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SJZ THLD IMP & EXP CO LTD

Product Name : Amantadine Hcl CAS NO: 665-66-7 MF: C10H15NH2.HCL Molecular weight: 187.71 Appearance: White crystalline powder Content: 99% Usage Of Amantadine Hcl 1) As Anti-virus medicine Used to make intermediate of anti-virus medicine

High quality amantadine hydrochloride pharma grade /feed grade

Cas:665-66-7

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

1-Adamantanamine Hydrochloride

Cas:665-66-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

SICHUAN ZHONGBANG with its subsidiaries LUZHOU FUBANG& LUZHOU DAZHOU are specializing in the research, development, manufacturing and trade of fine chemicals, pesticide intermediates and pharmaceutical intermediates.

1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:0 Metric Ton

FOB Price: $18.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-Adamantanamine hydrochloride Manufacturer/High quality/Best price/In stock

Cas:665-66-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White crystals or crystalliine powder Complies Identification In

High purity Various Specifications 1-Adamantanamine hydrochloride CAS:665-66-7

Cas:665-66-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Adamantanamine hydrochloride CAS 665-66-7 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals i

Adamantanamine hydrochloride CAS 665-66-7

Cas:665-66-7

Min.Order:25 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Located in Zhengdong New District, Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is comprehensive high-tech modern enterprises integrating professional R&D, production and sales. Strong technical force, with a long

1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Amantadine hydrochloride

Cas:665-66-7

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 1-Adamantanamine hydrochloride 665-66-7 ISO Producer

Cas:665-66-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-Adamantylamine hydrochloride

Cas:665-66-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

amantadine hydrochloride

Cas:665-66-7

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Hubei DiBo chemical co., LTD

Name:1-Adamantanamine hydrochloride CAS NO:665-66-7 Grade:Medical scientific research and export Molecular formula:C10H17N Molecular weight:151.2487 Product Quality 12 years of chemical raw materials Mature operation of the industry Syst

1-Adamantanamine hydrochloride/ CAS:665-66-7/ raw material/ high-quality

Cas:665-66-7

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--665-66-7--2-Bromoacetophenone in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business relation

TIANFUCHEM--665-66-7--2-Bromoacetophenone in stock

Cas:665-66-7

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Hebei Nengqian Chemical Import and Export Co., LTD.. is located in xingtai City, Hebei Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutica

High purity CAS 665-66-7 1-Adamantanamine hydrochloride in stock

Cas:665-66-7

Min.Order:1 Gram

FOB Price: $12.0 / 15.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 665-66-7 with best quality

Cas:665-66-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Chemical Name: Amantadine Hydrochloride Synonyms: 1-Adamantanamine hydrochloride; Amantadine HCl CAS No.: 665-66-7 Molecular Formula: C10H15NH2HCl Purity: 98.0-102.0% Properties: white crystal powder, odourless; soluble in water, ethano

Pharmaceutical grade raw material 99% Amantadine Hcl for API

Cas:665-66-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White Crystalline solid Storage:Room temperature Package:25kg/drum Application:Antiviral API Transportation:Express/Sea/Air Port:Any port in china

1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 665-66-7 1-Adamantanamine hydrochloride with best price

Cas:665-66-7

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Adamantanamine hydrochloride 665-66-7

Cas:665-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:1 Kilogram

FOB Price: $30.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

1-Adamantanamine hydrochloride CAS: 665-66-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality org

1-Adamantanamine hydrochloride CAS: 665-66-7

Cas:665-66-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Adamantanamine HCL

Cas:665-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

1-Adamantanamine hydrochloride .665-66-7

Cas:665-66-7

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

china manufacture/Amantadine Hcl 665-66-7/amantadine in antiviral drugs

Cas:665-66-7

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:665-66-7

Cas:665-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

1-Adamantanamine hydrochloride CAS: 665-66-7 Specification mp >300 °c(lit.) storage temp. -20°c freezer solubility h2o: 50 mg/ml water solubility soluble sensitive hygroscopic

Factory supply 1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

1-Adamantanamine hydrochloride

Cas:665-66-7

Min.Order:1 Kilogram

FOB Price: $70.0 / 90.0

Type:Lab/Research institutions

inquiry

Synthetic route

1-Adamantanamine
768-94-5

1-Adamantanamine

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
With hydroxylamine hydrochloride In ethanol for 2h; Reflux;100%
With hydrogenchloride In water; toluene at 0 - 20℃; for 1h; Product distribution / selectivity;
With hydrogenchloride In diethyl ether
1-Azidoadamantane
24886-73-5

1-Azidoadamantane

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
With propan-1-ol; 2,2'-azobis(isobutyronitrile); phenylsilane; bis(tri-n-butyltin)oxide In benzene Reduction; Heating;99%
2,2,2-trichloroethyl (adamantan-1-yl)carbamate
17341-91-2

2,2,2-trichloroethyl (adamantan-1-yl)carbamate

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Stage #1: 2,2,2-trichloroethyl 1-adamantylcarbamate With acetic acid; zinc
Stage #2: With acetyl chloride In methanol Heating;
99%
N-(1-adamantyl)acetamide
880-52-4

N-(1-adamantyl)acetamide

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Stage #1: N-(1-adamantyl)acetamide With sodium heptadecanoic acid; β‐cyclodextrin; sodium hydroxide In ethanol; water for 20h; Reflux;
Stage #2: With hydrogenchloride In water at 70℃;
96.5%
Stage #1: N-(1-adamantyl)acetamide With propylene glycol; potassium hydroxide In water at 125 - 130℃; for 8h; Green chemistry;
Stage #2: With hydrogenchloride In dichloromethane; water at 55 - 60℃; for 1h; Temperature; Time; Green chemistry;
82%
Stage #1: N-(1-adamantyl)acetamide With methanol; water; sodium hydroxide at 145℃; for 8h; Autoclave;
Stage #2: With hydrogenchloride In dichloromethane; water at 50℃; for 0.5h; Autoclave;
82.2%
N-(1-adamantyl)formamide
3405-48-9

N-(1-adamantyl)formamide

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 85 - 90℃; for 1h;93%
1-nitroadamantane
7575-82-8

1-nitroadamantane

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Stage #1: 1-nitroadamantane With iron(III) chloride hexahydrate; hydrazine hydrate In diethyl ether; ethanol at 40℃; Inert atmosphere;
Stage #2: With hydrogenchloride In water at 70℃; for 0.5h;
89.5%
Stage #1: 1-nitroadamantane With C36H56Cl3CrN2O; magnesium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In tetrahydrofuran at 60℃; for 24h; Inert atmosphere; Schlenk technique;
Stage #2: With hydrogenchloride In tetrahydrofuran; water; ethyl acetate at 20℃;
83%
adamantylmagnesium bromide
57680-77-0

adamantylmagnesium bromide

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Stage #1: adamantylmagnesium bromide With N,N,N,N,N,N-hexamethylphosphoric triamide; copper(I) cyanide*lithium chloride; 4,4'-bis(4-trifluoromethyl)benzophenone O-methylsulfonyloxime In tetrahydrofuran at 0℃; for 1h; Substitution;
Stage #2: With hydrogenchloride In water; acetone at 25℃; for 0.5h; Hydrolysis;
82%
Multi-step reaction with 2 steps
1: chlorobenzene; diethyl ether / 0.5 h / 0 °C
2: 334 mg / aq. HCl / ethanol / 10 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: CuCN*2LiCl / tetrahydrofuran; hexamethylphosphoric acid triamide / 0.5 h / 0 °C
2: aq. HCl
View Scheme
1-Adamantyl bromide
768-90-1

1-Adamantyl bromide

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Stage #1: 1-Adamantyl bromide With urea at 180 - 240℃;
Stage #2: With hydrogenchloride In water Temperature;
49.7%
1-(Chloroamino)adamantane
24375-06-2

1-(Chloroamino)adamantane

A

N,N-dichloro-adamantan-1-amine
24375-05-1

N,N-dichloro-adamantan-1-amine

B

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
silica gel In methanol; dichloromethane disproportionation; Yields of byproduct given;
Adamantan-1-yl-[bis-(4-trifluoromethyl-phenyl)-methylene]-amine

Adamantan-1-yl-[bis-(4-trifluoromethyl-phenyl)-methylene]-amine

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride Yield given;
adamantan-1-yl-(4,4,5,5-tetramethyl-[1,3]dioxolan-2-ylidene)-amine

adamantan-1-yl-(4,4,5,5-tetramethyl-[1,3]dioxolan-2-ylidene)-amine

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol for 10h; Heating;334 mg
adamantane
281-23-2

adamantane

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: nitric acid / 0.5 h / 25 - 30 °C
2: acetic acid / 0.5 h / 125 °C
3: acetic acid; nitric acid / water / 125 °C
4: sodium hydroxide / water
5: hydrogenchloride / diethyl ether
View Scheme
Multi-step reaction with 2 steps
1.1: Nitrogen dioxide; ozone / 0.5 h / -78 - 30 °C
2.1: iron(III) chloride hexahydrate; hydrazine hydrate / ethanol; diethyl ether / 40 °C / Inert atmosphere
2.2: 0.5 h / 70 °C
View Scheme
1-nitroxyadamantane
32314-61-7

1-nitroxyadamantane

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: acetic acid / 0.5 h / 125 °C
2: acetic acid; nitric acid / water / 125 °C
3: sodium hydroxide / water
4: hydrogenchloride / diethyl ether
View Scheme
1-(carbamoylamino)adamantne
13072-69-0

1-(carbamoylamino)adamantne

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid; nitric acid / water / 125 °C
2: sodium hydroxide / water
3: hydrogenchloride / diethyl ether
View Scheme
With hydrogenchloride; pyrographite In water at 70℃; for 1h; pH=3 - 4; Industrial scale;6.4 kg
adamantan-1-amine hydronitrate

adamantan-1-amine hydronitrate

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / water
2: hydrogenchloride / diethyl ether
View Scheme
1-acetyladamantane
1660-04-4

1-acetyladamantane

amantadine hydrochloride
665-66-7

amantadine hydrochloride

Conditions
ConditionsYield
Stage #1: 1-acetyladamantane With tetrabutylammomium bromide; sodium hydroxide In water; ethylene glycol at 40 - 190℃; for 12h; Autoclave;
Stage #2: With hydrogenchloride In water; ethylene glycol pH=4;
adamantane
281-23-2

adamantane

A

amantadine hydrochloride
665-66-7

amantadine hydrochloride

B

adamantan-2-amine hydrochloride
10523-68-9

adamantan-2-amine hydrochloride

Conditions
ConditionsYield
Stage #1: adamantane With methanol; cerium(III) chloride; di-tert-butyl-diazodicarboxylate; tetrabutyl-ammonium chloride In acetonitrile at 20℃; for 10h; Irradiation; Inert atmosphere; Sealed tube;
Stage #2: With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Reagent/catalyst; Further stages;
Trimethyl orthoacetate
1445-45-0

Trimethyl orthoacetate

amantadine hydrochloride
665-66-7

amantadine hydrochloride

N-(1-adamantyl)acetamide
880-52-4

N-(1-adamantyl)acetamide

Conditions
ConditionsYield
In methanol at 135℃; for 0.25h; Microwave irradiation;100%
2,3,4-trifluorophenyl isocyanate
190774-58-4

2,3,4-trifluorophenyl isocyanate

amantadine hydrochloride
665-66-7

amantadine hydrochloride

1-(adamantan-1-yl)-3-(2,3,4-trifluorophenyl)urea
1338780-86-1

1-(adamantan-1-yl)-3-(2,3,4-trifluorophenyl)urea

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; Inert atmosphere;100%
2,2'-dithiodibenzoic acid dichloride
19602-82-5

2,2'-dithiodibenzoic acid dichloride

amantadine hydrochloride
665-66-7

amantadine hydrochloride

N,N'-bis(1-adamantyl)-2,2'-dithiodibenzamide
847431-86-1

N,N'-bis(1-adamantyl)-2,2'-dithiodibenzamide

Conditions
ConditionsYield
With triethylamine In dichloromethane for 5.5h;98%
With triethylamine In dichloromethane at -15℃; for 0.25h;
poly(ethylene glycol)-carboxylic acid, carboxyl content 6.88E-5 mol/g, Mw = 33300, PDI = 1.1

poly(ethylene glycol)-carboxylic acid, carboxyl content 6.88E-5 mol/g, Mw = 33300, PDI = 1.1

amantadine hydrochloride
665-66-7

amantadine hydrochloride

alpha cyclodextrin
10016-20-3

alpha cyclodextrin

poly(ethylene glycol) 3500, bis[N-(1-adamantyl)aminocarbonyl]-terminated, inclusion complex with α-cyclodextrin, prepared with 1-adamantylamine and proton sponge

poly(ethylene glycol) 3500, bis[N-(1-adamantyl)aminocarbonyl]-terminated, inclusion complex with α-cyclodextrin, prepared with 1-adamantylamine and proton sponge

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 4℃;95%
Benzyl isothiocyanate
622-78-6

Benzyl isothiocyanate

amantadine hydrochloride
665-66-7

amantadine hydrochloride

1-(adamantane-2-yl)-3-benzylthiourea
29456-84-6

1-(adamantane-2-yl)-3-benzylthiourea

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 80℃; for 8h;95%
1-adamantyl bromomethyl ketone
5122-82-7

1-adamantyl bromomethyl ketone

amantadine hydrochloride
665-66-7

amantadine hydrochloride

1-(adamant-1-yl)-2-((adamant-1-yl)amino)ethan-1-one

1-(adamant-1-yl)-2-((adamant-1-yl)amino)ethan-1-one

Conditions
ConditionsYield
With sodium carbonate In ethanol for 15h; Heating;94%
amantadine hydrochloride
665-66-7

amantadine hydrochloride

1-Adamantanamine
768-94-5

1-Adamantanamine

Conditions
ConditionsYield
With sodium chloride; sodium hydroxide In water94%
With sodium hydroxide In water
With sodium hydroxide In dichloromethane; water
4-((3-formyl-4-hydroxyphenyl)diazenyl)benzenesulfonamide
215177-60-9

4-((3-formyl-4-hydroxyphenyl)diazenyl)benzenesulfonamide

amantadine hydrochloride
665-66-7

amantadine hydrochloride

C23H26N4O3S

C23H26N4O3S

Conditions
ConditionsYield
With acetic acid Reflux;94%
2-hydroxy-5-(p-chlorophenylazo)benzaldehyde
27147-07-5

2-hydroxy-5-(p-chlorophenylazo)benzaldehyde

amantadine hydrochloride
665-66-7

amantadine hydrochloride

C23H24ClN3O

C23H24ClN3O

Conditions
ConditionsYield
With acetic acid Reflux;94%
2,4-Dinitrofluorobenzene
70-34-8

2,4-Dinitrofluorobenzene

amantadine hydrochloride
665-66-7

amantadine hydrochloride

N-(2,4-dinitrophenyl)adamantan-1-amine
149874-11-3

N-(2,4-dinitrophenyl)adamantan-1-amine

Conditions
ConditionsYield
With triethylamine In acetonitrile for 48h; Reflux; Darkness;93%
With potassium carbonate; triethylamine In acetonitrile for 48h; pH=8 - 9; Darkness;50%
Boc-Glu-OBn
30924-93-7

Boc-Glu-OBn

amantadine hydrochloride
665-66-7

amantadine hydrochloride

N-(tert-butyloxycarbonyl)-L-glutamic acid α-benzyl ester γ-(1-adamantylamide)
102651-06-9

N-(tert-butyloxycarbonyl)-L-glutamic acid α-benzyl ester γ-(1-adamantylamide)

Conditions
ConditionsYield
With diphenylphosphoranyl azide; diethylamine In N,N-dimethyl-formamide at 0 - 25℃; for 21h;92%
amantadine hydrochloride
665-66-7

amantadine hydrochloride

phenyl isothiocyanate
103-72-0

phenyl isothiocyanate

1-(adamantane-2-yl)-3-phenylthiourea
25444-88-6

1-(adamantane-2-yl)-3-phenylthiourea

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 80℃; for 8h;92%
Phenethyl isothiocyanate
2257-09-2

Phenethyl isothiocyanate

amantadine hydrochloride
665-66-7

amantadine hydrochloride

1-(adamantane-2-yl)-3-phenethylthiourea

1-(adamantane-2-yl)-3-phenethylthiourea

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 80℃; for 8h;92%
amantadine hydrochloride
665-66-7

amantadine hydrochloride

3-aminoadamantan-1-ol
702-82-9

3-aminoadamantan-1-ol

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 10 - 15℃;90%
With sulfuric acid; nitric acid at 0 - 10℃; for 2h;81%
Stage #1: amantadine hydrochloride With sulfuric acid; nitric acid at 0 - 20℃; Inert atmosphere;
Stage #2: With sodium hydroxide In water
72%
sodium metavanadate

sodium metavanadate

water
7732-18-5

water

amantadine hydrochloride
665-66-7

amantadine hydrochloride

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

4C10H15NH3(1+)*2H(1+)*V10O28(6-)*2HCON(CH3)2*2H2O=(C10H15NH3)4(H2V10O28)*2HCON(CH3)2*2H2O

4C10H15NH3(1+)*2H(1+)*V10O28(6-)*2HCON(CH3)2*2H2O=(C10H15NH3)4(H2V10O28)*2HCON(CH3)2*2H2O

Conditions
ConditionsYield
With aq. HCl In water stirring mixture of adamantane deriv., vanadium compd., water and DMF for few sec. at room temp., adjusting pH to 3 by addn. of 0.1 M aqueous HCl; filtration, keeping in air at room temp. for 2 w, elem. anal.;90%
(1R)-4-(2-tert-butoxycarbonylamino-2-carboxyethyl)imidazole-1-carboxylic acid tert-butyl ester

(1R)-4-(2-tert-butoxycarbonylamino-2-carboxyethyl)imidazole-1-carboxylic acid tert-butyl ester

amantadine hydrochloride
665-66-7

amantadine hydrochloride

N,N'-di(tert-butylcarbamate)adamantylamino-D-histidine amide
1190215-11-2

N,N'-di(tert-butylcarbamate)adamantylamino-D-histidine amide

Conditions
ConditionsYield
With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; trimethylamine In dichloromethane at 20℃; Cooling with ice;90%
hydrogenchloride
7647-01-0

hydrogenchloride

18-crown-6 ether
17455-13-9

18-crown-6 ether

amantadine hydrochloride
665-66-7

amantadine hydrochloride

copper dichloride

copper dichloride

2C10H15NH3(1+)*Cu2Cl6(2-)*C12H24O6=(C10H15NH3)2Cu2Cl6(C12H24O6)

2C10H15NH3(1+)*Cu2Cl6(2-)*C12H24O6=(C10H15NH3)2Cu2Cl6(C12H24O6)

Conditions
ConditionsYield
In hydrogenchloride; methanol adamantan-1-aminium chloride, 18-crown-6 were dissolved in MeOH, CuCl2 was added followed by concd. aq. HCl; filtered, slow evapd. at room temp., elam. anal.;90%
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