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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-(Trifluoromethyl)benzyl bromide Manufacturer/High quality/Best price/In stock

Cas:395-44-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-(Trifluoromethyl)Benzyl Bromide

Cas:395-44-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2-(TrifluoroMethyl)benzyl BroMide

Cas:395-44-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-(Trifluoromethyl)Benzyl Bromide

Cas:395-44-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-(Trifluoromethyl)-benzyl bromide

Cas:395-44-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 2-(Trifluoromethyl)benzyl bromide CAS No. 395-44-8

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:1 Metric Ton

FOB Price: $12.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

1-(Bromomethyl)-2-(trifluoromethyl)benzene CAS 395-44-8

Cas:395-44-8

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

2-(Trifluoromethyl)benzyl bromide 395-44-8

Cas:395-44-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 395-44-8 with fast shipping

Cas:395-44-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Liquid Storage:Store in sealed containers at cool & dry plac

CAS 395-44-8 | 2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzene,1-(bromomethyl)-2-(trifluoromethyl)- 395-44-8

Cas:395-44-8

Min.Order:1 Kilogram

Negotiable

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Qingdao Beluga Import and Export Co., LTD

2-(Trifluoromethyl)benzyl bromide CAS:395-44-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality o

2-(Trifluoromethyl)benzyl bromide CAS:395-44-8

Cas:395-44-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-(Trifluoromethyl)Benzyl Bromide

Cas:395-44-8

Min.Order:0

Negotiable

Type:Manufacturers

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

1-(Bromomethyl)-2-(trifluoromethyl)benzene

Cas:395-44-8

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzene,1-(bromomethyl)-2-(trifluoromethyl)-

Cas:395-44-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-(bromomethyl)-2-(trifluoromethyl)benzene

Cas:395-44-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 1-(bromomethyl)-2-(trifluoromethyl)benzene

Cas:395-44-8

Min.Order:0

Negotiable

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

2-(Trifluoromethyl)benzyl bromide 395-44-8CAS NO.: 395-44-8

Cas:395-44-8

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

2-(Trifluoromethyl)benzyl bromide Chemical Properties Melting point 34-35 °C Boiling point 72 °C (7.5 mmHg) density 1.571 g/mL at 25 °C(lit.) refractive index 1.496-1.499 Fp 83 °C Specific Gravity 1.571 Sensitiv

2-(Trifluoromethyl)benzyl Bromide

Cas:395-44-8

Min.Order:1 Kilogram

FOB Price: $65.0

Type:Lab/Research institutions

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-Trifluoromethylbenzyl bromide

Cas:395-44-8

Min.Order:0

Negotiable

Type:Manufacturers

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:1 Kilogram

Negotiable

Type:Other

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Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

2-(Trifluoromethyl)benzyl bromide

Cas:395-44-8

Min.Order:0

Negotiable

Type:Manufacturers

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-trifluoromethylbenzylbromide

Cas:395-44-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-(Trifluoromethyl)Benzyl bromide cas no. 395-44-8 98%

Cas:395-44-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

diethyl 2,6-dimethyl-4-(2-(trifluoromethyl)benzyl)-1,4-dihydropyridine-3,5-dicarboxylate

diethyl 2,6-dimethyl-4-(2-(trifluoromethyl)benzyl)-1,4-dihydropyridine-3,5-dicarboxylate

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

Conditions
ConditionsYield
With dipotassium peroxodisulfate; tris(2,2′-bipyridyl)dichlororuthenium(II) hexahydrate; sodium bromide In water; acetonitrile at 20℃; for 24h; Sealed tube; Inert atmosphere; Irradiation; regioselective reaction;62%
(2-(trifluoromethyl)phenyl)methanol
346-06-5

(2-(trifluoromethyl)phenyl)methanol

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

Conditions
ConditionsYield
(bromination);
With pyridine; phosphorus tribromide at -10 - -5℃;
With sulfuric acid; hydrogen bromide
With carbon tetrabromide; triphenylphosphine In dichloromethane for 2h; Substitution; reflux;
With phosphorus tribromide In dichloromethane; water; toluene
[2-(trifluoromethyl)phenyl]magnesium bromide
395-47-1

[2-(trifluoromethyl)phenyl]magnesium bromide

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: (bromination)
View Scheme
2-trifluoromethylbenzoic acid
433-97-6

2-trifluoromethylbenzoic acid

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: LiAlH4 / diethyl ether
2: PBr3, Py / -10 - -5 °C
View Scheme
2-trifluoromethylphenylmagnesium chloride
3796-19-8

2-trifluoromethylphenylmagnesium chloride

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: aq. HBr, H2SO4
View Scheme
2-Trifluoromethylbenzaldehyde
447-61-0

2-Trifluoromethylbenzaldehyde

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetra(n-butyl)ammonium hydrogensulfate / ethylene glycol / 4 h / 80 °C / Sealed tube; Inert atmosphere
2: sodium bromide; dipotassium peroxodisulfate; tris(2,2′-bipyridyl)dichlororuthenium(II) hexahydrate / acetonitrile; water / 24 h / 20 °C / Sealed tube; Inert atmosphere; Irradiation
View Scheme
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

triphenylphosphine
603-35-0

triphenylphosphine

2-trifluoromethylbenzyltriphenylphosphonium bromide

2-trifluoromethylbenzyltriphenylphosphonium bromide

Conditions
ConditionsYield
In toluene for 12h; Reflux;100%
In toluene Reflux;77%
In toluene at 80℃; for 16h;
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

A

6-((2-(trifluoromethyl)benzyl)thio)-9H-purine

6-((2-(trifluoromethyl)benzyl)thio)-9H-purine

B

9-[2-(trifluoromethyl) benzyl]-6-[(2-(trifluoromethyl)benzyl)thio]-9H-purine

9-[2-(trifluoromethyl) benzyl]-6-[(2-(trifluoromethyl)benzyl)thio]-9H-purine

Conditions
ConditionsYield
Stage #1: 6-Mercaptopurine With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 20℃; Further stages;
A 91%
B 99%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

Quinoline-2-thiol
2637-37-8

Quinoline-2-thiol

2-((2-(trifluoromethyl)benzyl)thio)quinoline

2-((2-(trifluoromethyl)benzyl)thio)quinoline

Conditions
ConditionsYield
Stage #1: Quinoline-2-thiol With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 20℃; for 0.5h;
Stage #2: o-trifluoromethylbenzyl bromide In toluene at 20℃; for 17h;
99%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

m-nitrobenzene boronic acid
13331-27-6

m-nitrobenzene boronic acid

1-(3-nitrobenzyl)-2-(trifluoromethyl)benzene
886211-35-4

1-(3-nitrobenzyl)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,2-dimethoxyethane; water at 50℃; for 16h;98%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

5-bromosalicyclaldehyde
1761-61-1

5-bromosalicyclaldehyde

5-bromo-2-[2-(trifluoromethyl)benzyloxy]benzaldehyde
1198307-34-4

5-bromo-2-[2-(trifluoromethyl)benzyloxy]benzaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;98%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

phenylboronic acid
98-80-6

phenylboronic acid

1-benzyl-2-(trifluoromethyl)benzene
7552-71-8

1-benzyl-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With trans-(imidazole-κN)diiodo(3-isopropylbenzothiazolin-2-ylidene)palladium(II); potassium carbonate In water; N,N-dimethyl-formamide at 60℃; for 2h; Suzuki-Miyaura coupling;98%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl 2-cyano-3-[2-(trifluoromethyl)phenyl]-2-{[2-(trifluoromethyl)phenyl]methyl}propionate

methyl 2-cyano-3-[2-(trifluoromethyl)phenyl]-2-{[2-(trifluoromethyl)phenyl]methyl}propionate

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 0℃; for 0.0333333h;
Stage #2: o-trifluoromethylbenzyl bromide In dichloromethane at 0 - 20℃;
98%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃;
ethyl 6-(4-fluorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-4-pyridazinecarboxylate
1040543-17-6

ethyl 6-(4-fluorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-4-pyridazinecarboxylate

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

ethyl 6-(4-fluorophenyl)-5-hydroxy-3-oxo-2-{[2-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-4-pyridazinecarboxylate
1040544-19-1

ethyl 6-(4-fluorophenyl)-5-hydroxy-3-oxo-2-{[2-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-4-pyridazinecarboxylate

Conditions
ConditionsYield
Stage #1: ethyl 6-(4-fluorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-4-pyridazinecarboxylate With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.75h;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 0 - 20℃; for 3h;
Stage #3: With hydrogenchloride In water; N,N-dimethyl-formamide at 20℃;
97%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

4-methoxy-2-nitroaniline
96-96-8

4-methoxy-2-nitroaniline

4-methoxy-2-nitro-N-(2-(trifluoromethyl)benzyl)aniline

4-methoxy-2-nitro-N-(2-(trifluoromethyl)benzyl)aniline

Conditions
ConditionsYield
Stage #1: 4-methoxy-2-nitroaniline With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 0.5h; Inert atmosphere;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 90℃; Inert atmosphere;
97%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine
103057-44-9

N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine

(±)-tert-butyl 3-((2-(trifluoromethyl)benzyl)oxy)pyrrolidine-1-carboxylate

(±)-tert-butyl 3-((2-(trifluoromethyl)benzyl)oxy)pyrrolidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Inert atmosphere;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 0 - 25℃; for 16h; Inert atmosphere;
97%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

N-(diphenylmethylene)glycine tert-butyl ester
81477-94-3

N-(diphenylmethylene)glycine tert-butyl ester

(S)-tert-butyl 3-(2-trifluoromethylphenyl)-2-(diphenylmethyleneamino)propanoate

(S)-tert-butyl 3-(2-trifluoromethylphenyl)-2-(diphenylmethyleneamino)propanoate

Conditions
ConditionsYield
With C58H42F12N(1+)*Br(1-); potassium hydroxide In water; toluene at -20℃; for 3h; Reagent/catalyst; enantioselective reaction;96%
With C30H32N3O(1+)*Br(1-); potassium hydroxide In water; toluene at -40℃; for 10h; Reagent/catalyst; enantioselective reaction;95%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

trimethylphosphane
594-09-2

trimethylphosphane

trimethyl(2-(trifluoromethyl)benzyl)phosphonium bromide

trimethyl(2-(trifluoromethyl)benzyl)phosphonium bromide

Conditions
ConditionsYield
In toluene; acetonitrile at 20℃; for 1h; Inert atmosphere;96%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

C45H45F3N2O6

C45H45F3N2O6

Conditions
ConditionsYield
With triethylhexadecylammonium chloride In water at 200℃; for 0.1h; Reagent/catalyst; Solvent; Temperature;95.81%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

1-(azidomethyl)-2-(trifluoromethyl)benzene
823189-03-3

1-(azidomethyl)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With sodium azide In water; tert-butyl alcohol95.8%
With sodium azide In water; acetone90%
With sodium azide In water; acetone at 22℃;87%
3,4-dihydro-2(1H)-quinolone
553-03-7

3,4-dihydro-2(1H)-quinolone

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

1-[2-(trifluoromethyl)benzyl]-3,4-dihydroquinolin-2(1H)-one
1247021-75-5

1-[2-(trifluoromethyl)benzyl]-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 3,4-dihydro-2(1H)-quinolone With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 20℃;
95%
(3α,5α)-3-hydroxy-3-(piperazin-1-ylmethyl)androstan-17-one
1326702-42-4

(3α,5α)-3-hydroxy-3-(piperazin-1-ylmethyl)androstan-17-one

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

(3α,5α)-3-hydroxy-3-((4-[2-(trifluoromethyl)benzyl]-piperazin-1-yl)methyl)androstan-17-one
1326702-55-9

(3α,5α)-3-hydroxy-3-((4-[2-(trifluoromethyl)benzyl]-piperazin-1-yl)methyl)androstan-17-one

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃;95%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isoselenuronium bromide
50793-60-7

2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isoselenuronium bromide

2-(trifluoromethyl)benzyl 2,3,4,6-tetra-O-acetyl-1-seleno-β-D-glucopyranoside
1383478-50-9

2-(trifluoromethyl)benzyl 2,3,4,6-tetra-O-acetyl-1-seleno-β-D-glucopyranoside

Conditions
ConditionsYield
With triethylamine at 20℃;95%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

C18H21NO
115-46-8

C18H21NO

(1-(2-(trifluoromethyl)benzyl)piperidin-4-yl)diphenylmethanol

(1-(2-(trifluoromethyl)benzyl)piperidin-4-yl)diphenylmethanol

Conditions
ConditionsYield
With triethylamine In acetonitrile at 70℃; for 4h;95%
Na[CpMo(CO)3]
12107-35-6

Na[CpMo(CO)3]

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

[CpMo(CO)3Bz-o-CF3]

[CpMo(CO)3Bz-o-CF3]

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 24h;95%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

mercaptoacetic acid
68-11-1

mercaptoacetic acid

2-[2-(trifluoromethyl)benzylthio]acetic acid

2-[2-(trifluoromethyl)benzylthio]acetic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; for 1h;94.5%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

1-(4-methylbenzyl)-2-(trifluoromethyl)benzene
1130704-36-7

1-(4-methylbenzyl)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With trans-(benzimidazole-κN)diiodo(3-isopropylbenzothiazolin-2-ylidene)palladium(II); potassium carbonate In water; N,N-dimethyl-formamide at 60℃; for 17h; Suzuki-Miyaura coupling;94%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

N-t-butoxycarbonyl-tyramine
64318-28-1

N-t-butoxycarbonyl-tyramine

tert-butyl (4-((2-(trifluoromethyl)benzyl)oxy)phenethyl)carbamate

tert-butyl (4-((2-(trifluoromethyl)benzyl)oxy)phenethyl)carbamate

Conditions
ConditionsYield
With potassium carbonate In acetone for 4h; Williamson Ether Synthesis; Reflux;94%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

N-(diphenylmethylene)glycine tert-butyl ester
81477-94-3

N-(diphenylmethylene)glycine tert-butyl ester

(R)-tert-butyl 3-(2-trifluoromethylphenyl)-2-(diphenylmethyleneamino)propanoate

(R)-tert-butyl 3-(2-trifluoromethylphenyl)-2-(diphenylmethyleneamino)propanoate

Conditions
ConditionsYield
With C28H28F6N3(1+)*Br(1-); potassium hydroxide In diethyl ether; water at -40℃; for 5h; enantioselective reaction;93%
4-tert-Butylstyrene
1746-23-2

4-tert-Butylstyrene

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

butan-1-ol
71-36-3

butan-1-ol

1-(3-butoxy-3-(4-tert-butylphenyl)propyl)-2-(trifluoromethyl)benzene

1-(3-butoxy-3-(4-tert-butylphenyl)propyl)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With sodium carbonate; copper(l) chloride at 100℃; for 24h; Inert atmosphere; Schlenk technique;93%
2-(4-chlorophenoxy)-1,3-propanedioic acid diethyl ester
24101-91-5

2-(4-chlorophenoxy)-1,3-propanedioic acid diethyl ester

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

diethyl 2-(4-chlorophenoxy)-2-[2-(trifluormethyl)benzyl]malonate
1093231-91-4

diethyl 2-(4-chlorophenoxy)-2-[2-(trifluormethyl)benzyl]malonate

Conditions
ConditionsYield
Stage #1: 2-(4-chlorophenoxy)-1,3-propanedioic acid diethyl ester With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.333333h;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 20 - 60℃;
92%
1,1-dimethylethyl (3S)-3-[(3-chloro-4-cyanophenyl)amino]-1-pyrrolidnecarboxylate
940865-64-5

1,1-dimethylethyl (3S)-3-[(3-chloro-4-cyanophenyl)amino]-1-pyrrolidnecarboxylate

o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

1,1-dimethylethyl (3S)-3-((3-chloro-4-cyanophenyl){[2-(trifluoromethyl)phenyl]methyl}amino)-1-pyrrolidinecarboxylate
940865-65-6

1,1-dimethylethyl (3S)-3-((3-chloro-4-cyanophenyl){[2-(trifluoromethyl)phenyl]methyl}amino)-1-pyrrolidinecarboxylate

Conditions
ConditionsYield
Stage #1: 1,1-dimethylethyl (3S)-3-[(3-chloro-4-cyanophenyl)amino]-1-pyrrolidnecarboxylate With sodium hydride In N,N-dimethyl-formamide for 1h; Cooling with ice;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 0 - 25℃; for 1h;
92%
Stage #1: 1,1-dimethylethyl (3S)-3-[(3-chloro-4-cyanophenyl)amino]-1-pyrrolidnecarboxylate With sodium hydride In hexane; N,N-dimethyl-formamide at 0℃; for 1h;
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;
Stage #3: With water; ammonium chloride In N,N-dimethyl-formamide
92%
Stage #1: 1,1-dimethylethyl (3S)-3-[(3-chloro-4-cyanophenyl)amino]-1-pyrrolidnecarboxylate With sodium hydride In N,N-dimethyl-formamide; mineral oil
Stage #2: o-trifluoromethylbenzyl bromide In N,N-dimethyl-formamide; mineral oil
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

(S)-1-(2,6-diisopropylphenyl)-4-isopropyl-4,5-dihydro-1H-imidazole

(S)-1-(2,6-diisopropylphenyl)-4-isopropyl-4,5-dihydro-1H-imidazole

(S)-1-(2,6-diisopropylphenyl)-4-isopropyl-3-(2-(trifluoromethyl)benzyl)-4,5-dihydro-1Himidazol-3-ium bromide

(S)-1-(2,6-diisopropylphenyl)-4-isopropyl-3-(2-(trifluoromethyl)benzyl)-4,5-dihydro-1Himidazol-3-ium bromide

Conditions
ConditionsYield
In toluene at 100℃; for 1h;92%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

(3aS,9bR)-8-hydroxy-6,9-dimethyl-3-methylene-3a,4,5,9b-tetrahydronaphtho[1,2-b]furan-2(3H)-one

(3aS,9bR)-8-hydroxy-6,9-dimethyl-3-methylene-3a,4,5,9b-tetrahydronaphtho[1,2-b]furan-2(3H)-one

(3aS,9bR)-6,9-dimethyl-3-methylene-8-((2-(trifluoromethyl)-benzyl)oxy)-3a,4,5,9b-tetrahydronaphtho[1,2-b]furan-2(3H)-one

(3aS,9bR)-6,9-dimethyl-3-methylene-8-((2-(trifluoromethyl)-benzyl)oxy)-3a,4,5,9b-tetrahydronaphtho[1,2-b]furan-2(3H)-one

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃;92%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

ethyl 1-(2-fluoropyridin-4-yl)-4-hydroxy-1H-pyrazole-3-carboxylate

ethyl 1-(2-fluoropyridin-4-yl)-4-hydroxy-1H-pyrazole-3-carboxylate

C19H15F4N3O3

C19H15F4N3O3

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0℃; for 1h;92%
o-trifluoromethylbenzyl bromide
395-44-8

o-trifluoromethylbenzyl bromide

C14H14N2O3

C14H14N2O3

3-(4-(2-(trifluoromethyl)benzyl)piperazine-1-carbonyl)-2H-chromen-2-one

3-(4-(2-(trifluoromethyl)benzyl)piperazine-1-carbonyl)-2H-chromen-2-one

Conditions
ConditionsYield
With triethylamine In acetonitrile for 8h; Reflux;91%

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