CAS No.96-48-0,gamma-Butyrolactone Suppliers

: 6117-80-2
1,4-butenediol

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With 5 wt% Pd nanoparticles loaded on phosphate anion exchanged [Mg6Al2(OH)16]CO3*xH2O; air at 50℃; under 760.051 Torr; for 6h; Reagent/catalyst; Irradiation;	100%
With acetone; dihydridotetrakis(triphenylphosphine)ruthenium In toluene at 180℃; for 3h;	88 % Chromat.

: 3128-06-1
5-ketohexanoic acid

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With 5% active carbon-supported ruthenium; isopropyl alcohol at 160℃; for 0.416667h; Reagent/catalyst; Temperature; Microwave irradiation;	100%
With hydrogen In 1,4-dioxane at 180℃; under 37503.8 Torr; for 3h; Reagent/catalyst; Solvent; Autoclave;

: 98-01-1
furfural

: 110-63-4
Butane-1,4-diol

A: 534-22-5
2-methylfuran

B: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With hydrogen; Cu-based catalyst at 210℃; Product distribution; Further Variations:; Temperatures; reaction in vapour phase, fixed bed reactor, coupled dehydrogenation reactions of title comp. and INO 160;	A 96.5% B 99.4%

...Expand

: 1191-95-3
cyclobutanone

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With oxone; silica gel In dichloromethane at 20℃; for 1h; Baeyer-Villiger oxidation;	99%
With acyltransferase from Mycobacterium smegmatis; dihydrogen peroxide; ethyl acetate In water at 35℃; for 2h; Baeyer-Villiger Ketone Oxidation; Enzymatic reaction;	99%
With 2,2,2-trifluoroethanol; dihydrogen peroxide for 24h; Ambient temperature;	98%

: 925-57-5
methyl 4-hydroxybutanoate

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With C16H25N3O2S In n-heptane for 3h; Reflux; Molecular sieve; Inert atmosphere;	99%
With C16H25N3O2S In n-heptane for 48h; Reflux; Molecular sieve;	99%
In hexane at 26℃; porcine pancreatic lipase (PPL);
With porcine pancreatic lipase (E.(1)C313) In diethyl ether at 26℃; Yield given;

: 497-23-4
2-buten-4-olide

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With hydrogen In methanol under 26252.6 Torr; for 2h; Reagent/catalyst; Autoclave;	99%
With 0.5% palladium on silica gel; hydrogen In methanol at 80℃; under 26252.6 Torr; Catalytic behavior; Kinetics; Reagent/catalyst; Autoclave;	92.6%
With Ni#NiO; hydrogen In ethanol at 80℃; under 22502.3 Torr; for 1h; Reagent/catalyst; Autoclave;	86.6%

: 110-16-7
maleic acid

A: 109-99-9
tetrahydrofuran

B: 96-48-0
4-butanolide

C: 110-63-4
Butane-1,4-diol

D: 110-15-6
succinic acid

E: 64-19-7
acetic acid

Conditions

Conditions	Yield
With hydrogen; 0.5 percent Pd on Rutile TiO2 at 110℃; Product distribution / selectivity;	A 0.37% B 0.28% C 0.37% D 98.89% E 0.08%

...Expand

: 110-63-4
Butane-1,4-diol

A: 96-48-0
4-butanolide

B: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen; Cu-based catalyst at 190℃; Product distribution; Further Variations:; Temperatures; reaction in vapour phase, fixed bed reactor;	A 98.8% B 0.8%

: 110-16-7
maleic acid

A: 109-99-9
tetrahydrofuran

B: 96-48-0
4-butanolide

C: 67-56-1
methanol

D: 110-63-4
Butane-1,4-diol

E: 617-48-1
malic acid

F: 110-15-6
succinic acid

G: 64-19-7
acetic acid

H: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen; 0.5percent Pd on Rutile TiO2 at 110℃; Product distribution / selectivity;	A 0.45% B 0.06% C 0% D 0.21% E 0.36% F 98.73% G 0.04% H 0.08%

...Expand

: 110-16-7
maleic acid

A: 109-99-9
tetrahydrofuran

B: 96-48-0
4-butanolide

C: 110-63-4
Butane-1,4-diol

D: 591-81-1
4-hydroxybutanoic acid

E: 110-15-6
succinic acid

F: 64-19-7
acetic acid

G: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen; 0.5percent Pd on Rutile TiO2 at 110℃; Product distribution / selectivity;	A 0.77% B 0.38% C 0.24% D 0.05% E 98.28% F 0.02% G 0.26%

...Expand

: 109-99-9
tetrahydrofuran

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With trans-{dioxoruthenium(VI)(N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)propylenediamine)}(perchlorate)2 In acetonitrile at 25℃; for 1h;	98%
Stage #1: tetrahydrofuran With bromine In dichloromethane; water for 1h; Reflux; Stage #2: With dihydrogen peroxide In dichloromethane; water for 1h; Reflux;	98%
With manganese (VII)-oxide In tetrachloromethane; acetone at -45℃;	86%

: 110-63-4
Butane-1,4-diol

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With phosphoric acid tributyl ester at 119.84℃; under 9375.94 Torr; for 8h; Catalytic behavior; Reagent/catalyst; Autoclave;	98%
With Cu-Al hydrotalcite In 1,4-dioxane at 220℃; under 12001.2 Torr; for 0.045h;	98%
With Hoveyda-Grubbs catalyst second generation; potassium hydroxide; tricyclohexylphosphine In toluene at 110℃; for 24h; Reagent/catalyst; Schlenk technique; Inert atmosphere;	98%

: 624-48-6
dimethyl cis-but-2-ene-1,4-dioate

A: 109-99-9
tetrahydrofuran

B: 13436-45-8
2-methoxytetrahydrofuran

C: 96-48-0
4-butanolide

D: 71-23-8
propan-1-ol

E: 64001-06-5
2-(4'-hydroxybutoxy)-tetrahydrofuran

F: 110-63-4
Butane-1,4-diol

G: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen; copper catalyst, T 4489, Sud-Chemie AG, Munich at 150 - 280℃; under 187519 Torr; Neat liquid(s) and gas(es)/vapour(s);	A 1% B n/a C 0.4% D n/a E n/a F 98% G 0.5%

...Expand

: 36603-83-5
5-Chloro-dihydro-2(3H)-furanone

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With palladium on activated carbon; hydrogen at 200℃; under 760.051 Torr; for 149h; Temperature; Reagent/catalyst;	97.98%

: 160194-31-0
4-(tert-butyldimethylsilyl)but-3-yn-1-ol

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With 8-isopropyl-quinoline-N-oxide; [Au(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(NTf2)] In fluorobenzene; 1,2-dichloro-ethane at 60℃; for 5h;	96%

: 108-31-6
maleic anhydride

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 159.84℃; under 37503.8 Torr; Reagent/catalyst; Autoclave;	95.94%
at 275℃; under 51485.6 Torr; Hydrogenation.an einen Nickel-Chrom-Molybdaen-Katalysator;
With cobalt at 200℃; under 102971 Torr; Hydrogenation;

: 5061-21-2
α-bromo-γ-butyrolactone

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With DMBI In tetrahydrofuran for 4h; Heating;	95%
With nickel In tetrahydrofuran at 20℃; for 0.75h;	95%
With triethyl borane; tri-n-butyl-tin hydride In hexane; toluene at -78℃; for 0.5h;	90%

: 110-15-6
succinic acid

A: 96-48-0
4-butanolide

B: 110-63-4
Butane-1,4-diol

Conditions

Conditions	Yield
With C36H54IrN2P2(1+)*C24H20B(1-); hydrogen; sodium hydride In toluene at 180℃; under 7500.75 - 45004.5 Torr; for 18h; Reagent/catalyst; Temperature; Pressure; Autoclave; Sealed tube;	A 5% B 95%
Stage #1: succinic acid In 1,4-dioxane at 500℃; for 4h; Stage #2: With hydrogen In 1,4-dioxane at 200℃; under 60006 Torr; for 5h; Catalytic behavior; Reagent/catalyst;	A n/a B 64.7%
With hydrogen In water at 130℃; under 37503.8 Torr; for 12h; Pressure; Reagent/catalyst; Temperature; Autoclave;	A 34% B 23%

: 13325-10-5
4-Aminobutanol

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With hydrogenchloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; laccase from Trametes versicolor In water for 15h; pH=5.5; Enzymatic reaction; chemoselective reaction;	95%

: 3879-08-1
4-hydroxybutanoic acid hydrazide

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With benzeneseleninic acid In dichloromethane for 1.75h;	91%

: 110-63-4
Butane-1,4-diol

: 1099-45-2
ethyl (triphenylphosphoranylidene)acetate

A: 1092929-40-2
(Z)-6-hydroxy-hex-2-enoic acid ethyl ester

B: 96-48-0
4-butanolide

C: 15898-58-5
octa-2,6-dienedioic acid diethyl ester

D: 13038-15-8
(E)-6-hydroxy-hex-2-enoic acid ethyl ester

Conditions

Conditions	Yield
With manganese(IV) oxide In dichloromethane at 20℃; for 48h; Wittig olefination;	A 5% B n/a C n/a D 91%

...Expand

: 110-16-7
maleic acid

A: 109-99-9
tetrahydrofuran

B: 96-48-0
4-butanolide

C: 110-63-4
Butane-1,4-diol

D: 591-81-1
4-hydroxybutanoic acid

E: 617-48-1
malic acid

F: 110-15-6
succinic acid

G: 64-19-7
acetic acid

Conditions

Conditions	Yield
With hydrogen; 0.5percent Pd/2.0percent Re on Rutile TiO2 at 110℃; Product distribution / selectivity;	A 1.27% B 4.78% C 1.55% D 1.24% E 0.48% F 90.6% G 0.08%

...Expand

: 108-30-5
succinic acid anhydride

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 199.84℃; under 37503.8 Torr; for 5h; Catalytic behavior; Activation energy; Temperature;	90.1%
With lithium borohydride In tetrahydrofuran for 0.25h;	68%
With lithium borohydride In tetrahydrofuran at 25℃; for 0.25h; Mechanism; other cyclic anhydrides;	68%

: 591-81-1
4-hydroxybutanoic acid

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With sulfuric acid In chloroform at 60℃; for 1h; pH=0.5; pH-value; Solvent; Temperature;	90%
bei der Destillation;
With hydrogenchloride In ethanol at 25℃; Rate constant;
With cis-nitrous acid at 25℃; Rate constant;
With hydrogenchloride at 35℃; Equilibrium constant; Further Variations:; Temperatures;

: 110-15-6
succinic acid

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With 5% active carbon-supported ruthenium; hydrogen at 150℃; under 26252.6 Torr;	90%
With butanediamide; hydrogen In Triethylene glycol dimethyl ether at 205℃; under 6750.68 Torr; for 2h; Reagent/catalyst; Autoclave;	30%
With D-glucose; hydrogen In Triethylene glycol dimethyl ether at 205℃; under 6750.68 Torr; for 2h; Autoclave;	27.5%

: 821-11-4, 6117-80-2, 110-64-5
1,4-butenediol

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With [RuCl2(PPh3)2(2-PyCH21,3,5-triaza-7-phosphadamantane)].Br; potassium hydroxide In water for 48h; Reagent/catalyst; Schlenk technique; Reflux; Inert atmosphere; Green chemistry;	90%
With potassium hydroxide; tricyclohexylphosphine In toluene at 110℃; for 24h; Schlenk technique;

: 108-31-6
maleic anhydride

A: 96-48-0
4-butanolide

B: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 159.84℃; under 37503.8 Torr; Reagent/catalyst; Autoclave;	A 89.9% B 6.83%

: 628-22-8
4-hydroxy-1-butanitrile

: 96-48-0
4-butanolide

Conditions

Conditions	Yield
With ; water In 1,2-dimethoxyethane at 140℃; for 24h;	89%

: 110-15-6
succinic acid

A: 109-99-9
tetrahydrofuran

B: 96-48-0
4-butanolide

C: 110-63-4
Butane-1,4-diol

D: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 139.84℃; under 60006 Torr; for 96h; Catalytic behavior; Reagent/catalyst; Time; Temperature; Autoclave; Overall yield = 100 %;	A 0.2% B 3.1% C 89% D 7.6%
With hydrogen; 1.0percent Pd/ 3.0percent Re on Rutile TiO2 at 164 - 185℃; for 21 - 237h; Product distribution / selectivity;	A 2.95% B 0% C 81.5% D 3.35%
With hydrogen; 0percent Pd/5.0percent Re on Rutile TiO2 at 170 - 185℃; for 90 - 825h; Product distribution / selectivity;	A 3.38% B 0% C 64.14% D 2.86%

...Expand

: 4-{[(1Z,3E)-2-(2-furylcarbonyl)-5-oxo-1,5-diphenylpenta-1,3-dienyl]amino}butanoic acid

A: 96-48-0
4-butanolide

B: 3-(2-furylcarbonyl)-2,6-diphenylpyridine

Conditions

Conditions	Yield
In ethanol at 78℃; for 4h;	A n/a B 89%

: 96-48-0
4-butanolide

: 100-46-9
benzylamine

: 19340-88-6
N-benzyl-4-hydroxybutanamide

Conditions

Conditions	Yield
With bis(trifluoromethane)sulfonimide lithium In chloroform at 85℃; for 40h;	100%
Stage #1: benzylamine With diisobutylaluminium hydride In tetrahydrofuran; toluene Stage #2: 4-butanolide In tetrahydrofuran at 20℃; for 0.5h;	98%
In benzene for 12h; Reflux;	98%

: 123-75-1
pyrrolidine

: 96-48-0
4-butanolide

: 73200-24-5
4-hydroxy-1-(pyrrolidin-1-yl)butan-1-one

Conditions

Conditions	Yield
With triethylamine Inert atmosphere; Reflux;	100%
With triethylamine for 16h; Reflux;	94%
In benzene for 3h; Heating;	90%

: 110-89-4
piperidine

: 96-48-0
4-butanolide

: 86452-60-0
4-hydroxy-1-(piperidin-1-yl)butan-1-one

Conditions

Conditions	Yield
With bis(trifluoromethane)sulfonimide lithium In chloroform at 85℃; for 40h;	100%
In acetonitrile at 30℃; under 6750540 Torr; for 96h;	99%
In acetonitrile at 30℃; under 6750540 Torr; for 168h;	99%

: 96-48-0
4-butanolide

: 117968-50-0
(2S,5S)-2,5-dimethylpyrrolidine

: 139108-39-7
(2S,5S)-1-(4-hydroxybutanoyl)-2,5-dimethylpyrrolidine

Conditions

Conditions	Yield
With triethylamine for 12h; Heating;	100%
With triethylamine for 48h; Heating;	96%

: 96-48-0
4-butanolide

: 109-89-7
diethylamine

: 86452-59-7
N,N-Diethyl-4-hydroxy-butyramide

Conditions

Conditions	Yield
In acetonitrile at 30℃; under 6750540 Torr; for 96h;	100%
Stage #1: diethylamine With diisobutylaluminium hydride In tetrahydrofuran; toluene Stage #2: 4-butanolide In tetrahydrofuran at 45℃; for 2h;	72%

: 96-48-0
4-butanolide

: 109-94-4
formic acid ethyl ester

: 51270-64-5, 54211-97-1, 93698-26-1
sodium salt of (Z)-3-(hydroxymethylene)dihydro-2(3H)-furanone

Conditions

Conditions	Yield
With sodium hydride	100%
With sodium In diethyl ether at -20 - -15℃; for 5h;

: 96-48-0
4-butanolide

: 109-94-4
formic acid ethyl ester

: 54211-97-1
sodium salt of (E)-3-(hydroxymethylene)dihydro-2(3H)-furanone

Conditions

Conditions	Yield
With sodium hydride	100%
With ethanol; sodium hydride In 1,2-dimethoxyethane at 40℃; for 22h; cross-Claisen acylation;	97%
With sodium methylate In diethyl ether for 12h;	69%
With sodium hydroxide In 1,2-dimethoxyethane at 60℃; for 16h;	66%

: 96-48-0
4-butanolide

: 110-63-4
Butane-1,4-diol

Conditions

Conditions	Yield
With sodium aluminum tetrahydride In tetrahydrofuran at 0℃; for 0.0833333h;	100%
With C31H33ClN2O3RuS; potassium tert-butylate; hydrogen In isopropyl alcohol at 60℃; under 37503.8 Torr; for 48h; Inert atmosphere;	100%
With C39H39N6ORu(1+)*Br(1-); potassium methanolate; hydrogen In tetrahydrofuran at 100℃; under 37503.8 Torr; for 16h; Reagent/catalyst;	100%

: 96-48-0
4-butanolide

: 67764-03-8
4-iodobutanoate de trimethylsilyle

Conditions

Conditions	Yield
With trimethylsilyl iodide; iodine In chloroform-d1 for 1h; Ambient temperature;	100%

: 96-48-0
4-butanolide

: 502-85-2
sodium 4-hydroxybutanoate

Conditions

Conditions	Yield
With water; sodium hydroxide at 20℃; Inert atmosphere;	100%
With ethanol; sodium hydroxide at 20℃; for 2h;	95%
With sodium hydroxide at 45 - 60℃; for 12h;	95%

: 96-48-0
4-butanolide

: 127421-48-1
iodosilyl 4-iodobutyrate

Conditions

Conditions	Yield
With diiodosilane; iodine In chloroform-d1 at 50℃; for 0.166667h;	100%

: 96-48-0
4-butanolide

: 75-04-7
ethylamine

: 42042-64-8
N-ethyl-4-hydroxybutanamide

Conditions

Conditions	Yield
In tetrahydrofuran at 50℃; for 22h;	100%
In tetrahydrofuran at 20℃; Acylation;
With ammonia In methanol at 20℃;

: 96-48-0
4-butanolide

: 13325-10-5
4-Aminobutanol

: 4-hydroxy-N-(4-hydroxybutyl)butanamide

Conditions

Conditions	Yield
In 5,5-dimethyl-1,3-cyclohexadiene Reflux;	100%
In various solvent(s) for 18h; Heating;

: 96-48-0
4-butanolide

: 63255-29-8
Lithium γ-hydroxybutyrate

Conditions

Conditions	Yield
With lithium hydroxide monohydrate In methanol; water at 20℃; for 16h;	100%
With lithium hydroxide In methanol; water at 20℃; for 16h;	100%
With lithium hydroxide; water In methanol at 20℃;

: 96-48-0
4-butanolide

: 100-58-3
phenylmagnesium bromide

: 1023-94-5
1,1-diphenylbutan-1,4-diol

Conditions

Conditions	Yield
With hydrogenchloride; ammonium chloride In tetrahydrofuran	100%
Stage #1: 4-butanolide; phenylmagnesium bromide In tetrahydrofuran; diethyl ether at -78 - 20℃; Inert atmosphere; Stage #2: With water; ammonium chloride In tetrahydrofuran; diethyl ether at 10℃; Cooling with ice;
In tetrahydrofuran Grignard reaction; Reflux;

: 96-48-0
4-butanolide

: 591-19-5
3-bromoaniline

: 38348-83-3
1-(3-bromophenyl)-2-pyrrolidinone

Conditions

Conditions	Yield
With hydrogenchloride In water at 160℃; for 36h;	100%

: 96-48-0
4-butanolide

: 15570-12-4
3-methoxybenzenethiol

: 4-((3-methoxyphenyl)thio)butanoic acid sodium salt

Conditions

Conditions	Yield
With ethanol; sodium for 24h; Inert atmosphere; Reflux;	100%
With sodium In ethanol for 24h; Inert atmosphere; Reflux;	100%

: 96-48-0
4-butanolide

: 74-89-5
methylamine

: 872-50-4
1-methyl-pyrrolidin-2-one

Conditions

Conditions	Yield
With water; ZSM-5 at 280℃;	99%
In water at 300℃; under 75007.5 Torr; Concentration;	99.9%
at 255℃; under 15001.5 Torr; for 3h;	98.2%

: 96-48-0
4-butanolide

: 74-89-5
methylamine

: 37941-69-8
γ-hydroxybutyric acid monomethylamide

Conditions

Conditions	Yield
at 20℃; for 1.5h;	99%
	99.5%
With water at 0 - 5℃; for 2h;	95.5%

: 96-48-0
4-butanolide

: 124-40-3
dimethyl amine

: 37941-69-8
γ-hydroxybutyric acid monomethylamide

Conditions

Conditions	Yield
	99.5%

: 96-48-0
4-butanolide

: 109-73-9
N-butylamine

: 42042-67-1
N-butyl-4-hydroxybutyramide

Conditions

Conditions	Yield
With bis(trifluoromethane)sulfonimide lithium In chloroform at 85℃; for 40h;	99%

: 96-48-0
4-butanolide

: 95-92-1
oxalic acid diethyl ester

: 42564-36-3
oxo-(2-oxotetrahydrofuran-3-yl)acetic acid ethyl ester

Conditions

Conditions	Yield
With sodium ethanolate In ethanol at 0 - 20℃; for 6.25h;	99%
With sodium ethanolate In ethanol at 0 - 20℃;	96%
With sodium methylate	72%

: 96-48-0
4-butanolide

: 100-46-9
benzylamine

: 5291-77-0
1-benzyl-2-pyrrolidone

Conditions

Conditions	Yield
With 1-butyl-3-methylimidazolium Tetrafluoroborate In 1,4-dioxane at 220℃; for 0.583333h; Microwave irradiation;	99%
for 24h; Heating;	79%
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium acetate In toluene at 110℃; for 36h; Reagent/catalyst; Inert atmosphere; Glovebox; Molecular sieve; Schlenk technique;	65%

: 96-48-0
4-butanolide

: 507-63-1
1-iodoheptadecafluorooctane

: 112678-33-8
2-Heptadecafluorooctyl-tetrahydro-furan-2-ol

Conditions

Conditions	Yield
With methyllithium; lithium bromide In diethyl ether at -78℃; for 1h;	99%
With methyllithium In diethyl ether at -78℃; for 1h;	99%

: 96-48-0
4-butanolide

: 107-11-9
1-amino-2-propene

: 98435-58-6
N-allyl 4-hydroxybutyramide

Conditions

Conditions	Yield
at 120 - 130℃; for 3h;	99%
at 120 - 130℃; for 3h;	99%
With bis(trifluoromethane)sulfonimide lithium In chloroform at 85℃; for 40h;	99%
In benzene for 12h; Inert atmosphere; Reflux;

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