(4-Methoxyphenyl)acetaldehyde supplier

Name
4-METHOXYPHENYLACETALDEHYDE
EINECS 227-191-5
CAS No. 5703-26-4
Article Data193
CAS DataBase
Density 1.045 g/cm³
Solubility Slightly soluble in ethanol
Melting Point 0 °C
Formula C₉H₁₀O₂
Boiling Point 255.5 °C at 760 mmHg
Molecular Weight 150.177
Flash Point 108.5 °C
Transport Information
Appearance Pale yellow clear liquid
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Acetaldehyde,(p-methoxyphenyl)- (7CI,8CI);(p-Methoxyphenyl)acetaldehyde;2-(4-Methoxyphenyl)acetaldehyde;2-(4-Methoxyphenyl)ethanal;2-(p-Anisyl)ethanal;4-Methoxybenzeneacetaldehyde;4-Methoxyphenylacetaldehyde;Homoanisaldehyde;p-Anisylacetaldehyde;
PSA 26.30000
LogP 1.43660

Synthetic route

: 80743-36-8
4-[(E)-2-(4-Methoxy-phenyl)-vinyl]-morpholine

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With aq. acid for 1h; Ambient temperature;	100%

: 23786-14-3
4-methoxy-phenyl acetic acid methyl ester

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With diisobutylaluminium hydride In toluene at -78℃; for 1.16667 - 1.25h;	100%
With diisobutylaluminium hydride In toluene at -70℃; for 0.5h;	81%
With diisobutylaluminium hydride In dichloromethane; toluene at -78℃; for 1.5h; Inert atmosphere;	80%

: 702-23-8
2-(4-Methoxyphenyl)ethanol

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With Dess-Martin periodane In dichloromethane at 0 - 20℃; for 1h;	100%
With Dess-Martin periodane In dichloromethane at 0 - 20℃; for 1h;	100%
With Dess-Martin periodane In dichloromethane at 0 - 20℃; for 1h;	100%

: 140-67-0
Estragole

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With 2,6-dimethylpyridine; osmium(VIII) oxide; [bis(acetoxy)iodo]benzene; water In tetrahydrofuran at 25℃; for 8h; Inert atmosphere;	97%
Stage #1: Estragole With ozone In dichloromethane at -78℃; Stage #2: With (Z,Z,Z)-4,4'-bis[4-(diphenylphosphino)styryl]stilbene In dichloromethane at -78 - 23℃; for 0.5h; Stage #3: With erythrosine B In tetrahydrofuran for 1h; Irradiation;	91%
bei der Ozonspaltung;

: 1-azido-2-(4-methoxyphenyl)propan-2-ol

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With bis[dicarbonylcyclopentadienylruthenium(I)] In tetrahydrofuran-d8 at 20℃; Inert atmosphere; Irradiation;	97%

: 6388-72-3
2-(4-methoxyphenyl)oxirane

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With sodium tetrahydroborate In benzene at 45℃; for 2.5h;	96%
With indium(III) chloride In tetrahydrofuran at 25℃; for 0.166667h; Rearrangement;	90%
With oxovanadium(V) ethoxydichloride In ethanol at 20℃; for 4h; Rearrangement;	90%

: 55-81-2
4-Methoxyphenethylamine

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With Halomonas elongata/Co imm pyridoxal phosphate In toluene at 37℃; for 0.25h; pH=7.5; Flow reactor; Enzymatic reaction;	95%

: S-ethyl 2-(4-methoxyphenyl)ethanethioate

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With triethylsilane; palladium on activated charcoal In tetrahydrofuran at 20℃; for 2h; Fukuyama reduction;	93%

: 101565-19-9
(E/Z)-1-methoxy-4-(2-methoxyvinyl)benzene

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With oxalyl dichloride In ethanol; chloroform; water at 20℃; for 1h;	93%
With formic acid In dichloromethane for 16h; Reflux;	85%
With trifluoroacetic acid In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;	66%

: 105-13-5
4-Methoxybenzyl alcohol

: 75-05-8
acetonitrile

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With C48H36Cl4N8Zn2(2+)*2Cl(1-); oxygen at 20℃; for 4h; Reagent/catalyst; Irradiation;	90.7%

: 637-69-4
4-Methoxystyrene

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With Pyridine-2,6-dicarboxylic acid; iron(II) tetrafluoroborate hexahydrate; iodosylbenzene In chloroform at 20℃; for 20h; Molecular sieve; regioselective reaction;	90%
With ammonium persulfate; Pd(E-2-(benzylthio)-N-{(2-methoxynaphthalene-1-yl)methylene}benzenamine)Cl; 1-butyl-3-methylimidazolium Tetrafluoroborate In water at 70℃; for 0.25h; Wacker Oxidation; Microwave irradiation; regioselective reaction;	85%
With iodosylbenzene; 5,5'-dinitro-N,N'-ethylenebis(salicylideneaminato) manganese(III)(hexafluorophosphate) In acetonitrile at 25℃;	48%

: 60-29-7
diethyl ether

: 23786-14-3
4-methoxy-phenyl acetic acid methyl ester

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With diisobutylaluminium hydride; sodium hydrogencarbonate In toluene	90%

: 4009-98-7
(methoxymethyl)triphenylphosphonium chloride

: 123-11-5
4-methoxy-benzaldehyde

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
Stage #1: (methoxymethyl)triphenylphosphonium chloride; 4-methoxy-benzaldehyde With lithium hexamethyldisilazane In tetrahydrofuran Wittig Olefination; Stage #2: With hydrogenchloride In tetrahydrofuran; water Reflux;	90%
Stage #1: (methoxymethyl)triphenylphosphonium chloride With sodium hexamethyldisilazane In tetrahydrofuran at 0℃; for 0.5h; Stage #2: 4-methoxy-benzaldehyde In tetrahydrofuran at 0 - 20℃; for 2h; Stage #3: With water; toluene-4-sulfonic acid In acetonitrile at 0 - 20℃; for 6h;	53%

: 637-69-4
4-Methoxystyrene

: 2712-78-9
bis-[(trifluoroacetoxy)iodo]benzene

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
Stage #1: 4-Methoxystyrene; bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane for 0.25h; Stage #2: With silica gel In dichloromethane Further stages.;	85%

: 768-60-5
4-methoxyphenylacetylen

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate; 5,5′-bis(trifluoromethyl)-2,2′-bipyridine In 1-methyl-pyrrolidin-2-one; water at 25℃; for 8h; Inert atmosphere; Autoclave;	84%
With [CpRu(6-Ph2P-Py-2-yl)(MeCN)][PF6(1-)]; water In acetone at 70℃; for 24h;	99.8 % Spectr.

: 593-71-5
Chloroiodomethane

: 123-11-5
4-methoxy-benzaldehyde

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
Stage #1: Chloroiodomethane With TurboGrignard In tetrahydrofuran at -20℃; for 0.000277778h; Flow reactor; Stage #2: 4-methoxy-benzaldehyde In tetrahydrofuran at -20℃; for 0.000444444h; Flow reactor; Stage #3: With sodium hydroxide In tetrahydrofuran; water	84%

: 80105-78-8
(p-methoxybenzyl)pentacarbonylmanganese(I)

: 104419-63-8, 61477-64-3
HMn(CO)4(P(CH3)2C6H5)

A: 5703-26-4
4-Methoxyphenylacetaldehyde

: 50540-29-9
nonacarbonyl(dimethylphenylphosphine)dimanganese

Conditions

Conditions	Yield
With carbon monoxide; Triphenylphosphine oxide In benzene-d6 Kinetics; High Pressure; in C6D6 at 45°C, initial concn. ranges were 3.8E-3 to 2.4E-2 M p-MeOC6H4CH2Mn(CO)5, 3.3E-2 to 0.16 M HMn(CO)4(PMe2Ph) (typically 10-fold excess), 0.040 to 0.30 M OPPh3, and 1.1 to 2.3 atm (8.1E-3 to 1.7E-2 M) of CO; followed by NMR and FTIR;	A 80% B >99

...Expand

: 872-36-6
vinylene carbonate

: 5720-07-0
4-methoxyphenylboronic acid

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
Stage #1: 4-methoxyphenylboronic acid With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; tetrahydroxydiboron; 1,3-bis(bis(4-methoxyphenyl)phosphino)propane; Hexamethylbenzene In 1,2-dichloro-ethane at 25℃; for 0.0166667h; Schlenk technique; Inert atmosphere; Stage #2: vinylene carbonate In water at 90℃; for 1h; Sealed tube;	72%

: 637-69-4
4-Methoxystyrene

A: 6388-72-3
2-(4-methoxyphenyl)oxirane

B: 5703-26-4
4-Methoxyphenylacetaldehyde

C: 123-11-5
4-methoxy-benzaldehyde

Conditions

Conditions	Yield
With dihydrogen peroxide for 5h; Catalytic behavior;	A 69% B 9% C 22%
With 2,6-dichloropyridine N-oxide; carbonyl(1,4,8,11,15,18,22,25-octaisopentylphthalocyaninato)ruthenium(II) In toluene at 90℃; for 24h; Catalytic behavior; Reagent/catalyst; Inert atmosphere;	A 64 %Chromat. B 13 %Chromat. C 21 %Chromat.

...Expand

: 637-69-4
4-Methoxystyrene

A: 5703-26-4
4-Methoxyphenylacetaldehyde

B: 123-11-5
4-methoxy-benzaldehyde

Conditions

Conditions	Yield
With 4-methylpyridine-1-oxide; oxochromium(V) complex of dichloro tetramethylsalen IIf In acetonitrile at 25℃;	A 19% B 65%
With pyridine N-oxide; oxochromium(V) complex of dichloro tetramethylsalen IIf In acetonitrile at 23℃; Rate constant; Product distribution; Mechanism; effect of donor ligands on the rate of further olefins; ligand-induced cleavage of olefins by oxochromium(V); (18)O-labeling studies of oxochromium(V);
With 5C16H36N(1+)(x)H2OMnO39SiW11(5-); dihydrogen peroxide In water; acetonitrile at 80℃; for 6h;

: 140463-18-9
(E)-4-methoxyphenylacetaldehyde O-methyloxime

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With formaldehyd; Amberlyst 15 In water; acetone for 29h; Ambient temperature;	65%

: 128224-91-9
(E)-2-(4-methoxyphenyl)acetaldehyde oxime

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With ozone In dichloromethane at -78℃; for 0.166667h; Inert atmosphere;	65%

: 1-(4-hydroxy-3,5-dimethoxyphenyl)-2-(4-methoxyphenoxy)-1,3-propanediol

A: 5703-26-4
4-Methoxyphenylacetaldehyde

B: 123-11-5
4-methoxy-benzaldehyde

C: 134-96-3
syringic aldehyde

Conditions

Conditions	Yield
With oxygen; vanadium(V) oxytriisopropoxide In acetonitrile at 25 - 40℃; under 760.051 Torr; for 12h; Irradiation; Sealed tube;	A 6% B 38% C 61%

...Expand

: 3179-10-0
1-methoxy-4-(2-nitro-vinyl)-benzene

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With sodium hypophosphite; nickel In ethanol; water at 40 - 60℃; for 2h;	53%

: 40080-87-3
methyl 2-(p-methoxyphenyl)-1-methylthioethyl sulfoxide

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With sulfuric acid; sodium hydrogencarbonate In methanol	53%
With sulfuric acid In ethanol

: 1005-62-5
4-tolyl vinyl ether

: 104-94-9
4-methoxy-aniline

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
Stage #1: 4-methoxy-aniline With hydrogenchloride; sodium nitrite In water Stage #2: 4-tolyl vinyl ether With sodium hydrogencarbonate; calcium carbonate; copper dichloride In water; acetone at 25 - 30℃; pH=3 - 4;	49%

: 4693-91-8
4-methoxyphenyl-acetic chloride

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium tetrahydroborate; cadmium(II) chloride In acetonitrile at -5℃; for 0.05h;	48%
Stage #1: 4-methoxyphenyl-acetic chloride With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium tetrahydroborate; N,N-dimethyl-formamide; cadmium(II) chloride In acetonitrile at -5 - 0℃; for 0.666667h; Stage #2: With hydrogenchloride; water In acetonitrile pH=3; Product distribution / selectivity;	48%
Rusenmund reduction;

: 15226-74-1, 61091-28-9, 61117-58-6
dicobalt octacarbonyl

: 121203-13-2
Trifluoro-methanesulfonic acid 4-methoxy-benzyl ester

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With triethylsilane; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium acetate In acetonitrile at 25℃; for 16h; Schlenk technique; Inert atmosphere;	47%

: 17131-20-3
3-(4′-methoxyphenyl)-prop-1,2-diol

: 5703-26-4
4-Methoxyphenylacetaldehyde

Conditions

Conditions	Yield
With lead(IV) acetate In benzene Ambient temperature;	45%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 762-04-9
phosphonic acid diethyl ester

: diethyl 1-hydroxy-2-(4-methoxyphenyl)ethylphosphonate

Conditions

Conditions	Yield
With sodium ethanolate In diethyl ether at -35℃; for 0.166667h;	99%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 1197-58-6
1-(isocyanomethyl)-4-methoxybenzene

: 64-19-7
acetic acid

: 1569843-05-5
C20H23NO5

Conditions

Conditions	Yield
In dichloromethane at 20℃; Passerini Condensation;	99%

...Expand

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 298-12-4
Glyoxilic acid

: 184376-10-1
5-hydroxy-4-(4-methoxy-phenyl)-5H-furan-2-one

Conditions

Conditions	Yield
With morpholin hydrochloride In 1,4-dioxane; water for 24h; Heating / reflux;	98%
With water; morpholin hydrochloride In 1,4-dioxane for 24h; Reflux;	98%

: 110-91-8
morpholine

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 80743-36-8
4-[(E)-2-(4-Methoxy-phenyl)-vinyl]-morpholine

Conditions

Conditions	Yield
In chloroform at 20℃; for 3h; Molecular sieve;	96%
In benzene Heating;	86%
In chloroform at 20℃; for 5h; Molecular sieve; Schlenk technique;

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 20469-65-2
1-bromo-3,5-dimethoxybenzene

: 153139-20-9
(+/-)-1-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanol

Conditions

Conditions	Yield
Stage #1: 1-bromo-3,5-dimethoxybenzene With iodine; magnesium In tetrahydrofuran for 0.5h; Heating; Stage #2: 4-Methoxyphenylacetaldehyde In tetrahydrofuran for 0.5h; Grignard reaction; Heating;	96%
With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;	75%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 101871-19-6
(2-cyclohex-1-enyl-ethyl)-methyl-amine

: 118646-96-1
(2-cyclohex-1-enyl-ethyl)-(4-methoxy-styryl)-methyl-amine

Conditions

Conditions	Yield
In toluene	95.3%
With diethyl ether

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 28819-30-9
benzamidrazone

: 934814-05-8
3-phenyl-5-(p-methoxybenzene)-1,2,4-triazine

Conditions

Conditions	Yield
Stage #1: 4-Methoxyphenylacetaldehyde With iodine; dimethyl sulfoxide at 100℃; for 2h; Green chemistry; Stage #2: benzamidrazone at 100℃; for 1h; Green chemistry;	95%

: 5653-30-5
2-[1,3]dithiolan-2-ylidene-1-phenyl-ethanone

: 5703-26-4
4-Methoxyphenylacetaldehyde

: (E)-2-(1,3-dithiolan-2-ylidene)-4-(4-methoxyphenyl)-1-phenylbut-3-en-1-one

Conditions

Conditions	Yield
With methanol; aluminum (III) chloride In acetonitrile at 80℃; for 6h;	94%

: 109-80-8
1.3-propanedithiol

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 74447-45-3
2-(4-methoxyphenyl)methyl-1,3-dithiane

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane at 0 - 20℃; Molecular sieve;	93%
With boron trifluoride diethyl etherate In dichloromethane; water at 0 - 20℃; for 14h; Molecular sieve; Inert atmosphere;	91%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 622-37-7
Phenyl azide

: 68809-41-6
4-(4-methoxyphenyl)-1-phenyl-1H-[1,2,3]triazole

Conditions

Conditions	Yield
With 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; potassium hydroxide at 20℃; for 0.666667h; Green chemistry; regioselective reaction;	92%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dimethyl sulfoxide at 25℃; for 0.5h; regioselective reaction;	90%
In dimethyl sulfoxide at 20℃; for 1h;	80%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: C14H21N

: 146098-99-9
(2S)-(-)-3,4-dimethyl-2-<(p-methoxyphenyl)methyl>-1-<(1R)-1-phenylethyl>-1,2,5,6-tetrahydropyridine

Conditions

Conditions	Yield
With polyphosphoric acid at 45℃; for 18h; Inert atmosphere;	91%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 1672-34-0
3,6-dimethylthio-1,2,4,5-tetrazine

: 69466-83-7
5-(p-methoxyphenyl)-3-methylsulfanyl-1,2,4-triazine

Conditions

Conditions	Yield
With pyrrolidine; 1,1,1,3',3',3'-hexafluoro-propanol at 25℃;	91%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 77287-34-4, 77287-35-5, 60100-09-6
formamide

: 56100-69-7
N-[2-(4-methoxyphenyl)ethyl]formamide

Conditions

Conditions	Yield
With formic acid at 180℃; for 2h; Leukardt-Wallach Amination;	90%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 762292-75-1
2,2-difluoro-2-(4-methoxyphenyl)ethanol

Conditions

Conditions	Yield
Stage #1: 4-Methoxyphenylacetaldehyde With L-proline In N,N-dimethyl acetamide at 20℃; for 0.5h; Stage #2: With N-fluorobis(benzenesulfon)imide In N,N-dimethyl acetamide at 20℃; for 4h;	90%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 298-12-4
Glyoxilic acid

: C11H10O4

Conditions

Conditions	Yield
With phosphoric acid at 30℃; for 8h;	90%

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 41498-37-7
7,12-O,O'-dimethylcoclaurine

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 20 - 70℃; for 5h; Reagent/catalyst;	89.01%

(4-Methoxyphenyl)acetaldehyde Chemical Properties

Molecular Structure of Benzeneacetaldehyde,4-methoxy- (CAS No.5703-26-4):

Molecular Formula: C₉H₁₀O₂
Molecular Weight: 150.1745
IUPAC Name: 2-(4-Methoxyphenyl)acetaldehyde
CAS No: 5703-26-4
EINECS: 227-191-5
H bond acceptors: 2
H bond donors: 0
Freely Rotating Bonds: 3
Polar Surface Area: 26.3 Å²
Index of Refraction: 1.506
Molar Refractivity: 42.66 cm³
Molar Volume: 143.5 cm³
Surface Tension: 35 dyne/cm
Density: 1.045 g/cm³
Flash Point: 108.5 °C
Enthalpy of Vaporization: 49.3 kJ/mol
Boiling Point: 255.5 °C at 760 mmHg
Vapour Pressure: 0.0162 mmHg at 25°C
Solubility: Slightly soluble in ethanol
Appearance: Pale yellow clear liquid
Canonical SMILES: COC1=CC=C(C=C1)CC=O
InChI: InChI=1S/C9H10O2/c1-11-9-4-2-8(3-5-9)6-7-10/h2-5,7H,6H2,1H3
InChIKey: NRIVMXXOUOBRAG-UHFFFAOYSA-N
Product Categories: Aromatic Aldehydes Derivatives (substituted);Aldehydes;Phenyls Phenyl-Het

(4-Methoxyphenyl)acetaldehyde Specification

Benzeneacetaldehyde,4-methoxy- (CAS No.5703-26-4), it also can be called (4-Methoxyphenyl)acetaldehyde ; Acetaldehyde, 2-(4-methoxyphenyl)- .

Product Name

4-METHOXYPHENYLACETALDEHYDE

Synthetic route

(4-Methoxyphenyl)acetaldehyde Chemical Properties

(4-Methoxyphenyl)acetaldehyde Specification

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