Product Name

  • Name

    DL-Mevalonolactone

  • EINECS 211-615-0
  • CAS No. 674-26-0
  • Article Data42
  • CAS DataBase
  • Density 1.189 g/cm3
  • Solubility Soluble in ethanol (100 mg/ml-clear to very slightly hazy faint yellow solution), dichloromethane, ethyl acetate, and methanol
  • Melting Point 28 °C(lit.)
  • Formula C6H10 O3
  • Boiling Point 145-150 °C5 mm Hg(lit.)
  • Molecular Weight 130.144
  • Flash Point >230 °F
  • Transport Information
  • Appearance Moist pale yellow to off white solid
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 674-26-0 (DL-Mevalonolactone)
  • Hazard Symbols
  • Synonyms 2H-Pyran-2-one,tetrahydro-4-hydroxy-4-methyl-, (?à)- (8CI); (RS)-Mevalonolactone; (?à)-Mevalolactone; (?à)-Mevalonolactone; DL-Mevalonic acid lactone;DL-Mevalonic acid d-lactone; DL-Mevalonolactone; MVSL; Mevalolactone; Mevalonic acid lactone;Mevalonic acid d-lactone;Mevalonic lactone; Mevalonolactone; NSC 90804; b-Hydroxy-b-methyl-d-valerolactone
  • PSA 46.53000
  • LogP 0.07440

Synthetic route

3-methyl-1,3,5-pentanetriol
7564-64-9

3-methyl-1,3,5-pentanetriol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With pyridinium chlorochromate In dichloromethane for 4h; Ambient temperature;92%
With aluminum oxide; sodium bromite In dichloromethane for 1.5h; Ambient temperature;85%
With peracetic acid; sodium bromide In ethyl acetate at 39.9℃; for 2h;83%
With 1-methyl-1H-imidazole; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate In acetonitrile at 22℃; for 6h;83%
4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one
118617-84-8

4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water for 10h; Ambient temperature; cleavage of (p-methoxybenzyloxy)methyl protecting group;89%
2,3,5,6-tetrahydro-4-methylpyran-2,4-diol
99720-12-4

2,3,5,6-tetrahydro-4-methylpyran-2,4-diol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium acetate; pyridinium chlorochromate In dichloromethane for 6h; Ambient temperature;82%
D,L-mevalonic acid
150-97-0, 690-72-2, 17817-88-8, 32451-23-3

D,L-mevalonic acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sulfuric acid for 15h; Reflux;82%
Multi-step reaction with 2 steps
1: tetrabutylammomium bromide / tetrahydrofuran / 4 h / 50 °C / Inert atmosphere
2: pyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
View Scheme
trimethylsilyl acetate
2754-27-0

trimethylsilyl acetate

4-((trimethylsilyl)oxy)-3-butanone
81852-67-7

4-((trimethylsilyl)oxy)-3-butanone

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With lithium diisopropyl amide 1.) THF, -78 deg C, 2 h, 2.) -78 deg C, 2 h;81%
ethyl 3-hydroxy-3-methyl-5-<(2-tetrahydropyranyl)-oxy>pentanoate
80514-97-2

ethyl 3-hydroxy-3-methyl-5-<(2-tetrahydropyranyl)-oxy>pentanoate

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With acetyl chloride In ethanol for 10h; Ambient temperature;80%
With acetyl chloride In ethanol Ambient temperature; overnight;22 g
3-hydroxy-3-methylglutaric anhydride
34695-32-4

3-hydroxy-3-methylglutaric anhydride

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium tetrahydroborate In isopropyl alcohol75.6%
With sodium tetrahydroborate In isopropyl alcohol Ambient temperature;300 mg
With sodium tetrahydroborate In isopropyl alcohol for 24h; Ambient temperature;
Multi-step reaction with 2 steps
1: 1.) CH2Cl2, -20 deg C, 7 days
2: 1.) LiCl, NaBH4; 2.) 10percent KOH / 1.) EtOH, 50 deg C, 24 h; 2.) MeOH, 60 deg C, 4h
View Scheme
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

benzyl 3,5-dihydroxy-3-methylpentanoate
1452161-92-0

benzyl 3,5-dihydroxy-3-methylpentanoate

A

benzyl 2-(4-methyl-2-oxo-1,3-dioxan-4-yl)acetate
1452161-93-1

benzyl 2-(4-methyl-2-oxo-1,3-dioxan-4-yl)acetate

B

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 0.5h; Inert atmosphere;A 64%
B 12%
...Expand
5-chloro-3-hydroxy-3-methylvaleric acid
128811-87-0

5-chloro-3-hydroxy-3-methylvaleric acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With potassium carbonate; Katamin AB In acetone at 40 - 45℃; for 3h;60%
5-[(4-nitrophenyl)methylcarbamoyloxy]-3-hydroxy-3-methylpentanoic acid
246237-03-6

5-[(4-nitrophenyl)methylcarbamoyloxy]-3-hydroxy-3-methylpentanoic acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; Cyclization; Deprotection;17%
Ketene
463-51-4

Ketene

1-acetoxybutan-3-one
10150-87-5

1-acetoxybutan-3-one

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With diethyl ether; boron trifluoride behandeln des Reaktionsprodukts mit methanol. Kalilauge und anschliessend mit Chlorwasserstoff enthaltendem Methanol;
1,1-diallylethanol
25201-40-5

1,1-diallylethanol

acetic acid
64-19-7

acetic acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With ozone Behandeln des Reaktionsgemisches mit Natriumboranat in Aethanol und Erhitzen des Reaktionsprodukts mit Aluminiumisopropylat in Xylol;
(R/S)-3-methyl-5-hexene-1,3-diol
114580-75-5

(R/S)-3-methyl-5-hexene-1,3-diol

acetic acid
64-19-7

acetic acid

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With ozone anschliessend mit wss.Wasserstoffperoxid;
3-acetoxy-3-methylpentane-1,5-dioic acid anhydride
87894-65-3

3-acetoxy-3-methylpentane-1,5-dioic acid anhydride

A

4-methyl-5,6-dihydro-2H-pyran-2-one
2381-87-5

4-methyl-5,6-dihydro-2H-pyran-2-one

B

5-O-acetylmevalonic acid
78501-60-7

5-O-acetylmevalonic acid

C

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium tetrahydroborate In isopropyl alcohol for 24h; Ambient temperature; Title compound not separated from byproducts;
...Expand
t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multistep reaction;
butyl <2-13C,2H3>acetate
120388-51-4

butyl <2-13C,2H3>acetate

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
0.82 g
β-hydroxy-β-methylglutarylhydroxyabscisic acid

β-hydroxy-β-methylglutarylhydroxyabscisic acid

(+/-)-Phaseic acid
24394-14-7, 127516-44-3, 128821-87-4

(+/-)-Phaseic acid

B

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With borane In tetrahydrofuran 1.) -18 deg C, 30 min, 2.) room temp.;A 1.0 mg
B 0.6 mg
3-Hydroxy-3-methyl-4-(2'-morpholin-4-yl-[1,1']binaphthalenyl-2-ylcarbamoyl)-butyric acid methyl ester
94726-38-2, 106402-01-1

3-Hydroxy-3-methyl-4-(2'-morpholin-4-yl-[1,1']binaphthalenyl-2-ylcarbamoyl)-butyric acid methyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With potassium hydroxide; sodium tetrahydroborate; lithium chloride 1.) EtOH, 50 deg C, 24 h; 2.) MeOH, 60 deg C, 4h; Yield given. Multistep reaction;
(+-)-3,5-dihydroxy-3-methyl-valeric acid ethyl ester

(+-)-3,5-dihydroxy-3-methyl-valeric acid ethyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With barium dihydroxide; water at 120℃; Behandeln des erhaltenen Barium-Salzes mit wss.Schwefelsaeure und Erhitzen des Reaktionsprodukts;
(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid ethyl ester

(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid ethyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sodium hydroxide; ethanol Erwaermen der erhaltenen, ueber das N,N'-Dibenzyl-aethylendiamin-Salz gereinigten (+-)-3,5-Dihydroxy-3-methyl-valeriansaeure unter 0.3 Torr;
(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid methyl ester

(+-)-5-acetoxy-3-hydroxy-3-methyl-valeric acid methyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With methanol; potassium hydroxide anschliessend mit Chlorwasserstoff enthaltendem Methanol;
(+-)-barium-<3-hydroxy-5,5-dimethoxy-3-methyl valerate >

(+-)-barium-<3-hydroxy-5,5-dimethoxy-3-methyl valerate >

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With hydrogenchloride Behandeln der mit wss.Natronlauge neutralisierten Reaktionsloesung mit Kaliumboranat und anschliessend mit wss.Salzsaeure;
acetic acid
64-19-7

acetic acid

(+-)-5-acetoxy-1,1-dimethoxy-3-methyl-pentan-3-ol

(+-)-5-acetoxy-1,1-dimethoxy-3-methyl-pentan-3-ol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
With sulfuric acid; dihydrogen peroxide
(R/S)-3-methyl-5-hexene-1,3-diol
114580-75-5

(R/S)-3-methyl-5-hexene-1,3-diol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 285 mg / DMAP; NEt3 / tetrahydrofuran; toluene / 90 h / 20 °C
2: 4-methylmorpholine N-oxide; OsO4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.75 h
3: 409.1 mg / Pb(OAc)4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.17 h
4: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
5: 17 percent / NaOH / methanol / 20 °C
View Scheme
(4-nitrophenyl)methylcarbamic acid 3-hydroxy-3-methyl-5-oxopentyl ester
246236-98-6

(4-nitrophenyl)methylcarbamic acid 3-hydroxy-3-methyl-5-oxopentyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
2: 17 percent / NaOH / methanol / 20 °C
View Scheme
methyl-(4-nitro-phenyl)-carbamic acid 3-hydroxy-3-methyl-hex-5-enyl ester
246237-00-3

methyl-(4-nitro-phenyl)-carbamic acid 3-hydroxy-3-methyl-hex-5-enyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 4-methylmorpholine N-oxide; OsO4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.75 h
2: 409.1 mg / Pb(OAc)4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.17 h
3: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
4: 17 percent / NaOH / methanol / 20 °C
View Scheme
methyl-(4-nitro-phenyl)-carbamic acid 3,5,6-trihydroxy-3-methyl-hexyl ester

methyl-(4-nitro-phenyl)-carbamic acid 3,5,6-trihydroxy-3-methyl-hexyl ester

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 409.1 mg / Pb(OAc)4 / CH2Cl2; H2O; 2-methyl-propan-2-ol / 0.17 h
2: 77 percent / KMnO4 / diethyl ether; aq. phosphate buffer; 2-methyl-propan-2-ol / 0.08 h / 20 °C / pH 7.4
3: 17 percent / NaOH / methanol / 20 °C
View Scheme
1,1-diallylethanol
25201-40-5

1,1-diallylethanol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) O3, 2.) H2O2 / 1.) CH2Cl2, CH3COOH, -78 deg C, 2.) CH3COOH
2: (CH3CO)2O / 14 h / Ambient temperature
3: 75.6 percent / NaBH4 / propan-2-ol
View Scheme
Multi-step reaction with 3 steps
1: 1.) ozone, acetic acid, 2.) hydrogen peroxide / 1.) methylene dichloride, -78 deg C, 2.) water, reflux, 13 h
2: 673 mg / acetic anhydride / 72 h / 18 °C / further reagents, reaction conditions
3: 300 mg / sodium borohydride / propan-2-ol / Ambient temperature
View Scheme
meglutol
503-49-1

meglutol

mevalonolactone
674-26-0

mevalonolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: (CH3CO)2O / 14 h / Ambient temperature
2: 75.6 percent / NaBH4 / propan-2-ol
View Scheme
Multi-step reaction with 2 steps
1: 673 mg / acetic anhydride / 72 h / 18 °C / further reagents, reaction conditions
2: 300 mg / sodium borohydride / propan-2-ol / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 16 h / 0 - 20 °C
2: tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 1-methyl-1H-imidazole / acetonitrile / 6 h / 22 °C
View Scheme
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

mevalonolactone
674-26-0

mevalonolactone

4-Methyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-one
100689-33-6, 120445-02-5

4-Methyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-one

Conditions
ConditionsYield
triphenylphosphine hydrobromide In dichloromethane for 7h; Ambient temperature;96%
With lithium hexafluorophosphate In hexane at 0℃; for 4.5h;49%
mevalonolactone
674-26-0

mevalonolactone

4-methyl-5,6-dihydro-2H-pyran-2-one
2381-87-5

4-methyl-5,6-dihydro-2H-pyran-2-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene for 19h; Reflux;93%
With PPA89%
With toluene-4-sulfonic acid In benzene for 20h; Reflux; Dean-Stark;89%
para-methoxybenzyl chloride
88023-78-3

para-methoxybenzyl chloride

mevalonolactone
674-26-0

mevalonolactone

4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one
118617-84-8

4-(4-Methoxy-benzyloxymethoxy)-4-methyl-tetrahydro-pyran-2-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane for 30h; Ambient temperature;84%
benzyl isothiocyanate
3173-56-6

benzyl isothiocyanate

mevalonolactone
674-26-0

mevalonolactone

Benzyl-carbamic acid 4-methyl-2-oxo-tetrahydro-pyran-4-yl ester
123034-94-6

Benzyl-carbamic acid 4-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Conditions
ConditionsYield
copper(l) chloride In N,N-dimethyl-formamide Ambient temperature;80%
mevalonolactone
674-26-0

mevalonolactone

meglutol
503-49-1

meglutol

Conditions
ConditionsYield
With nitric acid; sodium nitrite at 35 - 40℃; for 5h;76%
With nitric acid at 40℃; for 4h; Cooling with ice;57%
9-ethyl-9H-carbazol-3-ylamine
132-32-1

9-ethyl-9H-carbazol-3-ylamine

mevalonolactone
674-26-0

mevalonolactone

N-(9-ethyl-9H-carbazol-3-yl)-3,5-dihydroxy-3-methylpentanamide
1427185-29-2

N-(9-ethyl-9H-carbazol-3-yl)-3,5-dihydroxy-3-methylpentanamide

Conditions
ConditionsYield
Stage #1: 9-ethyl-9H-carbazol-3-ylamine With trimethylaluminum In toluene at 10 - 35℃; for 0.5h;
Stage #2: mevalonolactone In toluene at 0℃; for 4h;		74%
hexan-1-amine
111-26-2

hexan-1-amine

mevalonolactone
674-26-0

mevalonolactone

1-hexyl-4-methyl-2-piperidin-3-enone
1072454-00-2

1-hexyl-4-methyl-2-piperidin-3-enone

Conditions
ConditionsYield
With 1-butyl-3-methylimidazolium Tetrafluoroborate In 1,4-dioxane at 240℃; for 0.583333h; Microwave irradiation;73%
benzyl bromide
100-39-0

benzyl bromide

mevalonolactone
674-26-0

mevalonolactone

benzyl 3,5-dihydroxy-3-methylpentanoate
1452161-92-0

benzyl 3,5-dihydroxy-3-methylpentanoate

Conditions
ConditionsYield
Stage #1: mevalonolactone With water; potassium hydroxide at 20 - 40℃; for 1h;
Stage #2: benzyl bromide With hydrogenchloride; tetrabutylammomium bromide In tetrahydrofuran; water at 20 - 50℃; for 4h; pH=7 - 8;		69%
2,3,4,5,6-pentafluorobenzylamine
1548-77-2

2,3,4,5,6-pentafluorobenzylamine

mevalonolactone
674-26-0

mevalonolactone

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide
1452162-37-6

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 12h; Inert atmosphere;53%
2,3,4,5,6-pentafluorobenzamide
652-31-3

2,3,4,5,6-pentafluorobenzamide

mevalonolactone
674-26-0

mevalonolactone

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide
1452162-37-6

3,5-Dihydroxy-3-methyl-N-((perfluorophenyl)methyl)pentanamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20 - 80℃; for 12h; Inert atmosphere;53%
D-(+)-glucosamine hydrochloride
66-84-2

D-(+)-glucosamine hydrochloride

mevalonolactone
674-26-0

mevalonolactone

N-glucosylmevalonamide

N-glucosylmevalonamide

Conditions
ConditionsYield
With sodium hydroxide In water at 55℃; for 5h; Heating;47%
mevalonolactone
674-26-0

mevalonolactone

3,5-dihydroxy-3-methyl-valeraldehyde-(2,4-dinitro-phenylhydrazone)
105338-90-7

3,5-dihydroxy-3-methyl-valeraldehyde-(2,4-dinitro-phenylhydrazone)

Conditions
ConditionsYield
With tetrahydrofuran; lithium aluminium tetrahydride Erwaermen des Reaktionsprodukts mit <2,4-Dinitro-phenyl>-hydrazin und wss.-methanol. HCl;
Benzhydrylamine
91-00-9

Benzhydrylamine

mevalonolactone
674-26-0

mevalonolactone

(+/-)-3,5-dihydroxy-3-methyl-valeric acid benzhydrylamide
5973-99-9

(+/-)-3,5-dihydroxy-3-methyl-valeric acid benzhydrylamide

Conditions
ConditionsYield
at 110℃; for 1h;
mevalonolactone
674-26-0

mevalonolactone

methyl iodide
74-88-4

methyl iodide

3,5-dihydroxy-3-methylpentanoic acid methyl ester
10371-61-6

3,5-dihydroxy-3-methylpentanoic acid methyl ester

Conditions
ConditionsYield
(i) ion-exchange resin + form>, H2O, (ii) Ag2O, (iii) /BRN= 969135/, THF; Multistep reaction;
mevalonolactone
674-26-0

mevalonolactone

3-methyl-1,3,5-pentanetriol
7564-64-9

3-methyl-1,3,5-pentanetriol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran
With lithium aluminium tetrahydride In tetrahydrofuran for 18h; Reflux;2.1 g
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

(R)-methoxytrifluoromethylphenylacetyl chloride
20445-33-4, 39637-99-5

(R)-methoxytrifluoromethylphenylacetyl chloride

mevalonolactone
674-26-0

mevalonolactone

(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 3-hydroxy-3-methyl-4-((R)-1-naphthalen-1-yl-ethylcarbamoyl)-butyl ester
72165-50-5, 72203-59-9

(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 3-hydroxy-3-methyl-4-((R)-1-naphthalen-1-yl-ethylcarbamoyl)-butyl ester

Conditions
ConditionsYield
With pyridine 1.) 70- 80 deg C, 3 h, 2.) RT; Multistep reaction;
...Expand
tirucallol
79-63-0

tirucallol

mevalonolactone
674-26-0

mevalonolactone

4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol
7448-02-4

4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol

Conditions
ConditionsYield
With arsenite rat liver extracts, phosphate buffer, pH 7.4, sucrose;

DL-Mevalonolactone Chemical Properties

Product Name: DL-Mevalonolactone (CAS NO.674-26-0)

Molecular Formula: C6H10O3
Molecular Weight: 130.14g/mol
Mol File: 674-26-0.mol
EINECS: 211-615-0
Melting Point: 28 °C(lit.)
Boiling point: 274.9 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 126.8 °C
Density: 1.189 g/cm3
Refractive index: n20/D 1.473(lit.)
Index of Refraction: 1.478  Molar Refractivity: 30.99 cm3 
Molar Volume: 109.4 cm3 
Surface Tension: 42.5 dyne/cm
Enthalpy of Vaporization: 59.6 kJ/mol
Vapour Pressure: 0.000662 mmHg at 25°C
XLogP3-AA: -0.3
H-Bond Donor: 1
H-Bond Acceptor: 3
Structure Descriptors of DL-Mevalonolactone (CAS NO.674-26-0):
  IUPAC Name: 4-hydroxy-4-methyloxan-2-one
  Canonical SMILES: CC1(CCOC(=O)C1)O
  InChI: InChI=1S/C6H10O3/c1-6(8)2-3-9-5(7)4-6/h8H,2-4H2,1H3 
  InChIKey: JYVXNLLUYHCIIH-UHFFFAOYSA-N
Product Categories: Pale Yellow OilHeterocycles; Metabolites & Impurities

DL-Mevalonolactone Safety Profile

Safety Information of DL-Mevalonolactone (CAS NO.674-26-0):
WGK Germany: 3
F: 3-10

DL-Mevalonolactone Specification

 DL-Mevalonolactone , its CAS NO. is 674-26-0, the synonyms are DL-Mevalonic acid lactone ; (4R)-4-Hydroxy-4-methyl-oxan-2-one ; (+/-)-Tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one .

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