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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 60410-16-4 with competitive price

Cas:60410-16-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:10 Kilogram

FOB Price: $100.0 / 120.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol 60410-16-4

Cas:60410-16-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

(1S,4R)-CIS-4-ACETOXY-2-CYCLOPENTEN-1-OL

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE CAS:60410-16-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE CAS:60410-16-4

Cas:60410-16-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(1R,3S)-(+)-4-Cyclopentene-1,3-diol 1-acetate

Cas:60410-16-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Saiwante (shanghai) New Material Technology Co., Ltd.

Appearance/Colour:white to light yellow solid Vapor Pressure:0.051mmHg at 25°C Melting Point:49-52 °C Refractive Index:1.5 Boiling Point:207.984 °C at 760 mmHg PKA:14.11±0.40(Predicted) Flash Point:83.718 °C PSA

Hot selling 60410-16-4 (1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:1 Gram

FOB Price: $2.0 / 5.0

Type:Trading Company

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Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

(1R,4S)-4-Hydroxycyclopent-2-en-1-yl acetate

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:1 Kilogram

FOB Price: $65.0 / 86.0

Type:Trading Company

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:1 Kilogram

Negotiable

Type:Other

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, higher purity,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, s

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol Application:(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

(1S,4R)-cis-4-Acetoxy-2-cyclopenten-1-ol

Cas:60410-16-4

Min.Order:0

Negotiable

Type:Other

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Synthetic route

cis-1,4-diacetoxy-2-cyclopentene
54664-61-8

cis-1,4-diacetoxy-2-cyclopentene

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With Novosyme sp 435 lipase In various solvent(s) at 20℃; for 18h; pH=8;96%
With Novozym 43596%
With lipase from candida antartica In aq. phosphate buffer at 20℃; for 24h; pH=8; Enzymatic reaction; enantioselective reaction;96%
cis-1,4-diacetoxy-2-cyclopentene
54664-61-8

cis-1,4-diacetoxy-2-cyclopentene

A

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With methanol; lipase B from Candida antarctica In tert-butyl methyl ether at 5℃; for 16h; Enzymatic reaction; enantioselective reaction;A n/a
B 95%
With sodium hydroxide; Esterase(porcine liver)PLE In water at 32℃; for 8h; Product distribution; further enzymes; pH=7, phosphate buffer;
With N-(2-acetamido)-2-aminoethanesulfonic acid; ethanolamine; 2-amino-2-hydroxymethyl-1,3-propanediol at 37℃; for 8h; Product distribution; antibody of IgG class: 37E8, pH 8.0; Km, Kcat, Ki; var. enzymes and time;
(-)-acetic acid cis-4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester
61305-31-5

(-)-acetic acid cis-4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol; ethyl acetate91%
cis-4-cyclopentene-1,3-diol
29783-26-4

cis-4-cyclopentene-1,3-diol

acetic anhydride
108-24-7

acetic anhydride

A

cis-1,4-diacetoxy-2-cyclopentene
54664-61-8

cis-1,4-diacetoxy-2-cyclopentene

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Stage #1: cis-4-cyclopentene-1,3-diol With (4-(pyridin-4-yl)-4,5-dihydro-3H-dinaphtho[2,1-c:1′,2′-e]azepine-2,6-diyl)bis(bis(4-((tertbutyldimethylsilyl)oxy)phenyl)methanol); N-ethyl-N,N-diisopropylamine In tert-butyl methyl ether at -40℃; for 0.25h;
Stage #2: acetic anhydride In tert-butyl methyl ether at -40℃; for 6h; Temperature; Time; enantioselective reaction;
A n/a
B 89%
cis-3,5-diacetoxycyclopentene

cis-3,5-diacetoxycyclopentene

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With Candida antartica lipase B In aq. phosphate buffer for 3.5h; pH=7; Enzymatic reaction;85%
(1R,4S)-4-[(tert-butyldimethylsilyl)oxy]-2-cyclopentene-1-yl acetate
115074-49-2

(1R,4S)-4-[(tert-butyldimethylsilyl)oxy]-2-cyclopentene-1-yl acetate

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride82%
vinyl acetate
108-05-4

vinyl acetate

cis-4-cyclopentene-1,3-diol

cis-4-cyclopentene-1,3-diol

A

cis-1,4-diacetoxy-2-cyclopentene
54664-61-8

cis-1,4-diacetoxy-2-cyclopentene

B

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

C

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
lipase EC 3.1.1.3 L10 In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity;A n/a
B 76.4%
C n/a
lipase EC 3.1.1.3 QLC In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity;A n/a
B 76.4%
C n/a
lipase EC 3.1.1.3 QL In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity;A n/a
B 75.5%
C n/a
lipase EC 3.1.1.3 QLG In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity;A n/a
B 61.9%
C n/a
pancreatin lipase In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity;A n/a
B 16.5%
C n/a
meso-cis-1,4-diacetoxy-2-cyclopentene
60389-71-1, 60410-14-2, 61826-75-3

meso-cis-1,4-diacetoxy-2-cyclopentene

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With novozyme 435 In aq. phosphate buffer at 4℃; for 18h; pH=6; pH-value; Temperature; Time; Enzymatic reaction;76%
With porcine liver esterase; phosphate buffer at 37℃; for 48h; pH=7.0; Hydrolysis;34%
With sodium hydroxide; Lipase PS Amano In water pH=7; Product distribution / selectivity; phosphate buffer; Enzymatic reaction;n/a
With sodium hydroxide; Novo SP435 In water pH=7; Product distribution / selectivity; phosphate buffer; Enzymatic reaction;
vinyl acetate
108-05-4

vinyl acetate

cis-4-cyclopentene-1,3-diol
29783-26-4

cis-4-cyclopentene-1,3-diol

A

cis-1,4-diacetoxy-2-cyclopentene
54664-61-8

cis-1,4-diacetoxy-2-cyclopentene

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran for 2.5h; Ambient temperature; Pancreatin as lipase;A 32%
B 65%
With triethylamine In tetrahydrofuran for 2h; Ambient temperature; Candida sp. 382 as lipase;A 40%
B 53%
vinyl acetate
108-05-4

vinyl acetate

cis-4-cyclopentene-1,3-diol
29783-26-4

cis-4-cyclopentene-1,3-diol

A

cis-1,4-diacetoxy-2-cyclopentene
54664-61-8

cis-1,4-diacetoxy-2-cyclopentene

B

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

C

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; for 23h; Enzymatic reaction; enantioselective reaction;A 25%
B 61%
C n/a
2,2,2-trichloroethyl acetate
625-24-1

2,2,2-trichloroethyl acetate

cis-4-cyclopentene-1,3-diol
29783-26-4

cis-4-cyclopentene-1,3-diol

A

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
pancreatin/base;

A

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

B

(1R,4R)-(+)-4-Hydroxy-2-cyclopentenyl acetate
60410-17-5

(1R,4R)-(+)-4-Hydroxy-2-cyclopentenyl acetate

Conditions
ConditionsYield
With potassium hydroxide; pig pancreatic lipase at 37℃; for 8h; 0.1 M phosphate buffer (pH 7); Yield given. Yields of byproduct given;
Acetic acid (1R,4S)-4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester
142130-74-3

Acetic acid (1R,4S)-4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol for 2h; Ambient temperature; Yield given;
(1S,4R)-(-)-4-(2'R*-tetrahydropyranyloxy)-2-cyclopentenyl acetate
95722-35-3

(1S,4R)-(-)-4-(2'R*-tetrahydropyranyloxy)-2-cyclopentenyl acetate

A

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol for 2h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
C9H9(2)H3O4

C9H9(2)H3O4

A

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

B

C7H7(2)H3O3

C7H7(2)H3O3

Conditions
ConditionsYield
With porcine liver esterase Hydrolysis;
acetic anhydride
108-24-7

acetic anhydride

/PXFCB296--150/

/PXFCB296--150/

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
(1R,4S)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enol
120520-91-4

(1R,4S)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enol

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 99 percent / Et3N; DMAP
2: 82 percent / TBAF
View Scheme
(2-furyl)methyl alcohol
98-00-0

(2-furyl)methyl alcohol

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 53 percent / KH2PO4, H3PO4 / H2O / 40 h / 99 °C / pH 4.1
2: 76 percent / PPTs / tetrahydrofuran / 18 h / Ambient temperature
3: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C
4: 50 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
5: DMAP / pyridine / 16 h / Ambient temperature
6: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: 53 percent / KH2PO4, H3PO4 / H2O / 40 h / 99 °C / pH 4.1
2: 76 percent / PPTs / tetrahydrofuran / 18 h / Ambient temperature
3: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C
4: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
5: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 4 steps
1: potassium dihydrogenphosphate; phosphoric acid / water / 22 h / 25 - 99 °C / pH 4.1
2: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 2 h / -70 - -60 °C
3: dmap; triethylamine / N,N-dimethyl-formamide / 16 h / 10 - 30 °C / Inert atmosphere
4: disodium hydrogenphosphate / water / 14 h / 25 - 30 °C / pH 7 / Enzymatic reaction
View Scheme
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 76 percent / PPTs / tetrahydrofuran / 18 h / Ambient temperature
2: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C
3: 50 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
4: DMAP / pyridine / 16 h / Ambient temperature
5: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 4 steps
1: 76 percent / PPTs / tetrahydrofuran / 18 h / Ambient temperature
2: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C
3: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
4: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 2 h / -70 - -60 °C
2: dmap; triethylamine / N,N-dimethyl-formamide / 16 h / 10 - 30 °C / Inert atmosphere
3: disodium hydrogenphosphate / water / 14 h / 25 - 30 °C / pH 7 / Enzymatic reaction
View Scheme
(1R,4S)-(-)-4-(2'R*-tetrahydropyranyloxy)-2-cyclopentenol
63640-56-2

(1R,4S)-(-)-4-(2'R*-tetrahydropyranyloxy)-2-cyclopentenol

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: DMAP / pyridine / 16 h / Ambient temperature
2: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enone
61305-37-1, 62356-78-9, 70615-05-3

4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enone

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C
2: 50 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
3: DMAP / pyridine / 16 h / Ambient temperature
4: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C
2: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
3: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 50 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
2: DMAP / pyridine / 16 h / Ambient temperature
3: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature
2: p-TsOH / ethanol / 2 h / Ambient temperature
View Scheme
cis-4-cyclopentene-1,3-diol
29783-26-4

cis-4-cyclopentene-1,3-diol

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dmap; triethylamine / N,N-dimethyl-formamide / 16 h / 10 - 30 °C / Inert atmosphere
2: disodium hydrogenphosphate / water / 14 h / 25 - 30 °C / pH 7 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / tetrahydrofuran / 23 h / 20 °C / Enzymatic reaction
2: lipase from candida antartica / aq. phosphate buffer / 24 h / 20 °C / pH 8 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / tetrahydrofuran / 24 h / 20 °C / Enzymatic reaction
2: lipase from candida antartica / aq. phosphate buffer / 24 h / 20 °C / pH 8 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: triethylamine; lipase from candida antartica / tetrahydrofuran / 0.5 h / 20 °C / Enzymatic reaction
2: lipase from candida antartica / aq. phosphate buffer / 24 h / 20 °C / pH 8 / Enzymatic reaction
View Scheme
6-oxabicyclo[3.1.0]hex-2-ene
7129-41-1

6-oxabicyclo[3.1.0]hex-2-ene

acetic acid
64-19-7

acetic acid

A

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); Triethylene glycol dimethyl ether In tetrahydrofuran at 0℃; for 1h; Reagent/catalyst; Solvent; Schlenk technique; Inert atmosphere; Overall yield = 85 %Chromat.;A n/a
B n/a
cyclopenta-1,3-diene
542-92-7

cyclopenta-1,3-diene

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: (-)-chloro((1R,2R)-4,4',6,6'-tetra-tert-butyl-2,2'-[cyclohexane-1,2-diylbis(nitrilomethylidyne)]diphenolato)manganese(III); 4-Phenylpyridine 1-oxide; sodium hypochlorite / dichloromethane / 5 h / 4 °C
2: Triethylene glycol dimethyl ether; tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 1 h / 0 °C / Schlenk technique; Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: oxygen; thiourea; Rose Bengal lactone / methanol / 19 °C / 6000.6 Torr / Irradiation
2: dmap; pyridine / 2 h / 0 - 7 °C / Inert atmosphere
3: novozyme 435 / aq. phosphate buffer / 18 h / 4 °C / pH 6 / Enzymatic reaction
View Scheme
cis-1,4-diacetoxy-2-cyclopentene
54664-61-8

cis-1,4-diacetoxy-2-cyclopentene

A

cis-4-cyclopentene-1,3-diol
29783-26-4

cis-4-cyclopentene-1,3-diol

B

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

C

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With pseudomonas fluorescens lipase In hexane; water at 25℃; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;
With lipase B from Candida antarctica In aq. phosphate buffer at 20℃; pH=7.5; Solvent; Enzymatic reaction;A n/a
B n/a
C n/a
cis-4-cyclopentene-1,3-diol diacetate

cis-4-cyclopentene-1,3-diol diacetate

A

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
60176-77-4

(1S,4R)-4-hydroxy-2-cyclopentenyl acetate

B

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With recombinant pig liver esterase In aq. phosphate buffer at 50℃; for 2h; pH=7.5; pH-value; Temperature; Solvent; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
cis-3-acetoxy-5-hydroxycyclopent-1-ene
61740-26-9

cis-3-acetoxy-5-hydroxycyclopent-1-ene

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1H-imidazole / dichloromethane / 0.17 h / 0 - 23 °C
2: Novozym 435 lipase / dichloromethane; aq. phosphate buffer / 23 - 24 °C / pH 8.0
View Scheme
6-oxabicyclo[3.1.0]hex-2-ene
7129-41-1

6-oxabicyclo[3.1.0]hex-2-ene

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 0.33 h / 0 °C
2: 1H-imidazole / dichloromethane / 0.17 h / 0 - 23 °C
3: Novozym 435 lipase / dichloromethane; aq. phosphate buffer / 23 - 24 °C / pH 8.0
View Scheme
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Acetic acid (1R,4S)-4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester
142130-74-3

Acetic acid (1R,4S)-4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester

Conditions
ConditionsYield
With toluene-4-sulfonic acid for 0.166667h; Ambient temperature;100%
With pyridinium p-toluenesulfonate In dichloromethane96%
With TSA In dichloromethane at 0℃; for 0.166667h;91%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

diethyl chlorophosphate
814-49-3

diethyl chlorophosphate

(1S,4R)-4-acetoxy-2-cyclopenten-1-yl diethyl phosphate
594857-54-2

(1S,4R)-4-acetoxy-2-cyclopenten-1-yl diethyl phosphate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 25℃; for 4.5h;100%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(1R,4S)-4-[(tert-butyldimethylsilyl)oxy]-2-cyclopentene-1-yl acetate
115074-49-2

(1R,4S)-4-[(tert-butyldimethylsilyl)oxy]-2-cyclopentene-1-yl acetate

Conditions
ConditionsYield
With 1H-imidazole In tetrahydrofuran at 20℃;100%
With 1H-imidazole In tetrahydrofuran at 20℃; for 24h;100%
With 1H-imidazole In tetrahydrofuran at 20℃; for 24h;100%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

pivaloyl chloride
3282-30-2

pivaloyl chloride

(3R,5S)-(+)-3-acetoxy-5-(trimethylacetyloxy)cyclopent-1-ene
178034-11-2

(3R,5S)-(+)-3-acetoxy-5-(trimethylacetyloxy)cyclopent-1-ene

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0℃; for 2h;100%
With dmap; triethylamine In dichloromethane at 0℃;99%
With dmap; triethylamine In dichloromethane at 0℃; for 0.75h;98%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

Acetic acid (1R,4R)-4-methanesulfonyloxy-cyclopent-2-enyl ester
177566-46-0

Acetic acid (1R,4R)-4-methanesulfonyloxy-cyclopent-2-enyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane Ambient temperature;100%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

1H-benzotriazole-1-carboxylic acid methyl ester 3-oxide
76266-27-8

1H-benzotriazole-1-carboxylic acid methyl ester 3-oxide

Acetic acid (1R,4S)-4-methoxycarbonyloxy-cyclopent-2-enyl ester

Acetic acid (1R,4S)-4-methoxycarbonyloxy-cyclopent-2-enyl ester

Conditions
ConditionsYield
With dmap; triethylamine In pyridine at 25℃;99%
N-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)-N-[2-{[(2S,3R,6S)-2-methoxy-6-{(2-nitrophenylsulfonamido)methyl}-3,6-dihydro-2H-pyran-3-yloxy]methyl}allyl]-4-methylbenzenesulfonamide
1120367-44-3

N-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)-N-[2-{[(2S,3R,6S)-2-methoxy-6-{(2-nitrophenylsulfonamido)methyl}-3,6-dihydro-2H-pyran-3-yloxy]methyl}allyl]-4-methylbenzenesulfonamide

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

C41H40F17N3O11S2
1252933-09-7

C41H40F17N3O11S2

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0 - 20℃; Fukuyama-Mitsunobu reaction;98%
N-allyl-p-nitrobenzenesulfonamide
100704-44-7

N-allyl-p-nitrobenzenesulfonamide

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

C16H18N2O6S
1449016-83-4

C16H18N2O6S

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 18h; Fukuyama Coupling;98%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

methyl chloroformate
79-22-1

methyl chloroformate

methyl (1S,4R)-4-acetoxy-2-cyclopentenylcarbonate
138318-67-9

methyl (1S,4R)-4-acetoxy-2-cyclopentenylcarbonate

Conditions
ConditionsYield
With pyridine In dichloromethane at 23℃;97%
With pyridine In dichloromethane at 0℃; for 2h;97%
With pyridine In dichloromethane at 0℃; for 1h;
Allylchlorodimethylsilane
4028-23-3

Allylchlorodimethylsilane

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

(1R,4S)-acetic acid 4-(allyldimethylsilanyloxy)cyclopent-2-enyl ester

(1R,4S)-acetic acid 4-(allyldimethylsilanyloxy)cyclopent-2-enyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 25℃; for 3h; Substitution;97%
<2-(13)C>acetyl chloride
14770-40-2

<2-(13)C>acetyl chloride

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

(1S,4R)-cis-1-(2-13C-acetoxy)-4-acetoxycyclopent-2-ene

(1S,4R)-cis-1-(2-13C-acetoxy)-4-acetoxycyclopent-2-ene

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃;97%
diiodomethane
75-11-6

diiodomethane

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

(1S,2R,4S,5R)-(+)-4-hydroxybicyclo<3.1.0>hex-2-yl acetate
137820-15-6

(1S,2R,4S,5R)-(+)-4-hydroxybicyclo<3.1.0>hex-2-yl acetate

Conditions
ConditionsYield
Stage #1: (1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate With Et2Zn In dichloromethane at 0℃; for 0.25h; Simmons-Smith cyclopropanation;
Stage #2: diiodomethane With Et2Zn In hexane; dichloromethane at 0 - 20℃;
97%
Stage #1: (1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate With diethylzinc In hexane; dichloromethane at 0℃;
Stage #2: diiodomethane With diethylzinc In hexane; dichloromethane at 0 - 20℃;
N-[(2R)-1-{[(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)bis(propan-2-yl)silyl]oxy}pent-4-en-2-yl]-2-nitrobenzene-1-sulfonamide

N-[(2R)-1-{[(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)bis(propan-2-yl)silyl]oxy}pent-4-en-2-yl]-2-nitrobenzene-1-sulfonamide

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

(1R,4R)-4-(N-((R)-1-((3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)diisopropylsilyloxy)-pent-4-en-2-yl)-2-nitrophenylsulfonamido)cyclopent-2-enyl acetate

(1R,4R)-4-(N-((R)-1-((3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)diisopropylsilyloxy)-pent-4-en-2-yl)-2-nitrophenylsulfonamido)cyclopent-2-enyl acetate

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0 - 20℃; Fukuyama Coupling; Inert atmosphere;97%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

(1S,4R)-cis-1-ethoxycarbonyloxy-4-acetoxy-2-cyclopentene
128741-00-4

(1S,4R)-cis-1-ethoxycarbonyloxy-4-acetoxy-2-cyclopentene

Conditions
ConditionsYield
With pyridine at 0℃; for 1h;96.6%
With pyridine In dichloromethane for 2h; Ambient temperature;92%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

(R)-4-acetoxycyclopent-2-en-1-one
59995-48-1

(R)-4-acetoxycyclopent-2-en-1-one

Conditions
ConditionsYield
With dipyridinium dichromate96%
With oxalyl dichloride; dimethyl sulfoxide; triethylamine In dichloromethane94%
With oxalyl dichloride; dimethyl sulfoxide; triethylamine In dichloromethane at -78℃; Swern oxidation;94%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

acetic anhydride
108-24-7

acetic anhydride

ethyl 2-<(1R,4S)-4-(acetyloxy)-2-cyclopentenyl>-4-tert-butoxy-3-oxobutanoate

ethyl 2-<(1R,4S)-4-(acetyloxy)-2-cyclopentenyl>-4-tert-butoxy-3-oxobutanoate

Conditions
ConditionsYield
With dmap In dichloromethane at 0℃; for 4h;95%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

chloromethyl methyl ether
107-30-2

chloromethyl methyl ether

Acetic acid (1R,4S)-4-methoxymethoxy-cyclopent-2-enyl ester
198021-31-7

Acetic acid (1R,4S)-4-methoxymethoxy-cyclopent-2-enyl ester

Conditions
ConditionsYield
With dmap; N-ethyl-N,N-diisopropylamine95%
78%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

2,2,2-Trichloro-acetimidic acid (2R,3R,4S,5S,6R)-6-methyl-3,4,5-tris-triethylsilanyloxy-tetrahydro-pyran-2-yl ester
237763-47-2

2,2,2-Trichloro-acetimidic acid (2R,3R,4S,5S,6R)-6-methyl-3,4,5-tris-triethylsilanyloxy-tetrahydro-pyran-2-yl ester

Acetic acid (1R,4S)-4-((2S,3R,4S,5S,6R)-6-methyl-3,4,5-tris-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester

Acetic acid (1R,4S)-4-((2S,3R,4S,5S,6R)-6-methyl-3,4,5-tris-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-cyclopent-2-enyl ester

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In diethyl ether at -30℃; Etherification;95%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

(1S,4R)-Cis-1-methanesulfonyloxy-4-acetoxy-2-cyclopentene

(1S,4R)-Cis-1-methanesulfonyloxy-4-acetoxy-2-cyclopentene

Conditions
ConditionsYield
With triethylamine In dichloromethane95%
With triethylamine In dichloromethane95%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

1(R)-acetoxy-2,3(R,R),4(S)-trihydroxycyclopentane
114739-33-2

1(R)-acetoxy-2,3(R,R),4(S)-trihydroxycyclopentane

Conditions
ConditionsYield
With osmium(VIII) oxide; 4-methylmorpholine N-oxide In water; acetone94%
-butyl vinyl ether
111-34-2

-butyl vinyl ether

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Acetic acid (1R,4S)-4-(1-butoxy-2-iodo-ethoxy)-cyclopent-2-enyl ester
879098-65-4

Acetic acid (1R,4S)-4-(1-butoxy-2-iodo-ethoxy)-cyclopent-2-enyl ester

Conditions
ConditionsYield
With N-iodo-succinimide In dichloromethane at 20℃; for 20h;93%
Benzyloxymethyl chloride
3587-60-8

Benzyloxymethyl chloride

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

(1S)-cis-4-Benzyloxymethylcyclopent-2-en-1-ol
934986-75-1

(1S)-cis-4-Benzyloxymethylcyclopent-2-en-1-ol

Conditions
ConditionsYield
Stage #1: Benzyloxymethyl chloride With bromine; magnesium; mercury dichloride In tetrahydrofuran at -5℃; for 2.5h;
Stage #2: (1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate In tetrahydrofuran at -20℃; for 0.25h; Further stages.;
92%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

sodium salt of di-tert-butyl iminodicarboxylate

sodium salt of di-tert-butyl iminodicarboxylate

di-tert-butyl [(1R,4S)-4-hydroxycyclopent-2-en-1-yl]imidodicarbonate
220241-57-6

di-tert-butyl [(1R,4S)-4-hydroxycyclopent-2-en-1-yl]imidodicarbonate

Conditions
ConditionsYield
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran92%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

ethyl vinyl ether
109-92-2

ethyl vinyl ether

Acetic acid (1R,4S)-4-(1-ethoxy-2-iodo-ethoxy)-cyclopent-2-enyl ester

Acetic acid (1R,4S)-4-(1-ethoxy-2-iodo-ethoxy)-cyclopent-2-enyl ester

Conditions
ConditionsYield
With N-iodo-succinimide In dichloromethane at -20℃; for 4h;90%
With N-iodo-succinimide
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

2-<(1R,4S)-4-hydroxycyclopent-2-enyl>malonsaeure-dimethylester
120052-50-8

2-<(1R,4S)-4-hydroxycyclopent-2-enyl>malonsaeure-dimethylester

Conditions
ConditionsYield
With potassium tert-butylate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 20℃; for 2h;90%
With potassium tert-butylate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 20℃; for 2h; Product distribution; Further Variations:; Reagents; Temperatures; reaction times;90%
With potassium carbonate; triphenylphosphine; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 40℃; for 12h;73%
With tetrakis(triphenylphosphine) palladium(0); sodium hydride; triphenylphosphine 1.) THF, 2.) 1 h; Yield given. Multistep reaction;
With potassium tert-butylate; palladium
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

4-nitro-benzoic acid
62-23-7

4-nitro-benzoic acid

p-Nitrobenzoic acid (1R,4R)-4-acetoxycyclopent-2-en-1-yl ester
289716-57-0

p-Nitrobenzoic acid (1R,4R)-4-acetoxycyclopent-2-en-1-yl ester

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Esterification; Mitsunobu reaction;90%
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
60410-16-4

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

chloroacetic acid
79-11-8

chloroacetic acid

(1R,4R)-4-acetoxycyclopent-2-en-1-yl chloroacetate
859509-52-7

(1R,4R)-4-acetoxycyclopent-2-en-1-yl chloroacetate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 2h;90%

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