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Antimex Chemical Limied

Quick Details ProName: Hot sale 2016 New Anti-Early Pregnancy... CasNo: 84371-65-3 Molecular Formula: C29H35NO2 Appearance: white or off white crystalline powder Application: A reversible serine protease blocking ..

Mifepristone

Cas:84371-65-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Luyunjia Chemistry Xiamen Limited

Xiamen Luyunjia Trading Co.,Ltd Package:1kg/bag; 3902kg/drum, or as customer's request. Application:Xiamen Luyunjia Trading Co.,Ltd Transportation:DHL, EMS, FedEx, TNT, AIR, SEA Port:Beijing,Shanghai,Guangzhou ,China main port

Mifepristone

Cas:84371-65-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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HANWAYS CHEMPHARM CO.,LIMITED

We are concentrating on APIs and pharmaceutical intermediates. With in depth knowledge and understanding in this industry, we are indulged in supplying a wide assortments of Mifepristone from Wuhan, Hubei, China. It is made obtainable from us a

GMP Factory Supply Mifepristone CAS 84371-65-3

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $4.8 / 5.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Mifepristone Manufacturer/High quality/Best price/In stock

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

----------------------------------------------------------------------- Hangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chem

High purity Mifepristone with high quality cas:84371-65-3

Cas:84371-65-3

Min.Order:1 Gram

FOB Price: $1100.0 / 1300.0

Type:Manufacturers

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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF Mifepristone 84371-65-3

Cas:84371-65-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

Name: Mifepristone Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-… Founded in 2014, as a professional international pharmaceutical corporation, headquarter

Mifepristone

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Other

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu

Mifepristone 84371-65-3 API

Cas:84371-65-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Mifepristone CAS NO.84371-65-3

Cas:84371-65-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Light yellowish crystalline powder Storage:2-8°C Package:1kg/

Favorable price Mifepristone CAS 84371-65-3 supplied by manufacturer

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

Mifepristone CAS No.:84371-65-3 Name: Mifepristone Synonyms: 11b-[p-(Dimethylamino)phenyl]-17b-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one Molecular Structure Molecular Formula: C29H35NO

High purity Mifepristone CAS No.:84371-65-3

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Mifepristone

Cas:84371-65-3

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Mifepristone 84371-65-3 ISO Producer

Cas:84371-65-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Mifepristone

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Mifepristone -- CHemwill

Cas:84371-65-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Hubei Vanz Pharm Co.,Ltd

Hubei Vanz Pharm Co. Ltd. is located in Wuhan, Hubei province. We export to many countries and area with very competitive price, high quality, good service. Excellent capacity to support your business. Fast delivery. We also have our own reasearch

Mifepristone CAS 84371-65-3 high quality

Cas:84371-65-3

Min.Order:1 Gram

FOB Price: $10.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Mifeprestone The alias:ra-4,9-dien-3-one;ru486-6;MIFEGYNE;MIFEPRISTONE;RU-38486;RU486 CAS NO:84371-65-3 EINECS NO:617-559-7 Molecular formula:C29H35NO2 Molecular weight:429.6 Product Quality 12 years of chemical raw materials Mature

Mifeprestone/CAS:84371-65-3/with favorable price

Cas:84371-65-3

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM Mifepristone

Cas:84371-65-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Mifepristone/ LIDE PHARMA- Factory supply / Best price

Cas:84371-65-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Mifepristone

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 84371-65-3 with best quality

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Purestar Chem Enterprise Co.,Ltd

Mifepristone Products Name : Mifepristone CAS No. : 84371-65-3 Structural Formula : Molecular formula : 1kg/tin 5kg/tin Mol

Mifepristone

Cas:84371-65-3

Min.Order:25 Kilogram

FOB Price: $6.0

Type:Trading Company

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:pale yellow solid Storage:Room temperature Package:1kg/bag Application:API Transportation:Express/Sea/Air Port:Any port in china

Manufacture Mifepristone CAS:84371-65-3 RU-486 Mifepristone Chinese Supplier

Cas:84371-65-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 84371-65-3 Mifepristone with best price

Cas:84371-65-3

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Mifepristone 84371-65-3

Cas:84371-65-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Anti-pregnancy, Mifepristone CAS:84371-65-3

Cas:84371-65-3

Min.Order:1 Gram

FOB Price: $21.0 / 24.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality Mifepristone CAS 84371-65-3 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in China an

High quality Mifepristone CAS 84371-65-3

Cas:84371-65-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

Our advantages: Advantage 1, we have overseas warehouse in the local country Products can be shipped to you from overseas warehouse. 3-4 days safe delivery. Or you can go to the warehouse and pick it up. (This can be selected according to the produc

Mifepristone manufacturer with low price CAS 84371-65-3

Cas:84371-65-3

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Mifepristone

Cas:84371-65-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

mifepristone
84371-65-3

mifepristone

aglepristone

aglepristone

Conditions
ConditionsYield
With hydrogen In methanol under 3800.26 Torr; Reagent/catalyst; Solvent; Green chemistry; stereoselective reaction;99%
2-Picolinic acid
98-98-6

2-Picolinic acid

mifepristone
84371-65-3

mifepristone

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylpicolinamide

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylpicolinamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;98%
tri-n-butyl-tin hydride
688-73-3

tri-n-butyl-tin hydride

mifepristone
84371-65-3

mifepristone

C41H63NO2Sn

C41H63NO2Sn

Conditions
ConditionsYield
With [MoI2(CO)2(CNC6H3(C6H3iPr2-2,6)2-2,6)2] In benzene-d6 at 20℃; for 0.5h; Inert atmosphere; Schlenk technique; Glovebox;98%
mifepristone
84371-65-3

mifepristone

Demethylmifepristone
104004-96-8

Demethylmifepristone

Conditions
ConditionsYield
With lithium acetate; iodine In tetrahydrofuran; methanol at 0 - 20℃; for 24h; Reagent/catalyst; Temperature; Solvent;97%
With lithium acetate; iodine In tetrahydrofuran; methanol at 20℃;92%
With iodine; calcium oxide In tetrahydrofuran; methanol at 0℃; for 1h;82%
mifepristone
84371-65-3

mifepristone

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-chloro-N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylacetamide

2-chloro-N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylacetamide

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 0 - 20℃; for 16h;92%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

methyl (3β,5β,7α,12α)-7,12-dixydroxy-3-(2-hydroxyethoxy)cholan-24-oate
135053-66-6

methyl (3β,5β,7α,12α)-7,12-dixydroxy-3-(2-hydroxyethoxy)cholan-24-oate

mifepristone
84371-65-3

mifepristone

methyl (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate
639520-78-8

methyl (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate

Conditions
ConditionsYield
Stage #1: trifluoromethylsulfonic anhydride; methyl (3β,5β,7α,12α)-7,12-dixydroxy-3-(2-hydroxyethoxy)cholan-24-oate With N-ethyl-N,N-diisopropylamine In dichloromethane at -55 - -45℃; for 3.28333h;
Stage #2: mifepristone In dichloromethane at -6℃; for 88h;
Stage #3: With N-ethyl-N,N-diisopropylamine; sodium iodide In acetonitrile for 45h; Heating / reflux;
82.7%
mifepristone
84371-65-3

mifepristone

benzoic acid
65-85-0

benzoic acid

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylbenzamide

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylbenzamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;77%
4'-Hydroxybiphenyl-4-carboxylic acid
58574-03-1

4'-Hydroxybiphenyl-4-carboxylic acid

mifepristone
84371-65-3

mifepristone

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methyl-[1,1'-biphenyl]-4-carboxamide

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methyl-[1,1'-biphenyl]-4-carboxamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;73%
3,4-dichlorbenzoic acid
51-44-5

3,4-dichlorbenzoic acid

mifepristone
84371-65-3

mifepristone

3,4-dichloro-N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylbenzamide

3,4-dichloro-N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylbenzamide

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;71%
triphenylboroxine
3262-89-3

triphenylboroxine

mifepristone
84371-65-3

mifepristone

(8S,11R,13S,14S)-11-(4-(dimethylamino)phenyl)-13-methyl-17-((S)-2-phenylprop-1-en-1-ylidene)-6,7,8,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

(8S,11R,13S,14S)-11-(4-(dimethylamino)phenyl)-13-methyl-17-((S)-2-phenylprop-1-en-1-ylidene)-6,7,8,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Conditions
ConditionsYield
With [Rh(OH)(cod)]2 In tetrahydrofuran at 75℃; for 12h; Inert atmosphere; diastereoselective reaction;69%
4-trifluoromethylphenylboronic acid
128796-39-4

4-trifluoromethylphenylboronic acid

mifepristone
84371-65-3

mifepristone

(8S,11R,13S,14S,17R)-11-(4-(dimethylamino)phenyl)-17-hydroxy-13-methyl-17-((E)-2-(4-(trifluoromethyl)phenyl)prop-1-en-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

(8S,11R,13S,14S,17R)-11-(4-(dimethylamino)phenyl)-17-hydroxy-13-methyl-17-((E)-2-(4-(trifluoromethyl)phenyl)prop-1-en-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With water; 8CO*2Br(1-)*2Mn(1+); potassium hydrogencarbonate In toluene; pentane at 90℃; for 0.25h; Sealed tube; regioselective reaction;68%
2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

mifepristone
84371-65-3

mifepristone

(8S,11R,13S,14S,17S)-11-(4-((2-chlorophenyl)(methyl)amino)phenyl)-17-hydroxy-13-methyl-17-(prop-1-yn-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

(8S,11R,13S,14S,17S)-11-(4-((2-chlorophenyl)(methyl)amino)phenyl)-17-hydroxy-13-methyl-17-(prop-1-yn-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With tetrachloromethane; potassium fluoride; 18-crown-6 ether In tetrahydrofuran at 65℃; for 10h; Sealed tube;67%
mifepristone
84371-65-3

mifepristone

A

Demethylmifepristone
104004-96-8

Demethylmifepristone

B

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylformamide
639520-83-5

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylformamide

Conditions
ConditionsYield
Stage #1: mifepristone With 1,4-diaza-bicyclo[2.2.2]octane; rose bengal; acetic acid In acetonitrile at 20℃; for 1.5h; Flow reactor; Irradiation;
Stage #2: With ascorbic acid In water; acetonitrile at 20℃; for 2h;
A 65%
B 22%
mifepristone
84371-65-3

mifepristone

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylformamide
639520-83-5

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylformamide

Conditions
ConditionsYield
With N-methyl-2-indolinone; tetrapropylammonium perruthennate In dichloromethane at 0℃; for 0.333333h;63%
Stage #1: mifepristone With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide In dichloromethane at -10℃;
Stage #2: With sodium disulfite In dichloromethane; water at -10 - 20℃; for 0.5h;
63%
N-phenyl-maleimide
941-69-5

N-phenyl-maleimide

mifepristone
84371-65-3

mifepristone

(3aR*,9bS*)-8-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-5-methyl-2-phenyl-3a,4,5,9b-tetrahydro-1H-pyrrolo[3,4-c]quinoline-1,3(2H)-dione

(3aR*,9bS*)-8-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-5-methyl-2-phenyl-3a,4,5,9b-tetrahydro-1H-pyrrolo[3,4-c]quinoline-1,3(2H)-dione

Conditions
ConditionsYield
With chloropyridinecobaloxime(III); Ru(bpy)3Cl2*6H2O In acetonitrile at 20℃; for 24h; Inert atmosphere; Irradiation;62%
mifepristone
84371-65-3

mifepristone

4-chloro-2-fluorobenzoic acid
446-30-0

4-chloro-2-fluorobenzoic acid

5-chloro-2-fluoro-N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylbenzamide

5-chloro-2-fluoro-N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylbenzamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 30h;61%
methyl (3β,5β,7α,12α)-7,12-dihydroxy-3-[2-(iodo)ethoxy]cholan-24-oate
639520-81-3

methyl (3β,5β,7α,12α)-7,12-dihydroxy-3-[2-(iodo)ethoxy]cholan-24-oate

mifepristone
84371-65-3

mifepristone

methyl (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate
639520-78-8

methyl (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 80℃; for 19h;60.6%
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

mifepristone
84371-65-3

mifepristone

C33H40N4O4

C33H40N4O4

Conditions
ConditionsYield
With 1-hydroxy-1,2-benzodioxol-3-(1H)-one; trimethylsilylazide In acetonitrile at 20℃; Inert atmosphere; chemoselective reaction;54%
mifepristone
84371-65-3

mifepristone

C29H33NO2
1356033-06-1

C29H33NO2

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetic acid at 20℃; for 1h; Sonication;41%
mifepristone
84371-65-3

mifepristone

C29H32Cl3NO2
1356033-08-3

C29H32Cl3NO2

Conditions
ConditionsYield
With 1,3,5-trichloro-2,4,6-triazine In acetonitrile at 20℃; for 48h;41%
3-iodo-N-((5-methylfuran-2-yl)methyl)propanamide

3-iodo-N-((5-methylfuran-2-yl)methyl)propanamide

mifepristone
84371-65-3

mifepristone

C37H44N2O4

C37H44N2O4

Conditions
ConditionsYield
In acetonitrile at 120℃; for 2h; Microwave irradiation;40%
ethyl 4-iodobutyrate
7425-53-8

ethyl 4-iodobutyrate

mifepristone
84371-65-3

mifepristone

C34H43NO4

C34H43NO4

Conditions
ConditionsYield
In acetonitrile at 120℃; for 1h; Microwave irradiation;36%
mifepristone
84371-65-3

mifepristone

A

6α-hydroxy-mifepristone

6α-hydroxy-mifepristone

B

6β-hydroxy-mifepristone

6β-hydroxy-mifepristone

Conditions
ConditionsYield
With selenium(IV) oxide In 1,4-dioxane at 80℃; for 20h;A 4%
B 35%
mifepristone
84371-65-3

mifepristone

C28H33NO5
1356033-03-8

C28H33NO5

Conditions
ConditionsYield
With dihydrogen peroxide In dichloroethane at 20℃; for 4h;32%
mifepristone
84371-65-3

mifepristone

C28H31NO3
1356033-05-0

C28H31NO3

Conditions
ConditionsYield
With Cumene hydroperoxide; C44H24FeN8O8 In dichloroethane at 20℃; for 6h;19%
mifepristone
84371-65-3

mifepristone

(8S,11R,13S,14S,17S)-11-(3,5-dichloro-4-(dimethylamino)phenyl)-17-hydroxy-13-methyl-17-(prop-1-yn-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

(8S,11R,13S,14S,17S)-11-(3,5-dichloro-4-(dimethylamino)phenyl)-17-hydroxy-13-methyl-17-(prop-1-yn-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With trichloroisocyanuric acid In dichloromethane at 20℃; for 15h;18%
mifepristone
84371-65-3

mifepristone

A

<5R,7Ξ,8R,8aR>-5-<4-(dimethylamino)phenyl>-4,5,6,7,8,8a,9,10-octahydro-7-methyl-8-(3-oxo-4-hexinyl)-2(3H)-phenanthrenone

<5R,7Ξ,8R,8aR>-5-<4-(dimethylamino)phenyl>-4,5,6,7,8,8a,9,10-octahydro-7-methyl-8-(3-oxo-4-hexinyl)-2(3H)-phenanthrenone

B

Demethylmifepristone
104004-96-8

Demethylmifepristone

Conditions
ConditionsYield
for 336h; Irradiation; photodecomposition in crystalline state; other times;A 0.2%
B 0.5%
for 336h; Irradiation;A 0.2%
B 0.5%
mifepristone
84371-65-3

mifepristone

O-(6-aminohexyl)hydroxylamine

O-(6-aminohexyl)hydroxylamine

A

11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one syn-O-(6-aminohexyl)oxime

11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one syn-O-(6-aminohexyl)oxime

B

11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one anti-O-(6-aminohexyl)oxime

11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one anti-O-(6-aminohexyl)oxime

Conditions
ConditionsYield
In ethanol at 20℃; for 2h; Title compound not separated from byproducts;
mifepristone
84371-65-3

mifepristone

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylacetamide

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylacetamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 63 percent / NMO; tetra-n-propylammonium perruthenate / CH2Cl2 / 0.33 h / 0 °C
2: 86 percent / aq. HCl / methanol / 40 h / 20 °C
3: pyridine / 2 h / 60 °C
View Scheme
Multi-step reaction with 2 steps
1: lithium acetate; iodine / tetrahydrofuran; methanol / 20 °C
2: triethylamine / ethyl acetate / 16 h / 0 - 20 °C / Inert atmosphere
View Scheme
mifepristone
84371-65-3

mifepristone

(S)-2-Amino-4-{[4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl]-methyl-carbamoyl}-butyric acid methyl ester
734523-73-0

(S)-2-Amino-4-{[4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl]-methyl-carbamoyl}-butyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 63 percent / NMO; tetra-n-propylammonium perruthenate / CH2Cl2 / 0.33 h / 0 °C
2: 86 percent / aq. HCl / methanol / 40 h / 20 °C
3: 0.93 g / TBTU; diisopropylethylamine / dimethylformamide / 48 h / 20 °C
4: HCl / ethyl acetate / 1 h
View Scheme

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