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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Chlorobutyronitrile supplier in China

Cas:628-20-6

Min.Order:0 Metric Ton

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Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for 4-Chlorobutyronitrile Cas 628-20-6 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Liquid Storage:Refrigerator Package:1kg/foil bag, 25kg/drum

Wholesale best purity 4-Chlorobutyronitrile Cas 628-20-6 with low price high quality

Cas:628-20-6

Min.Order:1 Kilogram

FOB Price: $115.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1

Negotiable

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for t

High purity 4-Chlorobutyronitrile 98% TOP1 supplier in China

Cas:628-20-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: 4-Chlorobutyronitrile Synonyms: GAMMA-CHLOROPROPYL CYANIDE;4-CHLOROBUTYRONITRILE;4-CHLOROBUTANENITRILE;4-chloro-butanenitril;4-chloro-butyronitril;Butyronitrile, 4-chloro-;gamma-Chlorobutyronitrile;4-CHLOROBUTYRONITRILE 99% (GC) CAS

4-Chlorobutyronitrile 628-20-6

Cas:628-20-6

Min.Order:1 Kilogram

FOB Price: $500.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 628-20-6 with best quality

Cas:628-20-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Synonyms:Gamma-chloropropyl cyanide; 4-chlorobutyronitrile; 4-chlorobutanenitrile; 4-chloro-butanenitril; 4-chloro-butyronitril; butyronitrile, 4-chloro-; gamma-chlorobutyronitrile; butanenitrile, 4-chloro-; 1-chloro-3-cyanopropane; chlorobutyronit

4-chlorobutytonitrile

Cas:628-20-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Butanenitrile,4-chloro- 628-20-6

Cas:628-20-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

intermediate, 4-Chlorobutyronitrile CAS:628-20-6

Cas:628-20-6

Min.Order:1 Kilogram

FOB Price: $90.0 / 98.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

4-Chlorobutyronitrile CAS:628-20-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

4-Chlorobutyronitrile CAS:628-20-6

Cas:628-20-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Butanenitrile,4-chloro-

Cas:628-20-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Butanenitrile,4-chloro-/ LIDE PHARMA- Factory supply / Best price

Cas:628-20-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:628-20-6

Cas:628-20-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity 4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:0

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

4-Chlorobutyronitrile Chemical Properties Boiling point 195-197 °C (lit.) density 1.095 g/mL at 20 °C refractive index n20/D 1.442(lit.) Fp 185 °F storage temp. Refrigerator form Liquid color Clear colorless to

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Gram

Negotiable

Type:Other

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Kilogram

Negotiable

Type:Other

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-Chlorobutyronitrile

Cas:628-20-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:Colorless liquid Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Chlorobutyronitrile cas no. 628-20-6 98%

Cas:628-20-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-chlorobutytonitrile

Cas:628-20-6

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

1-chloro-4,4-dihydroxy-4-butylamine

1-chloro-4,4-dihydroxy-4-butylamine

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With aluminum oxide; calcium hydroxide; 2-hydroxynitrobenzene In cyclohexane at 77 - 97℃; for 5.5h; Temperature; Reflux;92%
4-chlorobutyramide
2455-04-1

4-chlorobutyramide

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With formaldehyd; formic acid; acetonitrile for 12h; Heating;87%
2-((cyclobutylideneamino)oxy)-2-methylpropanoic acid

2-((cyclobutylideneamino)oxy)-2-methylpropanoic acid

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With N-chloro-succinimide; potassium acetate; 9-(2-mesityl)-10-methylacridinium perchlorate In acetonitrile at 20℃; for 1h; Irradiation; Sealed tube; Inert atmosphere;59%
5-chloro-valeric acid
1119-46-6

5-chloro-valeric acid

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With trifluoroacetic acid; trifluoroacetic anhydride; sodium nitrite at 20℃; nitrosative cleavage;57%
propyl cyanide
109-74-0

propyl cyanide

A

3-chlorobutyronitrile
53778-71-5

3-chlorobutyronitrile

B

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With chlorine Irradiation.mit UV-Licht;
With sodium persulfate; copper dichloride In water at 85 - 90℃; for 10h; Yield given. Yields of byproduct given;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;
hydroxymethyl propionamide
927-60-6

hydroxymethyl propionamide

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With thionyl chloride; benzene
With trichlorophosphate; benzene
With phosphorus trichloride
ethanol
64-17-5

ethanol

sodium cyanide
143-33-9

sodium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

4-bromobutanenitrile
5332-06-9

4-bromobutanenitrile

ethanol
64-17-5

ethanol

potassium cyanide
151-50-8

potassium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

Glutaronitrile
544-13-8

Glutaronitrile

sodium cyanide
143-33-9

sodium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

Glutaronitrile
544-13-8

Glutaronitrile

Conditions
ConditionsYield
With methanol
potassium cyanide
151-50-8

potassium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With ethanol
With ethanol; water Alkohol abdestillieren,Wasser zum Rueckstand geben,abgeschiedene Oelschicht abheben und fraktionieren;
1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

4-butanolide
96-48-0

4-butanolide

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
(i) liq. NH3, (ii) SOCl2; Multistep reaction;
tetraethylammoniumcyanide
13435-20-6

tetraethylammoniumcyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
In dichloromethane
2,4-dichlorobutanenitrile
77100-86-8

2,4-dichlorobutanenitrile

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With acetic acid; zinc for 2h; Yield given;
1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

alcoholic KCN

alcoholic KCN

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

propyl cyanide
109-74-0

propyl cyanide

chlorine
7782-50-5

chlorine

A

3-chlorobutyronitrile
53778-71-5

3-chlorobutyronitrile

B

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
mit UV-Licht in der Dampfphase.Irradiation;
propyl cyanide
109-74-0

propyl cyanide

chlorine
7782-50-5

chlorine

A

3-chlorobutyronitrile
53778-71-5

3-chlorobutyronitrile

B

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

C

2-chlorobutyronitrile
4158-37-6

2-chlorobutyronitrile

Conditions
ConditionsYield
at 450℃; Dampfphase;
propyl cyanide
109-74-0

propyl cyanide

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

2-chloro-butyronitrile and 3-chloro-butyronitrile

2-chloro-butyronitrile and 3-chloro-butyronitrile

Conditions
ConditionsYield
With chlorine at 450℃;
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

sodium thiomethoxide
5188-07-8

sodium thiomethoxide

4-(methylthio)butyronitrile
59121-24-3

4-(methylthio)butyronitrile

Conditions
ConditionsYield
In ethanol at 20℃; for 25h; Inert atmosphere; Cooling with ice;100%
In ethanol
In ethanol at 25℃; for 15h;
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

tert-butyl N-(benzyloxy)carbamate
79722-21-7

tert-butyl N-(benzyloxy)carbamate

4-[N-(tert-butyloxycarbonyl)benzyloxyamino]butyronitrile
489452-95-1

4-[N-(tert-butyloxycarbonyl)benzyloxyamino]butyronitrile

Conditions
ConditionsYield
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere;
Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 80℃; for 6h;
100%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 70℃; for 18h; Inert atmosphere;
98%
With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 60 - 70℃; for 5h;80%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 0℃; Inert atmosphere;
Stage #2: 4-Chlorobutyronitrile In N,N-dimethyl-formamide at 85℃; Inert atmosphere;
70%
With sodium hydride; potassium iodide In N,N-dimethyl-formamide
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

(S)-(-)-[1-phenylethyl]-1H-imidazole
129696-60-2

(S)-(-)-[1-phenylethyl]-1H-imidazole

3-(3-cyanopropyl)-1-((1S)-1-phenylethyl)-1H-imidazol-3-ium chloride
1253119-37-7

3-(3-cyanopropyl)-1-((1S)-1-phenylethyl)-1H-imidazol-3-ium chloride

Conditions
ConditionsYield
In acetonitrile Reflux;100%
morpholine
110-91-8

morpholine

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

3-(morpholin-4-yl)-butanenitrile
5807-11-4

3-(morpholin-4-yl)-butanenitrile

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃; for 72h;99%
In toluene for 7h; Reflux;65%
at 20℃;63%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

cyclopropropanecarbonitrile
5500-21-0

cyclopropropanecarbonitrile

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; sodium chloride In water; dimethyl sulfoxide98%
With sodium hydride In ethylene glycol; mineral oil at 20 - 80℃; for 0.5h; Solvent; Reagent/catalyst;97.2%
With potassium tert-butylate In tetrahydrofuran at -30℃; for 0.333333h;89%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

methyl N-tosylanthranilate
50998-74-8

methyl N-tosylanthranilate

methyl 2-{(3-cyanopropyl)[(4-methylphenyl)sulfonyl]amino}benzoate
105895-93-0

methyl 2-{(3-cyanopropyl)[(4-methylphenyl)sulfonyl]amino}benzoate

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In butanone for 12h; Heating;98%
With potassium carbonate; potassium iodide In acetone for 168h; Heating;95%
With potassium carbonate; potassium iodide In butanone for 12h; Reflux;80.1%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

[1(R)-methyl-3-[(phenylmethyl)amino]propyl]carbamic acid, 1,1-dimethylethyl ester
170367-70-1

[1(R)-methyl-3-[(phenylmethyl)amino]propyl]carbamic acid, 1,1-dimethylethyl ester

3-[(3-cyanopropyl)(phenylmethyl)amino-1(R)-methylpropyl]carbamic acid, 1,1-dimethylethyl ester
170367-71-2

3-[(3-cyanopropyl)(phenylmethyl)amino-1(R)-methylpropyl]carbamic acid, 1,1-dimethylethyl ester

Conditions
ConditionsYield
With sodium carbonate; potassium iodide In butan-1-ol for 20h; Alkylation; Heating;98%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

N-(2,4,6-trimethylphenyl)imidazole
25364-44-7

N-(2,4,6-trimethylphenyl)imidazole

1-(2,4,6-trimethylphenyl)-3-(butylnitrile)imidazolium chloride
1247011-82-0

1-(2,4,6-trimethylphenyl)-3-(butylnitrile)imidazolium chloride

Conditions
ConditionsYield
In 1,2-dimethoxyethane for 72h; Reflux; Inert atmosphere;98%
In 1,2-dimethoxyethane Inert atmosphere; Heating;98%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

2-bromo-4-chlorobutyronitrile

2-bromo-4-chlorobutyronitrile

Conditions
ConditionsYield
With triphenyl phosphite; bromine at 80℃; for 4h; Reagent/catalyst;98%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

dimethylsilicon dichloride
75-78-5

dimethylsilicon dichloride

(3-cyanopropyl)dimethylsilyl chloride
18156-15-5

(3-cyanopropyl)dimethylsilyl chloride

Conditions
ConditionsYield
With magnesium; ethylene dibromide; manganese(ll) chloride In tetrahydrofuran at 65℃; for 2h; Inert atmosphere;96.1%
Stage #1: 4-Chlorobutyronitrile With sodium In toluene at 108 - 110℃; for 3h;
Stage #2: dimethylsilicon dichloride In toluene at 40 - 45℃; for 4h; Temperature;
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

1-(2-Methoxyphenyl)piperazine
35386-24-4

1-(2-Methoxyphenyl)piperazine

4‐[4‐(2‐methoxyphenyl)piperazin‐1‐yl]butannitrile
25024-99-1

4‐[4‐(2‐methoxyphenyl)piperazin‐1‐yl]butannitrile

Conditions
ConditionsYield
With cesium hydroxide; sodium iodide at 60℃; for 1.33333h; Microwave irradiation; Neat (no solvent); chemoselective reaction;96%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

N-p-toluenesulfonyl-4-chloro-anthranilic acid methyl ester
29247-79-8

N-p-toluenesulfonyl-4-chloro-anthranilic acid methyl ester

methyl 4-chloro-2-(N-tosyl-3-cyanopropylamino)benzoate
105896-01-3

methyl 4-chloro-2-(N-tosyl-3-cyanopropylamino)benzoate

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In acetone for 168h; Heating;95%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

N-[N-(tert-Butyloxycarbonyl)-3-aminopropyl]benzylamine
90914-08-2

N-[N-(tert-Butyloxycarbonyl)-3-aminopropyl]benzylamine

N-[N-(tert-Butoxycarbonyl)-3-aminopropyl]-N-(3-cyanopropyl)benzylamine
90914-11-7

N-[N-(tert-Butoxycarbonyl)-3-aminopropyl]-N-(3-cyanopropyl)benzylamine

Conditions
ConditionsYield
With sodium carbonate; potassium iodide In butan-1-ol for 48h; Heating;95%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

thiophenol
108-98-5

thiophenol

4-(phenylthio)butanenitrile
35756-39-9

4-(phenylthio)butanenitrile

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 48h; Inert atmosphere;95%
With triethylamine In N,N-dimethyl-formamide at 25℃;
With sodium methylate; sodium iodide 1.) methanol, 1 h, 2.) reflux, 12 h; Yield given. Multistep reaction;
salicylonitrile
611-20-1

salicylonitrile

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

4-(2-cyanophenoxy)butanenitrile

4-(2-cyanophenoxy)butanenitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 4h; Heating;95%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

1,2,3,4-tetrahydro-4-methylspiro
127934-39-8

1,2,3,4-tetrahydro-4-methylspiro

N-(γ-cyanopropyl)-3,4-dihydro-4-methylspiro[quinoline-2,1'-cyclohexane]
522592-78-5

N-(γ-cyanopropyl)-3,4-dihydro-4-methylspiro[quinoline-2,1'-cyclohexane]

Conditions
ConditionsYield
With sodium carbonate; potassium iodide In butan-1-ol Heating;95%
1-methyl-1H-imidazole
616-47-7

1-methyl-1H-imidazole

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

1-(3'-cyanopropyl)-3-methylimidazolium chloride

1-(3'-cyanopropyl)-3-methylimidazolium chloride

Conditions
ConditionsYield
at 80℃; for 24h;95%
at 70℃; for 48h; Neat (no solvent); Sealed vial;92%
at 80℃; for 24h;82%
Heating;78%
at 79.84℃; for 48h;
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

trans-hydridochloro-di-{1,2-bis(diphenylphosphino)ethane}iron(II)
19392-93-9, 32490-70-3

trans-hydridochloro-di-{1,2-bis(diphenylphosphino)ethane}iron(II)

trans-[FeH(4-chlorobutyronitrile)(dppe)2]Cl
252659-30-6

trans-[FeH(4-chlorobutyronitrile)(dppe)2]Cl

Conditions
ConditionsYield
In further solvent(s) Ar-atmosphere; stirring in ClCH2CH2CH2CN for 1 h; filtration, solvent removal (vac.), washing (Et2O); elem. anal.;95%
methanol
67-56-1

methanol

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

methyl 3-chloropropanimidate hydrochloride
77570-15-1

methyl 3-chloropropanimidate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether at 20℃; for 4h;94%
With hydrogenchloride In diethyl ether at -20℃; for 24h;90%
With hydrogenchloride In diethyl ether at 0℃; for 24h;70%
With hydrogenchloride In diethyl ether at -20 - 0℃; for 28h;
1-chloro-4,4-dihydroxy-4-butylamine

1-chloro-4,4-dihydroxy-4-butylamine

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With aluminum oxide; calcium hydroxide; 2-hydroxynitrobenzene In cyclohexane at 77 - 97℃; for 5.5h; Temperature; Reflux;92%
4-chlorobutyramide
2455-04-1

4-chlorobutyramide

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With formaldehyd; formic acid; acetonitrile for 12h; Heating;87%
2-((cyclobutylideneamino)oxy)-2-methylpropanoic acid

2-((cyclobutylideneamino)oxy)-2-methylpropanoic acid

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With N-chloro-succinimide; potassium acetate; 9-(2-mesityl)-10-methylacridinium perchlorate In acetonitrile at 20℃; for 1h; Irradiation; Sealed tube; Inert atmosphere;59%
5-chloro-valeric acid
1119-46-6

5-chloro-valeric acid

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With trifluoroacetic acid; trifluoroacetic anhydride; sodium nitrite at 20℃; nitrosative cleavage;57%
propyl cyanide
109-74-0

propyl cyanide

A

3-chlorobutyronitrile
53778-71-5

3-chlorobutyronitrile

B

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With chlorine Irradiation.mit UV-Licht;
With sodium persulfate; copper dichloride In water at 85 - 90℃; for 10h; Yield given. Yields of byproduct given;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;
hydroxymethyl propionamide
927-60-6

hydroxymethyl propionamide

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With thionyl chloride; benzene
With trichlorophosphate; benzene
With phosphorus trichloride
ethanol
64-17-5

ethanol

sodium cyanide
143-33-9

sodium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

4-bromobutanenitrile
5332-06-9

4-bromobutanenitrile

ethanol
64-17-5

ethanol

potassium cyanide
151-50-8

potassium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

Glutaronitrile
544-13-8

Glutaronitrile

sodium cyanide
143-33-9

sodium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

Glutaronitrile
544-13-8

Glutaronitrile

Conditions
ConditionsYield
With methanol
potassium cyanide
151-50-8

potassium cyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With ethanol
With ethanol; water Alkohol abdestillieren,Wasser zum Rueckstand geben,abgeschiedene Oelschicht abheben und fraktionieren;
1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

4-butanolide
96-48-0

4-butanolide

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
(i) liq. NH3, (ii) SOCl2; Multistep reaction;
tetraethylammoniumcyanide
13435-20-6

tetraethylammoniumcyanide

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
In dichloromethane
2,4-dichlorobutanenitrile
77100-86-8

2,4-dichlorobutanenitrile

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
With acetic acid; zinc for 2h; Yield given;
1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

alcoholic KCN

alcoholic KCN

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

propyl cyanide
109-74-0

propyl cyanide

chlorine
7782-50-5

chlorine

A

3-chlorobutyronitrile
53778-71-5

3-chlorobutyronitrile

B

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

Conditions
ConditionsYield
mit UV-Licht in der Dampfphase.Irradiation;
propyl cyanide
109-74-0

propyl cyanide

chlorine
7782-50-5

chlorine

A

3-chlorobutyronitrile
53778-71-5

3-chlorobutyronitrile

B

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

C

2-chlorobutyronitrile
4158-37-6

2-chlorobutyronitrile

Conditions
ConditionsYield
at 450℃; Dampfphase;
propyl cyanide
109-74-0

propyl cyanide

A

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

B

2-chloro-butyronitrile and 3-chloro-butyronitrile

2-chloro-butyronitrile and 3-chloro-butyronitrile

Conditions
ConditionsYield
With chlorine at 450℃;
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

sodium thiomethoxide
5188-07-8

sodium thiomethoxide

4-(methylthio)butyronitrile
59121-24-3

4-(methylthio)butyronitrile

Conditions
ConditionsYield
In ethanol at 20℃; for 25h; Inert atmosphere; Cooling with ice;100%
In ethanol
In ethanol at 25℃; for 15h;
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

tert-butyl N-(benzyloxy)carbamate
79722-21-7

tert-butyl N-(benzyloxy)carbamate

4-[N-(tert-butyloxycarbonyl)benzyloxyamino]butyronitrile
489452-95-1

4-[N-(tert-butyloxycarbonyl)benzyloxyamino]butyronitrile

Conditions
ConditionsYield
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere;
Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 80℃; for 6h;
100%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 4-Chlorobutyronitrile With sodium iodide In N,N-dimethyl-formamide at 70℃; for 18h; Inert atmosphere;
98%
With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 60 - 70℃; for 5h;80%
Stage #1: tert-butyl N-(benzyloxy)carbamate With sodium hydride; sodium iodide In N,N-dimethyl-formamide at 0℃; Inert atmosphere;
Stage #2: 4-Chlorobutyronitrile In N,N-dimethyl-formamide at 85℃; Inert atmosphere;
70%
With sodium hydride; potassium iodide In N,N-dimethyl-formamide
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

(S)-(-)-[1-phenylethyl]-1H-imidazole
129696-60-2

(S)-(-)-[1-phenylethyl]-1H-imidazole

3-(3-cyanopropyl)-1-((1S)-1-phenylethyl)-1H-imidazol-3-ium chloride
1253119-37-7

3-(3-cyanopropyl)-1-((1S)-1-phenylethyl)-1H-imidazol-3-ium chloride

Conditions
ConditionsYield
In acetonitrile Reflux;100%
morpholine
110-91-8

morpholine

4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

3-(morpholin-4-yl)-butanenitrile
5807-11-4

3-(morpholin-4-yl)-butanenitrile

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃; for 72h;99%
In toluene for 7h; Reflux;65%
at 20℃;63%
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

cyclopropropanecarbonitrile
5500-21-0

cyclopropropanecarbonitrile

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; sodium chloride In water; dimethyl sulfoxide98%
With sodium hydride In ethylene glycol; mineral oil at 20 - 80℃; for 0.5h; Solvent; Reagent/catalyst;97.2%
With potassium tert-butylate In tetrahydrofuran at -30℃; for 0.333333h;89%

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