2248-13-7

Basic information

• Product Name: 4-(4-FLUOROPHENYL)-1-BUTENE
• Synonyms: TIMTEC-BB SBB008824;4-(4-FLUOROPHENYL)-1-BUTENE;4-(4-Fluorophenyl)but-1-ene;4-(4-Fluorophenyl)but-1-ene, 1-(But-3-en-1-yl)-4-fluorobenzene;4-(But-3-en-1-yl)fluorobenzene;1-(But-3-en-1-yl)-4-fluorobenzene;4-(4-Fluorophenyl)but-1-ene, 1-Fluoro-4-homoallylbenzene
• CAS NO: 2248-13-7
• Molecular Formula: C₁₀H₁₁F
• Molecular Weight: 150.19
• Mol File: 2248-13-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 72/9mm
• Flash Point: 56.1 °C
• Appearance: /
• Density: 0.97
• Vapor Pressure: 1.09mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: 4-(4-FLUOROPHENYL)-1-BUTENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-FLUOROPHENYL)-1-BUTENE(2248-13-7)
• EPA Substance Registry System: 4-(4-FLUOROPHENYL)-1-BUTENE(2248-13-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 2248-13-7(Hazardous Substances Data)

Usage

General Description

4-(4-Fluorophenyl)-1-butene is a chemical compound with the molecular formula C10H11F. Its chemical structure consists of a butene backbone with a fluorophenyl group attached to the fourth carbon. 4-(4-FLUOROPHENYL)-1-BUTENE is used in organic synthesis and research, and its properties make it suitable for use in the production of various organic compounds. It is important to handle this chemical with care, as it is flammable and may cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Additionally, it may have potential environmental and health hazards, so proper precautions and safety measures should be taken when using or handling this compound.

InChI:InChI=1/C10H11F/c1-2-3-4-9-5-7-10(11)8-6-9/h2,5-8H,1,3-4H2

Upstream product

• 106-95-6 allyl bromide 
• 84648-52-2 C₁₈H₁₆ClFO₄ 
• 106-99-0 buta-1,3-diene 
• 352-13-6 4-flourophenylmagnesium bromide 
• 2622-05-1 allylmagnesium bromide 
• 459-46-1 4-Fluorobenzyl bromide 
• 1730-25-2 allylmagnesium bromide 
• 459-57-4 4-fluorobenzaldehyde 
• 591-87-7 Allyl acetate 
• 401514-49-6 [(4-fluorophenyl)methylidene]hydrazine 
• 459-51-8 1-fluoro-4-(fluoromethyl)benzene 
• 762-72-1 allyl-trimethyl-silane 
• 459-31-4 3-(4-fluorophenyl)propanoic acid 
• 702-15-8 3-(4-fluorophenyl)propan-1-ol 

Downstream Products

• 109635-75-8 [4-(4-fluorophenyl)butyl]phosphinic acid 
• 111496-58-3 (S)-1-((S)-6-Benzyloxycarbonylamino-2-{[4-(4-fluoro-phenyl)-butyl]-hydroxy-phosphinoyloxy}-hexanoyl)-pyrrolidine-2-carboxylic acid benzyl ester 
• 1214320-52-1 (Z)-triethyl(4-(4-fluorophenyl)but-1-enyl)silane 
• 1214320-65-6 (E)-triethyl(4-(4-fluorophenyl)but-1-enyl)silane 
• 1267588-86-2 C₂₄H₂₀FNO₃S 
• 1267588-73-7 C₂₄H₂₀FNO₃S 
• 65300-29-0 4-(4-fluorophenyl)but-3-en-2-one 
• 20651-65-4 4-(n-butyl)fluorobenzene 
• 24484-22-8 5-(4-fluorophenyl)-pentanoic acid 
• 123494-30-4 1-[(E)-(but-1-en-1-yl)]-4-fluorobenzene 
• 222640-88-2 1-(but-2-en-1-yl)-4-fluorobenzene 
• 222640-88-2 1-(but-2-en-1-yl)-4-fluorobenzene 

Relevant articles and documents

Access to Trisubstituted Fluoroalkenes by Ruthenium-Catalyzed Cross-Metathesis

Although the olefin metathesis reaction is a well-known and powerful strategy to get alkenes, this reaction remained highly challenging with fluororalkenes, especially the Cross-Metathesis (CM) process. Our thought was to find an easy accessible, convenient, reactive and post-functionalizable source of fluoroalkene, that we found as the methyl 2-fluoroacrylate. We reported herein the efficient ruthenium-catalyzed CM reaction of various terminal and internal alkenes with methyl 2-fluoroacrylate giving access, for the first time, to trisubstituted fluoroalkenes stereoselectively. Unprecedent TON for CM involving fluoroalkene, up to 175, have been obtained and the reaction proved to be tolerant and effective with a large range of olefin partners giving fair to high yields in metathesis products. (Figure presented.).

Phosphorus Coordination Chemistry in Catalysis: Air Stable P(III)-Dications as Lewis Acid Catalysts for the Allylation of C-F Bonds

Modification of C-F bonds with main-group catalysts has typically employed electron-deficient Lewis superacids in high oxidation states, and the challenges of preparing and handling such species have prevented broader adoption of metal-free reduction protocols. Here, we show that a hemilabile ligand coordinated to an easily accessed P(III) center imparts air stability without sacrificing the ability to activate C-F bonds. Catalytic C-C coupling of benzyl fluorides with allylsilanes was achieved using a P(III) complex under benchtop conditions. This application of coordination chemistry principles to main-group Lewis acids reveals a new strategy for controlling catalysis.

Palladium-Catalyzed Electrochemical Allylic Alkylation between Alkyl and Allylic Halides in Aqueous Solution

A new route for the direct cross-coupling of alkyl and allylic halides using electrochemical technique has been developed in aqueous media under air. Catalyzed by Pd(OAc)2, the Zn-mediated allylic alkylations proceed smoothly between a full range of alkyl halides (primary, secondary, and tertiary) and substituted allylic halides. Protection-deprotection of acidic hydrogen in the substrates is avoided.