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Tianjin Kind Pharma Co., Ltd.

Factory direct sales, accept customization. Calcitriol (1,25-dihydroxylcholecaldiferol) is a steroid hormone with three hydroxyl groups, which is an active metabolite and the most effective form of vitamin D. Kind Pharma has its own laboratory, we

Calcitriol

Cas:32222-06-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Chemvon Biotechnology Co. Ltd.

Chemvon Biotechnology is one of the leading high-technology manufacturer in the field of pharmaceutical and fine chemical industry. From origins as a research group in technology service, chemvon has progressed into an integrated company with a k

Calcitriol

Cas:32222-06-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

good price,good quality,good service Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaos

Calcitriol

Cas:32222-06-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Luhan Pharmachem Co., Ltd

Luhan Pharmachem Co., Ltd. owns strong elite professional quality sales force, has the customer base from the US, Europe, Japan, Southeast Asia, Korea, Hong Kong, Taiwan and other countries and regions, the company operates in accordance with the mod

Calcitriol

Cas:32222-06-3

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Calcitriol Manufacturer/High quality/Best price/In stock

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hebei yanxi chemical co.,LTD.

Reason for Choosing us: 1): Superior Quality and Competitive Price: Our company is a renowned pharmaceutical manufacturer with more than 15 years experiences in China and all powders are supplying from our factory directly. 2): Fast ,Sa

Calcitriol CAS NO.32222-06-3

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Calcitriol Cas 32222-06-3 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white crystals Storage:Store at 2-8°C Package:1g/foill bag

Factory supply top quality Calcitriol Cas 32222-06-3 with best price and fast delivery

Cas:32222-06-3

Min.Order:1 Gram

FOB Price: $1100.0 / 1151.0

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

Paricalcitol CAS:131918-61-1 Doxercalciferol CAS:54573-75-0 Calcifediol CAS:63283-36-3 Alfacalcidol CAS:41294-56-8 Calcipotriol / Calcipotriene CAS:112828-00-9/112965-21-6 Calcipotriol Monohydrate CAS:147657-22-5 Bis-TBDMS-trans-calcipotri

High Purity Calcitriol 32222-06-3 In Bulk Supply

Cas:32222-06-3

Min.Order:1 Gram

Negotiable

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Calcitriol

Cas:32222-06-3

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Calcitriol 32222-06-3 ISO Producer

Cas:32222-06-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Calcitriol

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Calcitriol

Cas:32222-06-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

Calcitriol

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Calcitriol Basic information Physiological function Application Category Toxicity grading Acute toxicity Flammability and hazard characteristics Storage characteristics Extinguishing agent Product Name:

TIANFU-CHEM CAS:32222-06-3 Calcitriol

Cas:32222-06-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Calcitriol

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 32222-06-3 with competitive price

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat

Calcitriol

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $8888.0 / 9999.0

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details

China factory Supply High Quality CALCITRIOL CAS 32222-06-3 For Research Use only

Cas:32222-06-3

Min.Order:1 Gram

FOB Price: $5.0 / 10.0

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Item Name Calcitriol CAS NO 32222-06-3 Apparence White Powder Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:drum Application

Calcitriol

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 32222-06-3 Calcitriol with best price

Cas:32222-06-3

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Calcitriol 32222-06-3

Cas:32222-06-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High-quality Calcitriol manufacturer 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in China and ex

High-quality Calcitriol manufacturer

Cas:32222-06-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful d

cas 32222-06-3 Calcitriol Chinese manufacturer

Cas:32222-06-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Calcitriol

Cas:32222-06-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. 1. best service, high quality and reasonable way for h

98% Calcitriol;CAS:32222-06-3

Cas:32222-06-3

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Calcitriol

Cas:32222-06-3

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Calcitriol

Cas:32222-06-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white or yellowish white flaky crystal Storage:Keep the sun from direct sunlight ;prevention against high temperature Package:As customer request Application:Used for research and industrial manufacture. Transportatio

1A,25-dihydroxycholecalciferol

Cas:32222-06-3

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

1. "Top 100 innovation-oriented export enterprises Of Hangzhou" honored by Hangzhou government 2. Specialized in the fine chemicals and pharmaceuticals 3. A leading manufacturer and trader of APIs in China

Buy Calcitriol Hot sale Calcitriol price

Cas:32222-06-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Calcitriol

Cas:32222-06-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

[2H]-Pre-1,25-D3
57102-09-7

[2H]-Pre-1,25-D3

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
at 80℃;100%
In acetone at 80.3℃; for 3h;26 mg
at 70℃; for 2h;
In hexane; ethyl acetate at 65℃;182 mg
In acetone at 80.3℃; Rate constant; Equilibrium constant; Thermodynamic data; var. temp.; kinetics, E(a), ΔG(excit.), ΔH(excit.), ΔS(excit.);
C30H52O3Si

C30H52O3Si

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 0 - 20℃; for 10h; Inert atmosphere;100%
(1R,3aS,7aR)-1-((R)-5-Methoxymethoxy-1,5-dimethyl-hexyl)-7a-methyl-4-[2-[(3S,5R)-2-methylene-3,5-bis-triisopropylsilanyloxy-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-octahydro-indene
873567-12-5

(1R,3aS,7aR)-1-((R)-5-Methoxymethoxy-1,5-dimethyl-hexyl)-7a-methyl-4-[2-[(3S,5R)-2-methylene-3,5-bis-triisopropylsilanyloxy-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-octahydro-indene

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 2h;95%
C45H86O3Si3

C45H86O3Si3

A

2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3

2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3

B

1α,25-dihydroxy-2-methylene-19-nor-vitamin D3

1α,25-dihydroxy-2-methylene-19-nor-vitamin D3

C

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With AG 50W-X4 resin In methanol; benzene at 20℃; for 19h;A 95%
B n/a
C n/a
C51H98O3Si3

C51H98O3Si3

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 24h;81%
1α-[(triethylsilyl)oxy]-24-(tert-butoxycarbonyl)-25,26,27-trisnorvitamin D3 triethylsilyl ether

1α-[(triethylsilyl)oxy]-24-(tert-butoxycarbonyl)-25,26,27-trisnorvitamin D3 triethylsilyl ether

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
Stage #1: 1α-[(triethylsilyl)oxy]-24-(tert-butoxycarbonyl)-25,26,27-trisnorvitamin D3 triethylsilyl ether With methyllithium In diethyl ether at 0℃; for 0.5h;
Stage #2: With tetrabutyl ammonium fluoride In tetrahydrofuran for 0.75h; Darkness;
81%
methyllithium
917-54-4

methyllithium

1α-Hydroxy-25-oxo-27-norvitamin D3
77531-53-4

1α-Hydroxy-25-oxo-27-norvitamin D3

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
In diethyl ether at -78℃; for 0.333333h;80%
(1S),3(R)-9,10-secocholesta-5(E),7(E),10(19)-triene-1,3,25-triol
73837-24-8

(1S),3(R)-9,10-secocholesta-5(E),7(E),10(19)-triene-1,3,25-triol

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With 9-acetylanthracene In ethanol Inert atmosphere; UV-irradiation; Cooling with ice;78%
With 9-acetylanthracene In methanol at 0℃; for 2h; Irradiation;66%
(1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol
140710-96-9

(1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With n-BuNF In tetrahydrofuran at 45℃; for 4h;71%
With tetrabutyl ammonium fluoride In tetrahydrofuran for 24h; Ambient temperature; in the dark; Yield given;
With camphor-10-sulfonic acid In methanol at 20℃; for 12h; desilylation;
(1R,3R)-5-{(Z)-2-[(1R,3aR,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl]-vinyl}-4-methyl-cyclohex-4-ene-1,3-diol

(1R,3R)-5-{(Z)-2-[(1R,3aR,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl]-vinyl}-4-methyl-cyclohex-4-ene-1,3-diol

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
In acetone at 80℃; for 4h;70%
7,8-cis-1α,25-dihydroxyvitamin D3
157809-60-4

7,8-cis-1α,25-dihydroxyvitamin D3

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With 9-acetylanthracene In d(4)-methanol for 1.5h; Irradiation;67%
(1R,3aR,7aR)-4-{(E)-2-[(1S,3S,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-bicyclo[3.1.0]hex-1-yl]-vinyl}-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ol
135446-94-5

(1R,3aR,7aR)-4-{(E)-2-[(1S,3S,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-bicyclo[3.1.0]hex-1-yl]-vinyl}-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ol

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With toluene-4-sulfonic acid In 1,4-dioxane; water64%
(R)-1-[(1S,3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexyl]-2-[(1R,3aS,7aR)-1-[(R)-5-(tert-butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-7a-methyl-octahydro-inden-(4E)-ylidene]-ethanol
130759-99-8

(R)-1-[(1S,3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexyl]-2-[(1R,3aS,7aR)-1-[(R)-5-(tert-butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-7a-methyl-octahydro-inden-(4E)-ylidene]-ethanol

A

calcitriol
32222-06-3

calcitriol

B

(1R,3S,5R)-5-{(E)-2-[(1R,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-inden-4-yl]-vinyl}-4-methylene-cyclohexane-1,3-diol
130760-01-9

(1R,3S,5R)-5-{(E)-2-[(1R,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-inden-4-yl]-vinyl}-4-methylene-cyclohexane-1,3-diol

Conditions
ConditionsYield
With hydrogen fluoride; silica gel; copper(II) sulfate 1) C6H6, 50 deg C, 1.5h, 2) MeOH, THF, r.t., 5h; Yield given. Multistep reaction;A n/a
B 57%
With hydrogen fluoride; silica gel; copper(II) sulfate 1) C6H6, 50 deg C, 1.5h, 2) MeOH, THF, r.t., 5h; Yield given. Multistep reaction;A 33%
B n/a
(1S,6R)-1-hydroxy-6-(1,3-benzodithiol-2-yloxy)-25-tetrahydropyranyloxy-3,5-cyclovitamin D3
161003-71-0

(1S,6R)-1-hydroxy-6-(1,3-benzodithiol-2-yloxy)-25-tetrahydropyranyloxy-3,5-cyclovitamin D3

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With phosphomolybdic acid hydrate In 1,4-dioxane; water at 30℃; for 3h;30%
1α,3β,25-trihydroxycholesta-5,7-diene
61954-91-4

1α,3β,25-trihydroxycholesta-5,7-diene

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
Stage #1: 1α,3β,25-trihydroxycholesta-5,7-diene In 1,4-dioxane High-pressure mercury lamp;
Stage #2: at 100℃; Photomicroreactor; thermalmicroreactor;
8%
(i) EtOH, (UV-irradiation), (ii) (heating); Multistep reaction;
Multi-step reaction with 2 steps
1: tBuOMe / 0.92 h / -45 °C / Irradiation
2: 182 mg / ethyl acetate; hexane / 65 °C
View Scheme
Multi-step reaction with 3 steps
1: 6 mg / tBuOMe / 0.92 h / -45 °C / Irradiation
2: 25 mg / tBuOMe, fluorenone / -5 °C / Irradiation
3: 182 mg / ethyl acetate; hexane / 65 °C
View Scheme
(1R,3aR,7aR)-1-{(1R)-1,5-dimethyl-5-[(trimethylsilyl)oxy]hexyl}-7a-methyloctahydro-4H-inden-4-one
81506-41-4

(1R,3aR,7aR)-1-{(1R)-1,5-dimethyl-5-[(trimethylsilyl)oxy]hexyl}-7a-methyloctahydro-4H-inden-4-one

[(2Z)-2-[(3S,5R)-3,5-bis(tert-butyldimethylsilanyloxy)-2-methylenecyclohexylidene]ethyl]diphenylphosphine oxide
81522-68-1

[(2Z)-2-[(3S,5R)-3,5-bis(tert-butyldimethylsilanyloxy)-2-methylenecyclohexylidene]ethyl]diphenylphosphine oxide

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With n-butyllithium 1.) THF, n-hexane, -78 deg C, 5 min, 2.) THF, n-hexane, -78 deg C, 2 h; Yield given. Multistep reaction;
<1R-<1α(R*),3aβ,4α<(E)-(1S*,3S*,5R*)>,7aα>>-octahydro-4-hydroxy-4-<2-(3-hydroxy-2-methylenebicyclo<3.1.0>hexan-1-yl)ethenyl>-α,α,ε-tetramethyl-1H-indene-pentanol
135041-06-4

<1R-<1α(R*),3aβ,4α<(E)-(1S*,3S*,5R*)>,7aα>>-octahydro-4-hydroxy-4-<2-(3-hydroxy-2-methylenebicyclo<3.1.0>hexan-1-yl)ethenyl>-α,α,ε-tetramethyl-1H-indene-pentanol

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With toluene-4-sulfonic acid 1.) dioxan, water; 2.) t-butylmethyl ether, irradiation; Yield given. Multistep reaction;
With tert-butyl methyl ether; 9-acetoxyanthracene; toluene-4-sulfonic acid 1.) dioxane, H2O, 75 deg C, 4 h, 2.) irradiation, 1 h; Yield given. Multistep reaction;
anti-3-(tertbutyldimethylsiloxy)-5-(tert-butyldiphenylsiloxy)-1-octen-7-yne
138924-21-7

anti-3-(tertbutyldimethylsiloxy)-5-(tert-butyldiphenylsiloxy)-1-octen-7-yne

(E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol
143705-63-9

(E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tetrabutyl ammonium fluoride; thiamine diphosphate; triethylamine 1.) toluene, reflux, 2 h, 2.) THF, RT, 30 h; Yield given. Multistep reaction;
(3bR,5aR,6R,8aR,10S)-10-((3S,5R)-3,5-Dihydroxy-2-methyl-cyclohex-1-enyl)-6-((R)-5-hydroxy-1,5-dimethyl-hexyl)-5a-methyl-2-phenyl-4,5,5a,6,7,8,8a,10-octahydro-3bH-2,3a,10a-triaza-dicyclopenta[a,f]naphthalene-1,3-dione
86307-44-0

(3bR,5aR,6R,8aR,10S)-10-((3S,5R)-3,5-Dihydroxy-2-methyl-cyclohex-1-enyl)-6-((R)-5-hydroxy-1,5-dimethyl-hexyl)-5a-methyl-2-phenyl-4,5,5a,6,7,8,8a,10-octahydro-3bH-2,3a,10a-triaza-dicyclopenta[a,f]naphthalene-1,3-dione

A

calcitriol
32222-06-3

calcitriol

B

[2H]-Pre-1,25-D3
57102-09-7

[2H]-Pre-1,25-D3

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 85℃; for 70h;A 51 mg
B 9 mg
(3-bromo-1,1-dimethylpropoxy)triethylsilane
87417-12-7

(3-bromo-1,1-dimethylpropoxy)triethylsilane

1α,3β-bis<(triethylsilyl)oxy>-20(S)-<<(p-tolylsulfonyl)oxy>methyl>-9,10-secopregna-5(Z),7(E),10(19)-triene
87417-31-0

1α,3β-bis<(triethylsilyl)oxy>-20(S)-<<(p-tolylsulfonyl)oxy>methyl>-9,10-secopregna-5(Z),7(E),10(19)-triene

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With copper(l) iodide; tetrabutyl ammonium fluoride; magnesium Yield given. Multistep reaction;
3β-tert-butyldimethylsilyl-1α-tert-butyldimethylsilyloxy-25-trimethylsilyloxy-19-norvitamin D3
599165-21-6

3β-tert-butyldimethylsilyl-1α-tert-butyldimethylsilyloxy-25-trimethylsilyloxy-19-norvitamin D3

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 25℃; Yield given;
With tetrabutyl ammonium fluoride In tetrahydrofuran
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 24h;68.3 mg
1-Oxo-25-hydroxyprevitamin D3
66760-28-9

1-Oxo-25-hydroxyprevitamin D3

A

calcitriol
32222-06-3

calcitriol

B

[2H]-Pre-1,25-D3
57102-09-7

[2H]-Pre-1,25-D3

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid In tetrahydrofuran for 2h; Ambient temperature;A 2.4 mg
B 11.4 mg
((5Z,7E,1S,3R)-1,25-Dihydroxy-9,10-seco-5,7,10(19)-cholestatrien-3-yl)-β-D-glucopyranosid

((5Z,7E,1S,3R)-1,25-Dihydroxy-9,10-seco-5,7,10(19)-cholestatrien-3-yl)-β-D-glucopyranosid

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With β-glucosidase In water for 24h; Ambient temperature; formation of aglycone;
2-{(1S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[2-[(1R,3aS,7aR)-1-((R)-1,5-dimethyl-5-trimethylsilanyloxy-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-2-methylene-cyclohexyloxy}-tetrahydro-pyran

2-{(1S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[2-[(1R,3aS,7aR)-1-((R)-1,5-dimethyl-5-trimethylsilanyloxy-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-2-methylene-cyclohexyloxy}-tetrahydro-pyran

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
With camphor-10-sulfonic acid In methanol; water at 30℃; for 6h;
vitamin D3
67-97-0

vitamin D3

A

2alpha,25-Dihydroxyvitamin D3

2alpha,25-Dihydroxyvitamin D3

B

calcitriol
32222-06-3

calcitriol

C

calcidiol
19356-17-3

calcidiol

Conditions
ConditionsYield
With Pseudonocardia autotrophica 100U-19 cells In ethanol at 30℃; for 72h;A 35 mg
B n/a
C n/a
de-A,B-25-[(methoxymethyl)oxy]-cholestan-8-one
873567-08-9

de-A,B-25-[(methoxymethyl)oxy]-cholestan-8-one

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: t-BuLi / diethyl ether; pentane / 0.5 h / -78 °C
1.2: ZnBr2 / tetrahydrofuran; diethyl ether; pentane / -78 - -10 °C
1.3: 75 percent / Et3N / (Ph3P)4Pd / tetrahydrofuran; diethyl ether; pentane / -40 - 20 °C
2.1: 95 percent / n-Bu4NF / tetrahydrofuran / 2 h / 20 °C
View Scheme
Grundmann's alcohol
33813-99-9

Grundmann's alcohol

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 95 percent / (trifluoromethyl)methyldioxirane / CH2Cl2 / 2 h / -20 °C
2.1: 96 percent / i-Pr2NEt; DMAP / CH2Cl2 / 24 h / 20 °C
3.1: HMDS / tetrahydrofuran / 2 h / -60 °C
3.2: 60 percent / tetrahydrofuran / 17 h / -60 - -5 °C
4.1: t-BuLi / diethyl ether; pentane / 0.5 h / -78 °C
4.2: ZnBr2 / tetrahydrofuran; diethyl ether; pentane / -78 - -10 °C
4.3: 75 percent / Et3N / (Ph3P)4Pd / tetrahydrofuran; diethyl ether; pentane / -40 - 20 °C
5.1: 95 percent / n-Bu4NF / tetrahydrofuran / 2 h / 20 °C
View Scheme
(1R,3aR,7aR)-1-[(2R)-6-hydroxy-6-methylhept-2-yl]-7a-methyloctahydroinden-4-one
70550-73-1

(1R,3aR,7aR)-1-[(2R)-6-hydroxy-6-methylhept-2-yl]-7a-methyloctahydroinden-4-one

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 96 percent / i-Pr2NEt; DMAP / CH2Cl2 / 24 h / 20 °C
2.1: HMDS / tetrahydrofuran / 2 h / -60 °C
2.2: 60 percent / tetrahydrofuran / 17 h / -60 - -5 °C
3.1: t-BuLi / diethyl ether; pentane / 0.5 h / -78 °C
3.2: ZnBr2 / tetrahydrofuran; diethyl ether; pentane / -78 - -10 °C
3.3: 75 percent / Et3N / (Ph3P)4Pd / tetrahydrofuran; diethyl ether; pentane / -40 - 20 °C
4.1: 95 percent / n-Bu4NF / tetrahydrofuran / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 1.) sodium hexamethyldisilazide / 1.) THF, -60 deg C, 1 h, 2.) THF, RT, 30 min
2: 1.) (dba)3Pd2*CHCl3, TPP, Et3N, 2.) TBAF / 1.) toluene, reflux, 2 h, 2.) THF, RT, 30 h
View Scheme
Multi-step reaction with 2 steps
1: 98 percent / CH2Cl2 / 18 h / Ambient temperature
2: 1.) n-BuLi / 1.) THF, n-hexane, -78 deg C, 5 min, 2.) THF, n-hexane, -78 deg C, 2 h
View Scheme
Multi-step reaction with 3 steps
1: 98 percent / tetrahydrofuran / 25 °C
2: tetrahydrofuran / 1 h / -78 °C
3: (Bu)4NF / tetrahydrofuran / 25 °C
View Scheme
(1R,6R,7R)-7-[(R)-6-(methoxymethoxy)-6-methylheptan-2-yl]-6-methylbicyclo[4.3.0]nonan-2-one
139619-80-0

(1R,6R,7R)-7-[(R)-6-(methoxymethoxy)-6-methylheptan-2-yl]-6-methylbicyclo[4.3.0]nonan-2-one

calcitriol
32222-06-3

calcitriol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: HMDS / tetrahydrofuran / 2 h / -60 °C
1.2: 60 percent / tetrahydrofuran / 17 h / -60 - -5 °C
2.1: t-BuLi / diethyl ether; pentane / 0.5 h / -78 °C
2.2: ZnBr2 / tetrahydrofuran; diethyl ether; pentane / -78 - -10 °C
2.3: 75 percent / Et3N / (Ph3P)4Pd / tetrahydrofuran; diethyl ether; pentane / -40 - 20 °C
3.1: 95 percent / n-Bu4NF / tetrahydrofuran / 2 h / 20 °C
View Scheme
calcitriol
32222-06-3

calcitriol

4-<2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl>-1,2,4-triazoline-3,5-dione
132788-52-4

4-<2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl>-1,2,4-triazoline-3,5-dione

C42H59N5O8
132788-59-1

C42H59N5O8

Conditions
ConditionsYield
In dichloromethane Ambient temperature;100%
calcitriol
32222-06-3

calcitriol

6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid 4-(3,5-dioxo-3,5-dihydro-[1,2,4]triazol-4-yl)-benzyl ester
132788-51-3

6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxaline-2-carboxylic acid 4-(3,5-dioxo-3,5-dihydro-[1,2,4]triazol-4-yl)-benzyl ester

C48H61N5O10
132788-58-0

C48H61N5O10

Conditions
ConditionsYield
Ambient temperature;100%
calcitriol
32222-06-3

calcitriol

1-Oxo-25-hydroxyprevitamin D3
66760-28-9

1-Oxo-25-hydroxyprevitamin D3

Conditions
ConditionsYield
With Dess-Martin periodane In acetonitrile for 2h; Ambient temperature;88%
calcitriol
32222-06-3

calcitriol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol
140710-96-9

(1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 1h;80%
calcitriol
32222-06-3

calcitriol

N-(benzo-15-crown-5)-1,2,4-triazole-3,5-dione

N-(benzo-15-crown-5)-1,2,4-triazole-3,5-dione

C43H63N3O10

C43H63N3O10

Conditions
ConditionsYield
In ethyl acetate at 25℃;45%
calcitriol
32222-06-3

calcitriol

[2H]-Pre-1,25-D3
57102-09-7

[2H]-Pre-1,25-D3

Conditions
ConditionsYield
In acetone at 80.3℃; Equilibrium constant; var. temp.;
In benzene-d6 at 80℃; Rate constant;
Multi-step reaction with 2 steps
1: 88 percent / Dess-Martin reagent / acetonitrile / 2 h / Ambient temperature
2: 11.4 mg / sodium triacetoxyborohydride, AcOH / tetrahydrofuran / 2 h / Ambient temperature
View Scheme
calcitriol
32222-06-3

calcitriol

(4S,6R)-1-[(1R,3aS,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ6-benzo[c]thiophene-4,6-diol
140710-95-8

(4S,6R)-1-[(1R,3aS,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ6-benzo[c]thiophene-4,6-diol

Conditions
ConditionsYield
With sulfur dioxide for 1h; Heating;
With sulfur dioxide In dichloromethane at -15℃; for 3h; Yield given;
calcitriol
32222-06-3

calcitriol

1α,25-dihydroxy-6,19-dihydro-6,19-epidioxyvitamin D3

1α,25-dihydroxy-6,19-dihydro-6,19-epidioxyvitamin D3

Conditions
ConditionsYield
With oxygen; rose bengal In ethanol for 1.5h; Irradiation; Yield given;

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