13505-32-3

Basic information

• Product Name: N-(P-TOLUENESULFONYL)-L-PHENYLALANINE
• Synonyms: TOSYL-L-PHENYLALANINE;TOS-PHENYLALANINE-OH;TOS-PHE-OH;P-TOSYL-L-PHENYLALANINE;N-TOSYL-L-PHENYLALANINE;N-P-TOSYL-L-PHENYLALANINE;N-(P-TOLUENESULFONYL)-L-PHENYLALANINE;N-P-TOSYL-L-PHENYLALANINE 97%
• CAS NO: 13505-32-3
• Molecular Formula: C₁₆H₁₇NO₄S
• Molecular Weight: 319.38
• EINECS: 1533716-785-6
• Product Categories: Amino Acid Derivatives;Amino Acids
• Mol File: 13505-32-3.mol
• Article Data: 57

Chemical Properties

• Melting Point: 165 °C
• Boiling Point: 517.7°Cat760mmHg
• Flash Point: 266.9°C
• Appearance: /
• Density: 1.303g/cm³
• Vapor Pressure: 1.52E-11mmHg at 25°C
• Refractive Index: -2.8 ° (C=4.5, Acetone)
• Storage Temp.: Store at RT.
• Solubility: almost transparency in hot EtOH
• PKA: 3.31±0.10(Predicted)
• CAS DataBase Reference: N-(P-TOLUENESULFONYL)-L-PHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(P-TOLUENESULFONYL)-L-PHENYLALANINE(13505-32-3)
• EPA Substance Registry System: N-(P-TOLUENESULFONYL)-L-PHENYLALANINE(13505-32-3)

Safety Data

• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 13505-32-3(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white solid

InChI:InChI=1/C16H17NO4S/c1-12-7-9-14(10-8-12)22(20,21)17-15(16(18)19)11-13-5-3-2-4-6-13/h2-10,15,17H,11H2,1H3,(H,18,19)

Upstream product

• 818-72-4 1-Octyn-3-ol 
• 90365-18-7 N-(p-toluenesulfonyl)-L-phenylalanyl chloride 
• 88955-90-2 7-(N-tosyl-L-phenylalanyl)amino-4-nitrobenzo-2-oxa-1,3-diazole 
• 63-91-2 L-phenylalanine 
• 98-59-9 p-toluenesulfonyl chloride 
• 88452-86-2 (2S)-N-para-toluenesulfonylaziridine-2-carboxylic acid 
• 918886-05-2 N-(p-toluenesulfonyl) phenylalanine (9-methoxy-3-oxo-3H-benzo[f]benzopyran-1-yl) methyl ester 
• 591-51-5 phenyllithium 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 90365-18-7 N-(p-toluenesulfonyl)-L-phenylalanyl chloride 
• 90303-21-2 (S)-3-Phenyl-N-pyrimidin-2-yl-2-(toluene-4-sulfonylamino)-propionamide 
• 63-91-2 L-phenylalanine 
• 673-06-3 D-(R)-phenylalanine 
• 82495-70-3 (2S)-2-p-toluenesulfonamido-3-phenylpropanol 
• 82495-71-4 (2S)-2-(N-benzyl-p-toluenesulfonamido)-3-phenylpropionic acid benzyl ester 
• 150062-18-3 (S)-4-methyl-N-(1-oxo-1,3-diphenylpropan-2-yl)benzenesulfonamide 
• 127597-94-8 (3S)-4-Phenyl-3-(N-(p-toluenesulfonyl)amino)-2-butanone 
• 67850-39-9 N-p-Toluolsulfonyl-L-phenylalanin-benzylester 
• 612-94-2 2-phenylnaphthalene 
• 17024-58-7 (E)-2,4,6-trimethylstilbene 
• 5184-64-5 1,3,5-trimethyl-2-(toluene-4-sulfonyl)-benzene 
• 206268-34-0 1-N-tert-butyloxycarbonyl-4-N-methyl-4-N-(α-N-tosylphenylalanyl)-(1,4)-diaminobutan-2-ol 

Relevant articles and documents

Synthesis, characterization and cytotoxicity of platinum(II)/palladium(II) complexes with 1,3-diaminopropane and 4-toluensulfonyl-l-amino acid dianion

Eight novel platinum(II)/palladium(II) complexes with 1,3-dap and 4-toluensulfonyl-l-amino acid dianion, [Pt(1,3-dap)(TsalaNO)]·0.5H 2O (1a), [Pt(1,3-dap)(TsvalNO)] (1b), [Pt(1,3-dap)(TspheNO)] (1c), [Pt(1,3-dap)(TsserNO)] (1d), [Pd(1,3-dap)(Ts

Synthesis and Structural Characterization of Trivalent Amino Acid Derived Chiral Phosphorus Compounds

Reaction of the N-toluenesulfonyl derivatives of (S)-alanine, phenylalanine, and valine (4-6) with PhPCl2 gave in high yield the 4-methyl, benzyl, and isopropyl derivatives (7-9) of 2-phenyl-1-p-toluenesulfonyl-1,3,2-oxazaphospholidin-5-one. Th

Synthesis, characterization and cytotoxicity of mixed-ligand complexes of palladium(II) with 2, 2′-biquinoline/1, 4-diaminobutane and 4-toluenesulfonyl-L-amino acid dianion

Seven new palladium(II) complexes (1-7) with 4-toluenesulfonyl-L-amino acid dianion and 2, 2′-biquinoline (bqu)/1,4-diaminobutane (dab) have been synthesized and characterized by elemental analysis, IR, 1H NMR, and mass spectra techniques. Crys

Synthesis and hetero-Diels-Alder reactions of enantiomerically pure dihydro-1: H -azepines

Thermolysis of enantiomerically pure 3-substituted 7,7-dihalo-2-azabicyclo[4.1.0]heptanes in the presence of K2CO3 gives in good yields 2-alkyl-6-halo-1-tosyl-2,3-dihydro-1H-azepines. These undergo highly stereoselective [4+2] cycloaddition reactions with heterodienophiles and arylation/alkenylation under Suzuki conditions.

Synthesis, Characterization, and Reactivity of an Ethynyl Benziodoxolone (EBX)-Acetonitrile Complex

The synthesis of a crystalline ethynyl-1,2-benziodoxol-3(1H)-one (EBX)-acetonitrile complex is described. EBX has been widely used as an active species for a variety of reactions; however, its high instability has so far prevented its isolation. The EBX-acetonitrile is self-assembled into a double-layered honeycomb structure through weak hypervalent iodine secondary interactions and hydrogen bonding. The N-ethynylation of a variety of sulfonamides using the EBX-acetonitrile complex as a substrate under mild conditions is also described.