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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

D-pantothenic acid

Cas:79-83-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality D-Pantothenic Acid supplier in China

Cas:79-83-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

Top Grade Pantothenic acid powder vitamin b5 Cas:79-83-4

Cas:79-83-4

Min.Order:1 Kilogram

FOB Price: $28.0 / 60.0

Type:Manufacturers

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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial since 1987 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We can do dif

99% up by HPLC D-PANTOTHENIC ACID/Pantothenic acid/ Vitamin B5 79-83-4

Cas:79-83-4

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High quality D-Pantothenic acid powder with factory price

Cas:79-83-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

D-Pantothenic acid

Cas:79-83-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM D-PANTOTHENIC ACID

Cas:79-83-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 79-83-4 with competitive price

Cas:79-83-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS 79-83-4 ,D-PANTOTHENIC ACID

Cas:79-83-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

D-Pantothenic acid 79-83-4

Cas:79-83-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

High Purity D-Pantothenic acid/ D-VITAMIN B(5)

Cas:79-83-4

Min.Order:10 Gram

FOB Price: $3.6

Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

D-PANTOTHENIC ACID Feed Drug Additives

Cas:79-83-4

Min.Order:1 Kilogram

FOB Price: $20.0 / 50.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

D-PANTOTHENIC ACID CAS:79-83-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermed

D-PANTOTHENIC ACID CAS:79-83-4

Cas:79-83-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

D-Pantothenic acid

Cas:79-83-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

D-Pantothenic acid

Cas:79-83-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Xi'an Yinherb Bio-Tech Co., Ltd.

Xi'an Yinherb Bio-Tech Co., Ltd was founded in 2009, We have more than 10 experienced doctors and scientists and professional managers, specializing in Nootropics, Sarms and Peptides researching and developing, and become the lead

Vitamin B5 fine powder

Cas:79-83-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

Q1: Are you a manufacturer?Answer: Yes, we are factory founded on 2002. Q2: How to contact with us?Click "contact supplier" And then send us message the product you interest in, you will get reply within 12 hours. Q3:Which kind of payment terms do yo

High quality D-Pantothenic acid powder with factory price

Cas:79-83-4

Min.Order:0

Negotiable

Type:Trading Company

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Triumph International Development Limilted

Appearance:off-white to white solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:By Sea/Air/Courier Port:Qingdao

D-PANTOTHENIC ACID 79-83-4

Cas:79-83-4

Min.Order:1 Gram

FOB Price: $16.0 / 20.0

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

D-Pantothenic acid

Cas:79-83-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

D-PANTOTHENIC ACID

Cas:79-83-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hebei Miheng Trading Co., Ltd.

D-PANTOTHENIC ACID CAS 79-83-4 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly.

D-PANTOTHENIC ACID CAS 79-83-4

Cas:79-83-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply D-Pantothenic acid

Cas:79-83-4

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

D-Pantothenic acid

Cas:79-83-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi New nine Material Technology Co., Ltd.

Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D

D-pantothenic acid CAS NO.79-83-4

Cas:79-83-4

Min.Order:10 Gram

FOB Price: $5.0 / 10.0

Type:Trading Company

inquiry

Hefei Zhaobo Technology Co., Ltd.

D-PANTOTHENIC ACID CAS 79-83-4 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control

D-PANTOTHENIC ACID CAS 79-83-4

Cas:79-83-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality D-Pantothenic Acid

Cas:79-83-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

D-PANTOTHENIC ACID

Cas:79-83-4

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

D-Pantothenic acid

Cas:79-83-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best OfferD-Pantothenic acid

Cas:79-83-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High qu

Pharmaceutical Raw Powder D-Pantothenic acid CAS 79-83-4

Cas:79-83-4

Min.Order:5 Gram

Negotiable

Type:Other

inquiry

Synthetic route

calcium (R)-pantothenate
137-08-6

calcium (R)-pantothenate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With oxalic acid In water at 20℃; for 2h;95.11%
With (1S)-10-camphorsulfonic acid; trifluoroacetic acid at 0℃;
With Amberlite IR-120 In water Inert atmosphere;
With oxalic acid In water at 20℃; for 2h;
(R)-Pantolacton
599-04-2

(R)-Pantolacton

alkali salt of/the/ 3-amino-propionic acid

alkali salt of/the/ 3-amino-propionic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With water at 20℃;
With methanol at 20℃;
With isopropyl alcohol bei Siedetemperatur;
(R,E)-benzyl 3-(2,4-dihydroxy-3,3-dimethylbutanamido)acrylate
1265205-80-8

(R,E)-benzyl 3-(2,4-dihydroxy-3,3-dimethylbutanamido)acrylate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol for 24h; Inert atmosphere;86%
DL-pantothenic acid

DL-pantothenic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With Cinchonidin
With Quinine
With quinine methohydroxide
With quinine methohydroxide
With Quinine
(R)-pantoate

(R)-pantoate

2-butenedioic acid
6915-18-0

2-butenedioic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With pantothenate synthetase; aspartate-α-decarboxylase; 3-methylaspartate ammonia lyase; ammonium chloride; ATP; magnesium chloride In aq. buffer at 25℃; for 24h; pH=9; Enzymatic reaction;70%
sodium salt of/the/ (R)-2.4-diacetoxy-3.3-dimethyl-butyric acid

sodium salt of/the/ (R)-2.4-diacetoxy-3.3-dimethyl-butyric acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With thionyl chloride Umsetzung des gebildeten Saeurechlorids mit 3-Amino-propionsaeure-aethylester in Pyridin und Verseifung des Reaktionsprodukts mit aethanol.NaOH;
With thionyl chloride Umsetzung des gebildeten Saeurechlorids mit 3-Amino-propionsaeure-aethylester in Pyridin und Verseifung des Reaktionsprodukts mit wss.Ba(OH)2;
3-[(R)-2-(benzyloxy)-4-hydroxy-3,3-dimethylbutylamino]propanoic acid

3-[(R)-2-(benzyloxy)-4-hydroxy-3,3-dimethylbutylamino]propanoic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol for 24h;92%
3-amino-propionic acid ethyl ester
924-73-2

3-amino-propionic acid ethyl ester

(-)(R)-pantolactone

(-)(R)-pantolactone

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
at 70℃; Hydrolyse des Reaktionsprodukts mit 0.5n-Ba(OH)2 bei 20grad;
at 70℃; Hydrolyse des Reaktionsprodukts mit 0.5n-Ba(OH)2 bei 20grad;
3-amino propanoic acid
107-95-9

3-amino propanoic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
durch Escherichia coli;
durch Diphtherie-Bazillen;
durch verschiedene Hefen;
3-amino propanoic acid
107-95-9

3-amino propanoic acid

sodium salt of/the/ (+)(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid

sodium salt of/the/ (+)(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
at 180℃;
N-formyl-(R)-2,2,5,5-tetramethyl-[1,3]dioxane-4-carboxylic acid amide

N-formyl-(R)-2,2,5,5-tetramethyl-[1,3]dioxane-4-carboxylic acid amide

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: benzene / 19 h / 95 °C / Inert atmosphere
2: bismuth(III) chloride / water; acetonitrile / 3 h / 20 °C / Inert atmosphere
3: palladium 10% on activated carbon; hydrogen / methanol / 24 h / Inert atmosphere
View Scheme
(R,E)-benzyl 3-(2,2,5,5-tetramethyl-1,3-dioxane-4-carboxamido)acrylate
1265205-79-5

(R,E)-benzyl 3-(2,2,5,5-tetramethyl-1,3-dioxane-4-carboxamido)acrylate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bismuth(III) chloride / water; acetonitrile / 3 h / 20 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / methanol / 24 h / Inert atmosphere
View Scheme
(R)-2,4-Dihydroxy-3,3-dimethylbutyramide
27778-35-4

(R)-2,4-Dihydroxy-3,3-dimethylbutyramide

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: pyridinium p-toluenesulfonate / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.08 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: benzene / 19 h / 95 °C / Inert atmosphere
4.1: bismuth(III) chloride / water; acetonitrile / 3 h / 20 °C / Inert atmosphere
5.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h / Inert atmosphere
View Scheme
(R)-Pantolacton
599-04-2

(R)-Pantolacton

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: ammonia / Inert atmosphere
2.1: pyridinium p-toluenesulfonate / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 0.08 h / 0 °C / Inert atmosphere
3.2: 0 - 20 °C / Inert atmosphere
4.1: benzene / 19 h / 95 °C / Inert atmosphere
5.1: bismuth(III) chloride / water; acetonitrile / 3 h / 20 °C / Inert atmosphere
6.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h / Inert atmosphere
View Scheme
(R)-2,2,5,5-Tetramethyl-1,3-dioxane-4-carboxamide
285141-00-6

(R)-2,2,5,5-Tetramethyl-1,3-dioxane-4-carboxamide

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.08 h / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: benzene / 19 h / 95 °C / Inert atmosphere
3.1: bismuth(III) chloride / water; acetonitrile / 3 h / 20 °C / Inert atmosphere
4.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h / Inert atmosphere
View Scheme
pantothenic acid sodium salt
867-81-2

pantothenic acid sodium salt

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With Amberlite IR-120 (H+-form) In water
With Dowex 50x8 (H+) In water
(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-(prop-2-yn-1-ylamino)propyl)butanamide

(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-(prop-2-yn-1-ylamino)propyl)butanamide

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With pantetheinase; water Enzymatic reaction;
3-amino propanoic acid
107-95-9

3-amino propanoic acid

(+)(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-lactone

(+)(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-lactone

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
unter Einw. von Proteus morganii;
unter Einw. von Clostridium septicum;
unter Einw. von einem Stamm haemolytischer Streptococcen;
D-pantoic acid
1112-33-0

D-pantoic acid

3-amino propanoic acid
107-95-9

3-amino propanoic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
unter Einw. von Proteus morganii;
unter Einw. von einem Stamm haemolytischer Streptococcen;
unter Einw. von Clostridium septicum;
(R)-Pantolacton
599-04-2

(R)-Pantolacton

3-amino propanoic acid
107-95-9

3-amino propanoic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With pantothenase UK-1 at 25℃; Equilibrium constant;
With 2-methoxy-ethanol; calcium
at 155 - 180℃;
pantothenol
81-13-0

pantothenol

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With barium permanganate; sulfuric acid
im Organismus von Ratten;
(R)-3-(benzyloxy)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethylpropan-1-ol
895532-69-1

(R)-3-(benzyloxy)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethylpropan-1-ol

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: dmap; triethylamine / dichloromethane / 0 °C
1.2: 20 °C
2.1: acetic acid / 20 °C
3.1: sodium periodate / methanol; water
4.1: sodium dihydrogenphosphate; sodium chlorite / methanol; dichloromethane; water / 20 °C
5.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
5.2: 16 h / 20 °C
6.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
7.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
(R)-3-(benzyloxy)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethylpropyl acetate
1377411-61-4

(R)-3-(benzyloxy)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethylpropyl acetate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: acetic acid / 20 °C
2.1: sodium periodate / methanol; water
3.1: sodium dihydrogenphosphate; sodium chlorite / methanol; dichloromethane; water / 20 °C
4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
4.2: 16 h / 20 °C
5.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
6.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
(3R,4R)-3-(benzyloxy)-4,5-dihydroxy-2,2-dimethylpentyl acetate
1377411-62-5

(3R,4R)-3-(benzyloxy)-4,5-dihydroxy-2,2-dimethylpentyl acetate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sodium periodate / methanol; water
2.1: sodium dihydrogenphosphate; sodium chlorite / methanol; dichloromethane; water / 20 °C
3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
3.2: 16 h / 20 °C
4.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
5.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
(R)-3-(benzyloxy)-2,2-dimethyl-4-oxobutyl acetate
1377411-63-6

(R)-3-(benzyloxy)-2,2-dimethyl-4-oxobutyl acetate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium dihydrogenphosphate; sodium chlorite / methanol; dichloromethane; water / 20 °C
2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
2.2: 16 h / 20 °C
3.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
4.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
(2R)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoic acid
1377411-64-7

(2R)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
1.2: 16 h / 20 °C
2.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
3.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
methyl 3-[(R)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoylamino]propanoate
1377411-65-8

methyl 3-[(R)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoylamino]propanoate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
2: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
ethyl 3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2,2-dimethylpropanoate

ethyl 3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2,2-dimethylpropanoate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1.1: Dess-Martin periodane / dichloromethane / 4 h / 20 °C
2.1: sodium tetrahydroborate / methanol / 1 h / -40 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
3.2: 20 °C
4.1: lithium aluminium tetrahydride / diethyl ether / 0 °C
5.1: dmap; triethylamine / dichloromethane / 0 °C
5.2: 20 °C
6.1: acetic acid / 20 °C
7.1: sodium periodate / methanol; water
8.1: sodium dihydrogenphosphate; sodium chlorite / methanol; dichloromethane; water / 20 °C
9.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
9.2: 16 h / 20 °C
10.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
11.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
(R)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2,2-dimethylpropanoate
1377411-59-0

(R)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2,2-dimethylpropanoate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
1.2: 20 °C
2.1: lithium aluminium tetrahydride / diethyl ether / 0 °C
3.1: dmap; triethylamine / dichloromethane / 0 °C
3.2: 20 °C
4.1: acetic acid / 20 °C
5.1: sodium periodate / methanol; water
6.1: sodium dihydrogenphosphate; sodium chlorite / methanol; dichloromethane; water / 20 °C
7.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
7.2: 16 h / 20 °C
8.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
9.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
ethyl (R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3-oxopropanoate
1377411-50-1

ethyl (R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3-oxopropanoate

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1.1: sodium tetrahydroborate / methanol / 1 h / -40 °C
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
2.2: 20 °C
3.1: lithium aluminium tetrahydride / diethyl ether / 0 °C
4.1: dmap; triethylamine / dichloromethane / 0 °C
4.2: 20 °C
5.1: acetic acid / 20 °C
6.1: sodium periodate / methanol; water
7.1: sodium dihydrogenphosphate; sodium chlorite / methanol; dichloromethane; water / 20 °C
8.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C
8.2: 16 h / 20 °C
9.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 3 h / 0 - 20 °C
10.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h
View Scheme
pantothenic acid
79-83-4

pantothenic acid

acetic anhydride
108-24-7

acetic anhydride

N-[(2R)-2,4-diacetoxy-3,3-dimethylbutanoyl]-β-alanine
96199-41-6

N-[(2R)-2,4-diacetoxy-3,3-dimethylbutanoyl]-β-alanine

Conditions
ConditionsYield
With iodine at 0 - 20℃;97%
pantothenic acid
79-83-4

pantothenic acid

2-Methoxypropene
116-11-0

2-Methoxypropene

3-{[(4R)-2,2,5,5-tetramethyl-1,3-dioxan-4-yl]carbonylamino}propionic acid
167308-62-5

3-{[(4R)-2,2,5,5-tetramethyl-1,3-dioxan-4-yl]carbonylamino}propionic acid

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetone at 0 - 20℃; for 0.666667h;95%
With toluene-4-sulfonic acid In acetone at 0 - 20℃; for 0.75h; Inert atmosphere;
With toluene-4-sulfonic acid In acetone at 0 - 20℃; for 0.666667h;1.2 g
propylamine
107-10-8

propylamine

pantothenic acid
79-83-4

pantothenic acid

(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-(propylamino)propyl)butanamide
874304-32-2

(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-(propylamino)propyl)butanamide

Conditions
ConditionsYield
Stage #1: pantothenic acid With diphenyl phosphoryl azide; triethylamine In N,N-dimethyl-formamide at 0℃; for 0.333333h; Inert atmosphere;
Stage #2: propylamine In N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere;
79%
pantothenic acid
79-83-4

pantothenic acid

p-Anisaldehyde dimethyl acetal
2186-92-7

p-Anisaldehyde dimethyl acetal

3-{[(4R)-2-(p-methoxyphenyl)-5,5-dimethyl-1,3-dioxan-4-yl]carbonylamino}propionic acid
864239-47-4

3-{[(4R)-2-(p-methoxyphenyl)-5,5-dimethyl-1,3-dioxan-4-yl]carbonylamino}propionic acid

Conditions
ConditionsYield
With camphor-10-sulfonic acid In N,N-dimethyl-formamide at 20℃; for 16h;75%
With camphor-10-sulfonic acid In N,N-dimethyl-formamide68%
With (1S)-10-camphorsulfonic acid In dichloromethane at 20℃;51%
In dichloromethane at 20℃; for 8h;48%
With camphor-10-sulfonic acid In dichloromethane at 20℃;35%
pantothenic acid
79-83-4

pantothenic acid

N-(2-aminoethyl)-3-hydroxy-5,5-dimethoxy-3-methylpentanamide
101759-90-4

N-(2-aminoethyl)-3-hydroxy-5,5-dimethoxy-3-methylpentanamide

N-<3-<<(2,4-dihydroxy-3,3-dimethylbutanoyl)amino>propanamido>ethyl>-3-hydroxy-5,5-dimethoxy-3-methylpentanamide
101759-91-5, 101759-92-6

N-<3-<<(2,4-dihydroxy-3,3-dimethylbutanoyl)amino>propanamido>ethyl>-3-hydroxy-5,5-dimethoxy-3-methylpentanamide

Conditions
ConditionsYield
With 2,2'-dipyridyldisulphide; triphenylphosphine In N,N-dimethyl-formamide for 1h;71%
pantothenic acid
79-83-4

pantothenic acid

2-amino tritylthio ethane
1095-85-8

2-amino tritylthio ethane

S-tritylpantetheine

S-tritylpantetheine

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In acetonitrile at 20℃; for 24h;68%
pantothenic acid
79-83-4

pantothenic acid

2-amino tritylthio ethane
1095-85-8

2-amino tritylthio ethane

S-tritylpantetheine

S-tritylpantetheine

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In acetonitrile at 20℃; for 24h;68%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In acetonitrile at 20℃; for 24h;68%
pantothenic acid
79-83-4

pantothenic acid

p-anisaldehyde-dimethoxy-acetal

p-anisaldehyde-dimethoxy-acetal

3-{[2-(4-Methoxy-phenyl)-5,5-dimethyl-[1,3]dioxane-4-carbonyl]-amino}-propionic acid

3-{[2-(4-Methoxy-phenyl)-5,5-dimethyl-[1,3]dioxane-4-carbonyl]-amino}-propionic acid

Conditions
ConditionsYield
In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran51%
pantothenic acid
79-83-4

pantothenic acid

p-Anisaldehyde dimethyl acetal
2186-92-7

p-Anisaldehyde dimethyl acetal

C17H23NO6

C17H23NO6

Conditions
ConditionsYield
With camphor-10-sulfonic acid at 20℃; for 16h; Inert atmosphere;50%
pantothenic acid
79-83-4

pantothenic acid

thiophenol
108-98-5

thiophenol

S-phenyl thiopantothenate
142611-90-3

S-phenyl thiopantothenate

Conditions
ConditionsYield
With diethyl cyanophosphonate; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 2.16667h;48%
With diphenyl phosphoryl azide; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 3.16667h;42%
pantothenic acid
79-83-4

pantothenic acid

ethanethiol
75-08-1

ethanethiol

ethyl thiopantothenate
521981-75-9

ethyl thiopantothenate

Conditions
ConditionsYield
With diphenylphosphoranyl azide; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 2.33333h;46%
With diphenylphosphoranyl azide; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 2.16667h;32%
(2R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-(3.4-dihydroxy-butylamide)

(2R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-(3.4-dihydroxy-butylamide)

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With barium permanganate; sulfuric acid
D-pantoic acid
1112-33-0

D-pantoic acid

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
unter Einw. von Acetobacter suboxydans;
coenzyme A
85-61-0

coenzyme A

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Hydrolysis.enzymatische Hydrolyse;
L-valine
72-18-4

L-valine

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
Mechanism; multistep reaction; also by using (2RS)-(3S)-4-(13C)-valine; biosynthesis of pantothenic acid; stereospecificity of the biological hydroxymethylation of 2-oxo-isovaleric acid;
(+)(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-lactone

(+)(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-lactone

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
unter Einw. von Acetobacter suboxydans;
benzyl 3-aminopropionate
14529-00-1

benzyl 3-aminopropionate

(-)(R)-pantolactone

(-)(R)-pantolactone

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
at 100℃; Hydrogenolyse des Reaktionsprodukts an Platin in Eisessig oder Ameisensaeure;
pantothenol
81-13-0

pantothenol

sulfuric acid
7664-93-9

sulfuric acid

Ba(MnO4)2

Ba(MnO4)2

pantothenic acid
79-83-4

pantothenic acid

(R)-Pantolacton
599-04-2

(R)-Pantolacton

calcium-<3-amino propionate>

calcium-<3-amino propionate>

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With methanol
(R)-2.4-diacetoxy-3.3-dimethyl-butyric acid-<3-hydroxy-propylamide>

(R)-2.4-diacetoxy-3.3-dimethyl-butyric acid-<3-hydroxy-propylamide>

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With barium permanganate; sulfuric acid anschliessende Hydrolyse mit wss.Ba(OH)2;
(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-<3.3-diethoxy-propylamide>

(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-<3.3-diethoxy-propylamide>

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With dihydrogen peroxide; oxalic acid
(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-<3-oxo-propylamide>

(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid-<3-oxo-propylamide>

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
With barium dihydroxide; silver(l) oxide
sodium β-alaninate
16690-93-0

sodium β-alaninate

(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid amide

(R)-2.4-dihydroxy-3.3-dimethyl-butyric acid amide

pantothenic acid
79-83-4

pantothenic acid

Conditions
ConditionsYield
at 100℃;
oxalic acid
144-62-7

oxalic acid

(R)-N-(3,3-diethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide
851986-98-6

(R)-N-(3,3-diethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide

H2O2

H2O2

water

water

pantothenic acid
79-83-4

pantothenic acid

pantothenic acid
79-83-4

pantothenic acid

dicyclohexyl-carbodiimide
538-75-0

dicyclohexyl-carbodiimide

N-(D-Pantothenoyl)-N,N'-dicyclohexylurea
75980-10-8

N-(D-Pantothenoyl)-N,N'-dicyclohexylurea

Conditions
ConditionsYield
In 1,4-dioxane for 24h;42.3%
pantothenic acid
79-83-4

pantothenic acid

sodium thiomethoxide
5188-07-8

sodium thiomethoxide

methyl thiopantothenate

methyl thiopantothenate

Conditions
ConditionsYield
With diphenylphosphoranyl azide; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 2.16667h;39%
pantothenic acid
79-83-4

pantothenic acid

Propargylamine
2450-71-7

Propargylamine

(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-(prop-2-yn-1-ylamino)propyl)butanamide

(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-(prop-2-yn-1-ylamino)propyl)butanamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide38%
ethanol
64-17-5

ethanol

pantothenic acid
79-83-4

pantothenic acid

ethyl D-pantothenate
10527-68-1

ethyl D-pantothenate

Conditions
ConditionsYield
With hydrogenchloride33%
3-ethylhexane
619-99-8

3-ethylhexane

pantothenic acid
79-83-4

pantothenic acid

[2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid 2-amino-ethyl ester

[2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid 2-amino-ethyl ester

4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran
96042-30-7

4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

[2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid 2-[3-((R)-2,4-dihydroxy-3,3-dimethyl-butyrylamino)-propionylamino]-ethyl ester

[2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid 2-[3-((R)-2,4-dihydroxy-3,3-dimethyl-butyrylamino)-propionylamino]-ethyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; triethylamine In methanol; N,N-dimethyl-formamide26.4%
pantothenic acid
79-83-4

pantothenic acid

(2-aminoethyl)methylsulfide
18542-42-2

(2-aminoethyl)methylsulfide

(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-((2-(methylthio)ethyl)amino)-3-oxopropyl)butanamide

(R)-2,4-dihydroxy-3,3-dimethyl-N-(3-((2-(methylthio)ethyl)amino)-3-oxopropyl)butanamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 25℃; for 2h;21.02%
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