Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap
Cas:6052-73-9
Min.Order:1 Kilogram
FOB Price: $5.0
Type:Manufacturers
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:6052-73-9
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:6052-73-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry5,6-dihydro-1H-pyridin-2-one CAS:6052-73-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ
Cas:6052-73-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:6052-73-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:6052-73-9
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Trading Company
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirybest seller Application:API
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBest quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryCas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:5mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
High quality suppliers Application:healing drugs
Cas:6052-73-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP
Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical
1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
Cas:6052-73-9
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiry6-oxo-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With hydrogenchloride In methanol; water at 0℃; for 1h; Inert atmosphere; | 98% |
With trifluoroacetic acid In dichloromethane at 0 - 20℃; for 2h; | 72% |
With trifluoroacetic acid In dichloromethane at 20℃; Inert atmosphere; |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With dihydrogen peroxide In tetrahydrofuran at 0 - 20℃; for 2h; | 97.7% |
In tetrahydrofuran at 0 - 20℃; for 2h; | 0.55 g |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In dichloromethane for 2h; Reflux; | 94% |
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In dichloromethane at 40℃; for 2h; | 56% |
3-(phenylthio)piperidin-2-one
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: 3-(phenylthio)piperidin-2-one With sodium hydrogencarbonate In dichloromethane for 0.166667h; Stage #2: With 3-chloro-benzenecarboperoxoic acid for 1h; Further stages.; | 90% |
Stage #1: 3-(phenylthio)piperidin-2-one With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 20℃; for 2h; Stage #2: In toluene for 1h; Reflux; | 80% |
Multi-step reaction with 2 steps 1: m-CPBA, aq.NaHCO3 / CH2Cl2 / 1 h / 0 °C 2: 1.17 g / benzene / 1 h / Heating View Scheme |
N-(but-3-en-1-yl)prop-2-enamide
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In toluene at 85 - 90℃; for 7h; | 75% |
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In dichloromethane for 6h; Grubbs Olefin Metathesis; Reflux; | 70% |
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In dichloromethane for 6h; Reflux; | 70% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
at 260℃; under 1 Torr; | 68% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With lithium hydroxide monohydrate In tetrahydrofuran at 50℃; for 4h; | 68% |
(E)-2,4-pentadienoic acid
A
5,6-dihydro-2(1H)-pyridinone
B
1,6-dihydropyridin-2(3H)-one
Conditions | Yield |
---|---|
With ammonia Yield given. Yields of byproduct given; |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
In benzene for 1h; Heating; | 1.17 g |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With dihydrogen peroxide In tetrahydrofuran 1.) 0 deg C, 30 min, 2.) 25 deg C, 1.5 h; Yield given; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: LDA / tetrahydrofuran; hexane / 1.) -50 deg C, 45 min, 2.) -78 deg C, 7 h 2: 50percent H2O2 / tetrahydrofuran / 1.) 0 deg C, 30 min, 2.) 25 deg C, 1.5 h View Scheme | |
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran / 0.75 h / -50 °C / Inert atmosphere 1.2: 7 h / -78 °C / Inert atmosphere 2.1: dihydrogen peroxide / tetrahydrofuran / 2 h / 0 - 20 °C View Scheme |
1-(methoxymethyl)-3-(phenylthio)piperidin-2-one
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 78 percent / conc.HCl / ethanol / 6 h / Heating 2: m-CPBA, aq.NaHCO3 / CH2Cl2 / 1 h / 0 °C 3: 1.17 g / benzene / 1 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1.1: hydrogenchloride / ethanol; water / 6 h / Reflux 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 20 °C 2.2: 1 h / Reflux View Scheme |
A
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With 4-methyl-morpholine In 1,4-dioxane at 80℃; for 18h; | A 6 mg B 36 mg |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride Grubbs Olefin Metathesis; |
2-oxopiperidine-1-carboxylic acid tert-butyl ester
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere 1.2: 1.5 h / Inert atmosphere 2.1: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere 2.2: 3 h / 80 °C / Inert atmosphere 3.1: hydrogenchloride / methanol; water / 1 h / 0 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 4 steps 1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere 1.2: 1.5 h / -78 °C / Inert atmosphere 2.1: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 2 h / 0 °C 3.1: toluene / 3 h / 80 °C 4.1: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C View Scheme |
N-(tert-butyloxycarbonyl)-3-(phenylthio)piperidine-2-one
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere 1.2: 3 h / 80 °C / Inert atmosphere 2.1: hydrogenchloride / methanol; water / 1 h / 0 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 2 h / 0 °C 2: toluene / 3 h / 80 °C 3: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere 1.2: 16 h / 20 °C / Inert atmosphere 2.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere 2.2: 1.5 h / Inert atmosphere 3.1: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere 3.2: 3 h / 80 °C / Inert atmosphere 4.1: hydrogenchloride / methanol; water / 1 h / 0 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: triethylamine / dichloromethane / 13 h / 0 - 20 °C 2: 2,5-di-tert-butyl-p-benzoquinone; palladium(II) trifluoroacetate; racemic methyl phenyl sulfoxide; zinc(II) trifluoroacetate; di-n-butylboryl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / dichloromethane; 1,4-dioxane / 24 h / 20 °C / Inert atmosphere; Sealed tube 3: lithium hydroxide monohydrate / tetrahydrofuran / 4 h / 50 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: triethylamine / toluene / 4 h / Inert atmosphere 2.1: tetrahydrofuran / 0.75 h / -50 °C / Alkaline conditions; Enzymatic reaction 2.2: 7 h 3.1: tetrahydrofuran / 2 h / 0 - 20 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: triethylamine / toluene / 4 h / 50 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran / 0.75 h / -50 °C / Inert atmosphere 2.2: 7 h / -78 °C / Inert atmosphere 3.1: dihydrogen peroxide / tetrahydrofuran / 2 h / 0 - 20 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: n-butyllithium / dichloromethane; tetrahydrofuran / 0.5 h / 0 °C 1.2: 3 h 2.1: lithium diisopropyl amide / tetrahydrofuran / 0.75 h / -78 °C / Inert atmosphere 2.2: -78 - 20 °C 3.1: hydrogenchloride / ethanol; water / 6 h / Reflux 4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 20 °C 4.2: 1 h / Reflux View Scheme |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 2,5-di-tert-butyl-p-benzoquinone; palladium(II) trifluoroacetate; racemic methyl phenyl sulfoxide; zinc(II) trifluoroacetate; di-n-butylboryl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / dichloromethane; 1,4-dioxane / 24 h / 20 °C / Inert atmosphere; Sealed tube 2: lithium hydroxide monohydrate / tetrahydrofuran / 4 h / 50 °C View Scheme |
1-(methoxymethyl)piperidin-2-one
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: lithium diisopropyl amide / tetrahydrofuran / 0.75 h / -78 °C / Inert atmosphere 1.2: -78 - 20 °C 2.1: hydrogenchloride / ethanol; water / 6 h / Reflux 3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 20 °C 3.2: 1 h / Reflux View Scheme |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: toluene / 3 h / 80 °C 2: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C View Scheme |
5,6-dihydro-2(1H)-pyridinone
cis-3,4-dihydroxy-2-piperidinone
Conditions | Yield |
---|---|
osmium(VIII) oxide; 4-methylmorpholine N-oxide In tert-butyl alcohol Ambient temperature; | 100% |
With osmium(VIII) oxide; 4-methylmorpholine N-oxide In tert-butyl alcohol for 27h; Ambient temperature; | 64 mg |
[2-(hydroxymethyl)phenyl]dimethyl(4-fluorophenyl)silane
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
With potassium hydroxide; (1R,4R)-2,5-diphenylbicyclo[2.2.2]octa-2,5-diene; bis(ethylene)rhodium(I) chloride dimer In tetrahydrofuran at 50℃; for 12h; | 92% |
Conditions | Yield |
---|---|
With (R)-2,2'-bis(diarylphosphino)-1,1'-binaphthyl; water; bis(ethylene)rhodium acetylacetonate In 1,4-dioxane at 60℃; for 12h; | 88% |
Conditions | Yield |
---|---|
With (R)-2,2'-bis(diphenylphosphino)-octahydro-1,1'-binaphthyl; water; bis(ethylene)rhodium acetylacetonate In 1,4-dioxane at 40℃; for 12h; | 84% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With sodium hydride In tetrahydrofuran; mineral oil at -5 - 0℃; for 2h; Stage #2: C13H11ClN2O In tetrahydrofuran; mineral oil for 21h; | 82% |
With triethylamine In tetrahydrofuran at 0℃; for 3h; |
Conditions | Yield |
---|---|
With titanium tetrachloride; triethylamine In dichloromethane at 0℃; for 1h; | 76% |
Conditions | Yield |
---|---|
In toluene at 20 - 80℃; for 12h; Inert atmosphere; Molecular sieve; | 75% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 10h; | 75% |
5,6-dihydro-2(1H)-pyridinone
1-chloro-5,6-dihydropyridin-2(1H)-one
Conditions | Yield |
---|---|
With N-chloro-succinimide; potassium tert-butylate In tetrahydrofuran at 20℃; for 0.666667h; Inert atmosphere; | 74% |
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.25h; Stage #2: p-phenylenediacrylic diacid dichloride In tetrahydrofuran; hexane at -78℃; for 3h; | 72% |
5,6-dihydro-2(1H)-pyridinone
2-Nitrobenzenesulfonyl chloride
1-nosyl-5,6-dihydropyridin-2(1H)-one
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere; Stage #2: 2-Nitrobenzenesulfonyl chloride In tetrahydrofuran; hexane at -78℃; for 1.5h; Inert atmosphere; | 71% |
Conditions | Yield |
---|---|
titanium tetrachloride In 1,3,5-trimethyl-benzene for 74h; Heating; | 68.9% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Stage #2: C19H31NO5 In tetrahydrofuran at -78 - 20℃; for 1h; | 67.8% |
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Stage #2: C19H31NO5 In tetrahydrofuran at 20℃; for 1h; | 67.8% |
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With sodium hydride In tetrahydrofuran at 0℃; for 1h; Inert atmosphere; Stage #2: chloroacetyl chloride In tetrahydrofuran at 0 - 20℃; Inert atmosphere; | 65% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 10h; | 65% |
5,6-dihydro-2(1H)-pyridinone
cinnamyl chloride
1-cinnamoyl-5,6-dihydropyridin-2(1H)-one
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With sodium hydride In tetrahydrofuran at 0℃; for 0.25h; Inert atmosphere; Stage #2: cinnamyl chloride In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere; | 64% |
Conditions | Yield |
---|---|
In benzene at 20℃; for 504000h; Cycloaddition; | 62% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: C10H11ClN2O With pivaloyl chloride; triethylamine In tetrahydrofuran at -20℃; for 0.75h; Stage #2: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran at -70℃; for 1.75h; | 53% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: (2E)-3-(3,5,6-trimethylpyrazin-2-yl)prop-2-enoic acid With pivaloyl chloride; triethylamine In tetrahydrofuran; dichloromethane at -20℃; Stage #2: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran for 1h; | 53% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Stage #2: (E)-(E)-3-(5-methoxypyrimidin-2-yl)acrylic pivalic anhydride In tetrahydrofuran; hexane at -78℃; for 1h; | 52.23% |
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Stage #2: (E)-(E)-3-(5-methoxypyrimidin-2-yl)acrylic pivalic anhydride In tetrahydrofuran; hexane at -78℃; for 1h; | 52.23% |
Conditions | Yield |
---|---|
With triethylamine In benzene at 20℃; for 48h; Cycloaddition; dehydrochlorination; | 51% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Stage #2: C19H31NO5 In tetrahydrofuran at -78 - 20℃; for 1h; | 49.6% |
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Stage #2: C19H31NO5 In tetrahydrofuran at 20℃; for 1h; | 49.6% |
5,6-dihydro-2(1H)-pyridinone
Conditions | Yield |
---|---|
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Stage #2: (E)-(E)-3-(3,5-dimethyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)acrylic pivalic anhydride In tetrahydrofuran; hexane at -78℃; for 1.5h; | 48.92% |
Stage #1: 5,6-dihydro-2(1H)-pyridinone With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Stage #2: (E)-(E)-3-(3,5-dimethyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)acrylic pivalic anhydride In tetrahydrofuran at -78℃; for 1.5h; | 48.92% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View