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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 10H-pyrido[3,2-b](1,4)benzothiazine

Cas:261-96-1

Min.Order:1

Negotiable

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 261-96-1 with competitive price

Cas:261-96-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 10H-pyrido(3,2-b)(1,4)benzothiazine Synonyms: PYRIDO[3,2-B][1,4]BENZOTHIAZINE;1-Azaphenothiazine;1H-Pyrido[3,2-b][1,4]benzothiazine;10H-pyrido(3,2-b)(1,4)benzothiazine;10H-benzo[e]pyrido[3,2-b][1;NSC 277720;10H-Benzo[b]pyrido[2,3-

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

10H-pyrido(3,2-b)(1,4)benzothiazine CAS:261-96-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

10H-pyrido(3,2-b)(1,4)benzothiazine CAS:261-96-1

Cas:261-96-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

261-96-1 10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:1 Kilogram

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

10H-Pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 10H-Benzo[b]pyrido[2,3-e][1,4]thiazine 10g

Cas:261-96-1

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

10H-pyrido(3,2-b)(1,4)benzothiazine CAS No.261-96-1

Cas:261-96-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our?company?has?been?in?existence?for?1581?years?since?its?establishment.?We?have?our?own?unique?team.?The??company?integrates?independent?research?and?development,?production?and?sales.?We?have?established?famous??brands?at?home?and?abroad.?At?prese

10H-Benzo[b]pyrido[2,3-e][1,4]thiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

10H-Pyrido[3,2-b][1,4]benzothiazine cas 261-96-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

10H-Pyrido[3,2-b][1,4]benzothiazine cas 261-96-1

Cas:261-96-1

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

Trimeric sodium phosphate detergent auxiliary agent is a kind of excellent properties, is one of the biggest component of detergent consumption during the production, it has four aspects: 1, chelation of heavy metal ions, heavy metal ions in the wate

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

261-96-1 Application:intermediate

10H-Pyrido[3,2-b][1,4]benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

10H-benzo[e]pyrido[3,2-b][1,4]thiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

261-96-1

Cas:261-96-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica

10H-Pyrido(3,2-b)(1,4)benzothiazine manufacturer

Cas:261-96-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

10H-pyrido(3,2-b)(1,4)benzothiazine

Cas:261-96-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

10-acetyl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine
95873-97-5

10-acetyl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 70℃; for 12h; Inert atmosphere;86%
With hydrogenchloride
N-(2-Mercaptophenyl)-2-pyridinamin

N-(2-Mercaptophenyl)-2-pyridinamin

A

2-Methylbenzothiazole
120-75-2

2-Methylbenzothiazole

B

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
With iodine In diphenylether; biphenyl at 200 - 205℃; for 2.5h;A n/a
B 45%
2,3-dibromopyridine
13534-89-9

2,3-dibromopyridine

2-amino-benzthiazole
136-95-8

2-amino-benzthiazole

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate In dimethyl sulfoxide at 170℃; for 24h; Inert atmosphere;39%
2,3-dibromopyridine
13534-89-9

2,3-dibromopyridine

N-(2-mercaptophenyl) acetamide
1444-47-9

N-(2-mercaptophenyl) acetamide

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
With 1,10-Phenanthroline; potassium tert-butylate In N,N-dimethyl-formamide at 135℃;25%
2-(phenylamino)pyridine
6631-37-4

2-(phenylamino)pyridine

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
With iodine; sulfur at 160 - 180℃;
With iodine; sulfur at 250 - 335℃;
With sulfur
With iodine; sulfur In water at 190℃; for 0.333333h; microwave irradiation;
iodine
7553-56-2

iodine

2-(phenylamino)pyridine
6631-37-4

2-(phenylamino)pyridine

sulfur

sulfur

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
at 160 - 180℃;
2-aminopyridine
504-29-0

2-aminopyridine

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K3PO4; X-phos / Pd2dba3 / toluene / 20 h / Heating
2: sulfur; I2 / H2O / 0.33 h / 190 °C / microwave irradiation
View Scheme
bromobenzene
108-86-1

bromobenzene

potassium hexacyanoferrate (II)

potassium hexacyanoferrate (II)

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K3PO4; X-phos / Pd2dba3 / toluene / 20 h / Heating
2: sulfur; I2 / H2O / 0.33 h / 190 °C / microwave irradiation
View Scheme
2-<(2-aminophenyl)thio>-3-nitropyridine
92316-06-8

2-<(2-aminophenyl)thio>-3-nitropyridine

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
2: aq.-ethanolic KOH
3: aq.-ethanolic HCl
View Scheme
Multi-step reaction with 2 steps
1: 20 °C
2: potassium hydroxide / acetone / Reflux
View Scheme
2-acetylaminophenyl-(3-nitro-2-pyridyl)sulfide
91902-18-0

2-acetylaminophenyl-(3-nitro-2-pyridyl)sulfide

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq.-ethanolic KOH
2: aq.-ethanolic HCl
View Scheme
With potassium hydroxide In acetone Smiles Aromatic Rearrangement; Reflux;
2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

1-azaphenothiazine
261-96-1

1-azaphenothiazine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: methanol; ethanol; KOH-solution / anschliessenden Erwaermen mit 2-Chlor-3-nitro-pyridin
3: aq.-ethanolic KOH
4: aq.-ethanolic HCl
View Scheme
chloropropionic acid
107-94-8

chloropropionic acid

1-azaphenothiazine
261-96-1

1-azaphenothiazine

10-(3-chloropropyl)-10H-benzo[b]pyrido[2,3-e][1,4]thiazine hydrochloride

10-(3-chloropropyl)-10H-benzo[b]pyrido[2,3-e][1,4]thiazine hydrochloride

Conditions
ConditionsYield
Stage #1: chloropropionic acid With sodium tetrahydroborate In toluene at 0 - 5℃;
Stage #2: 1-azaphenothiazine With sodium tetrahydroborate In toluene at 25 - 75℃; for 6h;
Stage #3: With hydrogenchloride In water; isopropyl alcohol
98%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

3-dimethylaminopropionic acid
6300-04-5

3-dimethylaminopropionic acid

Prothipendyl hydrochloride
1225-65-6

Prothipendyl hydrochloride

Conditions
ConditionsYield
Stage #1: 3-dimethylaminopropionic acid With sodium tetrahydroborate In toluene at 0 - 5℃;
Stage #2: 1-azaphenothiazine With sodium tetrahydroborate In toluene at 25 - 75℃; for 6h;
Stage #3: With hydrogenchloride In water; isopropyl alcohol
96%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

2-(4'-bromobiphenyl-4-yl)-4,6-diphenylpyrimidine

2-(4'-bromobiphenyl-4-yl)-4,6-diphenylpyrimidine

C39H26N4S

C39H26N4S

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene for 24h; Inert atmosphere; Reflux;80%
2-chloropyrazin
14508-49-7

2-chloropyrazin

1-azaphenothiazine
261-96-1

1-azaphenothiazine

10-Pyrazin-2-yl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine
89480-07-9

10-Pyrazin-2-yl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

Conditions
ConditionsYield
With copper; potassium carbonate; potassium iodide at 230 - 250℃; for 96h;77%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

2-(4’-bromo-[1,1‘-biphenyl]-4-yl)-4,6-diphenyl-1,3,5-triazine

2-(4’-bromo-[1,1‘-biphenyl]-4-yl)-4,6-diphenyl-1,3,5-triazine

C38H25N5S

C38H25N5S

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene for 24h; Inert atmosphere; Reflux;75%
2-Chloroquinoline
612-62-4

2-Chloroquinoline

1-azaphenothiazine
261-96-1

1-azaphenothiazine

10-Quinolin-2-yl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine
89480-08-0

10-Quinolin-2-yl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

Conditions
ConditionsYield
With copper; potassium carbonate; potassium iodide at 230 - 250℃; for 96h;73%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

tert-butyl 4-(4-bromophenoxy)piperidine-1-carboxylate
308386-38-1

tert-butyl 4-(4-bromophenoxy)piperidine-1-carboxylate

C27H29N3O3S
1206478-95-6

C27H29N3O3S

Conditions
ConditionsYield
With potassium carbonate; copper(l) iodide In N,N-dimethyl-formamide at 140℃; for 18h; sealed pressure tube;72%
1 ,6-dibromohexane
629-03-8

1 ,6-dibromohexane

1-azaphenothiazine
261-96-1

1-azaphenothiazine

1,6-bis(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)hexane
1421278-69-4

1,6-bis(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)hexane

Conditions
ConditionsYield
Stage #1: 1-azaphenothiazine With sodium hydride In N,N-dimethyl-formamide at -5℃; Inert atmosphere;
Stage #2: 1 ,6-dibromohexane In N,N-dimethyl-formamide at -5 - 20℃; Inert atmosphere;
71%
1,4-dibromo-butane
110-52-1

1,4-dibromo-butane

1-azaphenothiazine
261-96-1

1-azaphenothiazine

1,4-bis(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)butane
1421278-73-0

1,4-bis(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)butane

Conditions
ConditionsYield
Stage #1: 1-azaphenothiazine With sodium hydride In N,N-dimethyl-formamide at -5℃; Inert atmosphere;
Stage #2: 1,4-dibromo-butane In N,N-dimethyl-formamide at -5 - 20℃; Inert atmosphere;
70%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

(E)-1,4-dibromobutene
821-06-7

(E)-1,4-dibromobutene

1,4-bis(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)but-2E-ene
1421278-77-4

1,4-bis(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)but-2E-ene

Conditions
ConditionsYield
Stage #1: 1-azaphenothiazine With sodium hydride In N,N-dimethyl-formamide at -5℃; Inert atmosphere;
Stage #2: (E)-1,4-dibromobutene In N,N-dimethyl-formamide at -5 - 20℃; Inert atmosphere;
68%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

2-(3'-chloro-[1,1'-biphenyl]-3-yl)-4,6-diphenyl-1,3,5-triazine

2-(3'-chloro-[1,1'-biphenyl]-3-yl)-4,6-diphenyl-1,3,5-triazine

C38H25N5S

C38H25N5S

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene for 24h; Inert atmosphere; Reflux;68%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

2-(3′-chloro-[1,1′-biphenyl]-3-yl)-4,6-diphenylpyrimidine

2-(3′-chloro-[1,1′-biphenyl]-3-yl)-4,6-diphenylpyrimidine

C39H26N4S

C39H26N4S

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene for 24h; Inert atmosphere; Reflux;67%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

methyl 4-[(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)methyl]benzoate

methyl 4-[(10H-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl)methyl]benzoate

Conditions
ConditionsYield
Stage #1: 1-azaphenothiazine With lithium hexamethyldisilazane In N,N-dimethyl-formamide; toluene at 0℃; for 0.25h; Inert atmosphere;
Stage #2: Methyl 4-(bromomethyl)benzoate In N,N-dimethyl-formamide; toluene at 0 - 20℃; for 24h; Inert atmosphere;
67%
2-chloropyridine
109-09-1

2-chloropyridine

1-azaphenothiazine
261-96-1

1-azaphenothiazine

10-(2'-pyridyl)pyrido<3,2-b><1,4>benzothiazine
89480-06-8

10-(2'-pyridyl)pyrido<3,2-b><1,4>benzothiazine

Conditions
ConditionsYield
With copper; potassium carbonate; potassium iodide at 230 - 250℃; for 96h;65%
2-[(6-bromohexyl)oxy]tetrahydro-2H-pyran
53963-10-3

2-[(6-bromohexyl)oxy]tetrahydro-2H-pyran

1-azaphenothiazine
261-96-1

1-azaphenothiazine

10-(6-(tetrahydro-2H-pyran-2-yloxy)hexyl)-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

10-(6-(tetrahydro-2H-pyran-2-yloxy)hexyl)-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

Conditions
ConditionsYield
Stage #1: 1-azaphenothiazine With sodium hydride In N,N-dimethyl-formamide at -5 - 0℃; for 0.5h; Inert atmosphere;
Stage #2: 2-[(6-bromohexyl)oxy]tetrahydro-2H-pyran In N,N-dimethyl-formamide at 20℃; for 14h; Inert atmosphere;
61%
1-azaphenothiazine
261-96-1

1-azaphenothiazine

3-fluoro-4-methoxybenzyl bromide
331-61-3

3-fluoro-4-methoxybenzyl bromide

10-(3-fluoro-4-methoxybenzyl)-10H-pyrido[3,2-b][1,4]benzothiazine

10-(3-fluoro-4-methoxybenzyl)-10H-pyrido[3,2-b][1,4]benzothiazine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 24h; Inert atmosphere;61%
1 ,6-dibromohexane
629-03-8

1 ,6-dibromohexane

1-azaphenothiazine
261-96-1

1-azaphenothiazine

10-(6-bromohexyl)-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

10-(6-bromohexyl)-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

Conditions
ConditionsYield
Stage #1: 1-azaphenothiazine With potassium hydroxide In N,N-dimethyl-formamide at 20℃; Inert atmosphere;
Stage #2: 1 ,6-dibromohexane In N,N-dimethyl-formamide at 20℃; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;
55%
dimethylsulphoxide (DMSO)

dimethylsulphoxide (DMSO)

1-azaphenothiazine
261-96-1

1-azaphenothiazine

2-(3-bromopropyl)isoindole-1,3-dione
5460-29-7

2-(3-bromopropyl)isoindole-1,3-dione

3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propylamine
89929-26-0

3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propylamine

Conditions
ConditionsYield
With hydrazine hydrate In hydrogenchloride; ethanol; dimethyl sulfoxide8.3%
phosgene
75-44-5

phosgene

1-azaphenothiazine
261-96-1

1-azaphenothiazine

1-azaphenothiazine-10-carbonyl chloride
94231-78-4

1-azaphenothiazine-10-carbonyl chloride

Conditions
ConditionsYield
With hydrogenchloride; chlorobenzene at 170℃;
With hydrogenchloride In chlorobenzene at 170℃;
3-Chloropropionitrile
542-76-7

3-Chloropropionitrile

1-azaphenothiazine
261-96-1

1-azaphenothiazine

3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propionitrile
5622-88-8

3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propionitrile

Conditions
ConditionsYield
With sodium amide; xylene
1-azaphenothiazine
261-96-1

1-azaphenothiazine

acetic anhydride
108-24-7

acetic anhydride

10-acetyl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine
95873-97-5

10-acetyl-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

Conditions
ConditionsYield
With sodium acetate
1-azaphenothiazine
261-96-1

1-azaphenothiazine

dimethyl amine
124-40-3

dimethyl amine

1-Bromo-2-chloroethane
107-04-0

1-Bromo-2-chloroethane

(2-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-ethyl)-dimethyl-amine
67465-69-4

(2-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-ethyl)-dimethyl-amine

Conditions
ConditionsYield
With sodium amide; toluene aufeinanderfolgendes Erhitzen;
1-azaphenothiazine
261-96-1

1-azaphenothiazine

1-Bromo-2-chloroethane
107-04-0

1-Bromo-2-chloroethane

diethylamine
109-89-7

diethylamine

(2-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-ethyl)-diethyl-amine
67489-37-6

(2-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-ethyl)-diethyl-amine

Conditions
ConditionsYield
With sodium amide; toluene aufeinanderfolgendes Erhitzen;
1-azaphenothiazine
261-96-1

1-azaphenothiazine

2-(dimethylamino)ethyl chloride
107-99-3

2-(dimethylamino)ethyl chloride

(2-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-ethyl)-dimethyl-amine
67465-69-4

(2-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-ethyl)-dimethyl-amine

Conditions
ConditionsYield
With sodium amide; xylene
With sodium amide
1-azaphenothiazine
261-96-1

1-azaphenothiazine

3-(Dimethylamino)propyl chloride
109-54-6

3-(Dimethylamino)propyl chloride

prothipendyl
303-69-5

prothipendyl

Conditions
ConditionsYield
With sodium amide; xylene
With sodium amide

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