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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

DL-Mevalonolactone Manufacturer/High quality/Best price/In stock

Cas:674-26-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

DL-Mevalonolactone

Cas:674-26-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory price Cosmetic MEVALONOLACTONE 674-26-0 Manufacturer

Cas:674-26-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

DL-Mevalonic acid δ-lactone

Cas:674-26-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: DL-Mevalonolactone Synonyms: DL-MEVALONOLACTONE;DL-MEVALOLACTONE;DL-MEVALONIC ACID LACTONE;DL-BETA-HYDROXY-BETA-METHYL-DELTA-VALERO-LACTONE;DL-BETA-HYDROXY-BETA-METHYL-GAMMA-VALEROLACTONE;DL-BETA-HYDROXY-BETA-METHYL-G-VAL

674-26-0 DL-Mevalonolactone

Cas:674-26-0

Min.Order:1 Kilogram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

674-26-0 DL-Mevalonolactone

Cas:674-26-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 674-26-0 with best price

Cas:674-26-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Fine chemical DL-Mevalonolactone CAS674-26-0

Cas:674-26-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: DL-Mevalonolactone Synonyms: DL-MEVALONOLACTONE;β-Hydroxy-β-methyl-δ-valerolactone, (±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, (±)-Mev

DL-Mevalonolactone

Cas:674-26-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

2H-Pyran-2-one,tetrahydro-4-hydroxy-4-methyl-

Cas:674-26-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2H-Pyran-2-one,tetrahydro-4-hydroxy-4-methyl-

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

DL-Mevalonic acid lactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Tianjin Kind Pharma Co., Ltd.

Factory direct sales, accept customization. Kind Pharma has its own laboratory, we can do analytical testing for API (Active Pharmaceutical Ingredient), pharmaceutical intermediate, pesticide intermediate, additive and other chemical products, so it

DL-Mevalonolactone

Cas:674-26-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2H-Pyran-2-one,tetrahydro-4-hydroxy-4-methyl-

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Binbo Biological Co., Ltd

GMO-FREE BSE/TSE FREE ALLERGEN FREE PESTICIDES FREE ISO9001 Certified Third Party Test Available Paperwork Supported Plant Audition Accepted Prompt and Secure Shipment Binbo Biological Products Co. Ltd., is a professional high-tech enterp

Natural Mevalonolactone

Cas:674-26-0

Min.Order:1 Kilogram

FOB Price: $5.0 / 50.0

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

DL-Mevalonolactone/High quality/Best price

Cas:674-26-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

DL-Mevalonolactone

Cas:674-26-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

DL-Mevalonic acid lactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Mevalonolactone

Cas:674-26-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

DL-Mevalonic acid lactone cas no. 674-26-0 98%

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

DL-Mevalonic acid lactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

DL-Mevalonic acid delta-lactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

Q1: Are you a manufacturer Answer: Yes, we are factory founded on 2012.Q2: How to contact with us Click "contact supplier" And then send us message the product you interest in, you will get reply within 12 hours.Q3:Which kind of payment terms do you

DL-Mevalonolactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk productiongoods in stockswe have the best competitive price in the marketmeantime,we are committed to service to our every customer Chemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical

DL-Mevalonolactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Tetrahydro-4-hydroxy-4-Methyl-2H-pyran-2-one

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

4-Hydroxy-4-methyltetrahydro-2H-pyran-2-one

Cas:674-26-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

DL-Mevalonolactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:off-white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as prima

DL-Mevalonolactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

DL-Mevalonolactone cas 674-26-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

DL-Mevalonolactone cas 674-26-0

Cas:674-26-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:Moist pale yellow to off white solid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

DL-Mevalonicacidlactone

Cas:674-26-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

3-methyl-1,3,5-pentanetriol
7564-64-9

3-methyl-1,3,5-pentanetriol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With pyridinium chlorochromate In dichloromethane for 4h; Ambient temperature;92%
With aluminum oxide; sodium bromite In dichloromethane for 1.5h; Ambient temperature;85%
With peracetic acid; sodium bromide In ethyl acetate at 39.9℃; for 2h;83%
With 1-methyl-1H-imidazole; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate In acetonitrile at 22℃; for 6h;83%
4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one
118617-84-8

4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water for 10h; Ambient temperature; cleavage of (p-methoxybenzyloxy)methyl protecting group;89%
2,3,5,6-tetrahydro-4-methylpyran-2,4-diol
99720-12-4

2,3,5,6-tetrahydro-4-methylpyran-2,4-diol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium acetate; pyridinium chlorochromate In dichloromethane for 6h; Ambient temperature;82%
mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sulfuric acid for 15h; Reflux;82%
Multi-step reaction with 2 steps
1: tetrabutylammomium bromide / tetrahydrofuran / 4 h / 50 °C / Inert atmosphere
2: pyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
View Scheme
trimethylsilyl acetate
2754-27-0

trimethylsilyl acetate

4-((trimethylsilyl)oxy)-3-butanone
81852-67-7

4-((trimethylsilyl)oxy)-3-butanone

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With lithium diisopropyl amide 1.) THF, -78 deg C, 2 h, 2.) -78 deg C, 2 h;81%
ethyl 3-hydroxy-3-methyl-5-<(2-tetrahydropyranyl)-oxy>pentanoate
80514-97-2

ethyl 3-hydroxy-3-methyl-5-<(2-tetrahydropyranyl)-oxy>pentanoate

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With acetyl chloride In ethanol for 10h; Ambient temperature;80%
With acetyl chloride In ethanol Ambient temperature; overnight;22 g
3-hydroxy-3-methylglutaric anhydride
34695-32-4

3-hydroxy-3-methylglutaric anhydride

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium tetrahydroborate In isopropyl alcohol75.6%
With sodium tetrahydroborate In isopropyl alcohol Ambient temperature;300 mg
With sodium tetrahydroborate In isopropyl alcohol for 24h; Ambient temperature;
Multi-step reaction with 2 steps
1: 1.) CH2Cl2, -20 deg C, 7 days
2: 1.) LiCl, NaBH4; 2.) 10percent KOH / 1.) EtOH, 50 deg C, 24 h; 2.) MeOH, 60 deg C, 4h
View Scheme
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

benzyl 3,5-dihydroxy-3-methylpentanoate
1452161-92-0

benzyl 3,5-dihydroxy-3-methylpentanoate

A

benzyl 2-(4-methyl-2-oxo-1,3-dioxan-4-yl)acetate
1452161-93-1

benzyl 2-(4-methyl-2-oxo-1,3-dioxan-4-yl)acetate

B

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 0.5h; Inert atmosphere;A 64%
B 12%
5-chloro-3-hydroxy-3-methylvaleric acid
128811-87-0

5-chloro-3-hydroxy-3-methylvaleric acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With potassium carbonate; Katamin AB In acetone at 40 - 45℃; for 3h;60%
5-[(4-nitrophenyl)methylcarbamoyloxy]-3-hydroxy-3-methylpentanoic acid
246237-03-6

5-[(4-nitrophenyl)methylcarbamoyloxy]-3-hydroxy-3-methylpentanoic acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; Cyclization; Deprotection;17%
Ketene
463-51-4

Ketene

1-acetoxybutan-3-one
10150-87-5

1-acetoxybutan-3-one

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With diethyl ether; boron trifluoride behandeln des Reaktionsprodukts mit methanol. Kalilauge und anschliessend mit Chlorwasserstoff enthaltendem Methanol;
1,1-diallylethanol
25201-40-5

1,1-diallylethanol

acetic acid
64-19-7

acetic acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With ozone Behandeln des Reaktionsgemisches mit Natriumboranat in Aethanol und Erhitzen des Reaktionsprodukts mit Aluminiumisopropylat in Xylol;
(R/S)-3-methyl-5-hexene-1,3-diol
114580-75-5

(R/S)-3-methyl-5-hexene-1,3-diol

acetic acid
64-19-7

acetic acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With ozone anschliessend mit wss.Wasserstoffperoxid;
3-acetoxy-3-methylpentane-1,5-dioic acid anhydride
87894-65-3

3-acetoxy-3-methylpentane-1,5-dioic acid anhydride

A

4-methyl-5,6-dihydro-2H-pyran-2-one
2381-87-5

4-methyl-5,6-dihydro-2H-pyran-2-one

B

5-O-acetylmevalonic acid
78501-60-7

5-O-acetylmevalonic acid

C

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium tetrahydroborate In isopropyl alcohol for 24h; Ambient temperature; Title compound not separated from byproducts;
t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multistep reaction;
butyl <2-13C,2H3>acetate
120388-51-4

butyl <2-13C,2H3>acetate

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
0.82 g
β-hydroxy-β-methylglutarylhydroxyabscisic acid

β-hydroxy-β-methylglutarylhydroxyabscisic acid

B

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With borane In tetrahydrofuran 1.) -18 deg C, 30 min, 2.) room temp.;A 1.0 mg
B 0.6 mg
3-Hydroxy-3-methyl-4-(2'-morpholin-4-yl-[1,1']binaphthalenyl-2-ylcarbamoyl)-butyric acid methyl ester
94726-38-2, 106402-01-1

3-Hydroxy-3-methyl-4-(2'-morpholin-4-yl-[1,1']binaphthalenyl-2-ylcarbamoyl)-butyric acid methyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With potassium hydroxide; sodium tetrahydroborate; lithium chloride 1.) EtOH, 50 deg C, 24 h; 2.) MeOH, 60 deg C, 4h; Yield given. Multistep reaction;
(+-)-3,5-dihydroxy-3-methyl-valeric acid ethyl ester

(+-)-3,5-dihydroxy-3-methyl-valeric acid ethyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With barium dihydroxide; water at 120℃; Behandeln des erhaltenen Barium-Salzes mit wss.Schwefelsaeure und Erhitzen des Reaktionsprodukts;
(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid ethyl ester

(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid ethyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium hydroxide; ethanol Erwaermen der erhaltenen, ueber das N,N'-Dibenzyl-aethylendiamin-Salz gereinigten (+-)-3,5-Dihydroxy-3-methyl-valeriansaeure unter 0.3 Torr;
(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid methyl ester

(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid methyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With methanol; potassium hydroxide anschliessend mit Chlorwasserstoff enthaltendem Methanol;
(+-)-barium-<3-hydroxy-5,5-dimethoxy-3-methyl valerate >

(+-)-barium-<3-hydroxy-5,5-dimethoxy-3-methyl valerate >

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With hydrogenchloride Behandeln der mit wss.Natronlauge neutralisierten Reaktionsloesung mit Kaliumboranat und anschliessend mit wss.Salzsaeure;
acetic acid
64-19-7

acetic acid

(+-)-5-acetoxy-1,1-dimethoxy-3-methyl-pentan-3-ol

(+-)-5-acetoxy-1,1-dimethoxy-3-methyl-pentan-3-ol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sulfuric acid; dihydrogen peroxide
(R/S)-3-methyl-5-hexene-1,3-diol
114580-75-5

(R/S)-3-methyl-5-hexene-1,3-diol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 285 mg / DMAP; NEt3 / tetrahydrofuran; toluene / 90 h / 20 °C
2: 4-methylmorpholine N-oxide; OsO4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.75 h
3: 409.1 mg / Pb(OAc)4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.17 h
4: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
5: 17 percent / NaOH / methanol / 20 °C
View Scheme
(4-nitrophenyl)methylcarbamic acid 3-hydroxy-3-methyl-5-oxopentyl ester
246236-98-6

(4-nitrophenyl)methylcarbamic acid 3-hydroxy-3-methyl-5-oxopentyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
2: 17 percent / NaOH / methanol / 20 °C
View Scheme
methyl-(4-nitro-phenyl)-carbamic acid 3-hydroxy-3-methyl-hex-5-enyl ester
246237-00-3

methyl-(4-nitro-phenyl)-carbamic acid 3-hydroxy-3-methyl-hex-5-enyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 4-methylmorpholine N-oxide; OsO4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.75 h
2: 409.1 mg / Pb(OAc)4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.17 h
3: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
4: 17 percent / NaOH / methanol / 20 °C
View Scheme
methyl-(4-nitro-phenyl)-carbamic acid 3,5,6-trihydroxy-3-methyl-hexyl ester

methyl-(4-nitro-phenyl)-carbamic acid 3,5,6-trihydroxy-3-methyl-hexyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 409.1 mg / Pb(OAc)4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.17 h
2: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
3: 17 percent / NaOH / methanol / 20 °C
View Scheme
1,1-diallylethanol
25201-40-5

1,1-diallylethanol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) O3, 2.) H2O2 / 1.) CH2Cl2, CH3COOH, -78 deg C, 2.) CH3COOH
2: (CH3CO)2O / 14 h / Ambient temperature
3: 75.6 percent / NaBH4 / propan-2-ol
View Scheme
Multi-step reaction with 3 steps
1: 1.) ozone, acetic acid, 2.) hydrogen peroxide / 1.) methylene dichloride, -78 deg C, 2.) water, reflux, 13 h
2: 673 mg / acetic anhydride / 72 h / 18 °C / further reagents, reaction conditions
3: 300 mg / sodium borohydride / propan-2-ol / Ambient temperature
View Scheme
meglutol
503-49-1

meglutol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: (CH3CO)2O / 14 h / Ambient temperature
2: 75.6 percent / NaBH4 / propan-2-ol
View Scheme
Multi-step reaction with 2 steps
1: 673 mg / acetic anhydride / 72 h / 18 °C / further reagents, reaction conditions
2: 300 mg / sodium borohydride / propan-2-ol / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 16 h / 0 - 20 °C
2: tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 1-methyl-1H-imidazole / acetonitrile / 6 h / 22 °C
View Scheme
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

mevalonolactone
674-26-0

mevalonolactone

4-Methyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-one
100689-33-6, 120445-02-5

4-Methyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-one

Conditions
ConditionsYield
triphenylphosphine hydrobromide In dichloromethane for 7h; Ambient temperature;96%
With lithium hexafluorophosphate In hexane at 0℃; for 4.5h;49%
mevalonolactone
674-26-0

mevalonolactone

4-methyl-5,6-dihydro-2H-pyran-2-one
2381-87-5

4-methyl-5,6-dihydro-2H-pyran-2-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene for 19h; Reflux;93%
With PPA89%
With toluene-4-sulfonic acid In benzene for 20h; Reflux; Dean-Stark;89%
para-methoxybenzyl chloride
88023-78-3

para-methoxybenzyl chloride

mevalonolactone
674-26-0

mevalonolactone

4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one
118617-84-8

4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane for 30h; Ambient temperature;84%
benzyl isothiocyanate
3173-56-6

benzyl isothiocyanate

mevalonolactone
674-26-0

mevalonolactone

Benzyl-carbamic acid 4-methyl-2-oxo-tetrahydro-pyran-4-yl ester
123034-94-6

Benzyl-carbamic acid 4-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Conditions
ConditionsYield
copper(l) chloride In N,N-dimethyl-formamide Ambient temperature;80%
mevalonolactone
674-26-0

mevalonolactone

meglutol
503-49-1

meglutol

Conditions
ConditionsYield
With nitric acid; sodium nitrite at 35 - 40℃; for 5h;76%
With nitric acid at 40℃; for 4h; Cooling with ice;57%
9-ethyl-9H-carbazol-3-ylamine
132-32-1

9-ethyl-9H-carbazol-3-ylamine

mevalonolactone
674-26-0

mevalonolactone

N-(9-ethyl-9H-carbazol-3-yl)-3,5-dihydroxy-3-methylpentanamide
1427185-29-2

N-(9-ethyl-9H-carbazol-3-yl)-3,5-dihydroxy-3-methylpentanamide

Conditions
ConditionsYield
Stage #1: 9-ethyl-9H-carbazol-3-ylamine With trimethylaluminum In toluene at 10 - 35℃; for 0.5h;
Stage #2: mevalonolactone In toluene at 0℃; for 4h;
74%
hexan-1-amine
111-26-2

hexan-1-amine

mevalonolactone
674-26-0

mevalonolactone

1-hexyl-4-methyl-2-piperidin-3-enone
1072454-00-2

1-hexyl-4-methyl-2-piperidin-3-enone

Conditions
ConditionsYield
With 1-butyl-3-methylimidazolium Tetrafluoroborate In 1,4-dioxane at 240℃; for 0.583333h; Microwave irradiation;73%
benzyl bromide
100-39-0

benzyl bromide

mevalonolactone
674-26-0

mevalonolactone

benzyl 3,5-dihydroxy-3-methylpentanoate
1452161-92-0

benzyl 3,5-dihydroxy-3-methylpentanoate

Conditions
ConditionsYield
Stage #1: mevalonolactone With water; potassium hydroxide at 20 - 40℃; for 1h;
Stage #2: benzyl bromide With hydrogenchloride; tetrabutylammomium bromide In tetrahydrofuran; water at 20 - 50℃; for 4h; pH=7 - 8;
69%
2,3,4,5,6-pentafluorobenzylamine
1548-77-2

2,3,4,5,6-pentafluorobenzylamine

mevalonolactone
674-26-0

mevalonolactone

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide
1452162-37-6

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 12h; Inert atmosphere;53%
2,3,4,5,6-pentafluorobenzamide
652-31-3

2,3,4,5,6-pentafluorobenzamide

mevalonolactone
674-26-0

mevalonolactone

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide
1452162-37-6

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20 - 80℃; for 12h; Inert atmosphere;53%
D-(+)-glucosamine hydrochloride
66-84-2

D-(+)-glucosamine hydrochloride

mevalonolactone
674-26-0

mevalonolactone

N-glucosylmevalonamide

N-glucosylmevalonamide

Conditions
ConditionsYield
With sodium hydroxide In water at 55℃; for 5h; Heating;47%
mevalonolactone
674-26-0

mevalonolactone

3,5-dihydroxy-3-methyl-valeraldehyde-(2,4-dinitro-phenylhydrazone)
105338-90-7

3,5-dihydroxy-3-methyl-valeraldehyde-(2,4-dinitro-phenylhydrazone)

Conditions
ConditionsYield
With tetrahydrofuran; lithium aluminium tetrahydride Erwaermen des Reaktionsprodukts mit <2,4-Dinitro-phenyl>-hydrazin und wss.-methanol. HCl;
Benzhydrylamine
91-00-9

Benzhydrylamine

mevalonolactone
674-26-0

mevalonolactone

(+/-)-3,5-dihydroxy-3-methyl-valeric acid benzhydrylamide
5973-99-9

(+/-)-3,5-dihydroxy-3-methyl-valeric acid benzhydrylamide

Conditions
ConditionsYield
at 110℃; for 1h;
mevalonolactone
674-26-0

mevalonolactone

methyl iodide
74-88-4

methyl iodide

3,5-dihydroxy-3-methylpentanoic acid methyl ester
10371-61-6

3,5-dihydroxy-3-methylpentanoic acid methyl ester

Conditions
ConditionsYield
(i) ion-exchange resin + form>, H2O, (ii) Ag2O, (iii) /BRN= 969135/, THF; Multistep reaction;
mevalonolactone
674-26-0

mevalonolactone

3-methyl-1,3,5-pentanetriol
7564-64-9

3-methyl-1,3,5-pentanetriol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran
With lithium aluminium tetrahydride In tetrahydrofuran for 18h; Reflux;2.1 g
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

(R)-methoxytrifluoromethylphenylacetyl chloride
20445-33-4, 39637-99-5

(R)-methoxytrifluoromethylphenylacetyl chloride

mevalonolactone
674-26-0

mevalonolactone

(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 3-hydroxy-3-methyl-4-((R)-1-naphthalen-1-yl-ethylcarbamoyl)-butyl ester
72165-50-5, 72203-59-9

(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 3-hydroxy-3-methyl-4-((R)-1-naphthalen-1-yl-ethylcarbamoyl)-butyl ester

Conditions
ConditionsYield
With pyridine 1.) 70- 80 deg C, 3 h, 2.) RT; Multistep reaction;
tirucallol
79-63-0

tirucallol

mevalonolactone
674-26-0

mevalonolactone

4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol
7448-02-4

4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol

Conditions
ConditionsYield
With arsenite rat liver extracts, phosphate buffer, pH 7.4, sucrose;

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