13737-36-5 Usage
Description
4-(Bromomethyl)phenylacetic acid is a white to light beige crystalline powder with chemical properties that make it a versatile compound in various applications. It is an organic compound that belongs to the class of phenylacetic acids, characterized by the presence of a bromomethyl group attached to the 4-position of the phenyl ring.
Uses
Used in Pharmaceutical Industry:
4-(Bromomethyl)phenylacetic acid is used as a precursor for the synthesis of serine protease inhibitors, which are important in the development of drugs targeting various diseases, including cancer and inflammatory conditions. Its unique chemical structure allows for the creation of specific inhibitors that can selectively target and regulate the activity of serine proteases.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-(Bromomethyl)phenylacetic acid serves as a key intermediate for the production of various compounds, such as novel crown ether receptors and 4-(acetoxymethyl)phenylacetic acid. By reacting with excessive sodium acetate and acetic acid, it can be further modified to create new molecules with potential applications in different industries.
Used in Research and Development:
4-(Bromomethyl)phenylacetic acid is also utilized in research and development for the exploration of its chemical properties and potential applications in various fields. Its unique structure and reactivity make it an interesting candidate for the development of new compounds and materials with specific functions and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 13737-36-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,3 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 13737-36:
(7*1)+(6*3)+(5*7)+(4*3)+(3*7)+(2*3)+(1*6)=105
105 % 10 = 5
So 13737-36-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H9BrO2/c10-6-8-3-1-7(2-4-8)5-9(11)12/h1-4H,5-6H2,(H,11,12)
13737-36-5Relevant articles and documents
Synthesis of α-Helices Having a Positively Charged Random Coil-Block on Either N- or C-Terminal
Takahashi, Sho,Hibino, Takeshi,Sawada, Seiji
, p. 2467 - 2472 (1988)
To study a charge-induced stabilization of α-helix, α-helical peptides having a positively charged random-coil block on either N- or C-terminal of the helix, and having a strictly defined length, (Ala)20(X)20Phe and (X)20(Ala)20Phe(X=Lys or Orn), were syn
Preparation method of netarsudil mesylate
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Paragraph 0021, (2021/07/17)
The invention relates to a preparation method of netarsudil mesylate.Netarsudil mesylate is synthesized by utilizing chiral induction, and compared with an existing chiral HPLC method or SFC method, netarsudil mesylate prepared by adopting a chemical synt
BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME
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Paragraph 0173, (2019/05/10)
The present invention discloses a biaryl urea RORγt inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an RORγt inhibiting activity, and a preparation process thereof, and a pharmaceutical composition comprising the compound. Further disclosed is use of the compound for treating an RORγt-related disease.