dimethylaminomethylene)hydrazine
16114-05-9

N,N'-bis(dimethylaminomethylene)hydrazine

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-chloro-4-(4H-1,2,4-triazol-4-yl)benzoic acid

2-chloro-4-(4H-1,2,4-triazol-4-yl)benzoic acid

Conditions
ConditionsYield
With trifluoroacetic anhydride In toluene for 8h; Reflux;64%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

methyl 4-amino-2-chlorobenzoate
46004-37-9

methyl 4-amino-2-chlorobenzoate

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With lithium hydroxide In tetrahydrofuran at 20℃; for 0.333333h;
Stage #2: dimethyl sulfate In tetrahydrofuran for 2h; Heating / reflux;
62%
isonipecotic acid methyl ester
2971-79-1

isonipecotic acid methyl ester

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

methyl 1-(4-amino-2-chlorobenzoyl)piperidine-4-carboxylate

methyl 1-(4-amino-2-chlorobenzoyl)piperidine-4-carboxylate

Conditions
ConditionsYield
Stage #1: isonipecotic acid methyl ester; 4-amino-2-chlorobenzoic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 0.5h; Inert atmosphere;
Stage #2: With HATU In dichloromethane for 10h; Inert atmosphere;
61.3%
Stage #1: isonipecotic acid methyl ester; 4-amino-2-chlorobenzoic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 0.5h;
Stage #2: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane for 10h;
61.3%
Stage #1: isonipecotic acid methyl ester; 4-amino-2-chlorobenzoic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 0.5h; Inert atmosphere;
Stage #2: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane for 10h;
61.3%
Stage #1: isonipecotic acid methyl ester; 4-amino-2-chlorobenzoic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 0.5h;
Stage #2: With HATU In dichloromethane for 10h;
61.3%
Stage #1: isonipecotic acid methyl ester; 4-amino-2-chlorobenzoic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 0.5h;
Stage #2: With HATU In dichloromethane for 10h;
61.3%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-chloro-4-hydrazinobenzoic acid hydrochloride

2-chloro-4-hydrazinobenzoic acid hydrochloride

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With hydrogenchloride; sodium nitrate for 0.5h; cooling;
Stage #2: With hydrogenchloride; tin(ll) chloride at 5℃; for 1h;
57%
Stage #1: 4-amino-2-chlorobenzoic acid With hydrogenchloride; sodium nitrite In water at 0℃; for 5.08333h;
Stage #2: With hydrogenchloride; tin(ll) chloride In water at 0 - 20℃; for 64h;
Stage #1: 4-amino-2-chlorobenzoic acid With hydrogenchloride In water for 0.5h; Cooling with ice;
Stage #2: With sodium nitrite In water for 1h; Cooling;
Stage #3: With hydrogenchloride; tin(II) chloride hydrate In water at 20℃;
Stage #1: 4-amino-2-chlorobenzoic acid With hydrogenchloride; sodium nitrite In water at 0℃; for 1h;
Stage #2: With hydrogenchloride; tin(ll) chloride In water at 0 - 20℃;
hexamethylene imine
111-49-9

hexamethylene imine

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-(azepan-1-ylcarbonyl)-3-chloroaniline
524955-73-5

4-(azepan-1-ylcarbonyl)-3-chloroaniline

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 3h;57%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-amino-2-chloro-benzyl alcohol
51420-25-8

4-amino-2-chloro-benzyl alcohol

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; Heating / reflux;
Stage #2: With sodium hydroxide In tetrahydrofuran; water at 0 - 20℃; for 1h;
56%
Allyl acetate
591-87-7

Allyl acetate

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

acetic acid 3-(4-carboxy-3-chloro-phenyl)-2-(4-carboxy-3-chloro-phenylazo)-propyl ester

acetic acid 3-(4-carboxy-3-chloro-phenyl)-2-(4-carboxy-3-chloro-phenylazo)-propyl ester

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With sulfuric acid; sodium nitrite In water at 0℃;
Stage #2: Allyl acetate With titanium(III) chloride; iron(II) sulfate In methanol; water at 0℃; for 0.5h;
55%
Stage #1: 4-amino-2-chlorobenzoic acid With sulfuric acid; sodium nitrite In water at 0℃;
Stage #2: Allyl acetate With iron(II) sulfate; titanium(III) chloride In methanol; water at 0℃; for 0.5h;
55%
1-[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]-methylamine
440087-51-4

1-[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]-methylamine

4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

4-amino-2-chloro-N-[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]benzamide
1445797-07-8

4-amino-2-chloro-N-[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]benzamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 16h;41%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-chloro-4-(chlorosulfonyl)benzoic acid
61953-04-6

2-chloro-4-(chlorosulfonyl)benzoic acid

Conditions
ConditionsYield
Stage #1: 4-amino-2-chlorobenzoic acid With hydrogenchloride; sodium nitrite In water; acetic acid at -10 - -5℃; for 1h;
Stage #2: With sulfur dioxide; copper(l) chloride In acetic acid at 0 - 10℃; for 0.5h;
34%

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